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Volumn 19, Issue 1, 2010, Pages 1-20

Updating the model definition of the gene in the modern genomic era with implications for instruction

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EID: 77952881012     PISSN: 09267220     EISSN: 15731901     Source Type: Journal    
DOI: 10.1007/s11191-008-9161-7     Document Type: Article
Times cited : (18)

References (40)
  • 1
    • 77952883805 scopus 로고    scopus 로고
    • The current revolution in definition of the term gene
    • Authors, (submitted)
    • Authors (2007) The current revolution in definition of the term gene. Am Biol Teach (submitted).
    • (2007) Am Biol Teach
  • 2
    • 0346434985 scopus 로고    scopus 로고
    • Alberts B, Johnson A, Lewis J et al (eds), 4th edn. Garland Science, New York
    • Alberts B, Johnson A, Lewis J et al (eds) (2002) Molecular biology of the cell, 4th edn. Garland Science, New York.
    • (2002) Molecular biology of the cell
  • 3
    • 0034342037 scopus 로고    scopus 로고
    • Teaching genetics at secondary school: A strategy for teaching about the location of inheritance information
    • doi:10.1002/(SICI)1098-237X(200005)84:3<313::AID-SCE2>3.0.CO;2-N
    • Banet E, Ayuso E (2000) Teaching genetics at secondary school: a strategy for teaching about the location of inheritance information. Sci Educ 84: 313-351. doi: 10. 1002/(SICI)1098-237X(200005)84: 3<313:: AID-SCE2> 3. 0. CO; 2-N.
    • (2000) Sci Educ , vol.84 , pp. 313-351
    • Banet, E.1    Ayuso, E.2
  • 4
    • 0002125637 scopus 로고
    • The elementary units of heredity
    • W. D. McElroy and B. Glass (Eds.), Baltimore: Johns Hopkins Press
    • Benzer S (1957) The elementary units of heredity. In: McElroy WD, Glass B (eds) The chemical basis of heredity. Johns Hopkins Press, Baltimore, pp 70-93.
    • (1957) The Chemical Basis of Heredity , pp. 70-93
    • Benzer, S.1
  • 5
    • 56249106601 scopus 로고    scopus 로고
    • A unified view of the gene, or how to overcome reductionism
    • P. Beurton, R. Falk, and H.-J. Rheinberger (Eds.), Cambridge: Cambridge University Press
    • Beurton P (2000) A unified view of the gene, or how to overcome reductionism. In: Beurton P, Falk R, Rheinberger H-J (eds) The concept of the gene in development and evolution: historical and epistemological perspectives. Cambridge University Press, Cambridge, pp 286-314.
    • (2000) The Concept of the Gene in Development and Evolution: Historical and Epistemological Perspectives , pp. 286-314
    • Beurton, P.1
  • 6
    • 34250305146 scopus 로고    scopus 로고
    • Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project
    • ENCODE Project Consortium
    • ENCODE Project Consortium, Birney E, Stamatoyannopoulos JA et al (2007) Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature 14: 799-816.
    • (2007) Nature , vol.14 , pp. 799-816
    • Birney, E.1    Stamatoyannopoulos, J.A.2
  • 9
    • 0037354687 scopus 로고    scopus 로고
    • Teaching 'biological identity' as genome/environment interactions
    • Forissier T, Clement P (2003) Teaching 'biological identity' as genome/environment interactions. J Biol Educ 37: 85-90.
    • (2003) J Biol Educ , vol.37 , pp. 85-90
    • Forissier, T.1    Clement, P.2
  • 10
    • 84946576872 scopus 로고    scopus 로고
    • Gene, Available at, Cited 6 May 2008
    • Gene (2004) Stanford encyclopedia of philosophy. Available at http://plato. stanford. edu/entries/gene/. Cited 6 May 2008.
    • (2004) Stanford encyclopedia of philosophy
  • 11
    • 34250196839 scopus 로고    scopus 로고
    • Definition of historical models of gene function and their relation to students' understanding of genetics
    • doi:10.1007/s11191-006-9064-4
    • Gericke NM, Hagberg M (2007) Definition of historical models of gene function and their relation to students' understanding of genetics. Sci & Educ 16: 849-881. doi: 10. 1007/s11191-006-9064-4.
