Perfusion of the hypothalamic paraventricular nucleus with N-methyl-D- aspartate produces thromboxane A2 and centrally activates adrenomedullary outflow in rats

Neuroscience

Volumn 96, Issue 3, 2000, Pages 585-590

  Okada, S ^a   Murakami, Y ^a   Nishihara, M ^a   Yokotani, K ^a   Osumi, Y ^a  

^a KOCHI MEDICAL SCHOOL   (Japan)

Author keywords

Adrenomedullary outflow; Hypothalamic paraventricular nucleus; Microdialysis; N methyl D aspartate; Plasma catecholamine; Thromboxane A2

Indexed keywords

ADRENALIN; CATECHOLAMINE; DIZOCILPINE MALEATE; FUREGRELATE; N METHYL DEXTRO ASPARTIC ACID; NORADRENALIN; THROMBOXANE A2; THROMBOXANE B2; URETHAN;

ADRENAL MEDULLA; ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; HYPOTHALAMUS; MALE; MICRODIALYSIS; NONHUMAN; PERFUSION; PRIORITY JOURNAL; RAT; THALAMUS MIDLINE NUCLEUS;

ADRENAL MEDULLA; ANIMALS; BENZOFURANS; CATECHOLAMINES; DIZOCILPINE MALEATE; ENZYME INHIBITORS; EXCITATORY AMINO ACID AGONISTS; EXCITATORY AMINO ACID ANTAGONISTS; MALE; N-METHYLASPARTATE; PARAVENTRICULAR HYPOTHALAMIC NUCLEUS; PERFUSION; RATS; RATS, WISTAR; RECEPTORS, N-METHYL-D-ASPARTATE; THROMBOXANE A2; THROMBOXANE B2; THROMBOXANE-A SYNTHASE;

EID: 0034105598     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(99)00598-9     Document Type: Article

References (39)

