Type-I IFN signaling suppresses an excessive IFN-γ response and thus prevents lung damage and chronic inflammation during Pneumocystis (PC) clearance in CD4 T cell-competent mice

American Journal of Pathology

Volumn 176, Issue 6, 2010, Pages 2806-2818

  Meissner, Nicole ^a   Swain, Steve ^a   McInnerney, Kate ^a   Han, Soo ^a   Harmsen, Allen G ^a  

^a MONTANA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COTRIMOXAZOLE; GAMMA INTERFERON; GAMMA INTERFERON ANTIBODY; GLYCOPROTEIN P 15095; INTERFERON; SUPPRESSOR OF CYTOKINE SIGNALING 1; TUMOR NECROSIS FACTOR ALPHA; ALPHA BETA INTERFERON RECEPTOR; IFNAR1 PROTEIN, MOUSE;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CD4+ T LYMPHOCYTE; CHRONIC INFLAMMATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RESPONSE; DISEASE ASSOCIATION; IMMUNE RECONSTITUTION INFLAMMATORY SYNDROME; IMMUNE RESPONSE; LOEFFLER PNEUMONIA; LUNG CLEARANCE; LUNG FIBROSIS; LUNG INJURY; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OUTCOME ASSESSMENT; PNEUMOCYSTIS; PNEUMOCYSTOSIS; PNEUMONIA; PRIORITY JOURNAL; PROPHYLAXIS; PROTEIN INDUCTION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; UPREGULATION; WILD TYPE; ANIMAL; CHEMISTRY; CYTOLOGY; GENE EXPRESSION PROFILING; GENETICS; HUMAN; IMMUNOLOGY; INFLAMMATION; KNOCKOUT MOUSE; LUNG; LUNG LAVAGE; METABOLISM; MICROBIOLOGY; PATHOLOGY; PNEUMOCYSTIS PNEUMONIA; SCID MOUSE;

ANIMALS; ANTIGENS, CD11C; BRONCHOALVEOLAR LAVAGE FLUID; CD4-POSITIVE T-LYMPHOCYTES; GENE EXPRESSION PROFILING; HUMANS; INFLAMMATION; INTERFERON TYPE I; INTERFERON-GAMMA; LUNG; MICE; MICE, KNOCKOUT; MICE, SCID; MICROARRAY ANALYSIS; PNEUMOCYSTIS; PNEUMONIA, PNEUMOCYSTIS; RECEPTOR, INTERFERON ALPHA-BETA; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 77953198930     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.2353/ajpath.2010.091158     Document Type: Article

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