메뉴 건너뛰기




Volumn 4, Issue 1, 2010, Pages 37-44

Polymorphism of pharmaceutical molecules: Perspectives on nucleation

Author keywords

Control; Discovery; Nucleation; Pharmaceutical molecules; Polymorph

Indexed keywords


EID: 77952886875     PISSN: 16737369     EISSN: 16737474     Source Type: Journal    
DOI: 10.1007/s11705-009-0294-2     Document Type: Review
Times cited : (19)

References (41)
  • 1
    • 77952884286 scopus 로고    scopus 로고
    • An analysis on the production and sale of China's pharmaceutical industry
    • Wu H. An analysis on the production and sale of China's pharmaceutical industry. Chinese J Pharm, 2007, 38(4): A27-A34.
    • (2007) Chinese J Pharm , vol.38 , Issue.4
    • Wu, H.1
  • 2
    • 0033903829 scopus 로고    scopus 로고
    • Crystallization processes in pharmaceutical technology and drug delivery design
    • Shekunov B Y, York P. Crystallization processes in pharmaceutical technology and drug delivery design. J Cryst Growth, 2000, 211: 122-136.
    • (2000) J Cryst Growth , vol.211 , pp. 122-136
    • Shekunov, B.Y.1    York, P.2
  • 4
    • 0347765876 scopus 로고    scopus 로고
    • Crystal structures of drugs: Advances in determination, prediction and engineering
    • Datta S, Grant D J W. Crystal structures of drugs: advances in determination, prediction and engineering. Nat Rev Drug Discov, 2004, 3: 42-57.
    • (2004) Nat Rev Drug Discov , vol.3 , pp. 42-57
    • Datta, S.1    Grant, D.J.W.2
  • 5
    • 0002442971 scopus 로고
    • Certain problems of polymorphism (I)
    • Sirota N N. Certain problems of polymorphism (I). Cryst Res Technol, 1982, 17: 661-691.
    • (1982) Cryst Res Technol , vol.17 , pp. 661-691
    • Sirota, N.N.1
  • 6
    • 0023691164 scopus 로고
    • Frusemide crystal forms-solid-state and physicochemical analyses
    • Doherty C, York P. Frusemide crystal forms-solid-state and physicochemical analyses. Int J Pharm, 1988, 47: 141-155.
    • (1988) Int J Pharm , vol.47 , pp. 141-155
    • Doherty, C.1    York, P.2
  • 7
    • 72449163485 scopus 로고    scopus 로고
    • Polymorphic crystallization and transformation of the anti-viral/HIV drug stavudine
    • Lu J, Rohani S. Polymorphic crystallization and transformation of the anti-viral/HIV drug stavudine. Org Process Res Dev, 2009, 13: 1262-1268.
    • (2009) Org Process Res Dev , vol.13 , pp. 1262-1268
    • Lu, J.1    Rohani, S.2
  • 9
    • 0037723973 scopus 로고    scopus 로고
    • Quality evaluation of generic drugs by dissolution test: Changing the USP dissolution medium to distinguish between active and non-active mebendazole polymorphs
    • Swanepoel E, Liebenberg W, de Villiers MM. Quality evaluation of generic drugs by dissolution test: changing the USP dissolution medium to distinguish between active and non-active mebendazole polymorphs. Eur J Pharm Biopharm, 2003, 55: 345-349.
    • (2003) Eur J Pharm Biopharm , vol.55 , pp. 345-349
    • Swanepoel, E.1    Liebenberg, W.2    de Villiers, M.M.3
  • 10
    • 0034962361 scopus 로고    scopus 로고
    • Influence of crystal structure on the tableting properties of sulfamerazine polymorphs
    • Sun C, Grant D J W. Influence of crystal structure on the tableting properties of sulfamerazine polymorphs. Pharm Res, 2001, 18: 274-280.
    • (2001) Pharm Res , vol.18 , pp. 274-280
    • Sun, C.1    Grant, D.J.W.2
  • 11
    • 23844474036 scopus 로고    scopus 로고
    • An approach to solvent screening for crystallization of polymorphic pharmaceuticals and fine chemicals
