Involvement of cytosolic prolyl endopeptidase in degradation of p40-phox splice variant protein in myeloid cells

Journal of Leukocyte Biology

Volumn 69, Issue 6, 2001, Pages 963-968

  Hasebe, T ^a   Hua, J ^a   Someya, A ^a   Morain, P ^a   Checler, F ^a   Nagaoka, I ^a  

^a JUNTENDO UNIVERSITY   (Japan)

Author keywords

Alternative splicing; HL 60; NADPH oxidase; Proteolysis

Indexed keywords

MESSENGER RNA; PROLYL ENDOPEPTIDASE INHIBITOR; PROTEINASE INHIBITOR; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; S 17092 1; UNCLASSIFIED DRUG;

ALTERNATIVE RNA SPLICING; ARTICLE; BONE MARROW CELL; CELL FRACTIONATION; CELL STRAIN HL 60; CONTROLLED STUDY; CYTOSOL; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; LEUKEMIA CELL; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN DEGRADATION;

ALTERNATIVE SPLICING; CYTOPLASMIC GRANULES; CYTOSOL; HL-60 CELLS; HUMANS; MYELOID CELLS; NADPH OXIDASE; NEOPLASM PROTEINS; PHOSPHOPROTEINS; PROTEASE INHIBITORS; RNA, MESSENGER; SERINE ENDOPEPTIDASES; SUBCELLULAR FRACTIONS; SUBSTRATE SPECIFICITY;

EID: 0034976880     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (42)

1. NADPH oxidase: An update
2. Purification of the 260 kDa cytosolic complex involved in the superoxide production of guinea pig neutrophils
3. p40-phox, a third cytosolic component of the activation complex of the NADPH oxidase to contain src homology 3 domains
4. A novel cytosolic component, p40-phox, of respiratory burst oxidase associates with p67-phox is absent in patients with chronic granulomatous disease who lack p67-phox
5. Translocation of guinea pig p40-phox during activation of NADPH oxidase
6. Involvement of p40-phox in activation of phagocyte NADPH oxidase through association of its carboxy-terminal, but not its amino-terminal, with p67-phox
7. The 40-kDa component of the phagocyte NADPH oxidase (p40phox) is phosphorylated during activation in differentiated HL60 cells
8. p40-phox is phosphorylated on threonine 154 and serine 315 during activation of the phagocyte NADPH oxidase
9. Phosphorylation of p40-phox during activation of neutrophil NADPH oxidase
10. 558
11. p40-phox down-regulates NADPH oxidase activity through interactions with its SH3 domain
12. Complementation of NADPH oxidase in p67-phox-defient CGD patients: p67-phox/ p40-phox interaction
13. Genomic structure, chromosomal location, start of transcription, and tissue expression of the human p40-phox, a new component of the nicotinamide adenine dinucleotide phosphate-oxidase complex
14. Identification of a splice variant mRNA of p40-phox, an NADPH oxidase component of phagocytes
15. New prolyl endopeptidase inhibitors: In vitro and in vivo activities of azabicyclo[2.2.2]octane, azabicyclo[2.2.1]heptane, and perhydroindole derivatives
16. S17092-1, a highly potent, specific and cell permeant inhibitor of human proline endopeptidase
17. Continuous growth and differentiation of human myeloid leukaemic cells in suspension culture
18. Possible involvement of aminopeptidase, an ecto-enzyme, in the inactivation of bradykinin by intact neutrophils
19. Isolation of cDNA encoding guinea pig neutrophil cationic antibacterial polypeptide of 11 kDa (CAP11) and evaluation of CAP11 mRNA expression during neutrophil maturation
20. Studies on human polymorphonuclear leukocyte enzymes. I. Assay of acid hydrolases and other enzymes
21. Lactate dehydrogenase
22. Resolution of granules from rabbit heterophil leukocytes into distinct populations by zonal sedimentation
23. Changes in prolyl endopeptidase during maturation of rat brain and hydrolysis of substance P by the purified enzyme
24. Quantitation of total DNA per cell in an exponentially growing population using the diphenylamine reaction and flow cytometry
25. Cleavage of structural proteins during the assembly of the head of bacteriophage T4
26. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications
27. Transmembrane linkage between surface glycoproteins and components of the cytoplasm in neutrophil leukocytes
28. Comparison of the effect of calpain inhibitors on two extralysosomal proteinases: The multi-catalytic proteinase complex and m-calpain
29. Differential inhibition of calpain and proteasome activities by peptidyl aldehydes of di-leucine and tri-leucine
30. Proline-specific endopeptidase from Flavobacterium
31. Evaluation of the expression of NADPH oxidase components during maturation of HL-60 cells to neutrophil lineage
32. Defective c-myc and c-myb RNA turnover in acute myeloid leukemia cells
33. Single-step method of RNA isolation by acid guanidinium thiocyate-phenol-chloroform extraction
34. Peptide sequences that target cytosolic proteins for lysosomal proteolysis
35. A role for a 70-kilodalton heat shock protein in lysosomal degradation of intracellular proteins
36. A receptor for the selective uptake and degradation of proteins by lysosomes
37. PSORT: A program for detecting sorting signals in proteins and predicting their subcellular localization
38. Modes of regulation of ubiquitin-mediated protein degradation
39. Calpain: A protease in search of a function?
40. Amino acid sequences common to rapidly degraded proteins: The PEST hypothesis
41. PEST sequences and regulation by proteolysis
42. SOPM: A self-optimized method for protein secondary structure prediction