Pharmacological activities and chemical composition of the Olea europaea L. leaf essential oils from Tunisia

Journal of Food, Agriculture and Environment

Volumn 8, Issue 2, 2010, Pages 204-208

  Haloui, Ehsen ^a   Marzouk, Zohra ^a   Marzouk, Belsem ^a   Bouftira, Ibtissem ^a   Bouraoui, Abderrahman ^a   Fenina, Nadia ^a  

^a UNIVERSITY OF MONASTIR   (Tunisia)

Author keywords

Analgesic activity; Anti inflammatory activity; Chemical composition; cv. Chemlali; Essential oil; Olea europaea L.; Paw edema; Radical scavenging activity

Indexed keywords

1,1 DIPHENYL 2 PICRYLHYDRAZYL; 1,4 DIMETHOXYBENZENE; 2 HEXENOL; 2 METHOXY 3 ISOPROPYLPYRAZINE; 2,4 DIMETHYLDODECANE; 2,6 DIMETHYLOCTANE; 2,6 NONADIENAL; 2,6 NONADIENOL; 2,6,11 TRIMETHYLDODECANE; 3 HEXANOL; 3 HEXENYL ACETATE; ACETIC ACID; ALPHA IONONE; BETA IONONE; BETA PINENE; DECANAL; DOCOSANE; ESSENTIAL OIL; HUMULENE; LAURYL ALCOHOL; LYSINE ACETYLSALICYLATE; OLEA EUROPAEA EXTRACT; OLEIC ACID; PALMITIC ACID; PINENE; PLANT EXTRACT; TETRACOSANE; UNCLASSIFIED DRUG;

ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG IDENTIFICATION; DRUG SCREENING; FEMALE; GAS CHROMATOGRAPHY; MALE; MASS FRAGMENTOGRAPHY; MOUSE; NONHUMAN; OLIVE TREE; PAW EDEMA; PLANT LEAF; RAT; TRADITIONAL MEDICINE; TUNISIA; WRITHING TEST;

BACTERIA (MICROORGANISMS); OLEA EUROPAEA;

EID: 77952829880     PISSN: 14590255     EISSN: 14590263     Source Type: Journal    
DOI: None     Document Type: Article

References (48)