    • (2007) Sci & Educ , vol.16 , pp. 849-881
    • Gericke, N.M.1    Hagberg, M.2
  • 12
    • 34250330777 scopus 로고    scopus 로고
    • What is a gene, post-ENCODE? History and updated definitions
    • doi:10.1101/gr.6339607
    • Gerstein MB, Bruce C, Rozowsky JS et al (2007) What is a gene, post-ENCODE? History and updated definitions. Genome Res 17: 669-681. doi: 10. 1101/gr. 6339607.
    • (2007) Genome Res , vol.17 , pp. 669-681
    • Gerstein, M.B.1    Bruce, C.2    Rozowsky, J.S.3
  • 13
    • 33745008608 scopus 로고    scopus 로고
    • The DNA sequence and biological annotation of human chromosome 1
    • Erratum in Nature 443:1013, doi:10.1038/nature04727
    • Gregory SG, Barlow KF, McLay KE et al (2006) The DNA sequence and biological annotation of human chromosome 1. Nature 441: 315-321. Erratum in Nature 443: 1013. doi: 10. 1038/nature04727.
    • (2006) Nature , vol.441 , pp. 315-321
    • Gregory, S.G.1    Barlow, K.F.2    McLay, K.E.3
  • 14
    • 84920056771 scopus 로고
    • The significance of pneumococcal types
    • Griffith F (1928) The significance of pneumococcal types. J Hyg Camb 27: 113-159.
    • (1928) J Hyg Camb , vol.27 , pp. 113-159
    • Griffith, F.1
  • 15
    • 0002610948 scopus 로고
    • Independent functions of viral protein and nucleic acid in growth of bacteriophage
    • doi:10.1085/jgp. 36.1.39
    • Hershey AD, Chase M (1952) Independent functions of viral protein and nucleic acid in growth of bacteriophage. J Gen Physiol 36: 39-56. doi: 10. 1085/jgp. 36. 1. 39.
    • (1952) J Gen Physiol , vol.36 , pp. 39-56
    • Hershey, A.D.1    Chase, M.2
  • 16
    • 1842337282 scopus 로고
    • Gene mutations in human haemoglobin: The chemical difference between normal and sickle cell haemoglobin
    • doi:10.1038/180326a0
    • Ingram VM (1957) Gene mutations in human haemoglobin: the chemical difference between normal and sickle cell haemoglobin. Nature 180: 326-328. doi: 10. 1038/180326a0.
    • (1957) Nature , vol.180 , pp. 326-328
    • Ingram, V.M.1
  • 17
    • 7244245762 scopus 로고    scopus 로고
    • Finishing the euchromatic sequence of the human genome
    • International Human Genome Sequencing Consortium, doi:10.1038/nature03001
    • International Human Genome Sequencing Consortium (2004) Finishing the euchromatic sequence of the human genome. Nature 431: 931-945. doi: 10. 1038/nature03001.
    • (2004) Nature , vol.431 , pp. 931-945
  • 18
    • 54249116230 scopus 로고
    • Genetic regulatory mechanisms in the synthesis of proteins
    • Jacob F, Monod J (1961) Genetic regulatory mechanisms in the synthesis of proteins. J Mol Biol 3: 318-356.
    • (1961) J Mol Biol , vol.3 , pp. 318-356
    • Jacob, F.1    Monod, J.2
  • 21
    • 2042437650 scopus 로고    scopus 로고
    • Initial sequencing and analysis of the human genome
    • Errata in Nature 411:720 and in Nature 412:565
    • Lander ES, Linton LM, Birren B et al (2001) Initial sequencing and analysis of the human genome. Nature 409: 860-921. Errata in Nature 411: 720 and in Nature 412: 565.
    • (2001) Nature , vol.409 , pp. 860-921
    • Lander, E.S.1    Linton, L.M.2    Birren, B.3
  • 22
    • 1242277306 scopus 로고    scopus 로고
    • Traits, genes, particles and information: Re-visiting students' understandings of genetics. Research report
    • doi:10.1080/0950069032000072782
    • Lewis J, Kattmann U (2004) Traits, genes, particles and information: re-visiting students' understandings of genetics. Research report. Int J Sci Educ 26: 195-206. doi: 10. 1080/0950069032000072782.