1. Anton A.H., Sayre D.F. A study of the factors affecting the aluminum oxide-trihydroxyindole procedure for the analysis of catecholamines. J. Pharmac. exp. Ther. 138:1962;360-375.
2. Bains J.S., Ferguson A.V. Reduced NMDA receptor sensitivity may underlie the resistance of subpopulations of PVN neurons to excitotoxicity. NeuroReport. 8:1997;2101-2105.
3. Choi D.W., Maulucci-Gedde M., Kriegstein A.R. Glutamate neurotoxicity in cortical cell culture. J. Neurosci. 7:1987;357-368.
4. Cotman C.W., Monaghan D.T. Anatomical organization of excitatory amino acid receptors and their properties. Adv. exp. med. Biol. 203:1986;237-252.
5. Daftary S.S., Boudaba C., Szabo K., Tasker J.G. Noradrenergic excitation of magnocellular neurons in the rat hypothalamic paraventricular nucleus via intranuclear glutamatergic circuits. J. Neurosci. 18:1998;10,619-10,628.
6. Dumuis A., Sebben M., Haynes L., Pin J.-P., Bockaert J. NMDA receptors activate the arachidonic acid cascade system in striatal neurons. Nature. 336:1988;68-70.
7. Gajdos M., Spustova V., Sebekoba K., Krivosikova Z., Dzurik R. Effective long-term inhibition of thromboxane production but not of serotonin release in patients with coronary heart disease by 30 mg/d acetylsalicylic acid dosage. Prostaglandins Leukot. Essent. Fatty acids. 59:1998;17-21.
8. Garthwaite J., Charles S.L., Chess-Williams R. Endothelium-derived relaxing factor release on activation of NMDA receptors suggests role as intracellular messenger in the brain. Nature. 336:1988;385-388.
9. Giulian D., Corpuz M., Richmond B., Wendt E., Hall E.R. Activated microglia are the principal glial source of the thromboxane in the central nervous system. Neurochem. Int. 29:1996;65-76.
10. Hamberg M., Samuelsson B. Prostaglandin endoperoxides. Novel transformations of arachidonic acid in human platelets. Proc. natn. Acad. Sci. U.S.A. 71:1974;3400-3404.
11. Hasegawa T., Yokotani K., Okuma Y., Manabe M., Hirakawa M., Osumi Y. Microinjection of alpha-calcitonin gene-related peptide into the hypothalamus activates sympathetic outflow in rats. Jap. J. Pharmac. 61:1993;325-332.
12. Hillarp N.A., Hökfelt B. Evidence of adrenaline and noradrenaline in separate adrenal medullary cells. Acta physiol. scand. 30:1953;55-68.
13. Hsu K.S., Huang C.C., Kan W.M., Gean P.W. TxA2 agonists inhibit high-voltage-activated calcium channels in rat hippocampal CA1 neurons. Am. J. Physiol. 271:1996;C1269-C1277.
14. Kannan H., Hayashida Y., Yamashita H. Increase in sympathetic outflow by paraventricular nucleus stimulation in awake rats. Am. J. Physiol. 256:1989;R1325-R1330.
15. Keller M., Jackisch R., Seregi A., Hertting G. Comparison of prostanoid forming capacity of neuronal and astroglial cells in primary cultures. Neurochem. Int. 7:1985;655-665.
16. Lazarewicz J.W., Wroblewski J.T., Palmer M.E., Costa E. Activation of N-methyl-D-aspartate-sensitive glutamate receptors stimulates arachidonic acid release in primary cultures of cerebellar granule cells. Neuropharmacology. 27:1988;765-769.
17. Lazarewicz J.W., Salinska E. N-Methyl-D-aspartate-evoked release of cyclo-oxygenase products in rabbit hippocampus: an in vivo microdialysis study. J. Neurosci. Res. 40:1995;660-666.
18. Maione S., Vitagliano S., Berrino L., Lampa E., Rossi F. Participation of arginine vasopressin-mediated and adrenergic system-mediated mechanism in the hypertension induced by intracerebroventricular administration of NMDA in freely moving rats. Neuropharmacology. 31:1992;403-407.
19. Martin D.S., Haywood J.R. Sympathetic nervous system activation by glutamate injections into the paraventricular nucleus. Brain Res. 577:1992;261-267.
20. Montague P.R., Gancayco C.D., Winn M.J., Marchase R.B., Friedlander M.J. Role of NO production in NMDA receptor-mediated neurotransmitter release in cerebral cortex. Science. 263:1994;973-977.
21. Murakami Y., Yokotani K., Okuma Y., Osumi Y. Thromboxane A2 is involved in the nitric oxide-induced central activation of adrenomedullary outflow in rats. Neuroscience. 87:1998;197-205.
22. Murakami Y., Yokotani K., Okada S., Osumi Y. Thromboxane A2 mimetics activate central adrenomedullary outflow in rats. Jap. J. Pharmac. 79:(Suppl. I):1999;233P.
23. Namba T., Sugimoto Y., Hirata M., Hayashi Y., Honda A., Watanabe A., Negishi M., Ichikawa A., Narumiya S. Mouse thromboxane A2 receptor: cDNA cloning, expression and northern blot analysis. Biochem. biophys. Res. Commun. 184:1992;1197-1203.
24. Okuma Y., Yokotani K., Osumi Y. Chemical sympathectomy with 6-hydroxydopamine potentiates intracerebroventricularly applied bombesin- induced increase in plasma adrenaline. Life Sci. 49:1991;1611-1618.
25. Paarlberg K.M., de Jong C.L., van Geijn H.P., van Kamp G.J., Heinen A.G., Dekker G.A. Vasoactive mediators in pregnancy-induced hypertensive disorders: a longitudinal study. Am. J. Obstet. Gynecol. 179:1998;1559-1564.
26. Patel P.M., Drummond J.C., Cole D.J., Yaksh T.L. Differential temperature sensitivity of ischemia-induced glutamate release and eicosanoid production in rats. Brain Res. 650:1994;205-211.
27. Paxinos G. and Watson C. (1986) The Rat Brain in Stereotaxic Coodinates. Academic, San Diego.
28. Petralia R.S., Yokotani N., Wenthold R.J. Light and electron microscope distribution of the NMDA receptor subunit NMDAR1 in the rat nervous system using a selective anti-peptide antibody. J. Neurosci. 14:1994;667-696.
29. Reilly M., Fitzgerald G.A. Cellular activation by thromboxane A2 and other eicosanoids. Eur. Heart J. 14:1993;88-93.
30. Salvemini D., Misko T.P., Masferrer J.L., Seibert K., Currie M.G., Needleman P. Nitric oxide activates cyclooxygenase enzymes. Proc. natn. Acad. Sci. U.S.A. 90:1993;7240-7244.
31. Sanfeliu C., Hunt A., Patel A.J. Exposure to N-methyl-D-aspartate increases release of arachidonic acid in primary cultures of rat hippocampal neurons and not in astrocytes. Brain Res. 526:1990;241-248.
32. Shen R.-F., Tai H.-H. Thromboxanes: synthase and receptors. J. biomed. Sci. 5:1998;153-172.
33. Swanson L.W., Sawchenko P.E. Hypothalamic integration: organization of the paraventricular and supraoptic nuclei. A. Rev. Neurosci. 6:1983;269-324.
34. Tone Y., Miyata A., Hara S., Yukawa S., Tanabe T. Abundant expression of thromboxane synthase in rat macrophages. Fedn Eur. biochem. Socs Lett. 340:1994;241-244.
35. Vanicḱy I., Marsala M., Yaksh T.L. Neurodegeneration induced by reversed microdialysis of NMDA; a quantitative model for excitotoxicity in vivo. Brain Res. 789:1998;347-350.
36. Wood C.E., Cudd T.A., Kane C., Engelke K. Fetal ACTH and blood pressure responses to thromboxane mimetic U-46619. Am. J. Physiol. 265:1993;R858-R862.
37. Wood C.E., Purinton S., Cudd T.A. Immunoreactive thromboxane synthase is measurable in ovine fetal hypothalamus as early as 86 days' gestation. Prostaglandins. 54:1997;569-579.
38. Yergey J.A., Heyes M.P. Brain eicosanoid formation following acute penetration injury as studied by in vivo microdialysis. J. cerebr. Blood Flow Metab. 10:1990;143-146.
39. Yokotani K., Nishihara M., Murakami Y., Hasegawa T., Okuma Y., Osumi Y. Elevation of plasma noradrenaline levels in urethane-anesthetized rats by activation of central prostanoid EP3 receptors. Br. J. Pharmac. 115:1995;672-676.