-
1
-
-
22344435817
-
The ras effector RASSF2 is a novel tumor-suppressor gene in human colorectal cancer
-
DOI 10.1053/j.gastro.2005.03.051, PII S0016508505005743
-
Akino, K., M. Toyota, H. Suzuki, H. Mita, Y. Sasaki, M. Ohe-Toyota, J. P. Issa, Y. Hinoda, K. Imai, and T. Tokino. 2005. The Ras effector RASSF2 is a novel tumor-suppressor gene in human colorectal cancer. Gastroenterology 129:156-169. (Pubitemid 41002052)
-
(2005)
Gastroenterology
, vol.129
, Issue.1
, pp. 156-169
-
-
Akino, K.1
Toyota, M.2
Suzuki, H.3
Mita, H.4
Sasaki, Y.5
Ohe-Toyota, M.6
Issa, J.-P.J.7
Hinoda, Y.8
Imai, K.9
Tokino, T.10
-
2
-
-
0035022291
-
Deregulated expression of prostate apoptosis response gene-4 in less differentiated lymphocytes and inverse expressional patterns of par-4 and bcl-2 in acute lymphocytic leukemia
-
Boehrer, S., K. U. Chow, E. Puccetti, M. Ruthardt, S. Godzisard, A. Krapohl, B. Schneider, D. Hoelzer, P. S. Mitrou, V. M. Rangnekar, and E. Weidmann. 2001. Deregulated expression of prostate apoptosis response gene-4 in less differentiated lymphocytes and inverse expressional patterns of par-4 and bcl-2 in acute lymphocytic leukemia. Hematol. J. 2:103-107.
-
(2001)
Hematol. J.
, vol.2
, pp. 103-107
-
-
Boehrer, S.1
Chow, K.U.2
Puccetti, E.3
Ruthardt, M.4
Godzisard, S.5
Krapohl, A.6
Schneider, B.7
Hoelzer, D.8
Mitrou, P.S.9
Rangnekar, V.M.10
Weidmann, E.11
-
3
-
-
33644871502
-
Prostate-apoptosis-response-gene-4 increases sensitivity to TRAIL-induced apoptosis
-
Boehrer, S., D. Nowak, E. Puccetti, M. Ruthardt, N. Sattler, B. Trepohl, B. Schneider, D. Hoelzer, P. S. Mitrou, and K. U. Chow. 2006. Prostate-apoptosis-response-gene-4 increases sensitivity to TRAIL-induced apoptosis. Leuk. Res. 30:597-605.
-
(2006)
Leuk. Res.
, vol.30
, pp. 597-605
-
-
Boehrer, S.1
Nowak, D.2
Puccetti, E.3
Ruthardt, M.4
Sattler, N.5
Trepohl, B.6
Schneider, B.7
Hoelzer, D.8
Mitrou, P.S.9
Chow, K.U.10
-
4
-
-
33645976174
-
Ubiquitous activation of Ras and Jak/Stat pathways in human HCC
-
Calvisi, D. F., S. Ladu, A. Gorden, M. Farina, E. A. Conner, J. S. Lee, V. M. Factor, and S. S. Thorgeirsson. 2006. Ubiquitous activation of Ras and Jak/Stat pathways in human HCC. Gastroenterology 130:1117-1128.
-
(2006)
Gastroenterology
, vol.130
, pp. 1117-1128
-
-
Calvisi, D.F.1
Ladu, S.2
Gorden, A.3
Farina, M.4
Conner, E.A.5
Lee, J.S.6
Factor, V.M.7
Thorgeirsson, S.S.8
-
5
-
-
0035477544
-
Par-4 drives trafficking and activation of Fas and Fasl to induce prostate cancer cell apoptosis and tumor regression
-
Chakraborty, M., S. G. Qiu, K. M. Vasudevan, and V. M. Rangnekar. 2001. Par-4 drives trafficking and activation of Fas and Fasl to induce prostate cancer cell apoptosis and tumor regression. Cancer Res. 61:7255-7263.
-
(2001)
Cancer Res.
, vol.61
, pp. 7255-7263
-
-
Chakraborty, M.1
Qiu, S.G.2
Vasudevan, K.M.3
Rangnekar, V.M.4
-
6
-
-
0033521923
-
Decreased expression of the pro-apoptotic protein Par-4 in renal cell carcinoma
-
Cook, J., S. Krishnan, S. Ananth, S. F. Sells, Y. Shi, M. M. Walther, W. M. Linehan, V. P. Sukhatme, M. H. Weinstein, and V. M. Rangnekar. 1999. Decreased expression of the pro-apoptotic protein Par-4 in renal cell carcinoma. Oncogene 18:1205-1208.
