-
1
-
-
85013312416
-
Tumor angiogenesis: Therapeutic implications
-
Folkman J. Tumor angiogenesis: therapeutic implications. N Engl J Med 1971; 285: 1182-6.
-
(1971)
N Engl J Med
, vol.285
, pp. 1182-1186
-
-
Folkman, J.1
-
2
-
-
20544455330
-
Bevacizumab (Avastin), a humanized anti-VEGF monoclonal antibody for cancer therapy
-
Ferrara N, Hillan KJ, Novotny W. Bevacizumab (Avastin), a humanized anti-VEGF monoclonal antibody for cancer therapy. Biochem Biophys Res Commun 2005; 333(2): 328-35.
-
(2005)
Biochem Biophys Res Commun
, vol.333
, Issue.2
, pp. 328-335
-
-
Ferrara, N.1
Hillan, K.J.2
Novotny, W.3
-
3
-
-
18344390418
-
ERBB receptors and cancer: The complexity of targeted inhibitors
-
Hynes NE, Lane HA. ERBB receptors and cancer: the complexity of targeted inhibitors. Nat Rev Cancer 2005; 5: 341-54.
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 341-354
-
-
Hynes, N.E.1
Lane, H.A.2
-
4
-
-
28044433677
-
Epidermal growth factor receptor and angiogenesis: Opportunities for combined anticancer strategies
-
van Cruijsen H, Giaccone G, Hoekman K. Epidermal growth factor receptor and angiogenesis: opportunities for combined anticancer strategies. Int J Cancer 2005; 117(6): 883-8.
-
(2005)
Int J Cancer
, vol.117
, Issue.6
, pp. 883-888
-
-
van Cruijsen, H.1
Giaccone, G.2
Hoekman, K.3
-
5
-
-
38449087414
-
The role of the EGFR signaling in tumor microenvironment
-
De Luca A, Carotenuto A, Rachiglio A, et al. The role of the EGFR signaling in tumor microenvironment. J Cell Physiol 2008; 214: 559-67.
-
(2008)
J Cell Physiol
, vol.214
, pp. 559-567
-
-
de Luca, A.1
Carotenuto, A.2
Rachiglio, A.3
-
6
-
-
33644529055
-
ErbB2 increases vascular endothelial growth factor protein synthesis via activation of mammalian target of rapamycin/p70S6K leading to increased angiogenesis and spontaneous metastasis of human breast cancer cells
-
Klos K, Wyszomierski S, Sun M, et al. ErbB2 increases vascular endothelial growth factor protein synthesis via activation of mammalian target of rapamycin/p70S6K leading to increased angiogenesis and spontaneous metastasis of human breast cancer cells. Cancer Res 2006; 66: 2028-37.
-
(2006)
Cancer Res
, vol.66
, pp. 2028-2037
-
-
Klos, K.1
Wyszomierski, S.2
Sun, M.3
-
7
-
-
71549121010
-
The EGFR inhibitor gefitinib suppresses recruitment of pericytes and bone marrow-derived perivascular cells into tumor vessels
-
Iivanainen E, Lauttia S, Zhang N, et al. The EGFR inhibitor gefitinib suppresses recruitment of pericytes and bone marrow-derived perivascular cells into tumor vessels. Microvasc Res 2009; 78: 278-85.
-
(2009)
Microvasc Res
, vol.78
, pp. 278-285
-
-
Iivanainen, E.1
Lauttia, S.2
Zhang, N.3
-
8
-
-
0036831559
-
Vascular and haematopoietic stem cells: Novel targets for anti-angiogenesis therapy?
-
Rafii S, Lyden D, Benezra R, et al. Vascular and haematopoietic stem cells: novel targets for anti-angiogenesis therapy? Nat Rev Cancer 2002; 2: 826-35.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 826-835
-
-
Rafii, S.1
Lyden, D.2
Benezra, R.3
-
9
-
-
30744479430
-
Angiogenesis in life, disease and medicine
-
Carmeliet P. Angiogenesis in life, disease and medicine. Nature 2005; 438: 932-6.
-
(2005)
Nature
, vol.438
, pp. 932-936
-
-
Carmeliet, P.1
-
10
-
-
27644557532
-
The role of pericytes in blood-vessel formation and maintenance
-
Bergers G, Song S. The role of pericytes in blood-vessel formation and maintenance. Neuro Oncol 2005; 7: 452-64.
-
(2005)
Neuro Oncol
, vol.7
, pp. 452-464
-
-
Bergers, G.1
Song, S.2
-
11
-
-
33751551658
-
The bone marrow constitutes a reservoir of pericyte progenitors
-
Lamagna C, Bergers G. The bone marrow constitutes a reservoir of pericyte progenitors. J Leukoc Biol 2006; 80: 677-81.
-
(2006)
J Leukoc Biol
, vol.80
, pp. 677-681
-
-
Lamagna, C.1
Bergers, G.2
-
12
-
-
0037149539
-
Tumour biology: Herceptin acts as an anti-angiogenic cocktail
-
Izumi Y, Xu L, di Tomaso E, et al. Tumour biology: herceptin acts as an anti-angiogenic cocktail. Nature 2002; 416: 279-80.
-
(2002)
Nature
, vol.416
, pp. 279-280
-
-
Izumi, Y.1
Xu, L.2
di Tomaso, E.3
-
13
-
-
11244258222
-
Epidermal growth factor receptor inhibition strategies in oncology
-
Harari PM. Epidermal growth factor receptor inhibition strategies in oncology. Endocr Relat Cancer 2004; 11: 689-708.
-
(2004)
Endocr Relat Cancer
, vol.11
, pp. 689-708
-
-
Harari, P.M.1
-
14
-
-
0034600849
-
The ErbB signaling network: Receptor heterodimerization in development and cancer
-
Olayioye MA, Neve RM, Lane HA, et al. The ErbB signaling network: receptor heterodimerization in development and cancer. EMBO J 2000; 19: 3159-67.
-
(2000)
EMBO J
, vol.19
, pp. 3159-3167
-
-
Olayioye, M.A.1
Neve, R.M.2
Lane, H.A.3
-
15
-
-
0030953468
-
Activation of HER4 by heparin binding EGF-like growth factor stimulates chemotaxis but not proliferation
-
Elenius K, Paul S, Allison G, et al. Activation of HER4 by heparin binding EGF-like growth factor stimulates chemotaxis but not proliferation. EMBO J 1997; 16: 1268-78.
-
(1997)
EMBO J
, vol.16
, pp. 1268-1278
-
-
Elenius, K.1
Paul, S.2
Allison, G.3
-
18
-
-
0037429649
-
Neuregulins: Functions, forms, and signaling strategies
-
Falls DL. Neuregulins: functions, forms, and signaling strategies. Exp Cell Res 2003; 284: 14-30.
-
(2003)
Exp Cell Res
, vol.284
, pp. 14-30
-
-
Falls, D.L.1
-
19
-
-
0027240384
-
Heparin-binding EGF-like growth factor stimulation of smooth muscle cell migration: Dependence on interactions with cell surface heparan sulfate
-
Higashiyama S, Abraham JA, Klagsbrun M. Heparin-binding EGF-like growth factor stimulation of smooth muscle cell migration: dependence on interactions with cell surface heparan sulfate. J Cell Biol 1993; 122: 933-40.
-
(1993)
J Cell Biol
, vol.122
, pp. 933-940
-
-
Higashiyama, S.1
Abraham, J.A.2
Klagsbrun, M.3
-
20
-
-
0035796401
-
N-arginine dibasic convertase is a specific receptor for heparin-binding EGF-like growth factor that mediates cell migration
-
Nishi E, Prat A, Hospital V, et al. N-arginine dibasic convertase is a specific receptor for heparin-binding EGF-like growth factor that mediates cell migration. EMBO J 2001; 20: 3342-50.
