메뉴 건너뛰기




Volumn 136, Issue 7, 2010, Pages 1089-1099

Differential sensitivity of human endometrial carcinoma cells with different PTEN expression to mitogen-activated protein kinase signaling inhibits and implications for therapy

Author keywords

ATF 2; Endometrial carcinoma; Mitogen activated protein kinase pathway; PTEN; SB203580

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ACTIVATING TRANSCRIPTION FACTOR 2; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; SMALL INTERFERING RNA;

EID: 77953230718     PISSN: 01715216     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00432-009-0756-4     Document Type: Article
Times cited : (5)

References (28)
  • 1
    • 33846509838 scopus 로고    scopus 로고
    • Regulation of the phosphatidylinositol 3-Kinase-Akt and the mitogen-activated protein kinase pathways by ursolic acid in human endometrial cancer cells
    • DOI 10.1271/bbb.60288
    • Y Achiwa K Hasegawa Y Udagawa 2007 Regulation of the phosphatidy- linositol 3-kinase-Akt and the mitogen-activated protein kinase pathways by ursolic acid in human endometrial cancer cells Biosci Biotechnol Biochem 71 31 37 10.1271/bbb.60288 1:CAS:528:DC%2BD2sXhs1Wltrg%3D 17213663 (Pubitemid 46155142)
    • (2007) Bioscience, Biotechnology and Biochemistry , vol.71 , Issue.1 , pp. 31-37
    • Achiwa, Y.1    Hasegawa, K.2    Udagawa, Y.3
  • 2
    • 7644223136 scopus 로고    scopus 로고
    • P38 MAP kinase's emerging role as a tumor suppressor
    • DOI 10.1016/S0065-230X(04)92005-2, PII S0065230X04920052
    • DV Bulavin AJ Fornace Jr 2004 p38 MAP kinase's emerging role as a tumor suppressor Adv Cancer Res 92 95 118 10.1016/S0065-230X(04)92005-2 1:CAS:528:DC%2BD2MXivVyhsbk%3D 15530558 (Pubitemid 39458114)
    • (2004) Advances in Cancer Research , vol.92 , pp. 95-118
    • Bulavin, D.V.1    Fornace Jr., A.J.2
  • 3
    • 33644513730 scopus 로고    scopus 로고
    • Beyond PTEN mutations: The PI3K pathway as an integrator of multiple inputs during tumorigenesis
    • DOI 10.1038/nrc1819, PII N1819
    • M Cully H You AJ Levine TW Mak 2006 Beyond PTEN mutations: the PI3K pathways as an integrator of multiple inputs during tumorigenesis Nat Rev Cancer 6 184 192 10.1038/nrc1819 1:CAS:528:DC%2BD28Xhslelt78%3D 16453012 (Pubitemid 43292562)
    • (2006) Nature Reviews Cancer , vol.6 , Issue.3 , pp. 184-192
    • Cully, M.1    You, H.2    Levine, A.J.3    Mak, T.W.4
  • 4
    • 6944238452 scopus 로고    scopus 로고
    • Reduced PTEN expression in breast cancer cells confers susceptibility to inhibitors of the PI3 kinase/Akt pathway
    • DeGraffenried LA, Fulcher L, Friedrichs WE, Grunwald V, Ray RB, Hidalgo M (2004) Reduced PTEN expression in breast cancer cells confers susceptibility to inhibitors of the PI3 kinase/Akt pathway. Ann Oncol 15:1510-1516
    • (2004) Ann Oncol , vol.15 , pp. 1510-1516
    • Degraffenried, L.A.1    Fulcher, L.2    Friedrichs, W.E.3    Grunwald, V.4    Ray, R.B.5    Hidalgo, M.6
  • 5
  • 6
    • 33750576103 scopus 로고    scopus 로고
    • Molecular and pathologic aspects of endometrial carcinogenesis
    • DOI 10.1200/JCO.2006.06.7173
    • JL Hecht GL Mutter 2006 Molecular and pathologic aspects of endometrial carcinogenesis J Clin Oncol 24 4783 4791 10.1200/JCO.2006.06.7173 1:CAS:528:DC%2BD28XhtFynsrrO 17028294 (Pubitemid 46630943)
    • (2006) Journal of Clinical Oncology , vol.24 , Issue.29 , pp. 4783-4791
