메뉴 건너뛰기




Volumn 18, Issue 5, 2007, Pages 1305-1309

Apoptotic effects of signal transduction inhibitors on human tumor cells with different PTEN expression

Author keywords

Apoptosis; Cancer cells; Mitogen activated protein kinase; PTEN; Targeted therapy

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; ANTIESTROGEN; ANTINEOPLASTIC AGENT; ENZYME INHIBITOR; EPIDERMAL GROWTH FACTOR RECEPTOR; FLAVONOID; GEFITINIB; HER1 PROTEIN, HUMAN; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE (CALCIUM,CALMODULIN); PTEN PROTEIN, HUMAN; QUINAZOLINE DERIVATIVE; TAMOXIFEN; UNCLASSIFIED DRUG;

EID: 38449083549     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.18.5.1305     Document Type: Article
Times cited : (15)

References (20)
  • 1
    • 0029303048 scopus 로고
    • Effects of tamoxifen on growth and apoptosis of estrogen-dependent and -independent human breast cancer cells
    • Perry RR, Kang Y and Greaves B: Effects of tamoxifen on growth and apoptosis of estrogen-dependent and -independent human breast cancer cells. Ann Surg Oncol 2: 238-245, 1995.
    • (1995) Ann Surg Oncol , vol.2 , pp. 238-245
    • Perry, R.R.1    Kang, Y.2    Greaves, B.3
  • 2
    • 1942474587 scopus 로고    scopus 로고
    • The HER-2-Targeting Antibodies Trastuzumab and Pertuzumab Synergistically Inhibit the Survival of Breast Cancer Cells
    • DOI 10.1158/0008-5472.CAN-03-3856
    • Nahta R, Hung MC and Esteva FJ: The HER-2-targeting antibodies trastuzumab and pertuzumab synergistically inhibit the survival of breast cancer cells. Cancer Res 64: 2343-2346, 2004. (Pubitemid 38523885)
    • (2004) Cancer Research , vol.64 , Issue.7 , pp. 2343-2346
    • Nahta, R.1    Hung, M.-C.2    Esteva, F.J.3
  • 5
    • 23844530876 scopus 로고    scopus 로고
    • Reduced expression of PTEN protein and its prognostic implications in invasive ductal carcinoma of the breast
    • DOI 10.1159/000086981
    • Tsutsui S, Inoue H, Yasuda K, Suzuki K, Higashi H, Era S and Mori M: Reduced expression of PTEN protein and its prognostic implications in invasive ductal carcinoma of the breast. Oncology 68: 398-404, 2005. (Pubitemid 41160970)
    • (2005) Oncology , vol.68 , Issue.4-6 , pp. 398-404
    • Tsutsui, S.1    Inoue, H.2    Yasuda, K.3    Suzuki, K.4    Higashi, H.5    Era, S.6    Mori, M.7
  • 8
    • 0035869212 scopus 로고    scopus 로고
    • 1 arrest by down-regulating cyclin D1 via its protein phosphatase activity and up-regulating p27 via its lipid phosphatase acitvity in a breast cancer model
    • Weng LP, Brown JL and Eng C: PTEN coordinates G (1) arrest by down-regulating cyclin D1 via its protein phosphatase activity and up-regulating p27 via its lipid phosphatase activity in a breast cancer model. Hum Mol Genet 10: 599-604, 2001. (Pubitemid 32229364)
    • (2001) Human Molecular Genetics , vol.10 , Issue.6 , pp. 599-604
    • Weng, L.-P.1    Brown, J.L.2    Eng, C.3
  • 9
  • 10
    • 0032583122 scopus 로고    scopus 로고
    • Tumor suppressor PTEN inhibits integrin- and growth factor-mediated mitogen-activated protein (MAP) kinase signaling pathways
    • DOI 10.1083/jcb.143.5.1375
    • Gu J, Tamura M and Yamada KM: Tumor suppressor PTEN inhibits integrin- and growth factor-mediated mitogen-activated protein (MAP) kinase signaling pathways. J Cell Biol 143: 1375-1383, 1998. (Pubitemid 28559837)
    • (1998) Journal of Cell Biology , vol.143 , Issue.5 , pp. 1375-1383
    • Gu, J.1    Tamura, M.2    Yamada, K.M.3
  • 11
    • 6944238452 scopus 로고    scopus 로고
    • Reduced PTEN expression in breast cancer cells confers susceptibility to inhibitors of the PI3 kinase/Akt pathway
    • DOI 10.1093/annonc/mdh388
    • DeGraffenried LA, Fulcher L, Friedrichs WE, Grunwald V, Ray RB and Hidalgo M: Reduced PTEN expression in breast cancer cells confers susceptibility to inhibitors of the PI3 kinase/Akt pathway. Ann Oncol 15: 1510-1516, 2004. (Pubitemid 39409742)
    • (2004) Annals of Oncology , vol.15 , Issue.10 , pp. 1510-1516
    • DeGraffenried, L.A.1    Fulcher, L.2    Friedrichs, W.E.3    Grunwald, V.4    Ray, R.B.5    Hidalgo, M.6