-
(2001)
EMBO J
, vol.20
, pp. 3342-3350
-
-
Nishi, E.1
Prat, A.2
Hospital, V.3
-
21
-
-
34547191653
-
Intra- and extracellular signaling by endothelial neuregulin-1
-
Iivanainen E, Paatero I, Heikkinen S, et al. Intra- and extracellular signaling by endothelial neuregulin-1. Exp Cell Res 2007; 313: 2896-909.
-
(2007)
Exp Cell Res
, vol.313
, pp. 2896-2909
-
-
Iivanainen, E.1
Paatero, I.2
Heikkinen, S.3
-
22
-
-
0037815413
-
Back signaling by the Nrg-1 intracellular domain
-
Bao J, Wolpowitz D, Role LW, et al. Back signaling by the Nrg-1 intracellular domain. J Cell Biol 2003; 161: 1133-41.
-
(2003)
J Cell Biol
, vol.161
, pp. 1133-1141
-
-
Bao, J.1
Wolpowitz, D.2
Role, L.W.3
-
23
-
-
0026747170
-
Expression cloning of a diphtheria toxin receptor: Identity with a heparin-binding EGF-like growth factor precursor
-
Naglich JG, Metherall JE, Russell DW, et al. Expression cloning of a diphtheria toxin receptor: identity with a heparin-binding EGF-like growth factor precursor. Cell 1992; 69: 1051-61.
-
(1992)
Cell
, vol.69
, pp. 1051-1061
-
-
Naglich, J.G.1
Metherall, J.E.2
Russell, D.W.3
-
24
-
-
0028284810
-
Heparin-binding EGF-like growth factor, which acts as the diphtheria toxin receptor, forms a complex with membrane protein DRAP27/CD9, which upregulates functional receptors and diphtheria toxin sensitivity
-
Iwamoto R, Higashiyama S, Mitamura T, et al. Heparin-binding EGF-like growth factor, which acts as the diphtheria toxin receptor, forms a complex with membrane protein DRAP27/CD9, which upregulates functional receptors and diphtheria toxin sensitivity. EMBO J 1994; 13: 2322-30.
-
(1994)
EMBO J
, vol.13
, pp. 2322-2330
-
-
Iwamoto, R.1
Higashiyama, S.2
Mitamura, T.3
-
25
-
-
0037429727
-
ErbBs in mammary development
-
Stern D. ErbBs in mammary development. Exp Cell Res 2003; 284: 89-98.
-
(2003)
Exp Cell Res
, vol.284
, pp. 89-98
-
-
Stern, D.1
-
26
-
-
33646140934
-
ErbB and HB-EGF signaling in heart development and function
-
Iwamoto R, Mekada E. ErbB and HB-EGF signaling in heart development and function. Cell Struct Funct 2006; 31: 1-14.
-
(2006)
Cell Struct Funct
, vol.31
, pp. 1-14
-
-
Iwamoto, R.1
Mekada, E.2
-
27
-
-
36048985044
-
The epidermal growth factor receptor: From development to tumorigenesis
-
Sibilia M, Kroismayr R, Lichtenberger B, et al. The epidermal growth factor receptor: from development to tumorigenesis. Differentiation 2007; 75: 770-87.
-
(2007)
Differentiation
, vol.75
, pp. 770-787
-
-
Sibilia, M.1
Kroismayr, R.2
Lichtenberger, B.3
-
28
-
-
43949084738
-
Neuregulin 1 in neural development, synaptic plasticity and schizophrenia
-
Mei L, Xiong W. Neuregulin 1 in neural development, synaptic plasticity and schizophrenia. Nat Rev Neurosci 2008; 9: 437-52.
-
(2008)
Nat Rev Neurosci
, vol.9
, pp. 437-452
-
-
Mei, L.1
Xiong, W.2
-
29
-
-
0028785406
-
Aberrant neural and cardiac development in mice lacking the ErbB4 neuregulin receptor
-
Gassmann M, Casagranda F, Orioli D, et al. Aberrant neural and cardiac development in mice lacking the ErbB4 neuregulin receptor. Nature 1995; 378: 390-4.
-
(1995)
Nature
, vol.378
, pp. 390-394
-
-
Gassmann, M.1
Casagranda, F.2
Orioli, D.3
-
30
-
-
0028884413
-
Requirement for neuregulin receptor erbB2 in neural and cardiac development
-
Lee KF, Simon H, Chen H, et al. Requirement for neuregulin receptor erbB2 in neural and cardiac development. Nature 1995; 378: 394-8.
-
(1995)
Nature
, vol.378
, pp. 394-398
-
-
Lee, K.F.1
Simon, H.2
Chen, H.3
-
31
-
-
0028827104
-
Multiple essential functions of neuregulin in development
-
Meyer D, Birchmeier C. Multiple essential functions of neuregulin in development. Nature 1995; 378: 386-90.
-
(1995)
Nature
, vol.378
, pp. 386-390
-
-
Meyer, D.1
Birchmeier, C.2
-
32
-
-
0028829096
-
Cell-cell signalling. neu tack on neuregulin
-
Marchionni MA. Cell-cell signalling. neu tack on neuregulin. Nature 1995; 378: 334-5.
-
(1995)
Nature
, vol.378
, pp. 334-335
-
-
Marchionni, M.A.1
-
33
-
-
0034091647
-
Mice mutant for Egfr and Shp2 have defective cardiac semilunar valvulogenesis
-
Chen B, Bronson RT, Klaman LD, et al. Mice mutant for Egfr and Shp2 have defective cardiac semilunar valvulogenesis. Nat Genet 2000; 24: 296-9.
-
(2000)
Nat Genet
, vol.24
, pp. 296-299
-
-
Chen, B.1
Bronson, R.T.2
Klaman, L.D.3
-
34
-
-
0037453001
-
Heparin-binding EGF-like growth factor and ErbB signaling is essential for heart function
-
Iwamoto R, Yamazaki S, Asakura M, et al. Heparin-binding EGF-like growth factor and ErbB signaling is essential for heart function. Proc Natl Acad Sci USA 2003; 100: 3221-6.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 3221-3226
-
-
Iwamoto, R.1
Yamazaki, S.2
Asakura, M.3
-
35
-
-
0037507267
-
Defective valvulo-genesis in HB-EGF and TACE-null mice is associated with aberrant BMP signaling
-
Jackson LF, Qiu TH, Sunnarborg SW, et al. Defective valvulo-genesis in HB-EGF and TACE-null mice is associated with aberrant BMP signaling. EMBO J 2003; 22: 2704-16.
-
(2003)
EMBO J
, vol.22
, pp. 2704-2716
-
-
Jackson, L.F.1
Qiu, T.H.2
Sunnarborg, S.W.3
-
36
-
-
0031454062
-
ErbB3 is required for normal cerebellar and cardiac development: A comparison with ErbB2-and heregulin-deficient mice
-
Erickson SL, O'Shea KS, Ghaboosi N, et al. ErbB3 is required for normal cerebellar and cardiac development: a comparison with ErbB2-and heregulin-deficient mice. Development 1997; 124: 4999-5011.
-
(1997)
Development
, vol.124
, pp. 4999-5011
-
-
Erickson, S.L.1
O'Shea, K.S.2
Ghaboosi, N.3
-
37
-
-
33745828702
-
EGF-ERBB signalling: Towards the systems level
-
Citri A, Yarden Y. EGF-ERBB signalling: towards the systems level. Nat Rev Mol Cell Biol 2006; 7: 505-16.
-
(2006)
Nat Rev Mol Cell Biol
, vol.7
, pp. 505-516
-
-
Citri, A.1
Yarden, Y.2
-
38
-
-
33746905531
-
Phosphotyrosine interactome of the ErbB-receptor kinase family
-
Schulze W, Deng L, Mann M. Phosphotyrosine interactome of the ErbB-receptor kinase family. Mol Syst Biol 2005; 1: 2005.0008.
-
(2005)
Mol Syst Biol
, vol.1
, Issue.2005
, pp. 0008
-
-
Schulze, W.1
Deng, L.2
Mann, M.3
-
39
-
-
19244379078
-
Synergism between vascular endothelial growth factor and placental growth factor contributes to angiogenesis and plasma extravasation in pathological conditions
-
Carmeliet P, Moons L, Luttun A, et al. Synergism between vascular endothelial growth factor and placental growth factor contributes to angiogenesis and plasma extravasation in pathological conditions. Nat Med 2001; 7: 575-83.
