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Volumn 78, Issue 6, 2010, Pages 2397-2407

Use of the Cre-lox recombination system to investigate the lp54 gene requirement in the infectious cycle of Borrelia burgdorferi

Author keywords

[No Author keywords available]

Indexed keywords

CRE RECOMBINASE; DNA FRAGMENT; PROTEIN; PROTEIN LP54; UNCLASSIFIED DRUG;

EID: 77952715031     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.01059-09     Document Type: Article
Times cited : (25)

References (61)
  • 2
    • 0021671855 scopus 로고
    • Isolation and cultivation of Lyme disease spirochetes
    • Barbour, A. G. 1984. Isolation and cultivation of Lyme disease spirochetes. Yale J. Biol. Med. 57:521-525.
    • (1984) Yale J. Biol. Med. , vol.57 , pp. 521-525
    • Barbour, A.G.1
  • 3
    • 55849126646 scopus 로고    scopus 로고
    • Outer surface protein a protects Lyme disease spirochetes from acquired host immunity in the tick vector
    • Battisti, J. M., J. L. Bono, P. A. Rosa, M. E. Schrumpf, T. G. Schwan, and P. F. Policastro. 2008. Outer surface protein A protects Lyme disease spirochetes from acquired host immunity in the tick vector. Infect. Immun. 76:5228-5237.
    • (2008) Infect. Immun. , vol.76 , pp. 5228-5237
    • Battisti, J.M.1    Bono, J.L.2    Rosa, P.A.3    Schrumpf, M.E.4    Schwan, T.G.5    Policastro, P.F.6
  • 4
    • 21244445445 scopus 로고    scopus 로고
    • Mapping of essential replication functions of the linear plasmid lp17 of Borrelia burgdorferi by targeted deletion walking
    • Beaurepaire, C., and G. Chaconas. 2005. Mapping of essential replication functions of the linear plasmid lp17 of Borrelia burgdorferi by targeted deletion walking. Mol. Microbiol. 57:132-142.
    • (2005) Mol. Microbiol. , vol.57 , pp. 132-142
    • Beaurepaire, C.1    Chaconas, G.2
  • 5
    • 46249092176 scopus 로고    scopus 로고
    • Assessment of decorin-binding protein a to the infectivity of Borrelia burgdorferi in the murine models of needle and tick infection
    • Blevins, J. S., K. E. Hagman, and M. V. Norgard. 2008. Assessment of decorin-binding protein A to the infectivity of Borrelia burgdorferi in the murine models of needle and tick infection. BMC Microbiol. 8:82.
    • (2008) BMC Microbiol. , vol.8 , pp. 82
    • Blevins, J.S.1    Hagman, K.E.2    Norgard, M.V.3
  • 7
    • 0031967697 scopus 로고    scopus 로고
    • Oligopeptide permease in Borrelia burgdorferi: Putative peptide-binding components encoded by both chromosomal and plasmid loci
    • Bono, J. L., K. Tilly, B. Stevenson, D. Hogan, and P. Rosa. 1998. Oligopeptide permease in Borrelia burgdorferi: putative peptide-binding components encoded by both chromosomal and plasmid loci. Microbiology 144:1033-1044.
    • (1998) Microbiology , vol.144 , pp. 1033-1044
    • Bono, J.L.1    Tilly, K.2    Stevenson, B.3    Hogan, D.4    Rosa, P.5
  • 8
    • 0038104769 scopus 로고    scopus 로고
    • Global analysis of Borrelia burgdorferi genes regulated by mammalian host-specific signals
    • Brooks, C. S., P. S. Hefty, S. E. Jolliff, and D. R. Akins. 2003. Global analysis of Borrelia burgdorferi genes regulated by mammalian host-specific signals. Infect. Immun. 71:3371-3383.
    • (2003) Infect. Immun. , vol.71 , pp. 3371-3383
    • Brooks, C.S.1    Hefty, P.S.2    Jolliff, S.E.3    Akins, D.R.4
  • 9
    • 0038148642 scopus 로고    scopus 로고
    • An enhanced GFP reporter system to monitor gene expression in Borrelia burgdorferi
    • Carroll, J., P. Stewart, P. Rosa, and C. Garon. 2003. An enhanced GFP reporter system to monitor gene expression in Borrelia burgdorferi. Microbiology 149:1819-1828.
