Amelioration of human allograft arterial injury by atorvastatin or simvastatin correlates with reduction of interferon-γ production by infiltrating T cells

Transplantation

Volumn 86, Issue 5, 2008, Pages 719-727

  Yi, Tai ^a   Rao, Deepak A ^a   Tang, Paul C Y ^a   Wang, Yinong ^a   Cuchara, Lisa A ^a,b   Bothwell, Alfred L M ^a   Colangelo, Christopher M ^a   Tellides, George ^a   Pober, Jordan S ^a   Lorber, Marc I ^a,c  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b QUINNIPIAC UNIVERSITY   (United States)

^c NOVARTIS PHARMA AG   (Switzerland)

Author keywords

Allograft arteriopathy; HMG CoA reductase inhibitors; Interferon .; Statin; Transplant arteriosclerosis

Indexed keywords

ATORVASTATIN; GAMMA INTERFERON; HLA DR ANTIGEN; INTERLEUKIN 2; SIMVASTATIN; HEPTANOIC ACID DERIVATIVE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; PYRROLE DERIVATIVE;

ALLOIMMUNITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERIOSCLEROSIS; ARTERY GRAFT; ARTERY INJURY; ARTERY TRANSPLANTATION; ARTICLE; CD3+ T LYMPHOCYTE; CD4+ T LYMPHOCYTE; CELL INFILTRATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG BLOOD LEVEL; DRUG DOSE ESCALATION; DRUG DOSE INCREASE; DRUG EFFECT; GRAFT ARTERIOSCLEROSIS; GRAFT DYSFUNCTION; HUMAN; HUMAN CELL; HUMAN TISSUE; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; VASCULAR ENDOTHELIUM; ADULT; ALLOTRANSPLANTATION; ANIMAL; ARTERY; BIOSYNTHESIS; DRUG ANTAGONISM; FLOW CYTOMETRY; IMMUNOLOGY; LYMPHOCYTE TRANSFUSION; MONONUCLEAR CELL; MOUSE MUTANT; T LYMPHOCYTE; TRANSPLANTATION; XENOGRAFT;

ADULT; ANIMALS; ARTERIES; FLOW CYTOMETRY; HEPTANOIC ACIDS; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; INTERFERON TYPE II; LEUKOCYTES, MONONUCLEAR; LYMPHOCYTE TRANSFUSION; MICE; MICE, SCID; PYRROLES; SIMVASTATIN; T-LYMPHOCYTES; TRANSPLANTATION, HETEROLOGOUS; TRANSPLANTATION, HOMOLOGOUS;

EID: 53449090036     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/TP.0b013e318183eefa     Document Type: Article

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