3D-MEDNEs: An Alternative "In Silico" Technique for Chemical Research in Toxicology. 1. Prediction of Chemically Induced Agranulocytosis

Chemical Research in Toxicology

Volumn 16, Issue 10, 2003, Pages 1318-1327

  González Díaz, Humberto ^a   Marrero, Yovani ^a   Hernández, Ivan ^a   Bastida, Iyusmila ^a   Tenorio, Esvieta ^a   Nasco, Oslay ^a   Uriarte, Eugenio ^b   Castañedo, Nilo ^a   Cabrera, Miguel A ^a   Aguila, Edisleidy ^a   Marrero, Osmani ^a   Morales, Armando ^a   Pérez, Maikel ^a  

^a Central University of Las Villas   (Spain)

^b UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

AGRANULOCYTOSIS; ARTICLE; BLOOD TOXICITY; CHEMICAL ANALYSIS; COMPUTER MODEL; ENTROPY; FACTORIAL ANALYSIS; HYDROPHOBICITY; ISOMER; LINEAR SYSTEM; PARAMETER; PREDICTION; PROBABILITY; SEPARATION TECHNIQUE; STOCHASTIC MODEL; STOCHASTIC NEGENTROPY; TOXICOLOGICAL PARAMETERS; VALIDATION PROCESS;

AGRANULOCYTOSIS; ANIMALS; COMPUTER SIMULATION; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG TOXICITY; MARKOV CHAINS; MICE; MICE, INBRED BALB C; MODELS, CHEMICAL; MOLECULAR STRUCTURE; NEUTROPHILS; PHARMACEUTICAL PREPARATIONS; TIME FACTORS; TOXICOLOGY;

EID: 10444249026     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx0256432     Document Type: Article

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