    • (2003) Microbiology , vol.149 , pp. 1819-1828
    • Carroll, J.1    Stewart, P.2    Rosa, P.3    Garon, C.4
  • 10
    • 0034441169 scopus 로고    scopus 로고
    • Identification of 11 pH-regulated genes in Borrelia burgdorferi localizing to linear plasmids
    • Carroll, J. A., R. M. Cordova, and C. F. Garon. 2000. Identification of 11 pH-regulated genes in Borrelia burgdorferi localizing to linear plasmids. Infect. Immun. 68:6677-6684.
    • (2000) Infect. Immun. , vol.68 , pp. 6677-6684
    • Carroll, J.A.1    Cordova, R.M.2    Garon, C.F.3
  • 12
    • 0035875922 scopus 로고    scopus 로고
    • Telomere resolution in the Lyme disease spirochete
    • DOI 10.1093/emboj/20.12.3229
    • Chaconas, G., P. E. Stewart, K. Tilly, J. L. Bono, and P. Rosa. 2001. Telomere resolution in the Lyme disease spirochete. EMBO J. 20:3229-3237. (Pubitemid 32612010)
    • (2001) EMBO Journal , vol.20 , Issue.12 , pp. 3229-3237
    • Chaconas, G.1    Stewart, P.E.2    Tilly, K.3    Bono, J.L.4    Rosa, P.5
  • 13
    • 57349152190 scopus 로고    scopus 로고
    • In vitro CpG methylation increases the transformation efficiency of Borrelia burgdorferi strains harboring the endogenous linear plasmid lp56
    • Chen, Q., J. R. Fischer, V. M. Benoit, N. P. Dufour, P. Youderian, and J. M. Leong. 2008. In vitro CpG methylation increases the transformation efficiency of Borrelia burgdorferi strains harboring the endogenous linear plasmid lp56. J. Bacteriol. 190:7885-7891.
    • (2008) J. Bacteriol. , vol.190 , pp. 7885-7891
    • Chen, Q.1    Fischer, J.R.2    Benoit, V.M.3    Dufour, N.P.4    Youderian, P.5    Leong, J.M.6
  • 16
    • 0029082449 scopus 로고
    • A 55-kilodalton antigen encoded by a gene on a Borrelia burgdorferi 49-kilobase plasmid is recognized by antibodies in sera from patients with Lyme disease
    • Feng, S., S. Das, T. Lam, R. A. Flavell, and E. Fikrig. 1995. A 55-kilodalton antigen encoded by a gene on a Borrelia burgdorferi 49-kilobase plasmid is recognized by antibodies in sera from patients with Lyme disease. Infect. Immun. 63:3459-3466.
    • (1995) Infect. Immun. , vol.63 , pp. 3459-3466
    • Feng, S.1    Das, S.2    Lam, T.3    Flavell, R.A.4    Fikrig, E.5
  • 19
    • 4644249919 scopus 로고    scopus 로고
    • Experimental assessment of the roles of linear plasmids lp25 and lp28-1 of Borrelia burgdorferi throughout the infectious cycle
    • Grimm, D., C. H. Eggers, M. J. Caimano, K. Tilly, P. E. Stewart, A. F. Elias, J. D. Radolf, and P. A. Rosa. 2004. Experimental assessment of the roles of linear plasmids lp25 and lp28-1 of Borrelia burgdorferi throughout the infectious cycle. Infect. Immun. 72:5938-5946.
    • (2004) Infect. Immun. , vol.72 , pp. 5938-5946
    • Grimm, D.1    Eggers, C.H.2    Caimano, M.J.3    Tilly, K.4    Stewart, P.E.5    Elias, A.F.6    Radolf, J.D.7    Rosa, P.A.8
  • 20
    • 0037767321 scopus 로고    scopus 로고
    • Plasmid stability during in vitro propagation of Borrelia burgdorferi assessed at a clonal level
    • Grimm, D., A. F. Elias, K. Tilly, and P. A. Rosa. 2003. Plasmid stability during in vitro propagation of Borrelia burgdorferi assessed at a clonal level. Infect. Immun. 71:3138-3145.
