A lysine accumulation phenotype of Sclpk2Δ mutant yeast is rescued by Solanum tuberosum inositol phosphate multikinase

Biochemical Journal

Volumn 403, Issue 3, 2007, Pages 381-389

  Caddick, Samuel E K ^a   Harrison, Christopher J ^a   Stavridou, Ioanna ^a   Johnson, Sue ^a   Brearley, Charles A ^a  

^a UNIVERSITY OF EAST ANGLIA   (United Kingdom)

Author keywords

Arginine; Inositol phosphate multikinase (IPMK); Lysine; Saccharomyces cerevisiae; Solanum tuberosum

Indexed keywords

ARGININE; BIOSYNTHETIC GENES; INOSITOL PHOSPHATES; INOSITOL POLYPHOSPHATE KINASE; LYSINE; MUTANTS; SOLANUM TUBEROSUM;

AMINO ACIDS; BIOSYNTHESIS; ENZYME KINETICS; MUTAGENESIS; PHOSPHATES; TRANSCRIPTION; TRANSCRIPTION FACTORS;

YEAST;

ACETYLORNITHINE AMINOTRANSFERASE; AMINOTRANSFERASE; ARGININE; INOSITOL PHOSPHATE; INOSITOL PHOSPHATE MULTIKINASE; LYSINE; ORNITHINE CARBAMOYLTRANSFERASE; SACCHAROMYCES CEREVISIAE PROTEIN; UNCLASSIFIED DRUG; ARG82 PROTEIN, S CEREVISIAE; INOSITOL POLYPHOSPHATE MULTIKINASE; ORNITHINE; PHOSPHOTRANSFERASE; RECOMBINANT PROTEIN;

AMINO ACID SEQUENCE; ARTICLE; DNA SYNTHESIS; GENETIC TRANSCRIPTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; IN VITRO STUDY; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; POTATO; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ISOLATION; SACCHAROMYCES CEREVISIAE; YEAST; BIOSYNTHESIS; ENZYMOLOGY; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; MOLECULAR CLONING; MOLECULAR GENETICS; PHYSIOLOGY; SEQUENCE ALIGNMENT;

SACCHAROMYCES CEREVISIAE; SOLANUM TUBEROSUM;

AMINO ACID SEQUENCE; ARGININE; CLONING, MOLECULAR; LYSINE; MOLECULAR SEQUENCE DATA; ORNITHINE; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); RECOMBINANT PROTEINS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SEQUENCE ALIGNMENT; SOLANUM TUBEROSUM;

EID: 34247867964     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20061772     Document Type: Article

References (36)

