Taste-masked quinine pamoate tablets for treatment of children with uncomplicated Plasmodium falciparum malaria

International Journal of Pharmaceutics

Volumn 392, Issue 1-2, 2010, Pages 29-34

  Kayitare, E ^a,b   Vervaet, C ^b   Mehuys, E ^b   Kayumba, P C ^a   Ntawukulilyayo, J D ^a   Karema, C ^a,c   Bortel, Van ^d   Remon, J P ^b  

^a UNIVERSITY OF RWANDA   (Rwanda)

^b GHENT UNIVERSITY   (Belgium)

^c TRAC plus/Malaria Unit   (Rwanda)

^d GHENT UNIVERSITY   (Belgium)

Author keywords

Bioavailability; Efficacy; Malaria; Paediatrics; Quinine; Tablets; Taste

Indexed keywords

MAGNESIUM STEARATE; MICROCRYSTALLINE CELLULOSE; QUININE; SILICON DIOXIDE; STARCH GLYCOLATE SODIUM;

ADULT; AREA UNDER THE CURVE; ARTICLE; CHILD; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG DESIGN; DRUG EFFICACY; DRUG HALF LIFE; DRUG SOLUBILITY; FEMALE; FEVER; HUMAN; MAJOR CLINICAL STUDY; MALARIA FALCIPARUM; MALE; MAXIMUM PLASMA CONCENTRATION; PARASITEMIA; PHYSICAL CHEMISTRY; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; SINGLE DRUG DOSE; TABLET DISINTEGRATION; TABLET FORMULATION; TABLET FRIABILITY; TASTE; TIME TO MAXIMUM PLASMA CONCENTRATION; TREATMENT DURATION;

ADMINISTRATION, ORAL; ADULT; ANTIMALARIALS; BIOLOGICAL AVAILABILITY; CHILD, PRESCHOOL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG COMPOUNDING; DRUG DELIVERY SYSTEMS; EXCIPIENTS; FEMALE; HUMANS; INFANT; MALARIA, FALCIPARUM; MALE; PLASMODIUM FALCIPARUM; PROSPECTIVE STUDIES; QUININE; SOLUBILITY; TABLETS; TASTE THRESHOLD; YOUNG ADULT;

EID: 77952741530     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2010.03.023     Document Type: Article

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