    • (2003) Infect. Immun. , vol.71 , pp. 3138-3145
    • Grimm, D.1    Elias, A.F.2    Tilly, K.3    Rosa, P.A.4
  • 22
    • 0005673882 scopus 로고
    • Interaction of the bacteriophage P1 recombinase Cre with the recombining site loxP
    • Hoess, R. H., and K. Abremski. 1984. Interaction of the bacteriophage P1 recombinase Cre with the recombining site loxP. Proc. Natl. Acad. Sci. U. S. A. 81:1026-1029.
    • (1984) Proc. Natl. Acad. Sci. U. S. A. , vol.81 , pp. 1026-1029
    • Hoess, R.H.1    Abremski, K.2
  • 23
    • 1842394365 scopus 로고
    • P1 site-specific recombination: Nucleotide sequence of the recombining sites
    • Hoess, R. H., M. Ziese, and N. Sternberg. 1982. P1 site-specific recombination: nucleotide sequence of the recombining sites. Proc. Natl. Acad. Sci. U. S. A. 79:3398-3402.
    • (1982) Proc. Natl. Acad. Sci. U. S. A. , vol.79 , pp. 3398-3402
    • Hoess, R.H.1    Ziese, M.2    Sternberg, N.3
  • 24
    • 0038310896 scopus 로고    scopus 로고
    • Linear and circular plasmid content in Borrelia burgdorferi clinical isolates
    • Iyer, R., O. Kalu, J. Purser, S. Norris, B. Stevenson, and I. Schwartz. 2003. Linear and circular plasmid content in Borrelia burgdorferi clinical isolates. Infect. Immun. 71:3699-3706.
    • (2003) Infect. Immun. , vol.71 , pp. 3699-3706
    • Iyer, R.1    Kalu, O.2    Purser, J.3    Norris, S.4    Stevenson, B.5    Schwartz, I.6
  • 27
    • 9244239222 scopus 로고    scopus 로고
    • BBE02 disruption mutants of Borrelia burgdorferi B31 have a highly transformable, infectious phenotype
    • Kawabata, H., S. J. Norris, and H. Watanabe. 2004. BBE02 disruption mutants of Borrelia burgdorferi B31 have a highly transformable, infectious phenotype. Infect. Immun. 72:7147-7154.
    • (2004) Infect. Immun. , vol.72 , pp. 7147-7154
    • Kawabata, H.1    Norris, S.J.2    Watanabe, H.3
  • 28
    • 67650070597 scopus 로고    scopus 로고
    • CspA-mediated binding of human factor H inhibits complement deposition and confers serum resistance in Borrelia burgdorferi
    • Kenedy, M. R., S. R. Vuppala, C. Siegel, P. Kraiczy, and D. R. Akins. 2009. CspA-mediated binding of human factor H inhibits complement deposition and confers serum resistance in Borrelia burgdorferi. Infect. Immun. 77:2773-2782.
    • (2009) Infect. Immun. , vol.77 , pp. 2773-2782
    • Kenedy, M.R.1    Vuppala, S.R.2    Siegel, C.3    Kraiczy, P.4    Akins, D.R.5
  • 29
    • 1642535449 scopus 로고    scopus 로고
    • Complement resistance of Borrelia burgdorferi correlates with the expression of BbCRASP-1, a novel linear plasmid-encoded surface protein that interacts with human factor H and FHL-1 and is unrelated to Erp proteins
    • Kraiczy, P., J. Hellwage, C. Skerka, H. Becker, M. Kirschfink, M. M. Simon, V. Brade, P. F. Zipfel, and R. Wallich. 2004. Complement resistance of Borrelia burgdorferi correlates with the expression of BbCRASP-1, a novel linear plasmid-encoded surface protein that interacts with human factor H and FHL-1 and is unrelated to Erp proteins. J. Biol. Chem. 279:2421-2429.
    • (2004) J. Biol. Chem. , vol.279 , pp. 2421-2429
    • Kraiczy, P.1    Hellwage, J.2    Skerka, C.3    Becker, H.4    Kirschfink, M.5    Simon, M.M.6    Brade, V.7    Zipfel, P.F.8    Wallich, R.9
  • 30
    • 0042766235 scopus 로고    scopus 로고
    • The absence of linear plasmid 25 or 28-1 of Borrelia burgdorferi dramatically alters the kinetics of experimental infection via distinct mechanisms
    • Labandeira-Rey, M., J. Seshu, and J. T. Skare. 2003. The absence of linear plasmid 25 or 28-1 of Borrelia burgdorferi dramatically alters the kinetics of experimental infection via distinct mechanisms. Infect. Immun. 71:4608-4613.