1. Shears, S. B. (2004) How versatile are inositol phosphate kinases? Biochem. J. 377, 265-280
2. Stevenson-Paulik, J., Bastidas, R. J., Chiou, S. T., Frye, R. A. and York, J. D. (2005) Generation of phytate-free seeds in Arabidopsis through disruption of inositol polyphosphate kinases. Proc. Natl. Acad. Sci. U.S.A. 102, 12612-12617
3. Saiardi, A., Caffrey, J. J., Snyder, S. H. and Shears, S. B. (2000) Inositol polyphosphate multikinase (ArgRIII) determines nuclear mRNA export in Saccharomyces cerevisiae. FEBS Lett. 468, 28-32
4. Miller, A. L., Suntharalingam, M., Johnson, S. L., Audhya, A., Emr, S. D. and Wente, S. R. (2004) Cytoplasmic inositol hexakisphosphate production is sufficient for mediating the Gle1-mRNA export pathway. J. Biol. Chem. 279, 51022-51032
5. Dubois, E., Dewaste, V., Erneux, C. and Messenguy, F. (2000) Inositol polyphosphate kinase activity of Arg82/ArgRIII is not required for the regulation of the arginine metabolism in yeast. FEBS Lett. 486, 300-304
6. el Alami, M., Messenguy, F., Scherens, B. and Dubois, E. (2003) Arg82p is a bifunctional protein whose inositol polyphosphate kinase activity is essential for nitrogen and PHO gene expression but not for Mcm1p chaperoning in yeast. Mol. Microbiol. 49, 457-468
7. Xia, H., Brearley, C. A., Elge, S., Kaplan, B., Fromm, H. and Mueller-Roeber, B. (2003) Arabidopsis inositol polyphosphate 6-/3-kinase is a nuclear protein that complements a yeast mutant lacking a functional ArgR-Mcm1 transcription complex. Plant Cell 15, 1-16
8. Dubois, E. and Messenguy, F. (1994) Pleiotropic function of ArgRIIIp (Arg82p), one of the regulators of arginine metabolism in Saccharomyces cerevisiae. Role in expression of cell-type-specific genes. Mol. Gen. Genet. 243, 315-324
9. Qiu, H. F., Dubois, E., Broen, P. and Messenguy, F. (1990) Functional analysis of ARGRI and ARGRIII regulatory proteins involved in the regulation of arginine metabolism in Saccharomyces cerevisiae. Mol. Gen. Genet. 222, 192-200
10. Shears, S. B. (2000) Transcriptional regulation: a new dominion for inositol phosphate signaling? BioEssays 22, 786-789
11. Zhang, T., Caffrey, J. J. and Shears, S. B. (2001) The transcriptional regulator, Arg82, is a hybrid kinase with both monophosphoinositol and diphosphoinositol polyphosphate synthase activity. FEBS Lett. 494, 208-212
12. Odom, A. R., Stahlberg, A., Wente, S. R. and York, J. D. (2000) A role for nuclear inositol 1,4,5-trisphosphate kinase in transcriptional control. Science 287, 2026-2029
13. Seeds, A. M., Bastidas, R. J. and York, J. D. (2005) Molecular definition of a novel inositol polyphosphate metabolic pathway initiated by inositol 1,4,5-trisphosphate 3-kinase activity in Saccharomyces cerevisiae. J. Biol. Chem. 280, 27654-27661
14. Resnick, A. C., Snowman, A. M., Kang, B. N., Hurt, K. J., Snyder, S. H. and Saiardi, A. (2005) Inositol polyphosphate multikinase is a nuclear PI3-kinase with transcriptional regulatory activity. Proc. Natl. Acad. Sci. U.S.A. 102, 12783-12788
15. Stevenson-Paulik, J., Odom, A. R. and York, J. D. (2002) Molecular and biochemical characterization of two plant inositol polyphosphate 6-/3-/5-kinases. J. Biol. Chem. 277, 42711-42718
16. Sweetman, D., Johnson, S., Caddick, S. E., Hanke, D. E. and Brearley, C. A. (2006) Characterization of an Arabidopsis inositol 1,3,4,5,6- pentakisphosphate 2-kinase (AtIPKI). Biochem. J. 394, 95-103
17. van Eijk, H. M., Rooyakkers, D. R., Soeters, P. B. and Deutz, N. E. (1999) Determination of amino acid isotope enrichment using liquid chromatography-mass spectrometry. Anal. Biochem. 271, 8-17
18. Nalaskowski, M. M., Deschermeier, C., Fanick, W. and Mayr, G. W. (2002) The human homologue of yeast ArgRIII protein is an inositol phosphate multikinase with predominantly nuclear localization. Biochem. J. 366, 549-556