-
(1999)
Oncogene
, vol.18
, pp. 1205-1208
-
-
Cook, J.1
Krishnan, S.2
Ananth, S.3
Sells, S.F.4
Shi, Y.5
Walther, M.M.6
Linehan, W.M.7
Sukhatme, V.P.8
Weinstein, M.H.9
Rangnekar, V.M.10
-
7
-
-
40749133034
-
Epigenetic regulation of the ras effector/tumour suppressor RASSF2 in breast and lung cancer
-
Cooper, W. N., R. E. Dickinson, A. Dallol, E. V. Grigorieva, T. V. Pavlova, L. B. Hesson, I. Bieche, M. Broggini, E. R. Maher, E. R. Zabarovsky, G. J. Clark, and F. Latif. 2008. Epigenetic regulation of the ras effector/tumour suppressor RASSF2 in breast and lung cancer. Oncogene 27:1805-1811.
-
(2008)
Oncogene
, vol.27
, pp. 1805-1811
-
-
Cooper, W.N.1
Dickinson, R.E.2
Dallol, A.3
Grigorieva, E.V.4
Pavlova, T.V.5
Hesson, L.B.6
Bieche, I.7
Broggini, M.8
Maher, E.R.9
Zabarovsky, E.R.10
Clark, G.J.11
Latif, F.12
-
8
-
-
69249217720
-
RASSF2 associates with and stabilizes the proapoptotic kinase MST2
-
Cooper, W. N., L. B. Hesson, D. Matallanas, A. Dallol, A. von Kriegsheim, R. Ward, W. Kolch, and F. Latif. 2009. RASSF2 associates with and stabilizes the proapoptotic kinase MST2. Oncogene 28:2988-2998.
-
(2009)
Oncogene
, vol.28
, pp. 2988-2998
-
-
Cooper, W.N.1
Hesson, L.B.2
Matallanas, D.3
Dallol, A.4
Von Kriegsheim, A.5
Ward, R.6
Kolch, W.7
Latif, F.8
-
9
-
-
17444437545
-
A real-time PCR assay for DNA-methylation using methylation-specific blockers
-
Cottrell, S. E., J. Distler, N. S. Goodman, S. H. Mooney, A. Kluth, A. Olek, I. Schwope, R. Tetzner, H. Ziebarth, and K. Berlin. 2004. A real-time PCR assay for DNA-methylation using methylation-specific blockers. Nucleic Acids Res. 32:e10.
-
(2004)
Nucleic Acids Res.
, vol.32
-
-
Cottrell, S.E.1
Distler, J.2
Goodman, N.S.3
Mooney, S.H.4
Kluth, A.5
Olek, A.6
Schwope, I.7
Tetzner, R.8
Ziebarth, H.9
Berlin, K.10
-
10
-
-
1642553461
-
The dark side of Ras: Regulation of apoptosis
-
Cox, A. D., and C. J. Der. 2003. The dark side of Ras: regulation of apoptosis. Oncogene 22:8999-9006.
-
(2003)
Oncogene
, vol.22
, pp. 8999-9006
-
-
Cox, A.D.1
Der, C.J.2
-
11
-
-
0030572696
-
The product of par-4, a gene induced during apoptosis, interacts selectively with the atypical isoforms of protein kinase C
-
Diaz-Meco, M. T., M. M. Municio, S. Frutos, P. Sanchez, J. Lozano, L. Sanz, and J. Moscat. 1996. The product of par-4, a gene induced during apoptosis, interacts selectively with the atypical isoforms of protein kinase C. Cell 86:777-786.
-
(1996)
Cell
, vol.86
, pp. 777-786
-
-
Diaz-Meco, M.T.1
Municio, M.M.2
Frutos, S.3
Sanchez, P.4
Lozano, J.5
Sanz, L.6
Moscat, J.7
-
13
-
-
0037264633
-
Targeting RAS signalling pathways in cancer therapy
-
Downward, J. 2003. Targeting RAS signalling pathways in cancer therapy. Nat. Rev. Cancer 3:11-22.
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 11-22
-
-
Downward, J.1
-
14
-
-
0035870280
-
Epigenetic patterns in the progression of esophageal adenocarcinoma
-
Eads, C. A., R. V. Lord, K. Wickramasinghe, T. I. Long, S. K. Kurumboor, L. Bernstein, J. H. Peters, S. R. DeMeester, T. R. DeMeester, K. A. Skinner, and P. W. Laird. 2001. Epigenetic patterns in the progression of esophageal adenocarcinoma. Cancer Res. 61:3410-3418.