    • (2003) Infect. Immun. , vol.71 , pp. 4608-4613
    • Labandeira-Rey, M.1    Seshu, J.2    Skare, J.T.3
  • 31
    • 0035168567 scopus 로고    scopus 로고
    • Decreased infectivity in Borrelia burgdorferi strain B31 is associated with loss of linear plasmid 25 or 28-1
    • Labandeira-Rey, M., and J. T. Skare. 2001. Decreased infectivity in Borrelia burgdorferi strain B31 is associated with loss of linear plasmid 25 or 28-1. Infect. Immun. 69:446-455.
    • (2001) Infect. Immun. , vol.69 , pp. 446-455
    • Labandeira-Rey, M.1    Skare, J.T.2
  • 32
    • 0036716365 scopus 로고    scopus 로고
    • Decreased electroporation efficiency in Borrelia burgdorferi containing linear plasmids lp25 and lp56 impact on transformation of infectious B. burgdorferi
    • Lawrenz, M. B., H. Kawabata, J. E. Purser, and S. J. Norris. 2002. Decreased electroporation efficiency in Borrelia burgdorferi containing linear plasmids lp25 and lp56: impact on transformation of infectious B. burgdorferi. Infect. Immun. 70:4798-4804.
    • (2002) Infect. Immun. , vol.70 , pp. 4798-4804
    • Lawrenz, M.B.1    Kawabata, H.2    Purser, J.E.3    Norris, S.J.4
  • 35
    • 0034003709 scopus 로고    scopus 로고
    • Distribution of twelve linear extrachromosomal DNAs in natural isolates of Lyme disease spirochetes
    • DOI 10.1128/JB.182.9.2476-2480.2000
    • Palmer, N., C. Fraser, and S. Casjens. 2000. Distribution of twelve linear extrachromosomal DNAs in natural isolates of Lyme disease spirochetes. J. Bacteriol. 182:2476-2480. (Pubitemid 30212905)
    • (2000) Journal of Bacteriology , vol.182 , Issue.9 , pp. 2476-2480
    • Palmer, N.1    Fraser, C.2    Casjens, S.3
  • 36
    • 33744990631 scopus 로고    scopus 로고
    • The BBA01 protein a member of paralog family 48 from Borrelia burgdorferi, is potentially interchangeable with the channel-forming protein P13
    • Pinne, M., K. Denker, E. Nilsson, R. Benz, and S. Bergstrom. 2006. The BBA01 protein, a member of paralog family 48 from Borrelia burgdorferi, is potentially interchangeable with the channel-forming protein P13. J. Bacteriol. 188:4207-4217.
    • (2006) J. Bacteriol. , vol.188 , pp. 4207-4217
    • Pinne, M.1    Denker, K.2    Nilsson, E.3    Benz, R.4    Bergstrom, S.5
  • 37
    • 1642268055 scopus 로고    scopus 로고
    • Molecular analysis of the channel-forming protein P13 and its paralogue family 48 from different Lyme disease Borrelia species
    • Pinne, M., Y. Ostberg, P. Comstedt, and S. Bergström. 2004. Molecular analysis of the channel-forming protein P13 and its paralogue family 48 from different Lyme disease Borrelia species. Microbiology 150:549-559.
    • (2004) Microbiology , vol.150 , pp. 549-559
    • Pinne, M.1    Ostberg, Y.2    Comstedt, P.3    Bergström, S.4
  • 38
    • 0038687785 scopus 로고    scopus 로고
    • A plasmid-encoded nicotinamidase (PncA) is essential for infectivity of Borrelia burgdorferi in a mammalian host
    • Purser, J. E., M. B. Lawrenz, M. J. Caimano, J. D. Radolf, and S. J. Norris. 2003. A plasmid-encoded nicotinamidase (PncA) is essential for infectivity of Borrelia burgdorferi in a mammalian host. Mol. Microbiol. 48:753-764.
    • (2003) Mol. Microbiol. , vol.48 , pp. 753-764
    • Purser, J.E.1    Lawrenz, M.B.2    Caimano, M.J.3    Radolf, J.D.4    Norris, S.J.5
  • 39
    • 0034610332 scopus 로고    scopus 로고
    • Correlation between plasmid content and infectivity in Borrelia burgdorferi
    • Purser, J. E., and S. J. Norris. 2000. Correlation between plasmid content and infectivity in Borrelia burgdorferi. Proc. Natl. Acad. Sci. U. S. A. 97: 13865-13870.