    • Mirmehrabi M, Rohani S. An approach to solvent screening for crystallization of polymorphic pharmaceuticals and fine chemicals. J Pharm Sci, 2005, 94: 1560-1576.
    • (2005) J Pharm Sci , vol.94 , pp. 1560-1576
    • Mirmehrabi, M.1    Rohani, S.2
  • 12
    • 34250863849 scopus 로고    scopus 로고
    • Cocrystal or salt: Does it really matter?
    • Aakeroy C B, Fasulo M E, Desper J. Cocrystal or salt: does it really matter? Mol Pharm, 2007, 4: 317-322.
    • (2007) Mol Pharm , vol.4 , pp. 317-322
    • Aakeroy, C.B.1    Fasulo, M.E.2    Desper, J.3
  • 13
    • 65349091979 scopus 로고    scopus 로고
    • Dimorphs of a 1:1 cocrystal of ethenzamide and saccharin: Solid-state grinding methods result in metastable polymorph
    • Aitipamula S, Chow P S, Tan R B H. Dimorphs of a 1: 1 cocrystal of ethenzamide and saccharin: solid-state grinding methods result in metastable polymorph. Cryst Eng Comm, 2009, 11: 889-895.
    • (2009) Cryst Eng Comm , vol.11 , pp. 889-895
    • Aitipamula, S.1    Chow, P.S.2    Tan, R.B.H.3
  • 14
    • 33947093788 scopus 로고
    • Conformational polymorphism-the influence of crystal structure on molecular conformation
    • Bernstein J, Hagler A T. Conformational polymorphism-the influence of crystal structure on molecular conformation. J Am Chem Soc, 1978, 100: 673-681.
    • (1978) J Am Chem Soc , vol.100 , pp. 673-681
    • Bernstein, J.1    Hagler, A.T.2
  • 16
    • 25444456397 scopus 로고    scopus 로고
    • Effect of supersaturation on the crystallization of phenylbutazone polymorphs
    • Datta S, Grant D J W. Effect of supersaturation on the crystallization of phenylbutazone polymorphs. Cryst Res Technol, 2005, 40: 233-242.
    • (2005) Cryst Res Technol , vol.40 , pp. 233-242
    • Datta, S.1    Grant, D.J.W.2
  • 17
    • 4544245875 scopus 로고    scopus 로고
    • Polymorphism and crystallization of paminobenzoic acid
    • Gracin S, Rasmuson Å C. Polymorphism and crystallization of paminobenzoic acid. Cryst Growth Des, 2004, 4: 1013-1023.
    • (2004) Cryst Growth Des , vol.4 , pp. 1013-1023
    • Gracin, S.1    Rasmuson, A.C.C.2
  • 18
    • 0035157406 scopus 로고    scopus 로고
    • Polymorph screening: Influence of solvents on the rate of solvent-mediated polymorphic transformation
    • Gu C H, Young V, Grant D J W. Polymorph screening: influence of solvents on the rate of solvent-mediated polymorphic transformation. J Pharm Sci, 2001, 90: 1878-1890.
    • (2001) J Pharm Sci , vol.90 , pp. 1878-1890
    • Gu, C.H.1    Young, V.2    Grant, D.J.W.3
  • 19
    • 0037269133 scopus 로고    scopus 로고
    • Toward stereochentical control, monitoring, and understanding of crystal nucleation
    • Weissbuch I, Lahav M, Leiserowitz L. Toward stereochentical control, monitoring, and understanding of crystal nucleation. Cryst Growth Des, 2002, 3: 125-150.
    • (2002) Cryst Growth Des , vol.3 , pp. 125-150
    • Weissbuch, I.1    Lahav, M.2    Leiserowitz, L.3
  • 21
    • 0027642740 scopus 로고
    • Crystallization of polymorphs-the effect of solvent
    • Khoshkhoo S, Anwar J. Crystallization of polymorphs-the effect of solvent. J Phys D-Appl Phys, 1993, 26: B90-B93.
    • (1993) J Phys D-Appl Phys , vol.26
    • Khoshkhoo, S.1    Anwar, J.2
  • 22
    • 37549055736 scopus 로고    scopus 로고
    • Cross-nucleation between D-mannitol polymorphs in seeded crystallization
    • Tao J, Jones K J, Yu L. Cross-nucleation between D-mannitol polymorphs in seeded crystallization. Cryst Growth Des, 2007, 7: 2410-2414.
    • (2007) Cryst Growth Des , vol.7 , pp. 2410-2414
    • Tao, J.1    Jones, K.J.2    Yu, L.3
  • 23
    • 0035600053 scopus 로고    scopus 로고