-
(2001)
Cancer Res.
, vol.61
, pp. 3410-3418
-
-
Eads, C.A.1
Lord, R.V.2
Wickramasinghe, K.3
Long, T.I.4
Kurumboor, S.K.5
Bernstein, L.6
Peters, J.H.7
DeMeester, S.R.8
DeMeester, T.R.9
Skinner, K.A.10
Laird, P.W.11
-
15
-
-
0043133881
-
Identification of a unique core domain of par-4 sufficient for selective apoptosis induction in cancer cells
-
El-Guendy, N., Y. Zhao, S. Gurumurthy, R. Burikhanov, and V. M. Rangnekar. 2003. Identification of a unique core domain of par-4 sufficient for selective apoptosis induction in cancer cells. Mol. Cell. Biol. 23:5516-5525.
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 5516-5525
-
-
El-Guendy, N.1
Zhao, Y.2
Gurumurthy, S.3
Burikhanov, R.4
Rangnekar, V.M.5
-
16
-
-
28644450906
-
RASSF2, a potential tumour suppressor, is silenced by CpG island hypermethylation in gastric cancer
-
DOI 10.1038/sj.bjc.6602854
-
Endoh, M., G. Tamura, T. Honda, N. Homma, M. Terashima, S. Nishizuka, and T. Motoyama. 2005. RASSF2, a potential tumour suppressor, is silenced by CpG island hypermethylation in gastric cancer. Br. J. Cancer 93:1395-1399. (Pubitemid 41752867)
-
(2005)
British Journal of Cancer
, vol.93
, Issue.12
, pp. 1395-1399
-
-
Endoh, M.1
Tamura, G.2
Honda, T.3
Homma, N.4
Terashima, M.5
Nishizuka, S.6
Motoyama, T.7
-
17
-
-
9144262332
-
Identification of the E1A-regulated transcription factor p120 E4F as an interacting partner of the RASSF1A candidate tumor suppressor gene
-
Fenton, S. L., A. Dallol, A. Agathanggelou, L. Hesson, J. Ahmed-Choudhury, S. Baksh, C. Sardet, R. Dammann, J. D. Minna, J. Downward, E. R. Maher, and F. Latif. 2004. Identification of the E1A-regulated transcription factor p120 E4F as an interacting partner of the RASSF1A candidate tumor suppressor gene. Cancer Res. 64:102-107.
-
(2004)
Cancer Res.
, vol.64
, pp. 102-107
-
-
Fenton, S.L.1
Dallol, A.2
Agathanggelou, A.3
Hesson, L.4
Ahmed-Choudhury, J.5
Baksh, S.6
Sardet, C.7
Dammann, R.8
Minna, J.D.9
Downward, J.10
Maher, E.R.11
Latif, F.12
-
18
-
-
0035067298
-
Mammalian expression vectors for Ras family proteins: Generation and use of expression constructs to analyze Ras family function
-
Fiordalisi, J. J., R. L. Johnson II, A. S. Ulku, C. J. Der, and A. D. Cox. 2001. Mammalian expression vectors for Ras family proteins: generation and use of expression constructs to analyze Ras family function. Methods Enzymol. 332:3-36.
-
(2001)
Methods Enzymol.
, vol.332
, pp. 3-36
-
-
Fiordalisi, J.J.1
Johnson II, R.L.2
Ulku, A.S.3
Der, C.J.4
Cox, A.D.5
-
19
-
-
22144496103
-
Tumour-suppression activity of the proapoptotic regulator Par4
-
DOI 10.1038/sj.embor.7400421
-
Garcia-Cao, I., A. Duran, M. Collado, M. J. Carrascosa, J. Martin-Caballero, J. M. Flores, M. T. Diaz-Meco, J. Moscat, and M. Serrano. 2005. Tumour-suppression activity of the proapoptotic regulator Par4. EMBO Rep. 6:577-583. (Pubitemid 40973968)
-
(2005)
EMBO Reports
, vol.6
, Issue.6
, pp. 577-583
-
-
Garcia-Cao, I.1
Duran, A.2
Collado, M.3
Carrascosa, M.J.4
Martin-Caballero, J.5
Flores, J.M.6
Diaz-Meco, M.T.7
Moscat, J.8
Serrano, M.9
-
20
-
-
0242585506
-
Genetic inactivation of Par4 results in hyperactivation of NF-κB and impairment of JNK and p38
-
DOI 10.1038/sj.embor.embor769
-
Garcia-Cao, I., M. J. Lafuente, L. M. Criado, M. T. Diaz-Meco, M. Serrano, and J. Moscat. 2003. Genetic inactivation of Par4 results in hyperactivation of NF-κB and impairment of JNK and p38. EMBO Rep. 4:307-312. (Pubitemid 36511729)
-
(2003)
EMBO Reports
, vol.4
, Issue.3
, pp. 307-312
-
-
Garcia-Cao, I.1
Lafuente, M.J.2
Criado, L.M.3
Diaz-Meco, M.T.4
Serrano, M.5
Moscat, J.6
-
21
-
-
25844454851
-
Binding and phosphorylation of par-4 by akt is essential for cancer cell survival
-
Goswami, A., R. Burikhanov, A. de Thonel, N. Fujita, M. Goswami, Y. Zhao, J. E. Eriksson, T. Tsuruo, and V. M. Rangnekar. 2005. Binding and phosphorylation of par-4 by akt is essential for cancer cell survival. Mol. Cell 20:33-44.
