Identification of mechanisms involved in the acute airway toxicity induced by parathion

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 360, Issue 6, 1999, Pages 699-710

  Segura, Patricia ^a   Chávez, Jaime ^a   Montaño, Luis M ^a,c   Vargas, Mario H ^a   Delaunois, Annie ^b   Carbajal, Veronica ^a   Gustin, Pascal ^b  

^a INSTITUTO NACIONAL DE ENFERMEDADES RESPIRATORIAS   (Mexico)

^b UNIVERSITY OF LIÈGE   (Belgium)

^c UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

Author keywords

Acetylcholinesterase; Airway hyperresponsiveness; Bronchospasm; Cytochrome P450; Edema; Lung resistance; Organophosphate insecticide; Parathion

Indexed keywords

ACETYLCHOLINE; ACETYLCHOLINESTERASE; CYTOCHROME P450; HISTAMINE; PARATHION; SALBUTAMOL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRONCHODILATATION; BRONCHOSPASM; CONTROLLED STUDY; ENZYME INHIBITION; FEMALE; GUINEA PIG; LUNG EDEMA; LUNG MECHANICS; LUNG RESISTANCE; LUNG TOXICITY; MALE; NONHUMAN; RABBIT;

ACETYLCHOLINESTERASE; AIRWAY RESISTANCE; ALBUTEROL; ANIMALS; BODY WATER; BRONCHIAL HYPERREACTIVITY; BRONCHOALVEOLAR LAVAGE FLUID; BRONCHODILATOR AGENTS; CHOLINESTERASE INHIBITORS; CYTOCHROME P-450 ENZYME SYSTEM; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GUINEA PIGS; INSECTICIDES; LUNG; MALE; MUCUS; NERVOUS SYSTEM; PARATHION; PULMONARY EDEMA; RABBITS; RESPIRATORY MECHANICS; SEX FACTORS; TIME FACTORS;

EID: 0033385104     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002109900101     Document Type: Article

References (43)