    • Hecht, J.L.1    Mutter, G.L.2
  • 7
    • 35848938280 scopus 로고    scopus 로고
    • P38α: A suppressor of cell proliferation and tumorigenesis
    • 1:CAS:528:DC%2BD2sXhsVahsbfF 17957136
    • L Hui L Bakiri E Stepniak EF Wagner 2007 p38α: a suppressor of cell proliferation and tumorigenesis Cell Cycle 6 2429 2433 1:CAS:528: DC%2BD2sXhsVahsbfF 17957136
    • (2007) Cell Cycle , vol.6 , pp. 2429-2433
    • Hui, L.1    Bakiri, L.2    Stepniak, E.3    Wagner, E.F.4
  • 9
    • 34249304804 scopus 로고    scopus 로고
    • Phosphatase and tensin homologue deficiency in glioblastoma confers resistance to radiation and temozolomide that is reversed by the protease inhibitor nelfinavir
    • DOI 10.1158/0008-5472.CAN-06-3398
    • Z Jiang N Pore GJ Cerniglia R Mick MM Georgescu EJ Bernhard SM Hahn AK Gupta A Maity 2007 Phosphatase and tensin homologue deficiency in glioblastoma confers resistance to radiation and temozolomide that is reversed by the protease inhibitor nelfinavir Cancer Res 67 4467 4473 10.1158/0008-5472.CAN-06- 3398 1:CAS:528:DC%2BD2sXltVyrtr0%3D 17483362 (Pubitemid 46815097)
    • (2007) Cancer Research , vol.67 , Issue.9 , pp. 4467-4473
    • Jiang, Z.1    Pore, N.2    Cerniglia, G.J.3    Mick, R.4    Georgescu, M.-M.5    Bernhard, E.J.6    Hahn, S.M.7    Gupta, A.K.8    Maity, A.9
  • 10
    • 67649970221 scopus 로고    scopus 로고
    • Melatonin induces apoptotic death in LNCaP cells via p38 and JNK pathways: Therapeutic implications for prostate cancer
    • 10.1111/j.1600-079X.2009.00682.x 1:CAS:528:DC%2BD1MXovVKgu7c%3D 19522739
    • SS Joo Y-M Yoo 2009 Melatonin induces apoptotic death in LNCaP cells via p38 and JNK pathways: therapeutic implications for prostate cancer J Pineal Res 47 8 14 10.1111/j.1600-079X.2009.00682.x 1:CAS:528:DC%2BD1MXovVKgu7c%3D 19522739
    • (2009) J Pineal Res , vol.47 , pp. 8-14
    • Joo, S.S.1    Yoo, Y.-M.2
  • 11
    • 52749085743 scopus 로고    scopus 로고
    • Targeted manipulation of apoptosis in cancer therapy
    • 10.1016/S1470-2045(08)70209-2
    • AC Justin SG Eckhardt DR Camidge 2008 Targeted manipulation of apoptosis in cancer therapy Lancet 9 1002 1011 10.1016/S1470-2045(08)70209-2
    • (2008) Lancet , vol.9 , pp. 1002-1011
    • Justin, A.C.1    Eckhardt, S.G.2    Camidge, D.R.3
  • 12
    • 65849180154 scopus 로고    scopus 로고
    • Loss of PTEN function may account for reduced proliferation pathway sensitivity to LY294002 in human prostate and bladder cancer cells
    • 10.1007/s00432-008-0465-4 1:CAS:528:DC%2BD1cXhsFejtbjF 18726116
    • S Kanda H Kanetake Y Miyata 2009 Loss of PTEN function may account for reduced proliferation pathway sensitivity to LY294002 in human prostate and bladder cancer cells J Cancer Res Clin Oncol 135 303 311 10.1007/s00432-008- 0465-4 1:CAS:528:DC%2BD1cXhsFejtbjF 18726116
    • (2009) J Cancer Res Clin Oncol , vol.135 , pp. 303-311
    • Kanda, S.1    Kanetake, H.2    Miyata, Y.3
  • 14
    • 15544369937 scopus 로고    scopus 로고
    • Activation of PI3K/Akt pathway by PTEN reduction and PIK3CA mRNA amplification contributes to cisplatin resistance in an ovarian cancer cell line
    • DOI 10.1016/j.ygyno.2004.11.051