-
(2005)
Mol. Cell
, vol.20
, pp. 33-44
-
-
Goswami, A.1
Burikhanov, R.2
De Thonel, A.3
Fujita, N.4
Goswami, M.5
Zhao, Y.6
Eriksson, J.E.7
Tsuruo, T.8
Rangnekar, V.M.9
-
22
-
-
34047250808
-
RASSF1A is part of a complex similar to the Drosophila Hippo/Salvador/Lats tumor-suppressor network
-
Guo, C., S. Tommasi, L. Liu, J. K. Yee, R. Dammann, and G. P. Pfeifer. 2007. RASSF1A is part of a complex similar to the Drosophila Hippo/Salvador/Lats tumor-suppressor network. Curr. Biol. 17:700-705.
-
(2007)
Curr. Biol.
, vol.17
, pp. 700-705
-
-
Guo, C.1
Tommasi, S.2
Liu, L.3
Yee, J.K.4
Dammann, R.5
Pfeifer, G.P.6
-
23
-
-
12844253808
-
Phosphorylation of Par-4 by protein kinase a is critical for apoptosis
-
Gurumurthy, S., A. Goswami, K. M. Vasudevan, and V. M. Rangnekar. 2005. Phosphorylation of Par-4 by protein kinase A is critical for apoptosis. Mol. Cell. Biol. 25:1146-1161.
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 1146-1161
-
-
Gurumurthy, S.1
Goswami, A.2
Vasudevan, K.M.3
Rangnekar, V.M.4
-
24
-
-
20544445183
-
CpG island promoter hypermethylation of a novel Raseffector gene RASSF2A is an early event in colon carcinogenesis and correlates inversely with K-ras mutations
-
Hesson, L. B., R. Wilson, D. Morton, C. Adams, M. Walker, E. R. Maher, and F. Latif. 2005. CpG island promoter hypermethylation of a novel Raseffector gene RASSF2A is an early event in colon carcinogenesis and correlates inversely with K-ras mutations. Oncogene 24:3987-3994.
-
(2005)
Oncogene
, vol.24
, pp. 3987-3994
-
-
Hesson, L.B.1
Wilson, R.2
Morton, D.3
Adams, C.4
Walker, M.5
Maher, E.R.6
Latif, F.7
-
25
-
-
43649098854
-
Epigenetic inactivation of RASSF2 in oral squamous cell carcinoma
-
Imai, T., M. Toyota, H. Suzuki, K. Akino, K. Ogi, Y. Sogabe, L. Kashima, R. Maruyama, M. Nojima, H. Mita, Y. Sasaki, F. Itoh, K. Imai, Y. Shinomura, H. Hiratsuka, and T. Tokino. 2008. Epigenetic inactivation of RASSF2 in oral squamous cell carcinoma. Cancer Sci. 99:958-966.
-
(2008)
Cancer Sci.
, vol.99
, pp. 958-966
-
-
Imai, T.1
Toyota, M.2
Suzuki, H.3
Akino, K.4
Ogi, K.5
Sogabe, Y.6
Kashima, L.7
Maruyama, R.8
Nojima, M.9
Mita, H.10
Sasaki, Y.11
Itoh, F.12
Imai, K.13
Shinomura, Y.14
Hiratsuka, H.15
Tokino, T.16
-
26
-
-
49949109707
-
Par-4 inhibits Akt and suppresses Ras-induced lung tumorigenesis
-
Joshi, J., P. J. Fernandez-Marcos, A. Galvez, R. Amanchy, J. F. Linares, A. Duran, P. Pathrose, M. Leitges, M. Canamero, M. Collado, C. Salas, M. Serrano, J. Moscat, and M. T. Diaz-Meco. 2008. Par-4 inhibits Akt and suppresses Ras-induced lung tumorigenesis. EMBO J. 27:2181-2193.