    • (2004) Int J Sci Educ , vol.26 , pp. 195-206
    • Lewis, J.1    Kattmann, U.2
  • 23
    • 0033999237 scopus 로고    scopus 로고
    • All in the genes?-young people's understanding of the nature of genes
    • Lewis J, Leach J, Wood-Robinson C (2000a) All in the genes?-young people's understanding of the nature of genes. J Biol Educ 34: 74-79.
    • (2000) J Biol Educ , vol.34 , pp. 74-79
    • Lewis, J.1    Leach, J.2    Wood-Robinson, C.3
  • 24
    • 0034414427 scopus 로고    scopus 로고
    • Chromosomes: The missing link-young people's understanding of mitosis, meiosis, and fertilisation
    • Lewis J, Leach J, Wood-Robinson C (2000b) Chromosomes: the missing link-young people's understanding of mitosis, meiosis, and fertilisation. J Biol Educ 34: 189-199.
    • (2000) J Biol Educ , vol.34 , pp. 189-199
    • Lewis, J.1    Leach, J.2    Wood-Robinson, C.3
  • 25
    • 0041985452 scopus 로고    scopus 로고
    • Genes, chromosomes, cell division and inheritance-do students see any relationship?
    • doi:10.1080/095006900289949
    • Lewis J, Wood-Robinson C (2000) Genes, chromosomes, cell division and inheritance-do students see any relationship? Int J Sci Educ 22: 177-195. doi: 10. 1080/095006900289949.
    • (2000) Int J Sci Educ , vol.22 , pp. 177-195
    • Lewis, J.1    Wood-Robinson, C.2
  • 26
    • 0035597468 scopus 로고    scopus 로고
    • Attempting to break the code in student comprehension of genetic concepts
    • Marbach-Ad G (2001) Attempting to break the code in student comprehension of genetic concepts. J Biol Educ 35: 183-189.
    • (2001) J Biol Educ , vol.35 , pp. 183-189
    • Marbach-Ad, G.1
  • 27
    • 0034378275 scopus 로고    scopus 로고
    • Students' cellular and molecular explanations of genetic phenomena
    • Marbach-Ad G, Stavy R (2000) Students' cellular and molecular explanations of genetic phenomena. J Biol Educ 34: 200-205.
    • (2000) J Biol Educ , vol.34 , pp. 200-205
    • Marbach-Ad, G.1    Stavy, R.2
  • 28
    • 0002805901 scopus 로고    scopus 로고
    • Metaphorical reasoning about genetics
    • doi:10.1080/0950069970190104
    • Martins I, Ogborn J (1997) Metaphorical reasoning about genetics. Int J Sci Educ 19: 47-63. doi: 10. 1080/0950069970190104.
    • (1997) Int J Sci Educ , vol.19 , pp. 47-63
    • Martins, I.1    Ogborn, J.2
  • 29
    • 33747830026 scopus 로고
    • Artificial transmutation of the gene
    • doi:10.1126/science.66.1699.84
    • Muller HJ (1927) Artificial transmutation of the gene. Science 66: 84-87. doi: 10. 1126/science. 66. 1699. 84.
    • (1927) Science , vol.66 , pp. 84-87
    • Muller, H.J.1
  • 30
    • 77952879536 scopus 로고
    • Special issue on concept mapping
    • Novak JD, Wandersee J (eds)
    • Novak JD, Wandersee J (eds) (1991) Special issue on concept mapping. J Res Sci Teach 28.
    • (1991) J Res Sci Teach , pp. 28
  • 31
    • 0014685074 scopus 로고
    • The haemoglobin molecule. The Croonian lecture
    • Perutz MF (1969) The haemoglobin molecule. The Croonian lecture. Proc R Soc Lond B Biol Sci 173: 113-140.
    • (1969) Proc R Soc Lond B Biol Sci , vol.173 , pp. 113-140
    • Perutz, M.F.1
  • 32
    • 1042309254 scopus 로고    scopus 로고
    • Gene concepts: Fragments from the perspective of molecular biology
    • P. Beurton, R. Falk, and H.-J. Rheinberger (Eds.), Cambridge: Cambridge University Press
    • Rheinberger H-J (2000) Gene concepts: fragments from the perspective of molecular biology. In: Beurton P, Falk R, Rheinberger H-J (eds) The concept of the gene in development and evolution: historical and epistemological perspectives. Cambridge University Press, Cambridge, pp 219-239.
