Design, synthesis and biological evaluation of trans 2-(thiophen-2-yl)vinyl heteroaromatic iodides

Bioorganic and Medicinal Chemistry

Volumn 18, Issue 12, 2010, Pages 4516-4523

  Fortuna, Cosimo G ^a   Barresi, Vincenza ^a   Musumarra, Giuseppe ^a  

^a UNIVERSITY OF CATANIA   (Italy)

Author keywords

Antitumor compounds; Heterocycles; Molecular modeling; QSAR

Indexed keywords

ANTINEOPLASTIC AGENT; IODINE DERIVATIVE; NEW DRUG; TRANS 2 (THIOPHEN 2 YL)VINYL HETEROAROMATIC IODIDE DERIVATIVE; UNCLASSIFIED DRUG; IODIDE; THIOPHENE DERIVATIVE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL STRAIN LNCAP; CELL STRAIN MCF 7; CONTROLLED STUDY; DRUG DESIGN; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IN VITRO STUDY; MOLECULAR MODEL; PHYSICAL CHEMISTRY; PREDICTIVE VALIDITY; CHEMICAL STRUCTURE; CHEMISTRY; DRUG SCREENING; PRINCIPAL COMPONENT ANALYSIS; QUANTITATIVE STRUCTURE ACTIVITY RELATION; SYNTHESIS; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; DRUG DESIGN; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; IODIDES; MODELS, MOLECULAR; PRINCIPAL COMPONENT ANALYSIS; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; THIOPHENES;

PRUNUS DULCIS;

EID: 77953133197     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2010.04.060     Document Type: Article

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