Methanandamide allosterically inhibits in vivo the function of peripheral nicotinic acetylcholine receptors containing the α7-subunit

Journal of Pharmacology and Experimental Therapeutics

Volumn 326, Issue 3, 2008, Pages 912-919

  Baranowska, Urszula ^a   Göthert, Manfred ^a,b   Rudź, Radosław ^a   Malinowska, Barbara ^a  

^a MEDICAL UNIVERSITY OF BIALYSTOK   (Poland)

^b UNIVERSITY OF BONN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

1 (2,4 DICHLOROPHENYL) 5 (4 IODOPHENYL) 4 METHYL N (1 PIPERIDYL) 1H PYRAZOLE 3 CARBOXAMIDE; ATROPINE; CANNABINOID RECEPTOR ANTAGONIST; ENDOCANNABINOID; HEXAMETHONIUM; ISOPRENALINE; METHANANDAMIDE; METHYLLYCACONITINE; NICOTINE; NICOTINIC RECEPTOR; PENTOBARBITAL; URETHAN; ARACHIDONIC ACID DERIVATIVE; BUNGAROTOXIN RECEPTOR; CHRNA7 PROTEIN, RAT; PROTEIN SUBUNIT;

ANESTHESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; ELECTROSTIMULATION; HEART RATE; IN VIVO STUDY; NONHUMAN; PRIORITY JOURNAL; RAT; SINGLE DRUG DOSE; TACHYCARDIA; VAGOTOMY; AGONISTS; ALLOSTERISM; ANIMAL; ANTAGONISTS AND INHIBITORS; CHEMISTRY; COMPARATIVE STUDY; DOSE RESPONSE; DRUG EFFECTS; MALE; PHYSIOLOGY; PROTEIN SUBUNIT; WISTAR RAT;

ALLOSTERIC REGULATION; ALPHA7 NICOTINIC ACETYLCHOLINE RECEPTOR; ANIMALS; ARACHIDONIC ACIDS; DOSE-RESPONSE RELATIONSHIP, DRUG; HEART RATE; MALE; NICOTINE; PROTEIN SUBUNITS; RATS; RATS, WISTAR; RECEPTORS, NICOTINIC;

EID: 53849088589     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.108.140863     Document Type: Article

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