Acute respiratory toxicity following inhalation exposure to soman in guinea pigs

Toxicology and Applied Pharmacology

Volumn 245, Issue 2, 2010, Pages 171-178

  Perkins, Michael W ^a   Pierre, Zdenka ^a   Rezk, Peter ^a   Sabnekar, Praveena ^a   Kabra, Kareem ^b   Chanda, Soma ^b   Oguntayo, Samuel ^b   Sciuto, Alfred M ^a   Doctor, Bhupendra P ^b   Nambiar, Madhusoodana P ^b,c  

^a US ARMY MEDICAL RESEARCH INSTITUTE OF CHEMICAL DEFENSE   (United States)

^b WALTER REED ARMY INSTITUTE OF RESEARCH   (United States)

^c Uniformed Services University of the Health Sciences and the Walter Reed National Military Medical Center   (United States)

Author keywords

Central nervous system; Chemical warfare; Cholinesterases; Inhalation exposure; Nerve agents; Neuroprotection; Organophosphates; Respiratory toxicity

Indexed keywords

ACETYLCHOLINESTERASE; CHEMICAL WARFARE AGENT; CHOLINESTERASE; SODIUM CHLORIDE; SOMAN;

ACUTE TOXICITY; ANIMAL EXPERIMENT; ARTICLE; BLOOD OXYGEN TENSION; CONTROLLED STUDY; DEATH; ENZYME ACTIVITY; ENZYME BLOOD LEVEL; EXPOSURE; GUINEA PIG; LEUKOCYTE DIFFERENTIAL COUNT; LUNG INJURY; LUNG LAVAGE; LUNG TOXICITY; LYMPHOCYTE COUNT; MALE; NEUTROPHIL COUNT; NONHUMAN; PULSE RATE; SEIZURE; SURVIVAL; WEIGHT REDUCTION;

ACETYLCHOLINESTERASE; ACUTE LUNG INJURY; ANIMALS; BRONCHOALVEOLAR LAVAGE FLUID; BUTYRYLCHOLINESTERASE; CHEMICAL WARFARE AGENTS; DOSE-RESPONSE RELATIONSHIP, DRUG; GUINEA PIGS; HEART RATE; INHALATION EXPOSURE; MALE; OXYGEN; SOMAN; WEIGHT LOSS;

ANIMALIA; CAVIA;

EID: 77952889278     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2010.02.016     Document Type: Article

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