    • (2000) Proc. Natl. Acad. Sci. U. S. A. , vol.97 , pp. 13865-13870
    • Purser, J.E.1    Norris, S.J.2
  • 40
    • 4644259956 scopus 로고    scopus 로고
    • Genetic exchange and plasmid transfers in Borrelia burgdorferi sensu stricto revealed by three-way genome comparisons and multilocus sequence typing
    • Qiu, W.-G., S. E. Schutzer, J. F. Bruno, O. Attie, Y. Xu, J. J. Dunn, C. Fraser, S. R. Casjens, and B. Luft. 2004. Genetic exchange and plasmid transfers in Borrelia burgdorferi sensu stricto revealed by three-way genome comparisons and multilocus sequence typing. Proc. Natl. Acad. Sci. U. S. A. 101:14150-14155.
    • (2004) Proc. Natl. Acad. Sci. U. S. A. , vol.101 , pp. 14150-14155
    • Qiu, W.-G.1    Schutzer, S.E.2    Bruno, J.F.3    Attie, O.4    Xu, Y.5    Dunn, J.J.6    Fraser, C.7    Casjens, S.R.8    Luft, B.9
  • 41
    • 0037022354 scopus 로고    scopus 로고
    • DNA microarray analysis of differential gene expression in Borrelia burgdorferi, the Lyme disease spirochete
    • Revel, A. T., A. M. Talaat, and M. V. Norgard. 2002. DNA microarray analysis of differential gene expression in Borrelia burgdorferi, the Lyme disease spirochete. Proc. Natl. Acad. Sci. U. S. A. 99:1562-1567.
    • (2002) Proc. Natl. Acad. Sci. U. S. A. , vol.99 , pp. 1562-1567
    • Revel, A.T.1    Talaat, A.M.2    Norgard, M.V.3
  • 42
    • 0029792859 scopus 로고    scopus 로고
    • Directed insertion of a selectable marker into a circular plasmid of Borrelia burgdorferi
    • Rosa, P., D. S. Samuels, D. Hogan, B. Stevenson, S. Casjens, and K. Tilly. 1996. Directed insertion of a selectable marker into a circular plasmid of Borrelia burgdorferi. J. Bacteriol. 178:5946-5953.
    • (1996) J. Bacteriol. , vol.178 , pp. 5946-5953
    • Rosa, P.1    Samuels, D.S.2    Hogan, D.3    Stevenson, B.4    Casjens, S.5    Tilly, K.6
  • 43
    • 13444293534 scopus 로고    scopus 로고
    • The burgeoning molecular genetics of the Lyme disease spirochaete
    • Rosa, P. A., K. Tilly, and P. E. Stewart. 2005. The burgeoning molecular genetics of the Lyme disease spirochaete. Nat. Rev. Microbiol. 3:129-143.
    • (2005) Nat. Rev. Microbiol. , vol.3 , pp. 129-143
    • Rosa, P.A.1    Tilly, K.2    Stewart, P.E.3
  • 44
    • 0026761405 scopus 로고
    • Antibody-resistant mutants of Borrelia burgdorferi: In vitro selection and characterization
    • Sǎdziene, A., P. A. Rosa, P. A. Thompson, D. M. Hogan, and A. G. Barbour. 1992. Antibody-resistant mutants of Borrelia burgdorferi: in vitro selection and characterization. J. Exp. Med. 176:799-809.
    • (1992) J. Exp. Med. , vol.176 , pp. 799-809
    • Sǎdziene, A.1    Rosa, P.A.2    Thompson, P.A.3    Hogan, D.M.4    Barbour, A.G.5
  • 45
    • 0027509237 scopus 로고
    • In vitro inhibition of Borrelia burgdorferi growth by antibodies
    • Sadziene, A., P. A. Thompson, and A. G. Barbour. 1993. In vitro inhibition of Borrelia burgdorferi growth by antibodies. J. Infect. Dis. 167:165-172.