-
(2001)
Nat Med
, vol.7
, pp. 575-583
-
-
Carmeliet, P.1
Moons, L.2
Luttun, A.3
-
40
-
-
33749367271
-
Loss of HB-EGF in smooth muscle or endothelial cell lineages causes heart malformation
-
Nanba D, Kinugasa Y, Morimoto C, et al. Loss of HB-EGF in smooth muscle or endothelial cell lineages causes heart malformation. Biochem Biophys Res Commun 2006; 350: 315-21.
-
(2006)
Biochem Biophys Res Commun
, vol.350
, pp. 315-321
-
-
Nanba, D.1
Kinugasa, Y.2
Morimoto, C.3
-
41
-
-
0041914499
-
Angiopoietin regulated recruitment of vascular smooth muscle cells by endothelial-derived heparin binding EGF-like growth factor
-
Iivanainen E, Nelimarkka L, Elenius V, et al. Angiopoietin regulated recruitment of vascular smooth muscle cells by endothelial-derived heparin binding EGF-like growth factor. FASEB J 2003; 17: 1609-21.
-
(2003)
FASEB J
, vol.17
, pp. 1609-1621
-
-
Iivanainen, E.1
Nelimarkka, L.2
Elenius, V.3
-
42
-
-
0037341379
-
Blockade of epidermal growth factor receptor signaling in tumor cells and tumorassociated endothelial cells for therapy of androgen-independent human prostate cancer growing in the bone of nude mice
-
Kim SJ, Uehara H, Karashima T, et al. Blockade of epidermal growth factor receptor signaling in tumor cells and tumorassociated endothelial cells for therapy of androgen-independent human prostate cancer growing in the bone of nude mice. Clin Cancer Res 2003; 9: 1200-10.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 1200-1210
-
-
Kim, S.J.1
Uehara, H.2
Karashima, T.3
-
43
-
-
33644546368
-
Tumor endothelial cells express epidermal growth factor receptor (EGFR) but not ErbB3 and are responsive to EGF and to EGFR kinase inhibitors
-
Amin DN, Hida K, Bielenberg DR, et al. Tumor endothelial cells express epidermal growth factor receptor (EGFR) but not ErbB3 and are responsive to EGF and to EGFR kinase inhibitors. Cancer Res 2006; 66: 2173-80.
-
(2006)
Cancer Res
, vol.66
, pp. 2173-2180
-
-
Amin, D.N.1
Hida, K.2
Bielenberg, D.R.3
-
44
-
-
0036733591
-
Blockade of epidermal growth factor receptor signaling on tumor cells and tumor-associated endothelial cells for therapy of human carcinomas
-
Baker CH, Kedar D, McCarty MF, et al. Blockade of epidermal growth factor receptor signaling on tumor cells and tumor-associated endothelial cells for therapy of human carcinomas. Am J Pathol 2002; 161: 929-38.
-
(2002)
Am J Pathol
, vol.161
, pp. 929-938
-
-
Baker, C.H.1
Kedar, D.2
McCarty, M.F.3
-
45
-
-
0022018803
-
New functions of epidermal growth factor: Stimulation of capillary endothelial cell migration and matrix dependent proliferation
-
McAuslan BR, Bender V, Reilly W, et al. New functions of epidermal growth factor: stimulation of capillary endothelial cell migration and matrix dependent proliferation. Cell Biol Int Rep 1985; 9: 175-82.
-
(1985)
Cell Biol Int Rep
, vol.9
, pp. 175-182
-
-
McAuslan, B.R.1
Bender, V.2
Reilly, W.3
-
46
-
-
0022501030
-
Transforming growth factor-alpha: A more potent angiogenic mediator than epidermal growth factor
-
Schreiber AB, Winkler ME, Derynck R. Transforming growth factor-alpha: a more potent angiogenic mediator than epidermal growth factor. Science 1986; 232: 1250-3.
-
(1986)
Science
, vol.232
, pp. 1250-1253
-
-
Schreiber, A.B.1
Winkler, M.E.2
Derynck, R.3
-
47
-
-
0026980157
-
A model system for tumor angiogenesis: Involvement of transforming growth factor-alpha in tube formation of human microvascular endothelial cells induced by esophageal cancer cells
-
Okamura K, Morimoto A, Hamanaka R, et al. A model system for tumor angiogenesis: involvement of transforming growth factor-alpha in tube formation of human microvascular endothelial cells induced by esophageal cancer cells. Biochem Biophys Res Commun 1992; 186: 1471-9.
-
(1992)
Biochem Biophys Res Commun
, vol.186
, pp. 1471-1479
-
-
Okamura, K.1
Morimoto, A.2
Hamanaka, R.3
-
48
-
-
0030050626
-
Heparin-binding epidermal growth factor-like growth factor: P91 activation induction of plasminogen activator/inhibitor, and tubular morphogenesis in human microvascular endothelial cells
-
Ushiro S, Ono M, Izumi H, et al. Heparin-binding epidermal growth factor-like growth factor: p91 activation induction of plasminogen activator/inhibitor, and tubular morphogenesis in human microvascular endothelial cells. Jpn J Cancer Res 1996; 87: 68-77.
-
(1996)
Jpn J Cancer Res
, vol.87
, pp. 68-77
-
-
Ushiro, S.1
Ono, M.2
Izumi, H.3
-
49
-
-
0032478654
-
Intercellular communication between vascular smooth muscle and endothelial cells mediated by heparin-binding epidermal growth factor-like growth factor and vascular endothelial growth factor
-
Abramovitch R, Neeman M, Reich R, et al. Intercellular communication between vascular smooth muscle and endothelial cells mediated by heparin-binding epidermal growth factor-like growth factor and vascular endothelial growth factor. FEBS Lett 1998; 425: 441-7.
-
(1998)
FEBS Lett
, vol.425
, pp. 441-447
-
-
Abramovitch, R.1
Neeman, M.2
Reich, R.3
-
50
-
-
0036570203
-
ZD1839 (Iressa) induces antiangiogenic effects through inhibition of epidermal growth factor receptor tyrosine kinase
-
Hirata A, Ogawa S, Kometani T, et al. ZD1839 (Iressa) induces antiangiogenic effects through inhibition of epidermal growth factor receptor tyrosine kinase. Cancer Res 2002; 62: 2554-60.
-
(2002)
Cancer Res
, vol.62
, pp. 2554-2560
-
-
Hirata, A.1
Ogawa, S.2
Kometani, T.3
-
51
-
-
0037313638
-
Betacellulin induces angiogenesis through activation of mitogen-activated protein kinase and phosphatidylinositol 3'-kinase in endothelial cell
-
Kim HS, Shin HS, Kwak HJ, et al. Betacellulin induces angiogenesis through activation of mitogen-activated protein kinase and phosphatidylinositol 3'-kinase in endothelial cell. FASEB J 2003; 17: 318-20.
-
(2003)
FASEB J
, vol.17
, pp. 318-320
-
-
Kim, H.S.1
Shin, H.S.2
Kwak, H.J.3
-
52
-
-
0018745431
-
The angiogenic activity of the fibroblast and epidermal growth factor
-
Gospodarowicz D, Bialecki H, Thakral TK. The angiogenic activity of the fibroblast and epidermal growth factor. Exp Eye Res 1979; 28: 501-14.
-
(1979)
Exp Eye Res
, vol.28
, pp. 501-514
-
-
Gospodarowicz, D.1
Bialecki, H.2
Thakral, T.K.3
-
53
-
-
0025904265
-
A heparin-binding growth factor secreted by macrophage-like cells that is related to EGF
-
Higashiyama S, Abraham JA, Miller J, et al. A heparin-binding growth factor secreted by macrophage-like cells that is related to EGF. Science 1991; 251: 936-9.