    • Crystallization of the stable polymorph of hydroxytriendione: Seeding process and effects of purity
    • Beckmann W, Otto W, Budde U. Crystallization of the stable polymorph of hydroxytriendione: seeding process and effects of purity. Org Process Res Dev, 2001, 5: 387-392.
    • (2001) Org Process Res Dev , vol.5 , pp. 387-392
    • Beckmann, W.1    Otto, W.2    Budde, U.3
  • 24
    • 0036127750 scopus 로고    scopus 로고
    • The effect of amphiphilic additives on the growth and morphology of aspergillus niger acid proteinase a crystals
    • Tanaka S, Ataka M, Kubota T, Soga T, Homma K, Lee W C, Tanokura M. The effect of amphiphilic additives on the growth and morphology of aspergillus niger acid proteinase a crystals. J Cryst Growth, 2002, 234: 247-254.
    • (2002) J Cryst Growth , vol.234 , pp. 247-254
    • Tanaka, S.1    Ataka, M.2    Kubota, T.3    Soga, T.4    Homma, K.5    Lee, W.C.6    Tanokura, M.7
  • 26
    • 38449094395 scopus 로고    scopus 로고
    • Formation and solid-state characterization of a salt-induced metastable polymorph of flufenamic acid
    • Lee E H, Boerrigter S X M, Rumondor A C F, Chamarthy S P, Byrn S R. Formation and solid-state characterization of a salt-induced metastable polymorph of flufenamic acid. Cryst Growth Des, 2008, 8: 91-97.
    • (2008) Cryst Growth Des , vol.8 , pp. 91-97
    • Lee, E.H.1    Boerrigter, S.X.M.2    Rumondor, A.C.F.3    Chamarthy, S.P.4    Byrn, S.R.5
  • 27
    • 37849050589 scopus 로고    scopus 로고
    • Effect of sodium chloride on the nucleation and polymorphic transformation of glycine
    • Yang X, Lu J, Wang X J, Ching C B. Effect of sodium chloride on the nucleation and polymorphic transformation of glycine. J Cryst Growth, 2008, 310: 604-611.
    • (2008) J Cryst Growth , vol.310 , pp. 604-611
    • Yang, X.1    Lu, J.2    Wang, X.J.3    Ching, C.B.4
  • 28
    • 0037132641 scopus 로고    scopus 로고
    • The use of polymer heteronuclei for crystalline polymorph selection
    • Lang M D, Grzesiak A L, Matzger A J. The use of polymer heteronuclei for crystalline polymorph selection. J Am Chem Soc, 2002, 124: 14834-14835.
    • (2002) J Am Chem Soc , vol.124 , pp. 14834-14835
    • Lang, M.D.1    Grzesiak, A.L.2    Matzger, A.J.3
  • 29
    • 85006900123 scopus 로고
    • Selective nucleation and growth of an organic polymorph by ledge-directed epitaxy on a molecular-crystal substrate
    • Bonafede S J, Ward M D. Selective nucleation and growth of an organic polymorph by ledge-directed epitaxy on a molecular-crystal substrate. J Am Chem Soc, 1995, 117: 7853-7861.
    • (1995) J Am Chem Soc , vol.117 , pp. 7853-7861
    • Bonafede, S.J.1    Ward, M.D.2
  • 30
    • 11144249461 scopus 로고    scopus 로고
    • Selective growth of a less stable polymorph of 2-iodo-4-nitroaniline on a self-assembled monolayer template
    • Hiremath R, Varney SW, Swift J A. Selective growth of a less stable polymorph of 2-iodo-4-nitroaniline on a self-assembled monolayer template. Chem Commun, 2004, 2676-2677.
    • (2004) Chem Commun , pp. 2676-2677
    • Hiremath, R.1    Varney, S.W.2    Swift, J.A.3
  • 31
    • 34249070071 scopus 로고    scopus 로고
    • Controlling polymorphism by crystallization on self-assembled multilayers
    • Dressler D H, Mastai Y. Controlling polymorphism by crystallization on self-assembled multilayers. Cryst Growth Des, 2007, 126: 847-850.
    • (2007) Cryst Growth Des , vol.126 , pp. 847-850
    • Dressler, D.H.1    Mastai, Y.2
  • 32
    • 1642306501 scopus 로고    scopus 로고
    • Polymorph selectivity under nanoscopic confinement