    • (1993) J. Infect. Dis. , vol.167 , pp. 165-172
    • Sadziene, A.1    Thompson, P.A.2    Barbour, A.G.3
  • 46
    • 0027158861 scopus 로고
    • The cryptic ospC gene of Borrelia burgdorferi B31 is located on a circular plasmid
    • Sadziene, A., B. Wilske, M. S. Ferdows, and A. G. Barbour. 1993. The cryptic ospC gene of Borrelia burgdorferi B31 is located on a circular plasmid. Infect. Immun. 61:2192-2195.
    • (1993) Infect. Immun. , vol.61 , pp. 2192-2195
    • Sadziene, A.1    Wilske, B.2    Ferdows, M.S.3    Barbour, A.G.4
  • 47
    • 0029200874 scopus 로고
    • Electrotransformation of the spirochete Borrelia burgdorferi
    • Samuels, D. S. 1995. Electrotransformation of the spirochete Borrelia burgdorferi. Methods Mol. Biol. 47:253-259.
    • (1995) Methods Mol. Biol. , vol.47 , pp. 253-259
    • Samuels, D.S.1
  • 48
    • 0023753146 scopus 로고
    • Changes in infectivity and plasmid profile of the Lyme disease spirochete, Borrelia burgdorferi, as a result of in vitro cultivation
    • Schwan, T. G., W. Burgdorfer, and C. F. Garon. 1988. Changes in infectivity and plasmid profile of the Lyme disease spirochete, Borrelia burgdorferi, as a result of in vitro cultivation. Infect. Immun. 56:1831-1836.
    • (1988) Infect. Immun. , vol.56 , pp. 1831-1836
    • Schwan, T.G.1    Burgdorfer, W.2    Garon, C.F.3
  • 49
    • 40749130867 scopus 로고    scopus 로고
    • Both decorin-binding proteins a and B are critical for overall virulence of Borrelia burgdorferi
    • Shi, Y., Q. Xu, K. McShan, and F. T. Liang. 2008. Both decorin-binding proteins A and B are critical for overall virulence of Borrelia burgdorferi. Infect. Immun. 76:1239-1246.
    • (2008) Infect. Immun. , vol.76 , pp. 1239-1246
    • Shi, Y.1    Xu, Q.2    McShan, K.3    Liang, F.T.4
  • 50
    • 33750475236 scopus 로고    scopus 로고
    • The dbpBA locus of Borrelia burgdorferi is not essential for infection of mice
    • Shi, Y., Q. Xu, S. V. Seemanapalli, K. McShan, and F. T. Liang. 2006. The dbpBA locus of Borrelia burgdorferi is not essential for infection of mice. Infect. Immun. 74:6509-6512.
    • (2006) Infect. Immun. , vol.74 , pp. 6509-6512
    • Shi, Y.1    Xu, Q.2    Seemanapalli, S.V.3    McShan, K.4    Liang, F.T.5
  • 51
    • 0022512704 scopus 로고
    • Bacteriophage P1 cre gene and its regulatory region. Evidence for multiple promoters and for regulation by DNA methylation
    • Sternberg, N., B. Sauer, R. Hoess, and K. Abremski. 1986. Bacteriophage P1 cre gene and its regulatory region. Evidence for multiple promoters and for regulation by DNA methylation. J. Mol. Biol. 187:197-212.
    • (1986) J. Mol. Biol. , vol.187 , pp. 197-212
    • Sternberg, N.1    Sauer, B.2    Hoess, R.3    Abremski, K.4
  • 52
    • 0038643161 scopus 로고    scopus 로고
    • Conservation of plasmid maintenance functions between linear and circular plasmids in Borrelia burgdorferi
    • Stewart, P. E., G. Chaconas, and P. Rosa. 2003. Conservation of plasmid maintenance functions between linear and circular plasmids in Borrelia burgdorferi. J. Bacteriol. 185:3202-3209.
    • (2003) J. Bacteriol. , vol.185 , pp. 3202-3209
    • Stewart, P.E.1    Chaconas, G.2    Rosa, P.3
  • 53
    • 0035131631 scopus 로고    scopus 로고
    • Isolation of a circular plasmid region sufficient for autonomous replication and transformation of infectious Borrelia burgdorferi
    • Stewart, P. E., R. Thalken, J. L. Bono, and P. Rosa. 2001. Isolation of a circular plasmid region sufficient for autonomous replication and transformation of infectious Borrelia burgdorferi. Mol. Microbiol. 39:714-721.