1. Abbrecht PH, Kyle RR, Bryant HJ (1989) Pulmonary mechanical responses to cholinestarase inhibitor. Fundam Appl Toxicol 13:593-604
2. Agarwal DK, Misra D, Agarwal S, Seth PK, Kohli JD (1982) Influence of sex hormones on parathion toxicity in rats: antiacetylcholinesterase activf parathion and paraoxon in plasma, erythrocytes and brain. J Toxicol Environ Health 9: 451-459
3. Allen DL, Pollard KR, Hughes BL, Dorato MA, Wolff RK (1995) Use of head dome system to compare i.v. methacholine-induced bronchoconstriction in conscious vs. anesthetized rhesus monkeys. J Appl Toxicol 15:13-17
4. Anderson RG, Grundström N (1987) Innervation of airway smooth muscle. Efferent mechanisms. Pharmacol Ther 32:107-129
5. Barak N, Rubinstein R, Cohen S (1997) Histamine-evoked acetylcholine release in sensitized tracheal preparation. Respir Physiol 108:181-185
6. Barnas GM, Sprung J, Kahn R, Delaney PA, Agarwal M (1995) Lung tissue and airway impedances during pulmonary edema in normal range of breathing. J Appl Physiol 78:1889-1897
7. Boat TF, Kleinerman JL (1975) Human respiratory tract secretions. 2. Effect of cholinergic and adrenergic agents on in vitro release of protein and mucous glycoprotein. Chest [Suppl] 67: 32-34
8. Burke MD, Mayer RT (1974) Ethoxyresorufin: direct fluorimetric assay of a microsomal O-dealkylation, which is preferentially inducible by 3-methylcholantrene. Drug Metab Dispos 2:583-588
9. Chand N, Nolan K, Pillar J, Lomask M, Diamantis W, Sofia RD (1993) Aeroallergen-induced dyspnea in freely moving guinea pigs: quantitative measurement by bias flow ventilated whole body plethysmograph. Allergy 48:230-235
10. Del Valle J (1967) Las intoxicaciones por plaguicidas. Manifestaciones pulmonares, clínicas y radiológicas. Gac Med Mex 97: 493-501
11. Delaunois A, Gustin P, Ansay M (1992a) Altered capillary filtration coefficient in parathion-and paraoxon-induced edema in isolated and perfusated rabbit lungs. Toxicol Appl Pharmacol 116:161-169
12. Delaunois A, Gustin P, Bloden S, Dasty J, Ansay M (1992b) Intoxication par le parathion dans une exploitation bovine. Ann Med Vet 136:137-138
13. Delaunois A, Gustin P, Segura P, Vargas MH, Ansay M (1996) Interactions between acetylcholine and substance P effects on lung mechanics in the rabbit. Fundam Clin Pharmacol 10:278-288
14. Ellman GL, Courtney KD, Andres V, Feathersone RM (1961) A new and rapid colorimetric determination of acetylcholinesterase activity. Biochem Pharmacol 7:88-95
15. Erickson DA, Goodrich MS, Lech JJ (1988) The effect of piperonyl butoxide on hepatic cytochrome P-450-dependent monooxygenase activities in rainbow trout (Salmo gairdner). Toxicol Appl Pharmacol 94:1-10
16. Frank NR, Mead J, Ferris BG (1957) The mechanical behavior of the lung in healthy elderly. J Clin Invest 36:1680-1687
17. Guengerich FP (1977) Separation and purification of multiple forms of microsomal cytochrome: different forms of cytochrome P-450 towards several compounds of environmental interest. J Biol Chem 252:3970-3979
18. Halpert J, Hammond D, Neal RA (1980) Inactivation of purified rat liver cytochrome P-450 during the metabolism of parathion (diethyl p-nitrophenyl phosphorothionate). J Biol Chem 255: 1080-1089
19. Hamelmann E, Schwarze J, Takeda K, Oshiba A, Larsen GL, Irvin CG, Gelfand EW (1997) Noninvasive measurement of airway responsiveness in allergic mice using barometric plethysmography. Am J Respir Crit Care Med 156:766-775
20. Hatch RC (1982) Poisons causing nervous stimulation of depression. In: Booth NH, McDonald LE (eds) Veterinary pharmacology and therapeutics. Iowa State University Press, Ames, pp 976-1021
21. Henoa S, Corey G (1986) Plaguicidas organofosforados y carbámicos. Centro Panamericano de Ecología Humana y Salud, Metepec
22. Kass R, Kochar G, Lippman M (1991) Adult respiratory distress syndrome from organophosphate poisoning. Am J Emerg Med 9:32-33
23. Kirkpatrick CT, Rooney PJ (1982) Contractures produced by carbamate anticholinesterases in bovine tracheal smooth muscle. Clin Exp Pharmacol Physiol 9:603-611
24. Knaak JB, Yee K, Ackerman CR, Zweig G, Fry DM, Wilson BW (1984) Percutaneous absorption and dermal dose-cholinesterase response studies with parathion and carbaryl in the rat. Toxicol Appl Pharmacol 76:252-263
25. Lekeux P, Kyavu A, Clercx C, Ansay M (1986) Pulmonary function changes induced by experimental dichlorvos toxicosis in calves. Res Vet Sci 40:318-321
26. Lerman Y, Gutman H (1988) The use of respiratory stimulants in organophosphates intoxication. Med Hypotheses 26:267-269
27. Lessire F, Gustin P, Delaunois A, Bloden S, Nemmar A, Vargas M, Ansay M (1996) Relationship between parathion and paraoxon toxicokinetics, lung metabolic activity, and cholinesterase inhibition in guinea pig and rabbit lungs. Toxicol Appl Pharmacol 138:201-210
28. Mayer BW, Schlackman N (1975) Organophosphates, a pediatric hazard. Am Fam Physician 11:121-124
29. Murali MP, Huang SH, Yang CM, Dwyer TM, Farley JM (1988) Contractile responses of tracheal smooth muscle in organophosphate-treated swine. 1. Agonist changes. J Auton Pharmacol 8:93-106
30. Neal RA (1971) Enzymic mechanism of metabolism of the phosphorothionate insecticides. Arch Intern Med 128:118-124
31. Neal RA (1972) A comparison of the in vitro metabolism of parathion in the lung and liver of the rabbit. Toxicol Appl Pharmacol 23:123-130
32. Pauluhn J, Machemer L, Kimmerle G (1987) Effects of inhaled cholinesterase inhibitors on bronchial tonus and on plasma and erythrocyte acetylcholine esterase activity in rats. Toxicology 46:177-190
33. Rimington C (1940) Method of determination of sugars. Biochem J 34:931-933
34. Rubinstein R, Cohen S (1985) Histamine mediated acetylcholine release in the guinea-pig ileum. Eur J Pharmacol 111:245-250
35. Shore S, Irvin CG, Shenkier T, Martin JG (1983) Mechanism of histamine-induced contraction of canine airway smooth muscle. J Appl Phisiol 55:22-26
36. Sommer B, Montaño LM, Chávez J, Gustin P, Vargas MH (1998) Guinea pig lung resistance shows circadian rhythmicity not influenced by ozone. Respir Physiol 113:223-229
37. Taylor P (1985) Anticholinesterase agents. In: Goodman A, Goodman LS, Rall TW, Murad F (eds) The pharmacological basis of therapeutics, 7th edn. MacMillan, New York, pp 100-119
38. United States Geological Survey (1992) Pesticide National Synthesis Project: 1992 annual use. Downloadable file at URL: http://water.wr.usgs.gov
39. Vargas MH, Montaño LM, Selman M (1991a) Clasificación y patogénesis. In: Pacheco CR, Díaz GS (eds) Asma. UNAM, México, pp 51-108
40. Vargas MH, Selman M, Campos G, Montaño LM (1991b) Role of leukotriene C4 and edema in the acute allergic bronchoconstriction in the guinea pig. Arch Invest Med (Mex) 22:143-149
41. Vargas MH, Segura P, Campos MG, Hong E, Montaño LM (1994) Effect of ozone exposure on antigen-induced airway hyperresponsiveness in guinea pigs. J Toxicol Environ Health 42:435-442
42. World Health Organization: Oficina Sanitaria Panamericana (1993) Plaguicidas y salud en las Américas. Serie Ambiental 12, Washington, DC
43. 2-mediated augmentation. Am J Physiol 12: L368-L373