Design and synthesis of trans 2-(furan-2-yl)vinyl heteroaromatic iodides with antitumour activity

Bioorganic and Medicinal Chemistry

Volumn 16, Issue 7, 2008, Pages 4150-4159

  Fortuna, Cosimo Gianluca ^a   Barresi, Vincenza ^a   Berellini, Giuliano ^b   Musumarra, Giuseppe ^a  

^a UNIVERSITY OF CATANIA   (Italy)

^b UNIVERSITY OF PERUGIA   (Italy)

Author keywords

Antitumour compounds; Heterocycles; Molecular modelling; QSAR

Indexed keywords

2 [2 (5 BROMOFURAN 2 YL)VINYL] 1 METHYLQUINOLINIUM IODIDE; 2 [2 [5 (2 CHLORO 5 TRIFLUOROMETHYLPHENYL)FURAN 2 YL]VINYL] 1 METHYLPYRIDINIUM IODIDE; 2 [2 [5 (2,4 DICHLOROPHENYL)FURAN 2 YL]VINYL] 1 METHYLPYRIDINIUM IODIDE; 2 [2 [5 (2,5 DICHLOROPHENYL)FURAN 2 YL]VINYL] 1 METHYLPYRIDINIUM IODIDE; 2 [2 [5 (2,5 DICHLOROPHENYL)FURAN 2 YL]VINYL] 1,3 DIMETHYLIMIDAZOLIUM IODIDE; 2 [2 [5 (3 CHLORO 4 METHOXYPHENYL)FURAN 2 YL]VINYL] 1 METHYLPYRIDINIUM IODIDE; 2 [2 [5 (3 CHLORO 4 METHOXYPHENYL)FURAN 2 YL]VINYL] 1 METHYLQUINOLINIUM IODIDE; 2 [2 [5 (3 CHLORO 4 METHOXYPHENYL)FURAN 2 YL]VINYL] 1,3 DIMETHYLIMIDAZOLIUM IODIDE; 2 [2 [5 (3 CHLOROPHENYL)FURAN 2 YL]VINYL] 1 METHYLQUINOLINIUM IODIDE; 2 [2 [5 (3 CHLOROPHENYL)FURAN 2 YL]VINYL] 1,3 DIMETHYLIMIDAZOLIUM IODIDE; 2 [2 [5 (3,4 DICHLOROPHENYL)FURAN 2 YL]VINYL] 1 METHYLPHYRIDINIUM IODIDE; 2 [2 [5 (4 CHLORO 2 NITROPHENYL)FURAN 2 YL]VINYL] 1 METHYLQUINOLINIUM IODIDE; 2 [2 [5 (4 CHLOROPHENYL)FURAN 2 YL]VINYL] 1 METHYLPYRIDINIUM IODIDE; 2 [2 [5 (4 CHLOROPHENYL)FURAN 2 YL]VINYL] 1 METHYLQUINOLINIUM IODIDE; 2 [2 [5 (4 CHLOROPHENYL)FURAN 2 YL]VINYL] 1,3 DIMETHYLIMIDAZOLIUM IODIDE; IODINE DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CARCINOMA; CANCER CELL CULTURE; DRUG DESIGN; DRUG SYNTHESIS; HUMAN; HUMAN CELL; MOLECULAR MODEL; PHYSICAL CHEMISTRY; VOLSURF PLUS;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL SURVIVAL; DRUG DESIGN; FURANS; HUMANS; IODIDES; MODELS, MOLECULAR; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP; VINYL COMPOUNDS;

EID: 41649106660     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2007.12.042     Document Type: Article

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