-
(1991)
Science
, vol.251
, pp. 936-939
-
-
Higashiyama, S.1
Abraham, J.A.2
Miller, J.3
-
54
-
-
0033574017
-
Epiregulin is a potent vascular smooth muscle cell-derived mitogen induced by angiotensin II, endothelin-1, and thrombin
-
Taylor DS, Cheng X, Pawlowski JE, et al. Epiregulin is a potent vascular smooth muscle cell-derived mitogen induced by angiotensin II, endothelin-1, and thrombin. Proc Natl Acad Sci USA 1999; 96: 1633-8.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 1633-1638
-
-
Taylor, D.S.1
Cheng, X.2
Pawlowski, J.E.3
-
55
-
-
0035097425
-
Immunohistochemical localization of Betacellulin, a member of epidermal growth factor family, in atherosclerotic plaques of human aorta
-
Tamura R, Miyagawa J, Nishida M, et al. Immunohistochemical localization of Betacellulin, a member of epidermal growth factor family, in atherosclerotic plaques of human aorta. Atherosclerosis 2001; 155: 413-23.
-
(2001)
Atherosclerosis
, vol.155
, pp. 413-423
-
-
Tamura, R.1
Miyagawa, J.2
Nishida, M.3
-
56
-
-
0037459082
-
Amphiregulin is a potent mitogen for the vascular smooth muscle cell line
-
Kato M, Inazu T, Kawai Y, et al. Amphiregulin is a potent mitogen for the vascular smooth muscle cell line, A7r5. Biochem Biophys Res Commun 2003; 301: 1109-15.
-
(2003)
A7r5. Biochem Biophys Res Commun
, vol.301
, pp. 1109-1115
-
-
Kato, M.1
Inazu, T.2
Kawai, Y.3
-
57
-
-
0344825218
-
Epiregulin as a major autocrine/paracrine factor released from ERK- and p38MAPK-activated vascular smooth muscle cells
-
Takahashi M, Hayashi K, Yoshida K, et al. Epiregulin as a major autocrine/paracrine factor released from ERK- and p38MAPK-activated vascular smooth muscle cells. Circulation 2003; 108: 2524-9.
-
(2003)
Circulation
, vol.108
, pp. 2524-2529
-
-
Takahashi, M.1
Hayashi, K.2
Yoshida, K.3
-
58
-
-
4143114492
-
Signal transduction of betacellulin in growth and migration of vascular smooth muscle cells
-
Mifune M, Ohtsu H, Suzuki H, et al. Signal transduction of betacellulin in growth and migration of vascular smooth muscle cells. Am J Physiol Cell Physiol 2004; 287: C807-13.
-
(2004)
Am J Physiol Cell Physiol
, vol.287
-
-
Mifune, M.1
Ohtsu, H.2
Suzuki, H.3
-
59
-
-
0032768156
-
Role of PDGF-B and PDGFR-beta in recruitment of vascular smooth muscle cells and pericytes during embryonic blood vessel formation in the mouse
-
Hellstrom M, Kalen M, Lindahl P, et al. Role of PDGF-B and PDGFR-beta in recruitment of vascular smooth muscle cells and pericytes during embryonic blood vessel formation in the mouse. Development 1999; 126: 3047-55.
-
(1999)
Development
, vol.126
, pp. 3047-3055
-
-
Hellstrom, M.1
Kalen, M.2
Lindahl, P.3
-
60
-
-
44349143198
-
Bone marrow-derived circulating endothelial precursors do not contribute to vascular endothelium and are not needed for tumor growth
-
Purhonen S, Palm J, Rossi D, et al. Bone marrow-derived circulating endothelial precursors do not contribute to vascular endothelium and are not needed for tumor growth. Proc Natl Acad Sci USA 2008; 105: 6620-5.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 6620-6625
-
-
Purhonen, S.1
Palm, J.2
Rossi, D.3
-
61
-
-
0033393696
-
Neuregulin activation of ErbB receptors in vascular endothelium leads to angiogenesis
-
Russell KS, Stern DF, Polverini PJ, et al. Neuregulin activation of ErbB receptors in vascular endothelium leads to angiogenesis. Am J Physiol 1999; 277(6 Pt 2): H2205-11.
-
(1999)
Am J Physiol
, vol.277
, Issue.6 PART 2
-
-
Russell, K.S.1
Stern, D.F.2
Polverini, P.J.3
-
62
-
-
0034691674
-
Heregulin selectively upregulates vascular endothelial growth factor secretion in cancer cells and stimulates angiogenesis
-
Yen L, You XL, Al Moustafa AE, et al. Heregulin selectively upregulates vascular endothelial growth factor secretion in cancer cells and stimulates angiogenesis. Oncogene 2000; 19: 3460-9.
-
(2000)
Oncogene
, vol.19
, pp. 3460-3469
-
-
Yen, L.1
You, X.L.2
Al Moustafa, A.E.3
-
63
-
-
0034671927
-
Vascular endothelial growth factor up-regulation via p21-activated kinase-1 signaling regulates heregulin-beta1-mediated angiogenesis
-
Bagheri-Yarmand R, Vadlamudi RK, Wang RA, et al. Vascular endothelial growth factor up-regulation via p21-activated kinase-1 signaling regulates heregulin-beta1-mediated angiogenesis. J Biol Chem 2000; 275: 39451-7.
-
(2000)
J Biol Chem
, vol.275
, pp. 39451-39457
-
-
Bagheri-Yarmand, R.1
Vadlamudi, R.K.2
Wang, R.A.3
-
64
-
-
34250722576
-
Neuregulin-1 attenuates neointimal formation following vascular injury and inhibits the proliferation of vascular smooth muscle cells
-
Clement CM, Thomas LK, Mou Y, et al. Neuregulin-1 attenuates neointimal formation following vascular injury and inhibits the proliferation of vascular smooth muscle cells. J Vasc Res 2007; 44: 303-12.
-
(2007)
J Vasc Res
, vol.44
, pp. 303-312
-
-
Clement, C.M.1
Thomas, L.K.2
Mou, Y.3
-
65
-
-
0027412319
-
Epidermal growth factor stimulates vascular endothelial growth factor production by human malignant glioma cells: A model of glioblastoma multiforme patho-physiology
-
Goldman CK, Kim J, Wong WL, et al. Epidermal growth factor stimulates vascular endothelial growth factor production by human malignant glioma cells: a model of glioblastoma multiforme patho-physiology. Mol Biol Cell 1993; 4: 121-33.
-
(1993)
Mol Biol Cell
, vol.4
, pp. 121-133
-
-
Goldman, C.K.1
Kim, J.2
Wong, W.L.3
-
66
-
-
0035116241
-
Vascular endothelial growth factor family members are differentially regulated by c-erbB signaling in head and neck squamous carcinoma cells
-
O-charoenrat P, Rhys-Evans P, Modjtahedi H, et al. Vascular endothelial growth factor family members are differentially regulated by c-erbB signaling in head and neck squamous carcinoma cells. Clin Exp Metastasis 2000; 18: 155-61.
-
(2000)
Clin Exp Metastasis
, vol.18
, pp. 155-161
-
-
O-Charoenrat, P.1
Rhys-Evans, P.2
Modjtahedi, H.3
-
67
-
-
0037429570
-
Induction of neuropilin-1 and vascular endothelial growth factor by epidermal growth factor in human gastric cancer cells
-
Akagi M, Kawaguchi M, Liu W, et al. Induction of neuropilin-1 and vascular endothelial growth factor by epidermal growth factor in human gastric cancer cells. Br J Cancer 2003; 88: 796-802.
-
(2003)
Br J Cancer
, vol.88
, pp. 796-802
-
-
Akagi, M.1
Kawaguchi, M.2
Liu, W.3
-
68
-
-
33744903661
-
PTEN/Akt signaling through epidermal growth factor receptor is prerequisite for angiogenesis by hepatocellular carcinoma cells that is susceptible to inhibition by gefitinib
-
Ueda S, Basaki Y, Yoshie M, et al. PTEN/Akt signaling through epidermal growth factor receptor is prerequisite for angiogenesis by hepatocellular carcinoma cells that is susceptible to inhibition by gefitinib. Cancer Res 2006; 66: 5346-53.