1. Khlif, M., Ayadi, M., Grati-Kammoun, N., Arous, M. N., Rekik, H., Hamdi, M. T. and Rekik-Fakhfakh, B. 2002. Identifying Chemlali olive variety in its traditional area. Acta Hortic. 586:117-120. (Pubitemid 36010420)
2. Ciafardini, G. and Zullo, B. A. 2002. Microbiological activity in stored olive oil. Int. J. Food Microbiol. 75:111-118.
3. Fernandez-Escobar, R., Moreno, R. and Garcia-Creus, M. 1999. Seasonal changes of mineral nutrients in olive leaves during the alternate-bearing cycle. Sci. Hortic. 82:25-45.
4. Gucci, R., Lombardini, L. and Tattini, M. 1997. Analysis of leaf water relations in leaves of two olive (Olea europaea) cultivars differing in tolerance to salinity. Tree Physiol. 17:13-21.
5. Boukef, M. K. 1986. Médecine traditionnelle et pharmacopée. Les plantes dans la médecine traditionnelle tunisienne. Agence de coopération culturelle et technique. Paris, 165 p.
6. Bisignano, G., Tomaino, A., Cascio, R. L., Crisafi, G., Uccella, N. and Saija, A. 1999. On the in vitro antimicrobial activity of oleuropein and hydroxytyrosol. J. Pharm. Pharmaco. 51:971-974.
7. Pereira, A. P., Ferreira, I. C., Marcelino, F., Valentao, P., Andrade, P. B., Seabra, R., Estevinho, L., Bento, A and Pereira, J. A. 2007. Phenolic compounds and antimicrobial activity of olive (Olea europaea L.cv. Cobrancosa) leaves. Molecules 12:1153-1162.
8. Markin, D., Duek, L. and Berdicevsky, I. 2003. In vitro antimicrobial activity of olive leaves. Mycoses 46:132-136.
9. Dekanski, D., Janicijevic-Hudomal, S., Tadic, V., Markovic, G., Arsic, I. and Mestrovic, D. M. 2009. Photochemical analysis and gastroprotective activity of an olive leaf extract. J. Serb. Chem. Soc. 74:367-377.
10. Benavente-Garcia, O., Castillo, J., Lorente, J., Ortuno, A. and Del Rio, J. A. 2000. Antioxidant activity of phenolics extracted from Olea europaea L. leaves. Food Chem. 68:457-462.
11. Briante, R., Febbraio, F. and Nucci, R. 2003. Antioxidant properties of low molecular weight phenols present in the Mediterranean diet. J. Agric. Food Chem. 51:6975-6981.
12. Skrget, M., Kotnik, P., Hadolin, M., Hra, A. R., Simoni, M. and Knez, Z. 2005. Phenols, proanthocyanidins, flavones and flavonols in some plant materials and their antioxidant activities. Food Chem. 89:191-198. (Pubitemid 39094550)
13. Somova, L. I., Shode, F. O., Ramnanan, P. and Nadar, A. 2003. Antihypertensive, antiatherosclerotic and antioxidant activity of triterpenoids isolated from Olea europaea, subspecies Africana leaves. J. Ethnopharmacol. 84:299-330
14. Khayyal, M. T., El-Ghazaly, M. A., Abdallah, D. M., Nassar, N. N., Okpanyi, S. N. and Kreuter, M. H. 2002. Blood pressure lowering effect of an olive leaf extract (Olea europaea) in L-NAME induced hypertension in rats. Arzneimittel-Forsch. 52:797-802.
15. Gonzalez, M., Zarzuelo, A., Gamez, M. J., Utrilla, M. P., Jimenez, J. and Osuna, I. 1992. Hypoglycemic activity of olive leaf. Planta Med. 58:513-515.
16. Al-Azzawie, H. and Alhamdani, M. S. S. 2006. Hypoglycemic and antioxidant effect of oleuropein in alloxan-diabetic rabbits. Life Sci. 78:1371-1377. (Pubitemid 43199957)
17. Somova, L. I., Shode, F. O. and Mipando, M. 2004. Cardiotonic and antidysrhythmic effects of oleanolic and ursolic acids, methyl maslinate and uvaol. Phytomedicine 11:121-129.
18. Wang, L., Geng, C., Jiang, L., Gong, G., Liu, D., Yoshimura, H. and Zhong, L. 2008. The anti-atherosclerotic effect of olive leaf extract is related to suppressed inflammatory response in rabbits with experimental atherosclerosis. Eur. J. Nut. 47:235-243.
19. Lee-Huang, S., Zhang, L., Huang, P. L. and Chang, Y. T. 2003. Anti-HIV activity of olive leaf extract (OLE) and modulation of host cell gene expression by HIV-1 infection and OLE treatment. Biochem. Biophys. Res. Commun. 307:1029-1037.
20. Micol, V., Caturla, N., Pérez-Fons, L., Más, V., Pérez, L. and Estepa, A. 2005. The olive leaf extract exhibits antiviral activity against viral haemorrhagic septicaemia rhabdovirus (VHSV). Antiviral Res. 66:129-136.
21. Hamdi, H. K. and Castellon, R. 2005. Oleuropein, a non-toxic olive iridoid, is an anti-tumor agent and cytoskeleton disruptor. Biochem. Biophys. Res. Commun. 334:769-778.
22. Abaza, L., Talorete, T. P., Yamada, P., Kurita, Y., Zarrouk, M. and Isoda, H. 2007. Induction of growth inhibition and differentiation of human leukemia HL-60 cells by a Tunisian gerboui olive leaf extract. Biosci. Biotechnol. Biochem.71:1306-1312.
23. Pieroni, A. Heimler, D. Pieters, L. van Poel, B. and Vlietinck, A. J. 1996. In vitro anti-complementary activity of flavonoids from olive (Olea europaea L.) leaves. Pharmazie 51:765.