  • 12
    • 0035869175 scopus 로고    scopus 로고
    • PTEN inhibits insulin-stimulated MEK/MAPK activation and cell growth by blocking IRS-1 phosphorylation and IRS-1/Grb-2/Sos complex formation in a breast cancer model
    • Weng LP, Smith WM, Brown JL and Eng C: PTEN inhibits insulin-stimulated MEK/MAPK activation and cell growth by blocking IRS-1 phosphorylation and IRS-1/Grb-2/Sos complex formation in a breast cancer model. Hum Mol Genet 10: 605-616, 2001. (Pubitemid 32229365)
    • (2001) Human Molecular Genetics , vol.10 , Issue.6 , pp. 605-616
    • Weng, L.-P.1    Smith, W.M.2    Brown, J.L.3    Eng, C.4
  • 14
    • 0035947728 scopus 로고    scopus 로고
    • The p38 MAPK pathway is required for cell growth inhibition of human breast cancer cells in response to activin
    • Cocolakis E, Lemay S, Ali S and Lebrun JJ: The p38 MAPK pathway is required for cell growth inhibition of human breast cancer cells in response to activin. J Biol Chem 276: 18430-18436, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 18430-18436
    • Cocolakis, E.1    Lemay, S.2    Ali, S.3    Lebrun, J.J.4
  • 15
    • 1542329631 scopus 로고    scopus 로고
    • A p38 inhibitor allows to dissociate differentiation and apoptotic processes triggered upon LIF withdrawal in mouse embryonic stem cells
    • DOI 10.1038/sj.cdd.4401337
    • Duval D, Malaise M, Reinhardt B, Kedinger C and Boeuf H: A p38 inhibitor allows to dissociate differentiation and apoptotic processes triggered upon LIF withdrawal in mouse embryonic stem cells. Cell Death Differ 11: 331-341, 2004. (Pubitemid 38313142)
    • (2004) Cell Death and Differentiation , vol.11 , Issue.3 , pp. 331-341
    • Duval, D.1    Malaise, M.2    Reinhardt, B.3    Kedinger, C.4    Boeuf, H.5
  • 16
    • 13944257829 scopus 로고    scopus 로고
    • 44/42 and p38 mitogen-activated protein kinases potentiate apoptosis induction by sulindac sulfide in human colon carcinoma cells
    • Sun Y and Sinicrope FA: Selective inhibitors of MEK1/ERK44/42 and p38 mitogen-activated protein kinases potentiate apoptosis induction by sulindac sulfide in human colon carcinoma cells. Mol Cancer Ther 4: 51-59, 2005. (Pubitemid 40268066)
    • (2005) Molecular Cancer Therapeutics , vol.4 , Issue.1 , pp. 51-59
    • Sun, Y.1    Sinicrope, F.A.2
  • 17
    • 0036633164 scopus 로고    scopus 로고
    • Constitutive and inducible Akt activity promotes resistance to chemotherapy, trastuzumab, or tamoxifen in breast cancer cells
    • Clark AS, West K, Streicher S and Dennis PA: Constitutive and inducible Akt activity promotes resistance to chemotherapy, trastuzumab, or tamoxifen in breast cancer cells. Mol Cancer Ther 1: 707-717, 2002.
    • (2002) Mol Cancer Ther , vol.1 , pp. 707-717
    • Clark, A.S.1    West, K.2    Streicher, S.3    Dennis, P.A.4
  • 19
    • 0042525911 scopus 로고    scopus 로고
    • Expression of constitutively active Akt-3 in MCF-7 breast cancer cells reverses the estrogen and tamoxifen responsivity of these cells in vivo
    • Faridi J, Wang L, Endemann G and Roth RA: Expression of constitutively active Akt-3 in MCF-7 breast cancer cells reverses the estrogen and tamoxifen responsivity of these cells in vivo. Clin Cancer Res 9: 2933-2939, 2003. (Pubitemid 36993252)
    • (2003) Clinical Cancer Research , vol.9 , Issue.8 , pp. 2933-2939
    • Faridi, J.1    Wang, L.2    Endemann, G.3    Roth, R.A.4
  • 20
    • 13244259196 scopus 로고    scopus 로고
    • Reduced PTEN expression predicts relapse in patients with breast carcinoma treated by tamoxifen
    • DOI 10.1038/modpathol.3800296
    • Shoman N, Klassen S, McFadden A, Bickis MG, Torlakovic E and Chibbar R: Reduced PTEN expression predicts relapse in patients with breast carcinoma treated by tamoxifen. Mod Pathol 18: 250-259, 2005. (Pubitemid 40188633)
    • (2005) Modern Pathology , vol.18 , Issue.2 , pp. 250-259
    • Shoman, N.1    Klassen, S.2    McFadden, A.3    Bickis, M.G.4    Torlakovic, E.5    Chibbar, R.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.