-
(2008)
EMBO J.
, vol.27
, pp. 2181-2193
-
-
Joshi, J.1
Fernandez-Marcos, P.J.2
Galvez, A.3
Amanchy, R.4
Linares, J.F.5
Duran, A.6
Pathrose, P.7
Leitges, M.8
Canamero, M.9
Collado, M.10
Salas, C.11
Serrano, M.12
Moscat, J.13
Diaz-Meco, M.T.14
-
27
-
-
34548277011
-
Epigenetic inactivation of the RAS-effector gene RASSF2 in lung cancers
-
Kaira, K., N. Sunaga, Y. Tomizawa, N. Yanagitani, T. Ishizuka, R. Saito, T. Nakajima, and M. Mori. 2007. Epigenetic inactivation of the RAS-effector gene RASSF2 in lung cancers. Int. J. Oncol. 31:169-173.
-
(2007)
Int. J. Oncol.
, vol.31
, pp. 169-173
-
-
Kaira, K.1
Sunaga, N.2
Tomizawa, Y.3
Yanagitani, N.4
Ishizuka, T.5
Saito, R.6
Nakajima, T.7
Mori, M.8
-
28
-
-
0037133034
-
Identification of a novel Ras-regulated proapoptotic pathway
-
Khokhlatchev, A., S. Rabizadeh, R. Xavier, M. Nedwidek, T. Chen, X. F. Zhang, B. Seed, and J. Avruch. 2002. Identification of a novel Ras-regulated proapoptotic pathway. Curr. Biol. 12:253-265.
-
(2002)
Curr. Biol.
, vol.12
, pp. 253-265
-
-
Khokhlatchev, A.1
Rabizadeh, S.2
Xavier, R.3
Nedwidek, M.4
Chen, T.5
Zhang, X.F.6
Seed, B.7
Avruch, J.8
-
29
-
-
33947099350
-
Nuclear transport of Ras-associated tumor suppressor proteins: Different transport receptor binding specificities for arginine-rich nuclear targeting signals
-
Kumari, G., P. K. Singhal, M. R. Rao, and S. Mahalingam. 2007. Nuclear transport of Ras-associated tumor suppressor proteins: different transport receptor binding specificities for arginine-rich nuclear targeting signals. J. Mol. Biol. 367:1294-1311.
-
(2007)
J. Mol. Biol.
, vol.367
, pp. 1294-1311
-
-
Kumari, G.1
Singhal, P.K.2
Rao, M.R.3
Mahalingam, S.4
-
30
-
-
40349103522
-
Hypermethylation of MCAM gene is associated with advanced tumor stage in prostate cancer
-
Liu, J. W., J. K. Nagpal, C. Jeronimo, J. E. Lee, R. Henrique, M. S. Kim, K. L. Ostrow, K. Yamashita, V. van Criekinge, G. Wu, C. S. Moon, B. Trink, and D. Sidransky. 2008. Hypermethylation of MCAM gene is associated with advanced tumor stage in prostate cancer. Prostate 68:418-426.
-
(2008)
Prostate
, vol.68
, pp. 418-426
-
-
Liu, J.W.1
Nagpal, J.K.2
Jeronimo, C.3
Lee, J.E.4
Henrique, R.5
Kim, M.S.6
Ostrow, K.L.7
Yamashita, K.8
Van Criekinge, V.9
Wu, G.10
Moon, C.S.11
Trink, B.12
Sidransky, D.13
-
31
-
-
0037805547
-
RAS oncogenes: The first 30 years
-
Malumbres, M., and M. Barbacid. 2003. RAS oncogenes: the first 30 years. Nat. Rev. Cancer 3:459-465.
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 459-465
-
-
Malumbres, M.1
Barbacid, M.2
-
32
-
-
49349109183
-
Cytoplasmic RASSF2A is a proapoptotic mediator whose expression is epigenetically silenced in gastric cancer
-
Maruyama, R., K. Akino, M. Toyota, H. Suzuki, T. Imai, M. Ohe-Toyota, E. Yamamoto, M. Nojima, T. Fujikane, Y. Sasaki, T. Yamashita, Y. Watanabe, H. Hiratsuka, K. Hirata, F. Itoh, K. Imai, Y. Shinomura, and T. Tokino. 2008. Cytoplasmic RASSF2A is a proapoptotic mediator whose expression is epigenetically silenced in gastric cancer. Carcinogenesis 29:1312-1318.