24. Campeol, E., Flamini, G., Chericoni, S., Catalano, S. and Cremonini, R. 2001. Volatile compounds from three cultivars of Olea europaea from Italy. J. Agric. Food Chem. 49:5409-5411.
25. Campeol, E., Flamini, G., Cioni, P. L., Morelli, I., Cremonini, R. and Ceccarini, L. 2003.Volatile fractions from three cultivars of Olea europaea L. collected in two different seasons. J. Agric. Food Chem. 51:1994-1999.
26. Flamini, G., Cioni, P. L. and Morelli, P. L. 2003. Volatiles from leaves, fruits and virgin oil from Olea europaea cv. Olivastra Seggianese from Italy. J. Agric. Food Chem. 51:1382-1386.
27. Pottier-Alapetite, G. 1981. Flore de Tunisie: Angiospermes- Dicotylédones: Gamopétales. Imprimerie officielle de la République Tunisienne.
28. Adams, R. P. 2001. Identification of Essential Oils Components by Gas Chromatography/Mass Spectroscopy. Allured,Carol Stream, IL, USA.
29. th edn Database. NIST Spectra Data CD-ROM. Wiley and Sons, New York, NY.
30. 50 and its error by means of log-probit graphic paper. Proceedings of the Society of Experimental Biology and Medicine 57:261-264.
31. Koster, R., Anderson, M. and De Beer, E. J. 1959. Acetic acid for analgesic screening. Federation Proceedings 18:418-420.
32. Winter, C. A., Risley, E. A. and Nuss, G. W. 1962. Carrageenan induced edema hind paw of the rat as an essay for anti-inflammatory drugs. Proceedings of the Society for Experimental Biology and Medicine 3:544-547.
33. Cuendet, M., Hostettmann, K. and Potterat, O. 1997. Iridoid glucosides with free radical scavenging properties from Fragraea blumei. Helvetica Chim. Acta 80:1144-1152.
34. Burits, M. and Bucar, F. 2000. Antioxidant activity of Nigella sativa essential oil. Phytother. Res. 14:323-328.
35. Tepe, B., Daferera, D., Sokmen, A., Sokmen, M. and Polissiou, M. 2005. Antimicrobial and antioxidant activities of the essential oil and various extracts of Salvia tomentosa Miller (Lamiaceae). Food Chem. 90:333-340.
36. Lee, S., Umano, K., Shibamoto and Tand Lee, K. 2005. Identification of volatile components in basil (Ocimum basilicum L.) and thyme leaves (Thymus vulgaris L.) and their antioxidant properties. Food Chem. 91:131-137.
37. Lee, B. H., Choi, W. S., Lee, S. E and Park, B. S. 2001. Fumigant toxicity of essential oils and their constituent compounds towards the rice weevil, Sitophilus oryzae (L.). Crop Protection 20:317-320.
38. Sadraei, H., Ashgari, G. R., Hajhashemi, V., Kolagar, A. and Ebrahimi, M. 2001. Spasmolytic activity of essential oil and various extracts of Ferula gummosa Boiss. on ileum contractions. Phytomedicine 8:370-376.
39. Mourey, A. and Canillac, N. 2002. Anti-Listeria monocytogenes activity of essential oils components of conifers. Food Contam. 13:289-292.
40. Savelev, S., Okello, E., Perry, N. S. L., Wilkins, R. M and Perry, E. K. 2003. Synergistic and antagonistic interactions of ticholinesterase terpenoids in Salvia lavandulaefolia essential oil. Pharmacol. Biochem. Be. 75:661-668.
41. Akutsu, H., Kikusui, T., Takeuchi, Y., Sano, K., Hatanaka, A. and Mori, Y. 2000. Alleviating effects of plant-derived fragrances on stress-induced hyperthermia in rats. Physiol Behav. 75:355-360.
42. Wang, W., Wu, N., Zu, Y. G. and Fu,Y. J. 2008. Antioxidative activity of Rosmarinus officinalis L. essential oil compared to its main components. Food Chem. 108:1019-1022.
43. Kelen, M. and Tepe, B. 2008. Chemical composition, antioxidant and antimicrobial properties of the essential oils of three Salvia species from Turkish flora. Bioresource Technol. 99:4096-4104.
44. Burits, M., Asres, K. and Bucar, F. 2001. The antioxidant activity of the essential oils of Artemisia abyssinica and Juniperus procera. Phytoter. Res. 15:103-108.
45. Olajide, O. A., Makinde, M. J. and Awe, S. O. 1999. Effects of the aqueous extract of Bridelia ferruginea stem bark on carrageenan-induced oedema and granuloma tissue formation in rats and mice. J. Ethnopharmacol. 66:113-117.
46. Moulin, M. and Coquerel, A. 2002. Pharmacologie, connaissance et pratique. 2ème édn. Masson, Paris, 845 p.
47. El Tantaway, M. E., El Shakhawy, F. S., El Sohly, M. A and Ross, S. A. 1999. Chemical composition and biological activity of the essential oil of the fruit of Taxodium distichum L. Rich, growing in Egypt. J. Essent. Oil Res. 11:386-392.
48. Orhan, I., Küpeli, E., Aslan, M., Kartal, M. and Yesilada, E. 2006. Bioassay-guided evaluation of anti-inflammatory and antinociceptive activities of pistachio, Pistacia vera L. J. Ethnopharmacol. 105:235-240.