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Volumn 120, Issue 6, 2010, Pages 1961-1970

Statin-induced Kruppel-like factor 2 expression in human and mouse T cells reduces inflammatory and pathogenic responses

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR; FLUINDOSTATIN; GAMMA INTERFERON; ISOPRENOID; KRUPPEL LIKE FACTOR 2; MEVALONIC ACID; MEVINOLIN; PITAVASTATIN; RETROVIRUS VECTOR; SHORT HAIRPIN RNA; SIMVASTATIN;

EID: 77953185420     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI41384     Document Type: Article
Times cited : (90)

References (39)
  • 1
    • 0030697515 scopus 로고    scopus 로고
    • The LKLF transcription factor is required for normal tunica media formation and blood vessel stabilization during murine embryo-genesis
    • Kuo CT, Veselits ML, Barton KP, Lu MM, Clendenin C, Leiden JM. The LKLF transcription factor is required for normal tunica media formation and blood vessel stabilization during murine embryo-genesis. Genes Dev. 1997;11(22):2996-3006.
    • (1997) Genes Dev , vol.11 , Issue.22 , pp. 2996-3006
    • Kuo, C.T.1    Veselits, M.L.2    Barton, K.P.3    Lu, M.M.4    Clendenin, C.5    Leiden, J.M.6
  • 2
    • 0034884577 scopus 로고    scopus 로고
    • Transcription factor LKLF is sufficient to program T cell quiescence via a c-Myc-dependent pathway
    • Buckley AF, Kuo CT, Leiden JM. Transcription factor LKLF is sufficient to program T cell quiescence via a c-Myc-dependent pathway. Nat Immunol. 2001;2(8):698-704.
    • (2001) Nat Immunol , vol.2 , Issue.8 , pp. 698-704
    • Buckley, A.F.1    Kuo, C.T.2    Leiden, J.M.3
  • 3
    • 7944234615 scopus 로고    scopus 로고
    • WAF1/CIP1
    • DOI 10.1038/sj.onc.1207996
    • Wu J, Lingrel JB. KLF2 inhibits Jurkat T leukemia cell growth via upregulation of cyclin-dependent kinase inhibitor p21WAF1/CIP1. Oncogene. 2004;23(49):8088-8096. (Pubitemid 39531849)
    • (2004) Oncogene , vol.23 , Issue.49 , pp. 8088-8096
    • Wu, J.1    Lingrel, J.B.2
  • 4
    • 0344931885 scopus 로고    scopus 로고
    • Expression of the transcription factor lung Kruppel-like factor is regulated by cytokines and correlates with survival memory T cells in vitro and in vivo
    • Schober SL, Kuo CT, Schluns KS, Lefrancois L, Leiden JM, Jameson SC. Expression of the transcription factor lung Kruppel-like factor is regulated by cytokines and correlates with survival of memory T cells in vitro and in vivo. J Immunol. 1999;163(7):3662-3667. (Pubitemid 29450887)
    • (1999) Journal of Immunology , vol.163 , Issue.7 , pp. 3662-3667
    • Schober, S.L.1    Chay T, K.2    Schluns, K.S.3    Lefrancois, L.4    Leiden, J.M.5    Jameson, S.C.6
  • 6
    • 23844457210 scopus 로고    scopus 로고
    • Kruppel-like factor 2, a novel immediate-early transcriptional factor, regulates IL-2 expression in T lymphocyte activation
    • Wu J, Lingrel JB. Kruppel-like factor 2, a novel immediate-early transcriptional factor, regulates IL-2 expression in T lymphocyte activation. J Immunol. 2005;175(5):3060-3066. (Pubitemid 41170525)
    • (2005) Journal of Immunology , vol.175 , Issue.5 , pp. 3060-3066
    • Wu, J.1    Lingrel, J.B.2
  • 7
    • 33746334804 scopus 로고    scopus 로고
    • Kruppel-like factor 2 regulates thymocyte and T-cell migration
    • Carlson CM, et al. Kruppel-like factor 2 regulates thymocyte and T-cell migration. Nature. 2006;442(7100):299-302.