-
(2006)
Cancer Res
, vol.66
, pp. 5346-5353
-
-
Ueda, S.1
Basaki, Y.2
Yoshie, M.3
-
69
-
-
44949117528
-
Heregulin-induced activation of ErbB3 by EGFR tyrosine kinase activity promotes tumor growth and metastasis in melanoma cells
-
Ueno Y, Sakurai H, Tsunoda S, et al. Heregulin-induced activation of ErbB3 by EGFR tyrosine kinase activity promotes tumor growth and metastasis in melanoma cells. Int J Cancer 2008; 123: 340-7.
-
(2008)
Int J Cancer
, vol.123
, pp. 340-347
-
-
Ueno, Y.1
Sakurai, H.2
Tsunoda, S.3
-
70
-
-
0242425875
-
Proteolytic release of the carboxy-terminal fragment of proHB-EGF causes nuclear export of PLZF
-
Nanba D, Mammoto A, Hashimoto K, et al. Proteolytic release of the carboxy-terminal fragment of proHB-EGF causes nuclear export of PLZF. J Cell Biol 2003; 163: 489-502.
-
(2003)
J Cell Biol
, vol.163
, pp. 489-502
-
-
Nanba, D.1
Mammoto, A.2
Hashimoto, K.3
-
71
-
-
0034681260
-
Regulated intramembrane proteolysis: A control mechanism conserved from bacteria to humans
-
Brown M, Ye J, Rawson R, et al. Regulated intramembrane proteolysis: a control mechanism conserved from bacteria to humans. Cell 2000; 100: 391-8.
-
(2000)
Cell
, vol.100
, pp. 391-398
-
-
Brown, M.1
Ye, J.2
Rawson, R.3
-
72
-
-
48349129069
-
Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation
-
Tammela T, Zarkada G, Wallgard E, et al. Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation. Nature 2008; 454: 656-60.
-
(2008)
Nature
, vol.454
, pp. 656-660
-
-
Tammela, T.1
Zarkada, G.2
Wallgard, E.3
-
73
-
-
40149107884
-
ErbB-directed immunotherapy: Antibodies in current practice and promising new agents
-
Friedländer E, Barok M, Szöllosi J, et al. ErbB-directed immunotherapy: antibodies in current practice and promising new agents. Immunol Lett 2008; 116: 126-40.
-
(2008)
Immunol Lett
, vol.116
, pp. 126-140
-
-
Friedländer, E.1
Barok, M.2
Szöllosi, J.3
-
74
-
-
34347395733
-
Trastuzumab--mechanism of action and use in clinical practice
-
Hudis CA. Trastuzumab--mechanism of action and use in clinical practice. N Engl J Med 2007; 357: 39-51.
-
(2007)
N Engl J Med
, vol.357
, pp. 39-51
-
-
Hudis, C.A.1
-
75
-
-
34447293294
-
Lapatinib plus capecitabine in patients with HER2-positive advanced breast cancer
-
Cameron D. Lapatinib plus capecitabine in patients with HER2-positive advanced breast cancer. Clin Adv Hematol Oncol 2007; 5: 456-8.
-
(2007)
Clin Adv Hematol Oncol
, vol.5
, pp. 456-458
-
-
Cameron, D.1
-
76
-
-
40849147041
-
EGFR antagonists in cancer treatment
-
Ciardiello F, Tortora G. EGFR antagonists in cancer treatment. N Engl J Med 2008; 358: 1160-74.
-
(2008)
N Engl J Med
, vol.358
, pp. 1160-1174
-
-
Ciardiello, F.1
Tortora, G.2
-
77
-
-
33947732977
-
Angiogenesis: An organizing principle for drug discovery?
-
Folkman J. Angiogenesis: an organizing principle for drug discovery? Nat Rev Drug Discov 2007; 6: 273-86.
-
(2007)
Nat Rev Drug Discov
, vol.6
, pp. 273-286
-
-
Folkman, J.1
-
78
-
-
4143066005
-
Direct inhibition of EGF receptor activation in vascular endothelial cells by gefitinib ('Iressa', ZD1839)
-
Hirata A, Uehara H, Izumi K, et al. Direct inhibition of EGF receptor activation in vascular endothelial cells by gefitinib ('Iressa', ZD1839). Cancer Sci 2004; 95: 614-8.
-
(2004)
Cancer Sci
, vol.95
, pp. 614-618
-
-
Hirata, A.1
Uehara, H.2
Izumi, K.3
-
79
-
-
33846202907
-
Molecular mechanisms of epidermal growth factor receptor (EGFR) activation and response to gefitinib and other EGFR-targeting drugs
-
Ono M, Kuwano M. Molecular mechanisms of epidermal growth factor receptor (EGFR) activation and response to gefitinib and other EGFR-targeting drugs. Clin Cancer Res 2006; 12: 7242-51.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 7242-7251
-
-
Ono, M.1
Kuwano, M.2
-
80
-
-
0036681995
-
Modulation of radiation response and tumor-induced angiogenesis after epidermal growth factor receptor inhibition by ZD1839 (Iressa)
-
Huang SM, Li J, Armstrong EA, et al. Modulation of radiation response and tumor-induced angiogenesis after epidermal growth factor receptor inhibition by ZD1839 (Iressa). Cancer Res 2002; 62: 4300-6.
-
(2002)
Cancer Res
, vol.62
, pp. 4300-4306
-
-
Huang, S.M.1
Li, J.2
Armstrong, E.A.3
-
81
-
-
33846309244
-
Oncolytic HSV and erlotinib inhibit tumor growth and angiogenesis in a novel malignant peripheral nerve sheath tumor xenograft model
-
Mahller YY, Vaikunth SS, Currier MA, et al. Oncolytic HSV and erlotinib inhibit tumor growth and angiogenesis in a novel malignant peripheral nerve sheath tumor xenograft model. Mol Ther 2007; 15: 279-86.
-
(2007)
Mol Ther
, vol.15
, pp. 279-286
-
-
Mahller, Y.Y.1
Vaikunth, S.S.2
Currier, M.A.3
-
82
-
-
4444280232
-
Antitumor activity of ZD6126, a novel vascular-targeting agent, is enhanced when combined with ZD1839, an epidermal growth factor receptor tyrosine kinase inhibitor, and potentiates the effects of radiation in a human non-small cell lung cancer xenograft model
-
Raben D, Bianco C, Damiano V, et al. Antitumor activity of ZD6126, a novel vascular-targeting agent, is enhanced when combined with ZD1839, an epidermal growth factor receptor tyrosine kinase inhibitor, and potentiates the effects of radiation in a human non-small cell lung cancer xenograft model. Mol Cancer Ther 2004; 3: 977-83.
-
(2004)
Mol Cancer Ther
, vol.3
, pp. 977-983
-
-
Raben, D.1
Bianco, C.2
Damiano, V.3
-
83
-
-
0001223491
-
Neutralizing antibodies against epidermal growth factor and ErbB-2/neu receptor tyrosine kinases down-regulate vascular endothelial growth factor production by tumor cells in vitro and in vivo: Angiogenic implications for signal transduction therapy of solid tumors
-
Petit AM, Rak J, Hung MC, et al. Neutralizing antibodies against epidermal growth factor and ErbB-2/neu receptor tyrosine kinases down-regulate vascular endothelial growth factor production by tumor cells in vitro and in vivo: angiogenic implications for signal transduction therapy of solid tumors. Am J Pathol 1997; 151: 1523-30.
-
(1997)
Am J Pathol
, vol.151
, pp. 1523-1530
-
-
Petit, A.M.1
Rak, J.2
Hung, M.C.3
-
84
-
-
0032972944
-
Anti-epidermal growth factor receptor antibody C225 inhibits angiogenesis in human transitional cell carcinoma growing orthotopically in nude mice
-
Perrotte P, Matsumoto T, Inoue K, et al. Anti-epidermal growth factor receptor antibody C225 inhibits angiogenesis in human transitional cell carcinoma growing orthotopically in nude mice. Clin Cancer Res 1999; 5: 257-65.