-
(2008)
Carcinogenesis
, vol.29
, pp. 1312-1318
-
-
Maruyama, R.1
Akino, K.2
Toyota, M.3
Suzuki, H.4
Imai, T.5
Ohe-Toyota, M.6
Yamamoto, E.7
Nojima, M.8
Fujikane, T.9
Sasaki, Y.10
Yamashita, T.11
Watanabe, Y.12
Hiratsuka, H.13
Hirata, K.14
Itoh, F.15
Imai, K.16
Shinomura, Y.17
Tokino, T.18
-
33
-
-
33947266099
-
Identification and validation of colorectal neoplasia-specific methylation markers for accurate classification of disease
-
Model, F., N. Osborn, D. Ahlquist, R. Gruetzmann, B. Molnar, F. Sipos, O. Galamb, C. Pilarsky, H. D. Saeger, Z. Tulassay, K. Hale, S. Mooney, J. Lograsso, P. Adorjan, R. Lesche, A. Dessauer, J. Kleiber, B. Porstmann, A. Sledziewski, and C. Lofton-Day. 2007. Identification and validation of colorectal neoplasia-specific methylation markers for accurate classification of disease. Mol. Cancer Res. 5:153-163.
-
(2007)
Mol. Cancer Res.
, vol.5
, pp. 153-163
-
-
Model, F.1
Osborn, N.2
Ahlquist, D.3
Gruetzmann, R.4
Molnar, B.5
Sipos, F.6
Galamb, O.7
Pilarsky, C.8
Saeger, H.D.9
Tulassay, Z.10
Hale, K.11
Mooney, S.12
Lograsso, J.13
Adorjan, P.14
Lesche, R.15
Dessauer, A.16
Kleiber, J.17
Porstmann, B.18
Sledziewski, A.19
Lofton-Day, C.20
more..
-
34
-
-
33947196921
-
Inactivation of the candidate tumor suppressor Par-4 in endometrial cancer
-
DOI 10.1158/0008-5472.CAN-06-2687
-
Moreno-Bueno, G., P. J. Fernandez-Marcos, M. Collado, M. J. Tendero, S. M. Rodriguez-Pinilla, I. Garcia-Cao, D. Hardisson, M. T. Diaz-Meco, J. Moscat, M. Serrano, and J. Palacios. 2007. Inactivation of the candidate tumor suppressor par-4 in endometrial cancer. Cancer Res. 67:1927-1934. (Pubitemid 46424208)
-
(2007)
Cancer Research
, vol.67
, Issue.5
, pp. 1927-1934
-
-
Moreno-Bueno, G.1
Fernandez-Marcos, P.J.2
Collado, M.3
Tendero, M.J.4
Rodriguez-Pinilla, S.M.5
Garcia-Cao, I.6
Hardisson, D.7
Diaz-Meco, M.T.8
Moscat, J.9
Serrano, M.10
Palacios, J.11
-
35
-
-
0033570123
-
Oncogenic Ras sensitizes cells to apoptosis by Par-4
-
Nalca, A., S. G. Qiu, N. El-Guendy, S. Krishnan, and V. M. Rangnekar. 1999. Oncogenic Ras sensitizes cells to apoptosis by Par-4. J. Biol. Chem. 274: 29976-29983.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 29976-29983
-
-
Nalca, A.1
Qiu, S.G.2
El-Guendy, N.3
Krishnan, S.4
Rangnekar, V.M.5
-
36
-
-
33845451110
-
Correlation between hypermethylation of the RASSF2A promoter and K-ras/BRAF mutations in microsatellite-stable colorectal cancers
-
Park, H. W., H. C. Kang, I. J. Kim, S. G. Jang, K. Kim, H. J. Yoon, S. Y. Jeong, and J. G. Park. 2007. Correlation between hypermethylation of the RASSF2A promoter and K-ras/BRAF mutations in microsatellite-stable colorectal cancers. Int. J. Cancer 120:7-12.
-
(2007)
Int. J. Cancer
, vol.120
, pp. 7-12
-
-
Park, H.W.1
Kang, H.C.2
Kim, I.J.3
Jang, S.G.4
Kim, K.5
Yoon, H.J.6
Jeong, S.Y.7
Park, J.G.8
-
37
-
-
58249105729
-
K-ras and Wnt signaling synergize to accelerate prostate tumorigenesis in the mouse
-
Pearson, H. B., T. J. Phesse, and A. R. Clarke. 2009. K-ras and Wnt signaling synergize to accelerate prostate tumorigenesis in the mouse. Cancer Res. 69:94-101.