    • (2006) Nature , vol.442 , Issue.7100 , pp. 299-302
    • Carlson, C.M.1
  • 8
    • 0030823769 scopus 로고    scopus 로고
    • LKLF: A transcriptional regulator of single-positive T cell quiescence and survival
    • Kuo CT, Veselits ML, Leiden JM. LKLF: A transcriptional regulator of single-positive T cell quiescence and survival. Science. 1997;277(5334):1986- 1990.
    • (1997) Science , vol.277 , Issue.5334 , pp. 1986-1990
    • Kuo, C.T.1    Veselits, M.L.2    Leiden, J.M.3
  • 9
    • 39449087305 scopus 로고    scopus 로고
    • Transcription factor KLF2 regulates the migration of naive T cells by restricting chemokine receptor expression patterns
    • DOI 10.1038/ni1565, PII NI1565
    • Sebzda E, Zou Z, Lee JS, Wang T, Kahn ML. Transcription factor KLF2 regulates the migration of naive T cells by restricting chemokine receptor expression patterns. Nat Immunol. 2008;9(3):292-300. (Pubitemid 351267326)
    • (2008) Nature Immunology , vol.9 , Issue.3 , pp. 292-300
    • Sebzda, E.1    Zou, Z.2    Lee, J.S.3    Wang, T.4    Kahn, M.L.5
  • 10
    • 68249134207 scopus 로고    scopus 로고
    • KLF2 transcription-factor deficiency in T cells results in unrestrained cytokine production and upregulation of bystander chemokine receptors
    • Weinreich MA, Takada K, Skon C, Reiner SL, Jameson SC, Hogquist KA. KLF2 transcription-factor deficiency in T cells results in unrestrained cytokine production and upregulation of bystander chemokine receptors. Immunity. 2009;31(1):122-130.
    • (2009) Immunity , vol.31 , Issue.1 , pp. 122-130
    • Weinreich, M.A.1    Takada, K.2    Skon, C.3    Reiner, S.L.4    Jameson, S.C.5    Hogquist, K.A.6
  • 12
    • 0034533147 scopus 로고    scopus 로고
    • Statins as a newly recognized type of immunomodulator
    • DOI 10.1038/82219
    • Kwak B, Mulhaupt F, Myit S, Mach F. Statins as a newly recognized type of immunomodulator. Nat Med. 2000;6(12):1399-1402. (Pubitemid 32001026)
    • (2000) Nature Medicine , vol.6 , Issue.12 , pp. 1399-1402
    • Kwak, B.1    Mulhaupt, F.2    Myit, S.3    Mach, F.4
  • 13
    • 25144522575 scopus 로고    scopus 로고
    • Toward immunomodulatory and anti-inflammatory properties of statins
    • DOI 10.1016/j.tcm.2005.07.002, PII S1050173805001210
    • Arnaud C, Braunersreuther V, Mach F. Toward immunomodulatory and anti-inf lammatory properties of statins. Trends Cardiovasc Med. 2005;15(6):202-206. (Pubitemid 41338006)
    • (2005) Trends in Cardiovascular Medicine , vol.15 , Issue.6 , pp. 202-206
    • Arnaud, C.1    Braunersreuther, V.2    Mach, F.3
  • 16
    • 0035829849 scopus 로고    scopus 로고
    • Locking a leukocyte integrin with statins
    • Frenette PS. Locking a leukocyte integrin with statins. N Engl J Med. 2001;345(19):1419-1421.
    • (2001) N Engl J Med , vol.345 , Issue.19 , pp. 1419-1421
    • Frenette, P.S.1
  • 17
    • 35748945752 scopus 로고    scopus 로고
    • Atorvastatin inhibits T cell activation through 3-hydroxy-3- methylglutaryl coenzyme a reductase without decreasing cholesterol synthesis
    • Blank N, et al. Atorvastatin inhibits T cell activation through 3-hydroxy-3-methylglutaryl coenzyme A reductase without decreasing cholesterol synthesis. J Immunol. 2007;179(6):3613-3621.