19. Saiardi, A., Nagata, E., Luo, H. R., Sawa, A., Luo, X., Snowman, A. M. and Snyder, S. H. (2001) Mammalian inositol polyphosphate multikinase synthesizes inositol 1,4,5-trisphosphate and an inositol pyrophosphate. Proc. Natl. Acad. Sci. U.S.A. 98, 2306-2311
20. Saiardi, A., Nagata, E., Luo, H. R., Snowman, A. M. and Snyder, S. H. (2001) Identification and characterization of a novel inositol hexakisphosphate kinase. J. Biol. Chem. 276, 39179-39185
21. Schell, M. J., Letcher, A. J., Brearley, C. A., Biber, J., Murer, H. and Irvine, R. F. (1999) PiUS (Pi uptake stimulator) is an inositol hexakisphosphate kinase. FEBS Lett. 461, 169-172
22. York, J. D., Guo, S., Odom, A. R., Spiegelberg, B. D. and Stolz, L. E. (2001) An expanded view Of inositol signalling. Adv. Enzyme Regul. 41, 57-71
23. Bechet, J., Greenson, M. and Wiame, J. M. (1970) Mutations affecting the repressibility of arginine biosynthetic enzymes in Saccharomyces cerevisiae. Eur. J. Biochem. 12, 31-39
24. Messenguy, F. and Dubois, E. (1993) Genetic evidence for a role for MCM1 in the regulation of arginine metabolism in Saccharomyces cerevisiae. Mol. Cell Biol. 13, 2586-2592
25. Dubois, E., Scherens, B., Vierendeels, F., Ho, M. M. W., Messenguy, F. and Shears, S. B. (2002) In Saccharomyces cerevisiae, the inositol polyphosphate kinase activity of Kcs1p is required for resistance to salt stress, cell wall integrity, and vacuolar morphogenesis J. Biol. Chem. 277, 23755-23763
26. York, J. D., Odom, A. R., Murphy, R., Ives, E. B. and Wente, S. R. (1999) A phospholipase C-dependent inositol polyphosphate kinase pathway required for efficient messenger RNA export. Science 285, 96-100
27. Steger, D. J., Haswell, E. S., Miller, A. L., Wente, S. R. and O'Shea, E. K. (2003) Regulation of chromatin remodeling by inositol polyphosphates. Science 299, 114-116
28. Holmes, W. and Jogl, G. (2006) Crystal structure of inositol phosphate multikinase 2 and implications for substrate specificity. J. Biol. Chem. 281, 38109-38116
29. Gonzalez, B., Schell, M. J., Letcher, A. J., Veprintsev, D. B., Irvine, R. F. and Williams, R. L. (2004) Structure of a human inositol 1,4,5-trisphosphate 3-kinase: substrate binding reveals why it is not a phosphoinositide 3-kinase. Mol. Cell 15, 689-701
30. York, J. D. (2006) Regulation of nuclear processes by inositol polyphosphates. Biochim. Biophys. Acta 1761, 552-559
31. Pauwels, K., Abadjieva, A., Hilven, P., Stankiewicz, A. and Crabeel, M. (2003) The N-acetylglutamate synthase/N-acetylglutamate kinase metabolon of Saccharomyces cerevisiae allows co-ordinated feedback regulation of the first two steps in arginine biosynthesis. Eur. J. Biochem. 270, 1014-1024
32. Zabriskie, T. M. and Jackson, M. D. (2000) Lysine biosynthesis and metabolism in fungi Nat. Prod. Rep. 17, 85-97
33. Nishida, H. and Nishiyama, M. (2000) What is characteristic of fungal lysine synthesis through the α-aminoadipate pathway? J. Mol. Evol. 51, 299-302
34. Feller, A., Ramos, F., Pierard, A. and Dubois, E. (1999) In Saccharomyces cerevisae, feedback inhibition of homocitrate synthase isoenzymes by lysine modulates the activation of LYS gene expression by Lys14p. Eur. J. Biochem. 261, 163-170
35. Ramos, F., Dubois, E. and Pierard, A. (1988) Control of enzyme synthesis in the lysine biosynthetic pathway of Saccharomyces cerevisiae. Evidence for a regulatory role of gene LYS14. Eur. J. Biochem. 171, 171-176
36. Gasent-Ramirez, J. M. and Benitez, T. (1997) Lysine-overproducing mutants of Saccharomyces cerevisiae baker's yeast isolated in continuous culture. Appl. Environ. Microbiol. 63, 4800-4806