    • Ha J M, Wolf J H, Hillmyer M A, Ward M D. Polymorph selectivity under nanoscopic confinement. J Am Chem Soc, 2004, 126: 3382-3383.
    • (2004) J Am Chem Soc , vol.126 , pp. 3382-3383
    • Ha, J.M.1    Wolf, J.H.2    Hillmyer, M.A.3    Ward, M.D.4
  • 33
    • 4243661500 scopus 로고    scopus 로고
    • Nonphotochemical, polarization-dependent, laser-induced nucleation in supersaturated aqueous urea solutions
    • Garetz B A, Aber J E, Goddard N L, Young R G, Myerson A S. Nonphotochemical, polarization-dependent, laser-induced nucleation in supersaturated aqueous urea solutions. Phys Rev Lett, 1996, 77: 3475-3476.
    • (1996) Phys Rev Lett , vol.77 , pp. 3475-3476
    • Garetz, B.A.1    Aber, J.E.2    Goddard, N.L.3    Young, R.G.4    Myerson, A.S.5
  • 34
    • 0011463742 scopus 로고    scopus 로고
    • Nonphotochemical, laser-induced nucleation of supersaturated aqueous glycine produces unexpected gamma-polymorph
    • Zaccaro J, Matic J, Myerson A S, Garetz B A. Nonphotochemical, laser-induced nucleation of supersaturated aqueous glycine produces unexpected gamma-polymorph. Cryst Growth Des, 2001, 1: 5-8.
    • (2001) Cryst Growth Des , vol.1 , pp. 5-8
    • Zaccaro, J.1    Matic, J.2    Myerson, A.S.3    Garetz, B.A.4
  • 35
    • 40649102167 scopus 로고    scopus 로고
    • Polymorph control: Past, present and future
    • Llinàs A, Goodman J M. Polymorph control: past, present and future. Drug Discov Today, 2008, 13(5-6): 198-210.
    • (2008) Drug Discov Today , vol.13 , Issue.5-6 , pp. 198-210
    • Llinàs, A.1    Goodman, J.M.2
  • 36
    • 33947507675 scopus 로고    scopus 로고
    • Selective glycine polymorph crystallization by using microporous membranes
    • Di Profio G, Tucci S, Curcio E, Drioli E. Selective glycine polymorph crystallization by using microporous membranes. Cryst Growth Des, 2007, 7: 526-530.
    • (2007) Cryst Growth Des , vol.7 , pp. 526-530
    • Di Profio, G.1    Tucci, S.2    Curcio, E.3    Drioli, E.4
  • 37
    • 38149018360 scopus 로고    scopus 로고
    • Influence of the roughness, topography and physicochemical properties of chemically modified surfaces on the heterogeneous nucleation of protein crystals
    • Liu Y X, Wang X J, Lu J, Ching C B. Influence of the roughness, topography and physicochemical properties of chemically modified surfaces on the heterogeneous nucleation of protein crystals. J Phys Chem B, 2007, 111(50): 13971-13978.
    • (2007) J Phys Chem B , vol.111 , Issue.50 , pp. 13971-13978
    • Liu, Y.X.1    Wang, X.J.2    Lu, J.3    Ching, C.B.4
  • 39
    • 65649125667 scopus 로고    scopus 로고
    • Polymorphism and crystallization of active pharmaceutical ingredients (APIs)
    • Lu J, Rohani S, Polymorphism and crystallization of active pharmaceutical ingredients (APIs). Curr Med Chem, 2009, 16: 884-905.
    • (2009) Curr Med Chem , vol.16 , pp. 884-905
    • Lu, J.1    Rohani, S.2
  • 40
    • 2742517055 scopus 로고    scopus 로고
    • Computer simulations of organic solids and their liquid-state precursors
    • Gavezzotti A. Computer simulations of organic solids and their liquid-state precursors. Faraday Discuss, 1997, 106: 63-77.
    • (1997) Faraday Discuss , vol.106 , pp. 63-77
    • Gavezzotti, A.1
  • 41
    • 79955037244 scopus 로고    scopus 로고
    • Ten years of experience in polymorph prediction: What next?
    • Gavezzotti A. Ten years of experience in polymorph prediction: what next? Cryst Eng Comm, 2002, 4: 343-347.
    • (2002) Cryst Eng Comm , vol.4 , pp. 343-347
    • Gavezzotti, A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.