Prolyl oligopeptidase of Trypanosoma brucei hydrolyzes native collagen, peptide hormones and is active in the plasma of infected mice

Microbes and Infection

Volumn 12, Issue 6, 2010, Pages 457-466

  Bastos, Izabela M D ^a   Motta, Flávia Nader ^a   Charneau, Sébastien ^a   Santana, Jaime M ^a   Dubost, Lionel ^b   Augustyns, Koen ^c   Grellier, Philippe ^b  

^a UNIVERSITY OF BRASILIA   (Brazil)

^b MUSÉUM NATIONAL D'HISTOIRE NATURELLE   (France)

^c UNIVERSITY OF ANTWERP   (Belgium)

Author keywords

Collagen hydrolysis; Peptide hormone; Prolyl oligopeptidase; Prolyl oligopeptidase inhibitors; Sleeping sickness; Trypanosoma brucei

Indexed keywords

COLLAGEN; PEPTIDE HORMONE; PROLYL ENDOPEPTIDASE; PROTEINASE INHIBITOR; SERINE PROTEINASE;

AFRICAN TRYPANOSOMIASIS; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME STRUCTURE; HYDROLYSIS; MESENTERY; MICROBIAL GROWTH; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PLASMA; PRIORITY JOURNAL; RAT; TRYPANOSOMA BRUCEI; ANIMAL; BLOOD; ENZYMOLOGY; GENETICS; HOST PARASITE INTERACTION; HUMAN; METABOLISM; PHYSIOLOGY; POLYACRYLAMIDE GEL ELECTROPHORESIS; TRYPANOSOMA BRUCEI BRUCEI;

ANIMALS; COLLAGEN; CONSERVED SEQUENCE; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HOST-PARASITE INTERACTIONS; HUMANS; MICE; PEPTIDE HORMONES; PROTEASE INHIBITORS; RATS; SERINE ENDOPEPTIDASES; TRYPANOSOMA BRUCEI BRUCEI; TRYPANOSOMIASIS, AFRICAN;

MUS; RATTUS; TRYPANOSOMA BRUCEI; TRYPANOSOMA CRUZI;

EID: 77952675691     PISSN: 12864579     EISSN: 1769714X     Source Type: Journal    
DOI: 10.1016/j.micinf.2010.02.007     Document Type: Article

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