Genomics: Defining genes in the genomics era

Science

Volumn 300, Issue 5617, 2003, Pages 258-260

  Snyder, Michael ^a   Gerstein, Mark ^a  

^a YALE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GENOME;

GENE INACTIVATION; GENETIC SELECTION; GENETIC TRANSCRIPTION; GENOMICS; MOLECULAR INTERACTION; OPEN READING FRAME; PRIORITY JOURNAL; REVIEW;

ALTERNATIVE SPLICING; BASE SEQUENCE; CONSERVED SEQUENCE; GENE SILENCING; GENES; GENOME, FUNGAL; GENOME, HUMAN; GENOMICS; HUMANS; OPEN READING FRAMES; PSEUDOGENES; SACCHAROMYCES CEREVISIAE; TRANSCRIPTION, GENETIC;

EID: 0037432747     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1084354     Document Type: Review

References (30)

1. M. Morange, The Misunderstood Gene (Harvard Univ. Press, Cambridge, MA, 2001).
2. R. Falk, Stud. Hist. Philos. Sci. 17, 133 (1986).
3. S. Eddy, Cell 109, 137 (2002).
4. C. Burge, S. Karlin, Curr. Opin. Struct. Biol. 8, 346 (1998).
5. M. Zhang, Nature Rev. Genet. 3, 698 (2002).
6. C. Horak, M. Snyder, Funct. Integ. Genomics 2, 171 (2002).
7. P. Brown, D. Botstein, Nature Genet. 21, 33 (1999).
8. V. Velculescu et al., Cell 88, 243 (1997).
9. A. Kumar et al., Nature Biotechnol. 20, 58 (2002).
10. P. Kapranov et al., Science 296, 916 (2002).
11. J. Rinn et al., Genes Dev. 17, 529 (2003).
12. P. Coelho et al., Curr. Opin. Microbiol. 3, 309 (2000).
13. G. Giaever et al., Nature 418, 387 (2002).
14. P. Coelho et al., Genes Dev. 16, 2755 (2002).
15. K. T. Tycowski et al., Nature 379, 464 (1996).
16. B. Modrek, C. Lee, Nature Genet. 30, 13 (2002).
17. E. Lander et al., Nature 409, 860 (2001).
18. P. Harrison, M. Gerstein, J. Mol. Biol. 318, 1155 (2002).
19. Z. Zhang et al., Genome Res. 12, 1466 (2002).
20. H. Liu et al., Genetics 144, 967 (1996).
21. P. Harrison et al., J. Mol. Biol. 316, 409 (2002).
22. H. Mewes et al., Nature 387 (suppl.), 7 (1997).
23. P. Harrison et al., Nucleic Acids Res. 30, 1083 (2002).
24. J. Venter et al., Science 291, 1304 (2001).
25. M. Das et al., Genomics 77, 71 (2001).
26. M. Kowalczuk et al., Yeast 15, 1031 (1999).
27. P. Macklewicz et al., Yeast 19, 619 (2002).
28. C. Zhang, J. Wang, Nucleic Acids Res. 28, 2804 (2000).
29. G. Blandin et al., FEBS Lett. 487, 31 (2000).
30. We thank A. Kumar, M. Vidal, S. Karlin, C. Burge, P. Harrison, Z. Zhang, M. Zhang, W. Summers, M. Cherry, R. Lifton, M. Muensterkoetter, M. Seringhaus, and A. Sali for helpful comments.