    • (2007) J Immunol , vol.179 , Issue.6 , pp. 3613-3621
    • Blank, N.1
  • 19
    • 0029858008 scopus 로고    scopus 로고
    • Lovastatin inhibits T-cell antigen receptor signaling independent of its effects on ras
    • Goldman F, Hohl R, Crabtree J, Lewis-Tibesar K, Koretzky G. Lovastatin inhibits T-cell antigen receptor signaling independent of its effects on ras. Blood. 1996;88(12):4611-4619. (Pubitemid 26419144)
    • (1996) Blood , vol.88 , Issue.12 , pp. 4611-4619
    • Goldman, F.1    Hohl, R.J.2    Crabtree, J.3    Lewis-Tibesar, K.4    Koretzky, G.5
  • 23
    • 34250868932 scopus 로고    scopus 로고
    • Role of Kruppel-like transcription factors in endothelial biology
    • DOI 10.1161/01.RES.0000267856.00713.0a, PII 0000301220070622000004
    • Atkins GB, Jain MK. Role of Kruppel-like transcription factors in endothelial biology. Circ Res. 2007;100(12):1686-1695. (Pubitemid 46987860)
    • (2007) Circulation Research , vol.100 , Issue.12 , pp. 1686-1695
    • Atkins, G.B.1    Jain, M.K.2
  • 24
    • 34548360808 scopus 로고    scopus 로고
    • Biomechanical modulation of endothelial phenotype: Implications for health and disease
    • Garcia-Cardena G, Gimbrone MA Jr. Biomechanical modulation of endothelial phenotype: implications for health and disease. Handb Exp Pharmacol. 2006;(176 pt 2):79-95.
    • (2006) Handb Exp Pharmacol , Issue.176 PART 2 , pp. 79-95
    • Garcia-Cardena, G.1    Gimbrone Jr., M.A.2
  • 25
    • 33749426332 scopus 로고    scopus 로고
    • Shear stress sustains atheroprotective endothelial KLF2 expression more potently than statins through mRNA stabilization
    • van Thienen JV, et al. Shear stress sustains atheroprotective endothelial KLF2 expression more potently than statins through mRNA stabilization. Cardiovasc Res. 2006;72(2):231-240.
    • (2006) Cardiovasc Res , vol.72 , Issue.2 , pp. 231-240
    • Van Thienen, J.V.1
  • 26
    • 41149135364 scopus 로고    scopus 로고
    • Simvastatin has an anti-inflammatory effect on macrophages via upregulation of an atheroprotective transcription factor, Kruppel-like factor 2
    • Tuomisto TT, et al. Simvastatin has an anti-inflammatory effect on macrophages via upregulation of an atheroprotective transcription factor, Kruppel-like factor 2. Cardiovasc Res. 2008;78(1):175-184.
    • (2008) Cardiovasc Res , vol.78 , Issue.1 , pp. 175-184
    • Tuomisto, T.T.1
  • 27
    • 33344475402 scopus 로고    scopus 로고
    • Isoprenoids determine Th1/Th2 fate in pathogenic T cells, providing a mechanism of modulation of autoimmunity by atorvastatin
    • Dunn SE, et al. Isoprenoids determine Th1/Th2 fate in pathogenic T cells, providing a mechanism of modulation of autoimmunity by atorvastatin. J Exp Med. 2006;203(2):401-412.
    • (2006) J Exp Med , vol.203 , Issue.2 , pp. 401-412
    • Dunn, S.E.1
  • 28
    • 47249112564 scopus 로고    scopus 로고
    • KLF2-dependent, shear stress-induced expression of CD59: A novel cytoprotective mechanism against complement-mediated injury in the vasculature
    • Kinderlerer AR, et al. KLF2-dependent, shear stress-induced expression of CD59: a novel cytoprotective mechanism against complement-mediated injury in the vasculature. J Biol Chem. 2008;283(21):14636-14644.