    • S Lee EJ Choi C Jin DH Kim 2005 Activation of PI3K/Akt pathway by PTEN reduction and PIK3CA mRNA amplification contributes to cisplatin resistance in an ovarian cancer cell line Gynecol Oncol 97 26 34 10.1016/j.ygyno.2004.11.051 1:CAS:528:DC%2BD2MXis1GrsL4%3D 15790433 (Pubitemid 40403670)
    • (2005) Gynecologic Oncology , vol.97 , Issue.1 , pp. 26-34
    • Lee, S.1    Choi, E.-J.2    Jin, C.3    Kim, D.-H.4
  • 15
    • 4344684649 scopus 로고    scopus 로고
    • PTEN function: How normal cells control it and tumour cells lose it
    • DOI 10.1042/BJ20040825
    • NR Leslie CP Downes 2004 PTEN function: how normal cells control it and tumour cells lose it Biochem J 382 1 11 10.1042/BJ20040825 1:CAS:528: DC%2BD2cXmsVChsLo%3D 15193142 (Pubitemid 39141560)
    • (2004) Biochemical Journal , vol.382 , Issue.1 , pp. 1-11
    • Leslie, N.R.1    Downes, C.P.2
  • 16
    • 22144449634 scopus 로고    scopus 로고
    • Activation of cyclin D1 by estradiol and spermine in MCF-7 breast cancer cells: A mechanism involving the p38 MAP kinase and phosphorylation of ATF-2
    • 1:CAS:528:DC%2BD2MXmtleltbc%3D 16050133
    • JS Lewis V Vijayanathan TJ Thomas RG Pestell C Albanese MA Gallo T Thomas 2005 Activation of cyclin D1 by estradiol and spermine in MCF-7 breast cancer cells: a mechanism involving the p38 MAP kinase and phosphorylation of ATF-2 Oncol Res 15 113 128 1:CAS:528:DC%2BD2MXmtleltbc%3D 16050133
    • (2005) Oncol Res , vol.15 , pp. 113-128
    • Lewis, J.S.1    Vijayanathan, V.2    Thomas, T.J.3    Pestell, R.G.4    Albanese, C.5    Gallo, M.A.6    Thomas, T.7
  • 17
    • 21344456180 scopus 로고    scopus 로고
    • The RAS/RAF/MEK/ERK and PI3K/AKT signaling pathways present molecular targets for the effective treatment of advanced melanoma
    • 10.2741/1755
    • F Meier B Schittek S Busch C Garbe K Smalley K Satyamoorthy G Li M Herlyn 2005 The RAS/RAF/MEK/ERK and PI3K/AKT signaling pathways present molecular targets for the effective treatment of advanced melanoma Front Biosci 1 2986 3001 10.2741/1755
    • (2005) Front Biosci , vol.1 , pp. 2986-3001
    • Meier, F.1    Schittek, B.2    Busch, S.3    Garbe, C.4    Smalley, K.5    Satyamoorthy, K.6    Li, G.7    Herlyn, M.8
  • 19
    • 33847369903 scopus 로고    scopus 로고
    • Systemic therapy in metastatic or recurrent endometrial cancer
    • DOI 10.1016/j.ctrv.2006.10.007, PII S0305737206002088
    • D Pectasides E Pectasides T Economopoulos 2007 Systemic therapy in metastatic or recurrent endometrial cancer Cancer Treat Rev 33 177 190 10.1016/j.ctrv.2006.10.007 1:CAS:528:DC%2BD2sXitl2jtL0%3D 17196749 (Pubitemid 46343104)
    • (2007) Cancer Treatment Reviews , vol.33 , Issue.2 , pp. 177-190
    • Pectasides, D.1    Pectasides, E.2    Economopoulos, T.3
  • 20
    • 38449083549 scopus 로고    scopus 로고
    • Apoptotic effects of signal transduction inhibitors on human tumor cells with different PTEN expression
    • 1:CAS:528:DC%2BD2sXhtlKhsrzI 17914589
    • G Pfeiler F Horn C Lattrich S Klappenberger O Ortmann O Treeck 2007 Apoptotic effects of signal transduction inhibitors on human tumor cells with different PTEN expression Oncol Rep 18 1305 1309 1:CAS:528:DC%2BD2sXhtlKhsrzI 17914589
    • (2007) Oncol Rep , vol.18 , pp. 1305-1309
    • Pfeiler, G.1    Horn, F.2    Lattrich, C.3    Klappenberger, S.4    Ortmann, O.5    Treeck, O.6
  • 21
    • 33846821915 scopus 로고    scopus 로고
    • P53-deficient cells rely on ATM- and ATR-mediated checkpoint signaling through the p38MAPK/MK2 pathway for survival after DNA damage
