The exceptional properties of 9-methyl-β-carboline: Stimulation, protection and regeneration of dopaminergic neurons coupled with anti-inflammatory effects

Journal of Neurochemistry

Volumn 113, Issue 6, 2010, Pages 1659-1675

  Polanski, Witold ^a   Enzensperger, Christoph ^b   Reichmann, Heinz ^a   Gille, Gabriele ^a  

^a DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

^b FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

Author keywords

9 methyl carboline; Dopaminergic neurons; Inflammation; Neuroprotection; Neuroregeneration

Indexed keywords

4 AMINO 7 TERT BUTYL 5 (4 CHLOROPHENYL)PYRAZOLO[3,4 D]PYRIMIDINE; 9 METHYL BETA CARBOLINE; AG 18; AROMATIC LEVO AMINO ACID DECARBOXYLASE; BETA CARBOLINE; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; CYTOKINE; CYTOKINE RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; FIBROBLAST GROWTH FACTOR RECEPTOR; FOCAL ADHESION KINASE; GENISTEIN; LIPOPOLYSACCHARIDE; NERVE CELL ADHESION MOLECULE; PROTEIN KINASE C; ROTENONE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GATA 2; TRANSCRIPTION FACTOR GATA 3; TYROSINE 3 MONOOXYGENASE; TYRPHOSTIN; UNCLASSIFIED DRUG; VANOXERINE;

ACUTE TOXICITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL CULTURE; CELL PROLIFERATION; CHRONIC TOXICITY; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; GENE SEQUENCE; IMMUNOCOMPETENT CELL; MICROGLIA; MOUSE; NERVE CELL; NERVE CELL STIMULATION; NERVE FIBER GROWTH; NERVE REGENERATION; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; NUCLEOTIDE SEQUENCE; PARKINSON DISEASE; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS; TYROSINE HYDROXYLASE IMMUNOREACTIVE NEURONS;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CARBOLINES; CELLS, CULTURED; CYTOKINES; DEOXYURIDINE; DOPA DECARBOXYLASE; DOPAMINE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; EMBRYO, MAMMALIAN; FEMALE; GENE EXPRESSION REGULATION; L-LACTATE DEHYDROGENASE; LIPOPOLYSACCHARIDES; MESENCEPHALON; MICE; MICE, INBRED C57BL; NEURONS; NEUROPROTECTIVE AGENTS; PIPERAZINES; PREGNANCY; RECEPTORS, CYTOKINE; REGENERATION; RNA, MESSENGER; STATISTICS, NONPARAMETRIC; TYROSINE 3-MONOOXYGENASE;

PARKINSONIA;

EID: 77953112679     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2010.06725.x     Document Type: Article

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