-
(2009)
Cancer Res.
, vol.69
, pp. 94-101
-
-
Pearson, H.B.1
Phesse, T.J.2
Clarke, A.R.3
-
38
-
-
20744447485
-
Ras-mediated loss of the pro-apoptotic response protein Par-4 is mediated by DNA hypermethylation through Raf-independent and Raf-dependent signaling cascades in epithelial cells
-
Pruitt, K., A. S. Ulku, K. Frantz, R. J. Rojas, V. M. Muniz-Medina, V. M. Rangnekar, C. J. Der, and J. M. Shields. 2005. Ras-mediated loss of the pro-apoptotic response protein Par-4 is mediated by DNA hypermethylation through Raf-independent and Raf-dependent signaling cascades in epithelial cells. J. Biol. Chem. 280:23363-23370.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 23363-23370
-
-
Pruitt, K.1
Ulku, A.S.2
Frantz, K.3
Rojas, R.J.4
Muniz-Medina, V.M.5
Rangnekar, V.M.6
Der, C.J.7
Shields, J.M.8
-
39
-
-
0008881181
-
Mutually exclusive expression patterns of Bcl-2 and Par-4 in human prostate tumors consistent with down-regulation of Bcl-2 by Par-4
-
Qiu, G., M. Ahmed, S. F. Sells, M. Mohiuddin, M. H. Weinstein, and V. M. Rangnekar. 1999. Mutually exclusive expression patterns of Bcl-2 and Par-4 in human prostate tumors consistent with down-regulation of Bcl-2 by Par-4. Oncogene 18:623-631.
-
(1999)
Oncogene
, vol.18
, pp. 623-631
-
-
Qiu, G.1
Ahmed, M.2
Sells, S.F.3
Mohiuddin, M.4
Weinstein, M.H.5
Rangnekar, V.M.6
-
40
-
-
0030990094
-
Expression and function of the leucine zipper protein Par-4 in apoptosis
-
Sells, S. F., S. S. Han, S. Muthukkumar, N. Maddiwar, R. Johnstone, E. Boghaert, D. Gillis, G. Liu, P. Nair, S. Monnig, P. Collini, M. P. Mattson, V. P. Sukhatme, S. G. Zimmer, D. P. Wood, Jr., J. W. McRoberts, Y. Shi, and V. M. Rangnekar. 1997. Expression and function of the leucine zipper protein Par-4 in apoptosis. Mol. Cell. Biol. 17:3823-3832.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 3823-3832
-
-
Sells, S.F.1
Han, S.S.2
Muthukkumar, S.3
Maddiwar, N.4
Johnstone, R.5
Boghaert, E.6
Gillis, D.7
Liu, G.8
Nair, P.9
Monnig, S.10
Collini, P.11
Mattson, M.P.12
Sukhatme, V.P.13
Zimmer, S.G.14
Wood Jr., D.P.15
McRoberts, J.W.16
Shi, Y.17
Rangnekar, V.M.18
-
41
-
-
0028015669
-
Commonality of the gene programs induced by effectors of apoptosis in androgen-dependent and -independent prostate cells
-
Sells, S. F., D. P. Wood, Jr., S. S. Joshi-Barve, S. Muthukumar, R. J. Jacob, S. A. Crist, S. Humphreys, and V. M. Rangnekar. 1994. Commonality of the gene programs induced by effectors of apoptosis in androgen-dependent and -independent prostate cells. Cell Growth Differ. 5:457-466.
-
(1994)
Cell Growth Differ.
, vol.5
, pp. 457-466
-
-
Sells, S.F.1
Wood Jr., D.P.2
Joshi-Barve, S.S.3
Muthukumar, S.4
Jacob, R.J.5
Crist, S.A.6
Humphreys, S.7
Rangnekar, V.M.8
-
42
-
-
37549009969
-
Role of tumor necrosis factor-alpha and TRAIL in high-dose radiation-induced bystander signaling in lung adenocarcinoma
-
Shareef, M. M., N. Cui, R. Burikhanov, S. Gupta, S. Satishkumar, S. Shajahan, M. Mohiuddin, V. M. Rangnekar, and M. M. Ahmed. 2007. Role of tumor necrosis factor-alpha and TRAIL in high-dose radiation-induced bystander signaling in lung adenocarcinoma. Cancer Res. 67:11811-11820.
-
(2007)
Cancer Res.
