A rapid and scalable method for selecting recombinant mouse monoclonal antibodies

BMC Biology

Volumn 8, Issue , 2010, Pages

  Crosnier, Cécile ^a   Staudt, Nicole ^a   Wright, Gavin J ^a  

^a WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DANIO RERIO; MAMMALIA; MUS;

IMMUNOGLOBULIN G; MONOCLONAL ANTIBODY; RECOMBINANT PROTEIN;

ANIMAL; ARTICLE; BAGG ALBINO MOUSE; CELL LINE; GENE EXPRESSION; GENETICS; HUMAN; HYBRIDOMA; IMMUNOLOGY; ISOLATION AND PURIFICATION; MALE; METHODOLOGY; MOLECULAR CLONING; MOUSE; PRENATAL DEVELOPMENT; TUMOR CELL LINE; ZEBRA FISH;

ANIMALS; ANTIBODIES, MONOCLONAL; CELL LINE; CELL LINE, TUMOR; CLONING, MOLECULAR; GENE EXPRESSION; HUMANS; HYBRIDOMAS; IMMUNOGLOBULIN G; MALE; MICE; MICE, INBRED BALB C; RECOMBINANT PROTEINS; ZEBRAFISH;

EID: 77952997277     PISSN: None     EISSN: 17417007     Source Type: Journal    
DOI: 10.1186/1741-7007-8-76     Document Type: Article

References (33)

