Long-chain 3-hydroxy fatty acids accumulating in LCHAD and MTP deficiencies induce oxidative stress in rat brain

Neurochemistry International

Volumn 56, Issue 8, 2010, Pages 930-936

  Tonin, Anelise M ^a   Grings, Mateus ^a   Busanello, Estela N B ^a   Moura, Alana P ^a   Ferreira, Gustavo C ^a   Viegas, Carolina M ^a   Fernandes, Carolina G ^a   Schuck, Patrícia F ^a,c   Wajner, Moacir ^a,b  

^a FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^b HOSPITAL DE CLÍNICAS DE PORTO ALEGRE   (Brazil)

^c UNIVERSIDADE DO EXTREMO SUL CATARINENSE   (Brazil)

Author keywords

Brain; LCHAD deficiency; Long chain 3 hydroxy fatty acids; Oxidative stress; Rat; Reactive species

Indexed keywords

3 HYDROXYDODECANOIC ACID; 3 HYDROXYMYRISTIC ACID; 3 HYDROXYPALMITIC ACID; ANTIOXIDANT; CARBONYL DERIVATIVE; DECANOIC ACID DERIVATIVE; DEFEROXAMINE; GLUTATHIONE; HYDROXY FATTY ACID; LONG CHAIN FATTY ACID; NITRATE; NITRITE; PALMITIC ACID DERIVATIVE; SCAVENGER; THIOBARBITURIC ACID REACTIVE SUBSTANCE; THIOL DERIVATIVE; TROLOX C; UNCLASSIFIED DRUG;

3 HYDROXYACYL COENZYME A DEHYDROGENASE DEFICIENCY; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN DAMAGE; BRAIN METABOLISM; CONTROLLED STUDY; ENZYME DEFICIENCY; IN VITRO STUDY; LIPID PEROXIDATION; MALE; MITOCHONDRIAL TRIFUNCTIONAL PROTEIN; NEUROLOGIC DISEASE; NONHUMAN; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN DEFICIENCY; RAT;

3-HYDROXYACYL COA DEHYDROGENASES; ANIMALS; BRAIN; BRAIN DISEASES, METABOLIC; DECANOIC ACIDS; FATTY ACIDS; LIPID METABOLISM DISORDERS; MALE; MULTIENZYME COMPLEXES; MYRISTIC ACIDS; OXIDATIVE STRESS; PALMITIC ACIDS; RATS; RATS, WISTAR;

RATTUS;

EID: 77952878247     PISSN: 01970186     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuint.2010.03.025     Document Type: Article

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