    • (2008) J Biol Chem , vol.283 , Issue.21 , pp. 14636-14644
    • Kinderlerer, A.R.1
  • 29
    • 67349101678 scopus 로고    scopus 로고
    • Transcription factor ELF4 controls the proliferation and homing of CD8+ T cells via the Kruppel-like factors KLF4 and KLF2
    • Yamada T, Park CS, Mamonkin M, Lacorazza HD. Transcription factor ELF4 controls the proliferation and homing of CD8+ T cells via the Kruppel-like factors KLF4 and KLF2. Nat Immunol. 2009;10(6):618-626.
    • (2009) Nat Immunol , vol.10 , Issue.6 , pp. 618-626
    • Yamada, T.1    Park, C.S.2    Mamonkin, M.3    Lacorazza, H.D.4
  • 31
    • 33750374196 scopus 로고    scopus 로고
    • T-bet controls pathogenicity of CTLs in the heart by separable effects on migration and effector activity
    • Taqueti VR, et al. T-bet controls pathogenicity of CTLs in the heart by separable effects on migration and effector activity. J Immunol. 2006;177(9):5890-5901.
    • (2006) J Immunol , vol.177 , Issue.9 , pp. 5890-5901
    • Taqueti, V.R.1
  • 32
    • 33646354412 scopus 로고    scopus 로고
    • Statin therapy and autoimmune disease: From protein prenylation to immunomodulation
    • Greenwood J, Steinman L, Zamvil SS. Statin therapy and autoimmune disease: from protein prenylation to immunomodulation. Nat Rev Immunol. 2006;6(5):358-370.
    • (2006) Nat Rev Immunol , vol.6 , Issue.5 , pp. 358-370
    • Greenwood, J.1    Steinman, L.2    Zamvil, S.S.3
  • 34
    • 34250189127 scopus 로고    scopus 로고
    • Kruppel-like factor 2 controls T cell trafficking by activating L-selectin (CD62L) and sphingosine-1-phosphate receptor 1 transcription
    • Bai A, Hu H, Yeung M, Chen J. Kruppel-like factor 2 controls T cell trafficking by activating L-selectin (CD62L) and sphingosine-1-phosphate receptor 1 transcription. J Immunol. 2007;178(12):7632-7639. (Pubitemid 46898033)
    • (2007) Journal of Immunology , vol.178 , Issue.12 , pp. 7632-7639
    • Bai, A.1    Hu, H.2    Yeung, M.3    Chen, J.4
  • 36
    • 68249161292 scopus 로고    scopus 로고
    • How to be naive
    • Stein JV. How to be naive. Immunity. 2009;31(1):9-11.
    • (2009) Immunity , vol.31 , Issue.1 , pp. 9-11
    • Stein, J.V.1
  • 37
    • 53449090036 scopus 로고    scopus 로고
    • Amelioration of human allograft arterial injury by atorvastatin or simvastatin correlates with reduction of interferon-gamma production by infiltrating T cells
    • Yi T, et al. Amelioration of human allograft arterial injury by atorvastatin or simvastatin correlates with reduction of interferon-gamma production by infiltrating T cells. Transplantation. 2008;86(5):719-727.
    • (2008) Transplantation , vol.86 , Issue.5 , pp. 719-727
    • Yi, T.1
  • 39
    • 73649096734 scopus 로고    scopus 로고
    • Flow activation of AMP-activated protein kinase in vascular endothelium leads to Kruppel-like factor 2 expression
    • Young A, et al. Flow activation of AMP-activated protein kinase in vascular endothelium leads to Kruppel-like factor 2 expression. Arterioscler Thromb Vasc Biol. 2009;29(11):1902-1908.
    • (2009) Arterioscler Thromb Vasc Biol , vol.29 , Issue.11 , pp. 1902-1908
    • Young, A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.