1. Goldman RD. Antibodies: indispensable tools for biomedical research. Trends Biochem Sci 2000, 25:593-595. 10.1016/S0968-0004(00)01725-4, 11116184.
2. Taussig MJ, Stoevesandt O, Borrebaeck CA, Bradbury AR, Cahill D, Cambillau C, Ade D, Dubel S, Eichler J, Frank R, et al. ProteomeBinders: planning a European resource of affinity reagents for analysis of the human proteome. Nat Methods 2007, 4:13-17. 10.1038/nmeth0107-13, 17195019.
3. Beste G, Schmidt FS, Stibora T, Skerra A. Small antibody-like proteins with prescribed ligand specificities derived from the lipocalin fold. Proc Natl Acad Sci USA 1999, 96:1898-1903. 26708, 10051566, 10.1073/pnas.96.5.1898.
4. Binz HK, Amstutz P, Kohl A, Stumpp MT, Briand C, Forrer P, Grutter MG, Pluckthun A. High-affinity binders selected from designed ankyrin repeat protein libraries. Nat Biotechnol 2004, 22:575-582. 10.1038/nbt962, 15097997.
5. Nord K, Gunneriusson E, Ringdahl J, Stahl S, Uhlen M, Nygren PA. Binding proteins selected from combinatorial libraries of an alpha-helical bacterial receptor domain. Nat Biotechnol 1997, 15:772-777. 10.1038/nbt0897-772, 9255793.
6. Tuerk C, Gold L. Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase. Science 1990, 249:505-510. 10.1126/science.2200121, 2200121.
7. Dresser DW. Immunisation of Experimental Animals. 1986, Oxford: Blackwell Scientific.
8. De Masi F, Chiarella P, Wilhelm H, Massimi M, Bullard B, Ansorge W, Sawyer A. High throughput production of mouse monoclonal antibodies using antigen microarrays. Proteomics 2005, 5:4070-4081. 10.1002/pmic.200401279, 16254927.
9. Deflorian G, Cinquanta M, Beretta C, Venuto A, Santoriello C, Baldessari D, Pezzimenti F, Aliprandi M, Mione M, de Marco A. Monoclonal antibodies isolated by large-scale screening are suitable for labeling adult zebrafish (Danio rerio) tissues and cell structures. J Immunol Methods 2009, 346:9-17. 10.1016/j.jim.2009.04.012, 19410577.
10. Driever W, Stemple D, Schier A, Solnica-Krezel L. Zebrafish: genetic tools for studying vertebrate development. Trends Genet 1994, 10:152-159. 10.1016/0168-9525(94)90091-4, 8036717.
11. Haffter P, Nusslein-Volhard C. Large scale genetics in a small vertebrate, the zebrafish. Int J Dev Biol 1996, 40:221-227.
12. Lieschke GJ, Currie PD. Animal models of human disease: zebrafish swim into view. Nat Rev Genet 2007, 8:353-367. 10.1038/nrg2091, 17440532.
13. Driever W, Solnica-Krezel L, Schier AF, Neuhauss SC, Malicki J, Stemple DL, Stainier DY, Zwartkruis F, Abdelilah S, Rangini Z, Belak J, Boggs C. A genetic screen for mutations affecting embryogenesis in zebrafish. Development 1996, 123:37-46.
14. Solnica-Krezel L, Stemple DL, Driever W. Transparent things: cell fates and cell movements during early embryogenesis of zebrafish. Bioessays 1995, 17:931-939. 10.1002/bies.950171106, 8526887.
15. Nasevicius A, Ekker SC. Effective targeted gene 'knockdown' in zebrafish. Nat Genet 2000, 26:216-220. 10.1038/79951, 11017081.
16. Wienholds E, Schulte-Merker S, Walderich B, Plasterk RH. Target-selected inactivation of the zebrafish rag1 gene. Science 2002, 297:99-102. 10.1126/science.1071762, 12098699.
17. Cheng KC. Views on four key questions about zebrafish research. Zebrafish 2008, 5:9-24. 10.1089/zeb.2008.9996, 18399790.
18. Crosnier C, Vargesson N, Gschmeissner S, Ariza-McNaughton L, Morrison A, Lewis J. Delta-Notch signalling controls commitment to a secretory fate in the zebrafish intestine. Development 2005, 132:1093-1104. 10.1242/dev.01644, 15689380.
19. Trevarrow B, Marks DL, Kimmel CB. Organization of hindbrain segments in the zebrafish embryo. Neuron 1990, 4:669-679. 10.1016/0896-6273(90)90194-K, 2344406.
20. Traver D, Paw BH, Poss KD, Penberthy WT, Lin S, Zon LI. Transplantation and in vivo imaging of multilineage engraftment in zebrafish bloodless mutants. Nat Immunol 2003, 4:1238-1246. 10.1038/ni1007, 14608381.
21. Bushell KM, Sollner C, Schuster-Boeckler B, Bateman A, Wright GJ. Large-scale screening for novel low-affinity extracellular protein interactions. Genome Res 2008, 18:622-630. 2279249, 18296487, 10.1101/gr.7187808.
22. Sollner C, Wright GJ. A cell surface interaction network of neural leucine-rich repeat receptors. Genome Biol 2009, 10:R99. 2768988, 19765300, 10.1186/gb-2009-10-9-r99.
23. Durocher Y, Perret S, Kamen A. High-level and high-throughput recombinant protein production by transient transfection of suspension-growing human 293-EBNA1 cells. Nucleic Acids Res 2002, 30:E9. 99848, 11788735, 10.1093/nar/30.2.e9.
24. Kimmel CB, Ballard WW, Kimmel SR, Ullmann B, Schilling TF. Stages of embryonic development of the zebrafish. Dev Dyn 1995, 203:253-310.
25. Thisse C, Thisse B. High-resolution in situ hybridization to whole-mount zebrafish embryos. Nat Protoc 2008, 3:59-69. 10.1038/nprot.2007.514, 18193022.
26. Krebber A, Bornhauser S, Burmester J, Honegger A, Willuda J, Bosshard HR, Pluckthun A. Reliable cloning of functional antibody variable domains from hybridomas and spleen cell repertoires employing a reengineered phage display system. J Immunol Methods 1997, 201:35-55. 10.1016/S0022-1759(96)00208-6, 9032408.
27. Cotner T, Eisen HN. The natural abundance of lambda2-light chains in inbred mice. J Exp Med 1978, 148:1388-1399. 2185043, 102727, 10.1084/jem.148.5.1388.
28. Liu ZQ, Wu AF, Wu TT. Short gene inversion involving two adjacent heavy chain joining minigenes and one heavy chain diversity minigene in the nonsecretor Sp2/0-Ag14 myeloma cell line. Nucleic Acids Res 1987, 15:4688. 340890, 3108858, 10.1093/nar/15.11.4688.
29. Strohal R, Kroemer G, Wick G, Kofler R. Complete variable region sequence of a nonfunctionally rearranged kappa light chain transcribed in the nonsecretor P3-X63-Ag8.653 myeloma cell line. Nucleic Acids Res 1987, 15:2771. 340683, 3104882, 10.1093/nar/15.6.2771.
30. Kilpatrick KE, Wring SA, Walker DH, Macklin MD, Payne JA, Su JL, Champion BR, Caterson B, McIntyre GD. Rapid development of affinity matured monoclonal antibodies using RIMMS. Hybridoma 1997, 16:381-389. 10.1089/hyb.1997.16.381, 9309429.
31. Jin A, Ozawa T, Tajiri K, Obata T, Kondo S, Kinoshita K, Kadowaki S, Takahashi K, Sugiyama T, Kishi H, Muraguchi A. A rapid and efficient single-cell manipulation method for screening antigen-specific antibody-secreting cells from human peripheral blood. Nat Med 2009, 15:1088-1092. 10.1038/nm.1966, 19684583.
32. Smith K, Garman L, Wrammert J, Zheng NY, Capra JD, Ahmed R, Wilson PC. Rapid generation of fully human monoclonal antibodies specific to a vaccinating antigen. Nat Protoc 2009, 4:372-384. 2750034, 19247287, 10.1038/nprot.2009.3.
33. Backliwal G, Hildinger M, Chenuet S, Wulhfard S, De Jesus M, Wurm FM. Rational vector design and multi-pathway modulation of HEK 293E cells yield recombinant antibody titers exceeding 1 g/l by transient transfection under serum-free conditions. Nucleic Acids Res 2008, 36:e96. 2528171, 18617574, 10.1093/nar/gkn423.