    • (2000) The Concept of the Gene in Development and Evolution: Historical and Epistemological Perspectives , pp. 219-239
    • Rheinberger, H.-J.1
  • 33
    • 0037432747 scopus 로고    scopus 로고
    • Genomics. Defining genes in the genomics era
    • doi:10.1126/science.1084354
    • Snyder M, Gerstein M (2003) Genomics. Defining genes in the genomics era. Science 300: 258-260. doi: 10. 1126/science. 1084354.
    • (2003) Science , vol.300 , pp. 258-260
    • Snyder, M.1    Gerstein, M.2
  • 35
    • 0024591610 scopus 로고
    • An erythroid-specific, developmental-stage-independent enhancer far upstream of the human "beta-like globin" genes
    • doi:10.1073/pnas.86.8.2554
    • Tuan DY, Solomon WB, London IM, Lee DP (1989) An erythroid-specific, developmental-stage-independent enhancer far upstream of the human "beta-like globin" genes. Proc Natl Acad Sci USA 86: 2554-2558. doi: 10. 1073/pnas. 86. 8. 2554.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 2554-2558
    • Tuan, D.Y.1    Solomon, W.B.2    London, I.M.3    Lee, D.P.4
  • 36
    • 0035895505 scopus 로고    scopus 로고
    • The sequence of the human genome
    • Erratum in Science 292:1838, doi:10.1126/science.1058040
    • Venter JC, Adams MD, Myers EW et al (2001) The sequence of the human genome. Science 291: 1304-1351. Erratum in Science 292: 1838. doi: 10. 1126/science. 1058040.
    • (2001) Science , vol.291 , pp. 1304-1351
    • Venter, J.C.1    Adams, M.D.2    Myers, E.W.3
  • 37
    • 0002121943 scopus 로고    scopus 로고
    • Exploring conceptual change in genetics using a multidimensional interpretive framework
    • doi:10.1002/(SICI)1098-2736(199811)35:9<1031::AID-TEA5>3.0.CO;2-E
    • Venville G, Treagust D (1998) Exploring conceptual change in genetics using a multidimensional interpretive framework. J Res Sci Teach 35: 1031-1055. doi: 10. 1002/(SICI)1098-2736(199811)35: 9<1031:: AID-TEA5> 3. 0. CO; 2-E.
    • (1998) J Res Sci Teach , vol.35 , pp. 1031-1055
    • Venville, G.1    Treagust, D.2
  • 38
    • 2442629856 scopus 로고    scopus 로고
    • Gene sweepstakes ends, but winner may well be wrong
    • June 3 Section F, Available at, Cited 10 Dec 2007
    • Wade N (2003) Gene sweepstakes ends, but winner may well be wrong. New York Times June 3 Section F: 1. Available at http://query. nytimes. com/gst/fullpage. html?res=9A02E0D81230F930A35755C0A9659C8B63. Cited 10 Dec 2007.
    • (2003) New York Times , pp. 1
    • Wade, N.1
  • 39
    • 0038497542 scopus 로고
    • Molecular structure of nucleic acids; a structure for deoxyribose nucleic acid
    • doi:10.1038/171737a0
    • Watson JD, Crick FH (1953) Molecular structure of nucleic acids; a structure for deoxyribose nucleic acid. Nature 171: 737-738. doi: 10. 1038/171737a0.
    • (1953) Nature , vol.171 , pp. 737-738
    • Watson, J.D.1    Crick, F.H.2
  • 40
    • 0002341725 scopus 로고
    • Young people's ideas about inheritance and evolution
    • doi:10.1080/03057269408560038
    • Wood-Robinson C (1994) Young people's ideas about inheritance and evolution. Stud Sci Educ 24: 29-47. doi: 10. 1080/03057269408560038.
    • (1994) Stud Sci Educ , vol.24 , pp. 29-47
    • Wood-Robinson, C.1


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