The SH3 domain of postsynaptic density 95 mediates inflammatory pain through phosphatidylinositol-3-kinase recruitment

EMBO Reports

Volumn 11, Issue 6, 2010, Pages 473-478

  Arbuckle, Margaret I ^a   Komiyama, Noboru H ^b   Delaney, Ada ^a   Coba, Marcelo ^a   Garry, Emer M ^a   Rosie, Roberta ^a   Allchorne, Andrew J ^a   Forsyth, Lynsey H ^a   Bence, Matthew ^a   Carlisle, Holly J ^c   O'Dell, Thomas J ^c   Mitchell, Rory ^a   Fleetwood Walker, Susan M ^a   Grant, Seth G N ^b  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Inflammation; Nociception; PSD95; SH3 domain

Indexed keywords

PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE C2ALPHA; POLYPROLINE; POSTSYNAPTIC DENSITY PROTEIN 95; PROLINE DERIVATIVE; PROTEIN SH3; UNCLASSIFIED DRUG; WORTMANNIN;

AMINO ACID SUBSTITUTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING SITE; CONTROLLED STUDY; FEMALE; INFLAMMATION; MALE; MOUSE; NERVE CELL PLASTICITY; NEUROPATHOLOGY; NONHUMAN; PAIN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN FUNCTION; SENSITIZATION; SIGNAL TRANSDUCTION; WILD TYPE; X RAY CRYSTALLOGRAPHY;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; HIPPOCAMPUS; INFLAMMATION; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MEMBRANE PROTEINS; MICE; NEURONAL PLASTICITY; PAIN; POINT MUTATION; PROTEIN BINDING; SRC HOMOLOGY DOMAINS; STRUCTURE-ACTIVITY RELATIONSHIP; SYNAPSES;

MUS;

EID: 77953123284     PISSN: 1469221X     EISSN: 14693178     Source Type: Journal    
DOI: 10.1038/embor.2010.63     Document Type: Article

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