Design, synthesis and in vitro antitumor activity of new trans 2-[2-(heteroaryl)vinyl]-1,3-dimethylimidazolium iodides

Bioorganic and Medicinal Chemistry

Volumn 12, Issue 7, 2004, Pages 1689-1695

  Ballistreri, Francesco P ^a   Barresi, Vincenza ^a   Benedetti, Paolo ^b   Caltabiano, Gianluigi ^a   Fortuna, Cosimo G ^a   Longo, Maria L ^a   Musumarra, Giuseppe ^a  

^a UNIVERSITY OF CATANIA   (Italy)

^b UNIVERSITY OF PERUGIA   (Italy)

Author keywords

Antitumor compds; Heterocycles; Molecular modelling; QSAR

Indexed keywords

2 [2 (5 BROMOFURAN 2 YL)VINYL] 1,3 DIMETHYLIMIDAZOLIUM IODIDE; 2 [2 (5 BROMOTHIOPHEN 2 YL)VINYL] 1,3 DIMETHYLIMIDAZOLIUM IODIDE; 2 [2 (5 METHYLFURAN 2 YL)VINYL] 1,3 DIMETHYLIMIDAZOLIUM IODIDE; 2 [2 (FURAN 2 YL)VINYL] 1,3 DIMETHYLIMIDAZOLIUM IODIDE; 2 [2 (N METHYLPYRROL 2 YL)VINYL] 1,3 DIMETHYLIMIDAZOLIUM IODIDE; 2 [2 (THIAZOL 2 YL)VINYL] 1,3 DIMETHYLIMIDAZOLIUM IODIDE; 2 [2 (THIOPHEN 2 YL)VINYL] 1,3 DIMETHYLIMIDAZOLIUM IODIDE; 2 [2 [5 (2 CHLOROPHENYL)FURAN 2 YL]VINYL] 1,3 DIMETHYLIMIDAZOLIUM IODIDE; 2 [2 [5 (4 BROMOPHENYL)FURAN 2 YL]VINYL] 1,3 DIMETHYLIMIDAZOLIUM IODIDE; ANTINEOPLASTIC AGENT; IMIDAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CARCINOMA; CARCINOMA CELL; CELL PROLIFERATION; CONTROLLED STUDY; CYTOTOXICITY; DRUG DESIGN; DRUG SYNTHESIS; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; MALE; PROSTATE CARCINOMA;

ANTINEOPLASTIC AGENTS; CELL DIVISION; CELL LINE, TUMOR; CELL SURVIVAL; DRUG DESIGN; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; IMIDAZOLES; IODIDES;

EID: 1542404531     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2004.01.018     Document Type: Article

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