    • (2001) Mol. Microbiol. , vol.39 , pp. 714-721
    • Stewart, P.E.1    Thalken, R.2    Bono, J.L.3    Rosa, P.4
  • 54
    • 33749019718 scopus 로고    scopus 로고
    • Comparative genome hybridization reveals substantial variation among clinical isolates of Borrelia burgdorferi sensu stricto with different pathogenic properties
    • Terekhova, D., R. Iyer, G. P. Wormser, and I. Schwartz. 2006. Comparative genome hybridization reveals substantial variation among clinical isolates of Borrelia burgdorferi sensu stricto with different pathogenic properties. J. Bacteriol. 188:6124-6134.
    • (2006) J. Bacteriol. , vol.188 , pp. 6124-6134
    • Terekhova, D.1    Iyer, R.2    Wormser, G.P.3    Schwartz, I.4
  • 56
    • 4544350205 scopus 로고    scopus 로고
    • Combined effects of blood and temperature shift on Borrelia burgdorferi gene expression as determined by whole genome DNA array
    • Tokarz, R., J. M. Anderton, L. I. Katona, and J. L. Benach. 2004. Combined effects of blood and temperature shift on Borrelia burgdorferi gene expression as determined by whole genome DNA array. Infect. Immun. 72:5419-5432.
    • (2004) Infect. Immun. , vol.72 , pp. 5419-5432
    • Tokarz, R.1    Anderton, J.M.2    Katona, L.I.3    Benach, J.L.4
  • 57
    • 57349121039 scopus 로고    scopus 로고
    • Borrelia burgdorferi lacking DbpBA exhibits an early survival defect during experimental infection
    • Weening, E. H., N. Parveen, J. P. Trzeciakowski, J. M. Leong, M. Hook, and J. T. Skare. 2008. Borrelia burgdorferi lacking DbpBA exhibits an early survival defect during experimental infection. Infect. Immun. 76:5694-5705.
    • (2008) Infect. Immun. , vol.76 , pp. 5694-5705
    • Weening, E.H.1    Parveen, N.2    Trzeciakowski, J.P.3    Leong, J.M.4    Hook, M.5    Skare, J.T.6
  • 58
    • 0029150939 scopus 로고
    • Analysis and comparison of plasmid profiles of Borrelia burgdorferi sensu lato strains
    • Xu, Y., and R. C. Johnson. 1995. Analysis and comparison of plasmid profiles of Borrelia burgdorferi sensu lato strains. J. Clin. Microbiol. 33:2679-2685.
    • (1995) J. Clin. Microbiol. , vol.33 , pp. 2679-2685
    • Xu, Y.1    Johnson, R.C.2
  • 59
    • 0029779949 scopus 로고    scopus 로고
    • Correlation of plasmids with infectivity of Borrelia burgdorferi sensu stricto type strain B31
    • Xu, Y., C. Kodner, L. Coleman, and R. C. Johnson. 1996. Correlation of plasmids with infectivity of Borrelia burgdorferi sensu stricto type strain B31. Infect. Immun. 64:3870-3876.
    • (1996) Infect. Immun. , vol.64 , pp. 3870-3876
    • Xu, Y.1    Kodner, C.2    Coleman, L.3    Johnson, R.C.4
  • 60
    • 1542283705 scopus 로고    scopus 로고
    • Essential role for OspA/B in the life cycle of the Lyme disease spirochete
    • Yang, X. F., U. Pal, S. M. Alani, E. Fikrig, and M. V. Norgard. 2004. Essential role for OspA/B in the life cycle of the Lyme disease spirochete. J. Exp. Med. 199:641-648.
    • (2004) J. Exp. Med. , vol.199 , pp. 641-648
    • Yang, X.F.1    Pal, U.2    Alani, S.M.3    Fikrig, E.4    Norgard, M.V.5
  • 61
    • 3843146246 scopus 로고    scopus 로고
    • An efficient one-step site-directed and site-saturation mutagenesis protocol
    • Zheng, L., U. Baumann, and J. L. Reymond. 2004. An efficient one-step site-directed and site-saturation mutagenesis protocol. Nucleic Acids Res. 32:e115.
    • (2004) Nucleic Acids Res. , vol.32
    • Zheng, L.1    Baumann, U.2    Reymond, J.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.