-
(1999)
Clin Cancer Res
, vol.5
, pp. 257-265
-
-
Perrotte, P.1
Matsumoto, T.2
Inoue, K.3
-
85
-
-
0033818695
-
Antiangiogenic and antitumor activity of anti-epidermal growth factor receptor C225 monoclonal antibody in combination with vascular endothelial growth factor antisense oligonucleotide in human GEO colon cancer cells
-
Ciardiello F, Bianco R, Damiano V, et al. Antiangiogenic and antitumor activity of anti-epidermal growth factor receptor C225 monoclonal antibody in combination with vascular endothelial growth factor antisense oligonucleotide in human GEO colon cancer cells. Clin Cancer Res 2000; 6: 3739-47.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 3739-3747
-
-
Ciardiello, F.1
Bianco, R.2
Damiano, V.3
-
86
-
-
18844473781
-
Epidermal growth factor receptor blockade with C225 plus gemcitabine results in regression of human pancreatic carcinoma growing orthotopically in nude mice by antiangiogenic mechanisms
-
Bruns CJ, Harbison MT, Davis DW, et al. Epidermal growth factor receptor blockade with C225 plus gemcitabine results in regression of human pancreatic carcinoma growing orthotopically in nude mice by antiangiogenic mechanisms. Clin Cancer Res 2000; 6: 1936-48.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 1936-1948
-
-
Bruns, C.J.1
Harbison, M.T.2
Davis, D.W.3
-
88
-
-
10744221013
-
Preclinical and clinical evaluations of ABX-EGF, a fully human anti-epidermal growth factor receptor antibody
-
Foon K, Yang X, Weiner L, et al. Preclinical and clinical evaluations of ABX-EGF, a fully human anti-epidermal growth factor receptor antibody. Int J Radiat Oncol Biol Phys 2004; 58: 984-90.
-
(2004)
Int J Radiat Oncol Biol Phys
, vol.58
, pp. 984-990
-
-
Foon, K.1
Yang, X.2
Weiner, L.3
-
89
-
-
0034896362
-
Inhibition of growth factor production and angiogenesis in human cancer cells by ZD1839 (Ir-essa), a selective epidermal growth factor receptor tyrosine kinase inhibitor
-
Ciardiello F, Caputo R, Bianco R, et al. Inhibition of growth factor production and angiogenesis in human cancer cells by ZD1839 (Ir-essa), a selective epidermal growth factor receptor tyrosine kinase inhibitor. Clin Cancer Res 2001; 7: 1459-65.
-
(2001)
Clin Cancer Res
, vol.7
, pp. 1459-1465
-
-
Ciardiello, F.1
Caputo, R.2
Bianco, R.3
-
90
-
-
33645499486
-
EGFR tyrosine kinase inhibitors decrease VEGF expression by both hypoxia-inducible factor (HIF)-1-independent and HIF-1-dependent mechanisms
-
Pore N, Jiang Z, Gupta A, et al. EGFR tyrosine kinase inhibitors decrease VEGF expression by both hypoxia-inducible factor (HIF)-1-independent and HIF-1-dependent mechanisms. Cancer Res 2006; 66: 3197-204.
-
(2006)
Cancer Res
, vol.66
, pp. 3197-3204
-
-
Pore, N.1
Jiang, Z.2
Gupta, A.3
-
91
-
-
35848945096
-
Response to trastuzu-mab, erlotinib, and bevacizumab, alone and in combination, is correlated with the level of human epidermal growth factor receptor-2 expression in human breast cancer cell lines
-
Emlet DR, Brown KA, Kociban DL, et al. Response to trastuzu-mab, erlotinib, and bevacizumab, alone and in combination, is correlated with the level of human epidermal growth factor receptor-2 expression in human breast cancer cell lines. Mol Cancer Ther 2007; 6: 2664-74.
-
(2007)
Mol Cancer Ther
, vol.6
, pp. 2664-2674
-
-
Emlet, D.R.1
Brown, K.A.2
Kociban, D.L.3
-
92
-
-
33750584030
-
HER2 signaling modulates the equilibrium between pro- and antiangiogenic factors via distinct pathways: Implications for HER2-targeted antibody therapy
-
Wen XF, Yang G, Mao W, et al. HER2 signaling modulates the equilibrium between pro- and antiangiogenic factors via distinct pathways: implications for HER2-targeted antibody therapy. Oncogene 2006; 25: 6986-96.
-
(2006)
Oncogene
, vol.25
, pp. 6986-6996
-
-
Wen, X.F.1
Yang, G.2
Mao, W.3
-
93
-
-
33847715433
-
Human epidermal growth factor receptor 2 regulates angiopoietin-2 expression in breast cancer via AKT and mitogen-activated protein kinase pathways
-
Niu G, Carter W. Human epidermal growth factor receptor 2 regulates angiopoietin-2 expression in breast cancer via AKT and mitogen-activated protein kinase pathways. Cancer Res 2007; 67: 1487-93.
-
(2007)
Cancer Res
, vol.67
, pp. 1487-1493
-
-
Niu, G.1
Carter, W.2
-
94
-
-
0036096775
-
Inhibition of angiogenesis by the antiepidermal growth factor receptor antibody Im-Clone C225 in androgen-independent prostate cancer growing orthotopically in nude mice
-
Karashima T, Sweeney P, Slaton JW, et al. Inhibition of angiogenesis by the antiepidermal growth factor receptor antibody Im-Clone C225 in androgen-independent prostate cancer growing orthotopically in nude mice. Clin Cancer Res 2002; 8: 1253-64.
-
(2002)
Clin Cancer Res
, vol.8
, pp. 1253-1264
-
-
Karashima, T.1
Sweeney, P.2
Slaton, J.W.3
-
95
-
-
33745590870
-
Anti-tumor activity of the combination of cetuximab, an anti-EGFR blocking monoclonal antibody and ZD6474, an inhibitor of VEGFR and EGFR tyrosine kinases
-
Morelli MP, Cascone T, Troiani T, et al. Anti-tumor activity of the combination of cetuximab, an anti-EGFR blocking monoclonal antibody and ZD6474, an inhibitor of VEGFR and EGFR tyrosine kinases. J Cell Physiol 2006; 208: 344-53.
-
(2006)
J Cell Physiol
, vol.208
, pp. 344-353
-
-
Morelli, M.P.1
Cascone, T.2
Troiani, T.3
-
96
-
-
0034489116
-
Paclitaxel enhances the effects of the anti-epidermal growth factor receptor monoclonal antibody ImClone C225 in mice with metastatic human bladder transitional cell carcinoma
-
Inoue K, Slaton JW, Perrotte P, et al. Paclitaxel enhances the effects of the anti-epidermal growth factor receptor monoclonal antibody ImClone C225 in mice with metastatic human bladder transitional cell carcinoma. Clin Cancer Res 2000; 6: 4874-84.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 4874-4884
-
-
Inoue, K.1
Slaton, J.W.2
Perrotte, P.3
-
97
-
-
0028819660
-
Biological efficacy of a chimeric antibody to the epidermal growth factor receptor in a human tumor xenograft model
-
Goldstein NI, Prewett M, Zuklys K, et al. Biological efficacy of a chimeric antibody to the epidermal growth factor receptor in a human tumor xenograft model. Clin Cancer Res 1995; 1: 1311-8.
-
(1995)
Clin Cancer Res
, vol.1
, pp. 1311-1318
-
-
Goldstein, N.I.1
Prewett, M.2
Zuklys, K.3
-
98
-
-
0036561431
-
Molecular inhibition of angiogenesis and metastatic potential in human squamous cell carcinomas after epidermal growth factor receptor blockade
-
Huang SM, Li J, Harari PM. Molecular inhibition of angiogenesis and metastatic potential in human squamous cell carcinomas after epidermal growth factor receptor blockade. Mol Cancer Ther 2002; 1: 507-14.
