Stereoselective and multiple carrier-mediated transport of cetirizine across Caco-2 cell monolayers with potential drug interaction

Chirality

Volumn 22, Issue 7, 2010, Pages 684-692

  He, Ying ^a,b   Liu, Yao ^a   Zeng, Su ^a  

^a ZHEJIANG UNIVERSITY   (China)

^b UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

Caco 2 cells; Cetirizine; Drug interaction; Enantioselective; MRP; P gp

Indexed keywords

CEFRADINE; CETIRIZINE; CIMETIDINE; CYCLOSPORIN A; DICLOFENAC POTASSIUM; DOXORUBICIN; GLYCOPROTEIN P; INDOMETACIN; LEVOCETIRIZINE; MULTIDRUG RESISTANCE PROTEIN; PROBENECID; QUINIDINE; RANITIDINE; RHODAMINE 123; VERAPAMIL;

ARTICLE; CELL MEMBRANE PERMEABILITY; CELL MEMBRANE TRANSPORT; CELL STRAIN CACO 2; CHIRALITY; DRUG ABSORPTION; DRUG DISTRIBUTION; DRUG EXCRETION; DRUG METABOLISM; DRUG TRANSPORT; ENANTIOMER; HUMAN; HUMAN CELL; PRIORITY JOURNAL; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

ADENOSINE TRIPHOSPHATE; BIOLOGICAL TRANSPORT; CACO-2 CELLS; CARRIER PROTEINS; CETIRIZINE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG INTERACTIONS; HUMANS; INTESTINAL ABSORPTION; INTESTINAL MUCOSA; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; P-GLYCOPROTEIN; REPRODUCIBILITY OF RESULTS; STEREOISOMERISM; SUBSTRATE SPECIFICITY; TEMPERATURE;

EID: 77952763135     PISSN: 08990042     EISSN: 1520636X     Source Type: Journal    
DOI: 10.1002/chir.20815     Document Type: Article

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