, vol.67
, pp. 11811-11820
-
-
Shareef, M.M.1
Cui, N.2
Burikhanov, R.3
Gupta, S.4
Satishkumar, S.5
Shajahan, S.6
Mohiuddin, M.7
Rangnekar, V.M.8
Ahmed, M.M.9
-
43
-
-
19944429131
-
Tumor susceptibility of Rassf1a knockout mice
-
Tommasi, S., R. Dammann, Z. Zhang, Y. Wang, L. Liu, W. M. Tsark, S. P. Wilczynski, J. Li, M. You, and G. P. Pfeifer. 2005. Tumor susceptibility of Rassf1a knockout mice. Cancer Res. 65:92-98. (Pubitemid 40070799)
-
(2005)
Cancer Research
, vol.65
, Issue.1
, pp. 92-98
-
-
Tommasi, S.1
Dammann, R.2
Zhang, Z.3
Wang, Y.4
Liu, L.5
Tsark, W.M.6
Wilczynski, S.P.7
Li, J.8
You, M.9
Pfeifer, G.P.10
-
44
-
-
34548220076
-
The Ras-association domain family (RASSF) members and their role in human tumourigenesis
-
van der Weyden, L., and D. J. Adams. 2007. The Ras-association domain family (RASSF) members and their role in human tumourigenesis. Biochim. Biophys. Acta 1776:58-85.
-
(2007)
Biochim. Biophys. Acta
, vol.1776
, pp. 58-85
-
-
Van Der Weyden, L.1
Adams, D.J.2
-
45
-
-
33646194020
-
The RASSF1A tumor suppressor activates Bax via MOAP-1
-
Vos, M. D., A. Dallol, K. Eckfeld, N. P. Allen, H. Donninger, L. B. Hesson, D. Calvisi, F. Latif, and G. J. Clark. 2006. The RASSF1A tumor suppressor activates Bax via MOAP-1. J. Biol. Chem. 281:4557-4563.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 4557-4563
-
-
Vos, M.D.1
Dallol, A.2
Eckfeld, K.3
Allen, N.P.4
Donninger, H.5
Hesson, L.B.6
Calvisi, D.7
Latif, F.8
Clark, G.J.9
-
46
-
-
0034680870
-
Ras uses the novel tumor suppressor RASSF1 as an effector to mediate apoptosis
-
Vos, M. D., C. A. Ellis, A. Bell, M. J. Birrer, and G. J. Clark. 2000. Ras uses the novel tumor suppressor RASSF1 as an effector to mediate apoptosis. J. Biol. Chem. 275:35669-35672.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 35669-35672
-
-
Vos, M.D.1
Ellis, C.A.2
Bell, A.3
Birrer, M.J.4
Clark, G.J.5
-
47
-
-
0041845273
-
RASSF2 is a novel K-Ras-specific effector and potential tumor suppressor
-
Vos, M. D., C. A. Ellis, C. Elam, A. S. Ulku, B. J. Taylor, and G. J. Clark. 2003. RASSF2 is a novel K-Ras-specific effector and potential tumor suppressor. J. Biol. Chem. 278:28045-28051.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 28045-28051
-
-
Vos, M.D.1
Ellis, C.A.2
Elam, C.3
Ulku, A.S.4
Taylor, B.J.5
Clark, G.J.6
-
48
-
-
33845400874
-
Inactivation of RASSF2A by promoter methylation correlates with lymph node metastasis in nasopharyngeal carcinoma
-
Zhang, Z., D. Sun, N. Van do, A. Tang, L. Hu, and G. Huang. 2007. Inactivation of RASSF2A by promoter methylation correlates with lymph node metastasis in nasopharyngeal carcinoma. Int. J. Cancer. 120:32-38.
-
(2007)
Int. J. Cancer
, vol.120
, pp. 32-38
-
-
Zhang, Z.1
Sun, D.2
Van Do, N.3
Tang, A.4
Hu, L.5
Huang, G.6
-
49
-
-
35148859307
-
Cancer resistance in transgenic mice expressing the SAC module of Par-4
-
Zhao, Y., R. Burikhanov, S. Qiu, S. M. Lele, C. D. Jennings, S. Bondada, B. Spear, and V. M. Rangnekar. 2007. Cancer resistance in transgenic mice expressing the SAC module of Par-4. Cancer Res. 67:9276-9285.
-
(2007)
Cancer Res.
, vol.67
, pp. 9276-9285
-
-
Zhao, Y.1
Burikhanov, R.2
Qiu, S.3
Lele, S.M.4
Jennings, C.D.5
Bondada, S.6
Spear, B.7
Rangnekar, V.M.8
|