-
(2002)
Mol Cancer Ther
, vol.1
, pp. 507-514
-
-
Huang, S.M.1
Li, J.2
Harari, P.M.3
-
99
-
-
20444431504
-
The antitumor and antiangiogenic activity of vascular endothelial growth factor receptor inhibition is potentiated by ErbB1 blockade
-
Sini P, Wyder L, Schnell C, et al. The antitumor and antiangiogenic activity of vascular endothelial growth factor receptor inhibition is potentiated by ErbB1 blockade. Clin Cancer Res 2005; 11: 4521-32.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 4521-4532
-
-
Sini, P.1
Wyder, L.2
Schnell, C.3
-
100
-
-
4444324184
-
Simultaneously targeting epidermal growth factor receptor tyrosine kinase and cyclooxygenase-2, an efficient approach to inhibition of squamous cell carcinoma of the head and neck
-
Chen Z, Zhang X, Li M, et al. Simultaneously targeting epidermal growth factor receptor tyrosine kinase and cyclooxygenase-2, an efficient approach to inhibition of squamous cell carcinoma of the head and neck. Clin Cancer Res 2004; 10: 5930-9.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 5930-5939
-
-
Chen, Z.1
Zhang, X.2
Li, M.3
-
101
-
-
45449113946
-
Targeting EGFR activity in blood vessels is sufficient to inhibit tumor growth and is accompanied by an increase in VEGFR-2 dependence in tumor endothelial cells
-
Amin D, Bielenberg D, Lifshits E, et al. Targeting EGFR activity in blood vessels is sufficient to inhibit tumor growth and is accompanied by an increase in VEGFR-2 dependence in tumor endothelial cells. Microvasc Res 2008; 76: 15-22.
-
(2008)
Microvasc Res
, vol.76
, pp. 15-22
-
-
Amin, D.1
Bielenberg, D.2
Lifshits, E.3
-
102
-
-
10744228311
-
Human epidermal growth factor receptor signaling contributes to tumor growth via angiogenesis in her2/neu-expressing experimental Wilms' tumor
-
Yokoi A, McCrudden KW, Huang J, et al. Human epidermal growth factor receptor signaling contributes to tumor growth via angiogenesis in her2/neu-expressing experimental Wilms' tumor. J Pediatr Surg 2003; 38: 1569-73.
-
(2003)
J Pediatr Surg
, vol.38
, pp. 1569-1573
-
-
Yokoi, A.1
McCrudden, K.W.2
Huang, J.3
-
103
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan D, Weinberg R. The hallmarks of cancer. Cell 2000; 100: 57-70.
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.2
-
104
-
-
3142774878
-
AEE788: A dual family epidermal growth factor receptor/ErbB2 and vascular endothelial growth factor receptor tyrosine kinase inhibitor with antitumor and antiangiogenic activity
-
Traxler P, Allegrini PR, Brandt R, et al. AEE788: a dual family epidermal growth factor receptor/ErbB2 and vascular endothelial growth factor receptor tyrosine kinase inhibitor with antitumor and antiangiogenic activity. Cancer Res 2004; 64: 4931-41.
-
(2004)
Cancer Res
, vol.64
, pp. 4931-4941
-
-
Traxler, P.1
Allegrini, P.R.2
Brandt, R.3
-
105
-
-
33846850223
-
Vandetanib (ZD6474): An orally available receptor tyrosine kinase inhibitor that selectively targets pathways critical for tumor growth and angiogenesis
-
Herbst RS, Heymach JV, O'Reilly MS, et al. Vandetanib (ZD6474): an orally available receptor tyrosine kinase inhibitor that selectively targets pathways critical for tumor growth and angiogenesis. Expert Opin Investig Drugs 2007; 16: 239-49.
-
(2007)
Expert Opin Investig Drugs
, vol.16
, pp. 239-249
-
-
Herbst, R.S.1
Heymach, J.V.2
O'Reilly, M.S.3
-
106
-
-
46749097472
-
Statins activate a mitochondria-operated pathway of apoptosis in breast tumor cells by a mechanism regulated by ErbB2 and dependent on the prenylation of proteins
-
Herrero-Martin G, López-Rivas A. Statins activate a mitochondria-operated pathway of apoptosis in breast tumor cells by a mechanism regulated by ErbB2 and dependent on the prenylation of proteins. FEBS Lett 2008; 582: 2589-94.
-
(2008)
FEBS Lett
, vol.582
, pp. 2589-2594
-
-
Herrero-Martin, G.1
López-Rivas, A.2
-
107
-
-
0035160312
-
Impaired recruitment of bonemarrow-derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth
-
Lyden D, Hattori K, Dias S, et al. Impaired recruitment of bonemarrow-derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth. Nat Med 2001; 7: 1194-201.
-
(2001)
Nat Med
, vol.7
, pp. 1194-1201
-
-
Lyden, D.1
Hattori, K.2
Dias, S.3
-
108
-
-
0031915752
-
A flanking attack on cancer
-
Hanahan D. A flanking attack on cancer. Nat Med 1998; 4: 13-14.
-
(1998)
Nat Med
, vol.4
, pp. 13-14
-
-
Hanahan, D.1
-
109
-
-
0031834239
-
A plasticity window for blood vessel remodelling is defined by pericyte coverage of the preformed endothelial network and is regulated by PDGF-B and VEGF
-
Benjamin LE, Hemo I, Keshet E. A plasticity window for blood vessel remodelling is defined by pericyte coverage of the preformed endothelial network and is regulated by PDGF-B and VEGF. Development 1998; 125: 1591-8.
-
(1998)
Development
, vol.125
, pp. 1591-1598
-
-
Benjamin, L.E.1
Hemo, I.2
Keshet, E.3
-
110
-
-
0038476608
-
Benefits of targeting both pericytes and endothelial cells in the tumor vasculature with kinase inhibitors
-
Bergers G, Song S, Meyer-Morse N, et al. Benefits of targeting both pericytes and endothelial cells in the tumor vasculature with kinase inhibitors. J Clin Invest 2003; 111: 1287-95.
-
(2003)
J Clin Invest
, vol.111
, pp. 1287-1295
-
-
Bergers, G.1
Song, S.2
Meyer-Morse, N.3
-
111
-
-
0028851973
-
Expression of growth factor receptors in arterial smooth muscle cells. Dependency on cell phenotype and serum factors
-
Saltis J, Thomas AC, Agrotis A, et al. Expression of growth factor receptors in arterial smooth muscle cells. Dependency on cell phenotype and serum factors. Atherosclerosis 1995; 118: 77-87.
-
(1995)
Atherosclerosis
, vol.118
, pp. 77-87
-
-
Saltis, J.1
Thomas, A.C.2
Agrotis, A.3
-
112
-
-
0034607466
-
Inhibition of AT1 receptor internalization by concanavalin A blocks angiotensin II-induced ERK activation in vascular smooth muscle cells. Involvement of epidermal growth factor receptor proteolysis but not AT1 receptor internalization
-
Tang H, Nishishita T, Fitzgerald T, et al. Inhibition of AT1 receptor internalization by concanavalin A blocks angiotensin II-induced ERK activation in vascular smooth muscle cells. Involvement of epidermal growth factor receptor proteolysis but not AT1 receptor internalization. J Biol Chem 2000; 275: 13420-6.
-
(2000)
J Biol Chem
, vol.275
, pp. 13420-13426
-
-
Tang, H.1
Nishishita, T.2
Fitzgerald, T.3
-
113
-
-
0041356915
-
Betacellulin and amphiregulin induce upregulation of cyclin D1 and DNA synthesis activity through differential signaling pathways in vascular smooth muscle cells
-
Shin HS, Lee HJ, Nishida M, et al. Betacellulin and amphiregulin induce upregulation of cyclin D1 and DNA synthesis activity through differential signaling pathways in vascular smooth muscle cells. Circ Res 2003; 93: 302-10.