    • DOI 10.1016/j.ccr.2006.11.024, PII S1535610806003825
    • HC Reinhardt AS Aslanian JA Lees MB Yaffe 2007 p53-Deficient cells rely on ATM-and ATR-mediated checkpoint signaling through the p38MAPK/MMK2 pathway for survival after DNA damage Cancer Cell 11 175 189 10.1016/j.ccr.2006.11.024 1:CAS:528:DC%2BD2sXitVartLc%3D 17292828 (Pubitemid 46209849)
    • (2007) Cancer Cell , vol.11 , Issue.2 , pp. 175-189
    • Reinhardt, H.C.1    Aslanian, A.S.2    Lees, J.A.3    Yaffe, M.B.4
  • 23
    • 1442278729 scopus 로고    scopus 로고
    • 2α Receptor in Human Endometrial Adenocarcinoma: Regulation of Proliferation by Activation of the Epidermal Growth Factor Receptor and Mitogen-Activated Protein Kinase Signaling Pathways
    • DOI 10.1210/jc.2003-031434
    • KJ Sales SA Milne AR Williams RA Anderson HN Jabbour 2004 Expression, localization, and signaling of prostaglandin F2 receptor in human endometrial adenocarcinoma: regulation of proliferation by activation of the epidermal growth factor receptor and mitogen-activated protein kinase signaling pathways J Clin Endocrinol Metab 89 986 993 10.1210/jc.2003-031434 1:CAS:528: DC%2BD2cXhsFOjtbg%3D 14764825 (Pubitemid 38269922)
    • (2004) Journal of Clinical Endocrinology and Metabolism , vol.89 , Issue.2 , pp. 986-993
    • Sales, K.J.1    Milne, S.A.2    Williams, A.R.W.3    Anderson, R.A.4    Jabbour, H.N.5
  • 25
    • 0038306995 scopus 로고    scopus 로고
    • Multivariate independent prognostic factors in endometrial carcinoma: A clinicopathologic study in 181 patients: 10 Years experience at the Department of Obstetrics and Gynecology of the Mainz University
    • DOI 10.1046/j.1525-1438.2003.13021.x
    • E Steiner O Eicher J Sagemüller M Schmidt H Pilch B Tanner JG Hengstler M Hofmann PG Knapstein 2003 Multivariate independent prognostic factors in endometrial carcinoma: a clinicopathologic study in 181 patients: 10 years experience at the Department of Obstetrics and Gynecology of the Mainz University Int J Gynecol Cancer 13 197 203 10.1046/j.1525-1438.2003.13021.x 1:STN:280:DC%2BD3s7kt1eluw%3D%3D 12657124 (Pubitemid 37055478)
    • (2003) International Journal of Gynecological Cancer , vol.13 , Issue.2 , pp. 197-203
    • Steiner, E.1    Eicher, O.2    Sagemuller, J.3    Schmidt, M.4    Pilch, H.5    Tanner, B.6    Hengstler, J.G.7    Hofmann, M.8    Knapstein, P.G.9
  • 26
    • 60149093582 scopus 로고    scopus 로고
    • Non-classical p38 MAP kinase functions: Cell cycle checkpoints and survival
    • 1:CAS:528:DC%2BD1MXnsl2rtb4%3D 19159010
    • TM Thornton M Rincon 2009 Non-classical p38 MAP kinase functions: cell cycle checkpoints and survival Int J Biol Sci 5 44 51 1:CAS:528: DC%2BD1MXnsl2rtb4%3D 19159010
    • (2009) Int J Biol Sci , vol.5 , pp. 44-51
    • Thornton, T.M.1    Rincon, M.2
  • 28
    • 67749117934 scopus 로고    scopus 로고
    • Signal integration by JNK and p38 MAPK pathways in cancer development
    • 10.1038/nrc2694 1:CAS:528:DC%2BD1MXovFymu7w%3D 19629069
    • EF Wagner AR Nebreda 2009 Signal integration by JNK and p38 MAPK pathways in cancer development Nat Rev Cancer 9 537 549 10.1038/nrc2694 1:CAS:528:DC%2BD1MXovFymu7w%3D 19629069
    • (2009) Nat Rev Cancer , vol.9 , pp. 537-549
    • Wagner, E.F.1    Nebreda, A.R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.