-
(2003)
Circ Res
, vol.93
, pp. 302-310
-
-
Shin, H.S.1
Lee, H.J.2
Nishida, M.3
-
114
-
-
33845984583
-
EGF receptor activity modulates apoptosis induced by inhibition of the proteasome of vascular smooth muscle cells
-
Ying WZ, Zhang HG, Sanders PW. EGF receptor activity modulates apoptosis induced by inhibition of the proteasome of vascular smooth muscle cells. J Am Soc Nephrol 2007; 18: 131-42.
-
(2007)
J Am Soc Nephrol
, vol.18
, pp. 131-142
-
-
Ying, W.Z.1
Zhang, H.G.2
Sanders, P.W.3
-
115
-
-
34447503630
-
Platelet-activating factor induces ovine fetal pulmonary venous smooth muscle cell proliferation: Role of epidermal growth factor receptor transactivation
-
Zhou W, Ibe BO, Raj JU. Platelet-activating factor induces ovine fetal pulmonary venous smooth muscle cell proliferation: role of epidermal growth factor receptor transactivation. Am J Physiol Heart Circ Physiol 2007; 292: H2773-81.
-
(2007)
Am J Physiol Heart Circ Physiol
, vol.292
-
-
Zhou, W.1
Ibe, B.O.2
Raj, J.U.3
-
116
-
-
0022452615
-
Expression of epidermal growth factor receptor in human cultured cells and tissues: Relationship to cell lineage and stage of differentiation
-
Real FX, Rettig WJ, Chesa PG, et al. Expression of epidermal growth factor receptor in human cultured cells and tissues: relationship to cell lineage and stage of differentiation. Cancer Res 1986; 46: 4726-31.
-
(1986)
Cancer Res
, vol.46
, pp. 4726-4731
-
-
Real, F.X.1
Rettig, W.J.2
Chesa, P.G.3
-
117
-
-
0023701607
-
Epidermal growth factor receptor in meningiomas is expressed predominantly on endothelial cells
-
Shiurba R, Eng L, Vogel H, et al. Epidermal growth factor receptor in meningiomas is expressed predominantly on endothelial cells. Cancer 1988; 62: 2139-44.
-
(1988)
Cancer
, vol.62
, pp. 2139-2144
-
-
Shiurba, R.1
Eng, L.2
Vogel, H.3
-
118
-
-
0037567558
-
Blockade of epidermal growth factor receptor signaling leads to inhibition of renal cell carcinoma growth in the bone of nude mice
-
Weber K, Doucet M, Price J, et al. Blockade of epidermal growth factor receptor signaling leads to inhibition of renal cell carcinoma growth in the bone of nude mice. Cancer Res 2003; 63: 2940-7.
-
(2003)
Cancer Res
, vol.63
, pp. 2940-2947
-
-
Weber, K.1
Doucet, M.2
Price, J.3
-
119
-
-
27644479545
-
Antivascular therapy for orthotopic human ovarian carcinoma through blockade of the vascular endothelial growth factor and epidermal growth factor receptors
-
Thaker P, Yazici S, Nilsson M, et al. Antivascular therapy for orthotopic human ovarian carcinoma through blockade of the vascular endothelial growth factor and epidermal growth factor receptors. Clin Cancer Res 2005; 11: 4923-33.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 4923-4933
-
-
Thaker, P.1
Yazici, S.2
Nilsson, M.3
-
120
-
-
23244462565
-
Induction of apoptosis in tumor associated endothelial cells and therapy of orthotopic human pancreatic carcinoma in nude mice
-
Yokoi K, Kim S, Thaker P, et al. Induction of apoptosis in tumor associated endothelial cells and therapy of orthotopic human pancreatic carcinoma in nude mice. Neoplasia 2005; 7: 696-704.
-
(2005)
Neoplasia
, vol.7
, pp. 696-704
-
-
Yokoi, K.1
Kim, S.2
Thaker, P.3
-
121
-
-
33748627437
-
Expression of betacellulin and epidermal growth factor receptor in hepatocellular carcinoma: Implications for angiogenesis
-
Moon W, Park H, Yu K, et al. Expression of betacellulin and epidermal growth factor receptor in hepatocellular carcinoma: implications for angiogenesis. Hum Pathol 2006; 37: 1324-32.
-
(2006)
Hum Pathol
, vol.37
, pp. 1324-1332
-
-
Moon, W.1
Park, H.2
Yu, K.3
-
122
-
-
0025049604
-
Endothelium and pericyte interdigitation: Pathway for epidermal growth factor?
-
Wakui S, Furusato M, Tanaka M, et al. Endothelium and pericyte interdigitation: pathway for epidermal growth factor? Microvasc Res 1990; 40: 285-91.
-
(1990)
Microvasc Res
, vol.40
, pp. 285-291
-
-
Wakui, S.1
Furusato, M.2
Tanaka, M.3
-
123
-
-
0034467330
-
Growth factors in glioma angiogenesis: FGFs, PDGF, EGF, and TGFs
-
Dunn IF, Heese O, Black PM. Growth factors in glioma angiogenesis: FGFs, PDGF, EGF, and TGFs. J Neurooncol 2000; 50: 121-37.
-
(2000)
J Neurooncol
, vol.50
, pp. 121-137
-
-
Dunn, I.F.1
Heese, O.2
Black, P.M.3
-
124
-
-
0032548835
-
Vascular endothelial growth factor induces heparin-binding epidermal growth factor-like growth factor in vascular endothelial cells
-
Arkonac BM, Foster LC, Sibinga NE, et al. Vascular endothelial growth factor induces heparin-binding epidermal growth factor-like growth factor in vascular endothelial cells. J Biol Chem 1998; 273: 4400-5.
-
(1998)
J Biol Chem
, vol.273
, pp. 4400-4405
-
-
Arkonac, B.M.1
Foster, L.C.2
Sibinga, N.E.3
-
125
-
-
0027275476
-
Heparin-binding epidermal growth factor-like growth factor expression in cultured fetal human vascular smooth muscle cells. Induction of mRNA levels and secretion of active mitogen
-
Dluz SM, Higashiyama S, Damm D, et al. Heparin-binding epidermal growth factor-like growth factor expression in cultured fetal human vascular smooth muscle cells. Induction of mRNA levels and secretion of active mitogen. J Biol Chem 1993; 268: 18330-4.
-
(1993)
J Biol Chem
, vol.268
, pp. 18330-18334
-
-
Dluz, S.M.1
Higashiyama, S.2
Damm, D.3
-
126
-
-
27344447301
-
Neuregulin-1alpha and beta isoform expression in cardiac microvascular endothelial cells and function in cardiac myocytes in vitro
-
Cote GM, Miller TA, Lebrasseur NK, et al. Neuregulin-1alpha and beta isoform expression in cardiac microvascular endothelial cells and function in cardiac myocytes in vitro. Exp Cell Res 2005; 311: 135-46.
-
(2005)
Exp Cell Res
, vol.311
, pp. 135-146
-
-
Cote, G.M.1
Miller, T.A.2
Lebrasseur, N.K.3
-
127
-
-
1642524201
-
The N-terminal region of NTAK/neuregulin-2 isoforms has an inhibitory activity on angiogenesis
-
Nakano N, Higashiyama S, Ohmoto H, et al. The N-terminal region of NTAK/neuregulin-2 isoforms has an inhibitory activity on angiogenesis. J Biol Chem 2004; 279: 11465-70.
-
(2004)
J Biol Chem
, vol.279
, pp. 11465-70
-
-
Nakano, N.1
Higashiyama, S.2
Ohmoto, H.3
-
128
-
-
38549151667
-
Characterization of the cell membrane-associated products of the Neuregulin 4 gene
-
Hayes N, Newsam R, Baines A, et al. Characterization of the cell membrane-associated products of the Neuregulin 4 gene. Oncogene 2008; 27: 715-20.
-
(2008)
Oncogene
, vol.27
, pp. 715-720
-
-
Hayes, N.1
Newsam, R.2
Baines, A.3
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