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Volumn 28, Issue 33, 2009, Pages 2988-2998

RASSF2 associates with and stabilizes the proapoptotic kinase MST2

Author keywords

Epigenetics; MST; MST2; Proteomics; RASSF2

Indexed keywords

BINDING PROTEIN; CARRIER PROTEINS AND BINDING PROTEINS; PROTEIN MST1; PROTEIN MST2; RAS ASSOCIATION DOMAIN FAMILY PROTEIN 2; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG;

EID: 69249217720     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2009.152     Document Type: Article
Times cited : (73)

References (39)
  • 1
    • 18144411303 scopus 로고    scopus 로고
    • Role of the rasassociation domain family 1 tumor suppressor gene in human cancers
    • Agathanggelou A, Cooper WN, Latif F. (2005). Role of the rasassociation domain family 1 tumor suppressor gene in human cancers. Cancer Res 65: 3497-3508.
    • (2005) Cancer Res , vol.65 , pp. 3497-3508
    • Agathanggelou, A.1    Cooper, W.N.2    Latif, F.3
  • 2
    • 33748308721 scopus 로고    scopus 로고
    • Association of mammalian sterile twenty kinases, Mst1 and Mst2, with hSalvador via C-terminal coiled-coil domains, leads to its stabilization and phosphorylation
    • Callus BA, Verhagen AM, Vaux DL. (2006). Association of mammalian sterile twenty kinases, Mst1 and Mst2, with hSalvador via C-terminal coiled-coil domains, leads to its stabilization and phosphorylation. FEBS J 273: 4264-4276.
    • (2006) FEBS J , vol.273 , pp. 4264-4276
    • Callus, B.A.1    Verhagen, A.M.2    Vaux, D.L.3
  • 3
    • 0038293152 scopus 로고    scopus 로고
    • Apoptotic phosphorylation of histone H2B is mediated by mammalian sterile twenty kinase
    • Cheung WL, Ajiro K, Samejima K, Kloc M, Cheung P, Mizzen CA et al. (2003). Apoptotic phosphorylation of histone H2B is mediated by mammalian sterile twenty kinase. Cell 113: 507-517.
    • (2003) Cell , vol.113 , pp. 507-517
    • Cheung, W.L.1    Ajiro, K.2    Samejima, K.3    Kloc, M.4    Cheung, P.5    Mizzen, C.A.6
  • 4
    • 40749133034 scopus 로고    scopus 로고
    • Epigenetic regulation of the ras effector/ tumour suppressor RASSF2 in breast and lung cancer
    • Cooper WN, Dickinson RE, Dallol A, Grigorieva EV, Pavlova TV, Hesson LB et al. (2008). Epigenetic regulation of the ras effector/ tumour suppressor RASSF2 in breast and lung cancer. Oncogene 27: 1805-1811.
    • (2008) Oncogene , vol.27 , pp. 1805-1811
    • Cooper, W.N.1    Dickinson, R.E.2    Dallol, A.3    Grigorieva, E.V.4    Pavlova, T.V.5    Hesson, L.B.6
  • 5
    • 0029788972 scopus 로고    scopus 로고
    • The Ste20-like protein kinase, Mst1, dimerizes and contains an inhibitory domain
    • Creasy CL, Ambrose DM, Chernoff J. (1996). The Ste20-like protein kinase, Mst1, dimerizes and contains an inhibitory domain. J Biol Chem 271: 21049-21053.
    • (1996) J Biol Chem , vol.271 , pp. 21049-21053
    • Creasy, C.L.1    Ambrose, D.M.2    Chernoff, J.3
  • 7
    • 0038485597 scopus 로고    scopus 로고
    • Regulation of mammalian STE20- like kinase 2 (MST2) by protein phosphorylation/dephosphorylation and proteolysis
    • Deng Y, Pang A, Wang JH. (2003). Regulation of mammalian STE20- like kinase 2 (MST2) by protein phosphorylation/dephosphorylation and proteolysis. J Biol Chem 278: 11760-11767.
    • (2003) J Biol Chem , vol.278 , pp. 11760-11767
    • Deng, Y.1    Pang, A.2    Wang, J.H.3
  • 8
    • 0037082158 scopus 로고    scopus 로고
    • High-level and highthroughput recombinant protein production by transient transfection of suspension-growing human 293-EBNA1 cells
    • Durocher Y, Perret S, Kamen A. (2002). High-level and highthroughput recombinant protein production by transient transfection of suspension-growing human 293-EBNA1 cells. Nucleic Acids Res 30: E9.
    • (2002) Nucleic Acids Res , vol.30
    • Durocher, Y.1    Perret, S.2    Kamen, A.3
  • 9
    • 28644450906 scopus 로고    scopus 로고
    • RASSF2, a potential tumour suppressor, is silenced by CpG island hypermethylation in gastric cancer
    • Endoh M, Tamura G, Honda T, Homma N, Terashima M, Nishizuka S et al. (2005). RASSF2, a potential tumour suppressor, is silenced by CpG island hypermethylation in gastric cancer. Br J Cancer 93: 1395-1399.
    • (2005) Br J Cancer , vol.93 , pp. 1395-1399
    • Endoh, M.1    Tamura, G.2    Honda, T.3    Homma, N.4    Terashima, M.5    Nishizuka, S.6
  • 10
    • 9144262332 scopus 로고    scopus 로고
    • Identification of the E1Aregulated transcription factor p120(E4F) as an interacting partner of the RASSF1A candidate tumor suppressor gene
    • Fenton SL, Dallol A, Agathanggelou A, Hesson L, Ahmed- Choudhury J, Baksh S et al. (2004). Identification of the E1Aregulated transcription factor p120(E4F) as an interacting partner of the RASSF1A candidate tumor suppressor gene. Cancer Res 64: 102-107.
    • (2004) Cancer Res , vol.64 , pp. 102-107
    • Fenton, S.L.1    Dallol, A.2    Agathanggelou, A.3    Hesson, L.4    Ahmed- Choudhury, J.5    Baksh, S.6
  • 11
    • 0037044808 scopus 로고    scopus 로고
    • Mapping of MST1 kinase sites of phosphorylation. Activation and autophosphorylation
    • Glantschnig H, Rodan GA, Reszka AA. (2002). Mapping of MST1 kinase sites of phosphorylation. Activation and autophosphorylation. J Biol Chem 277: 42987-42996.
    • (2002) J Biol Chem , vol.277 , pp. 42987-42996
    • Glantschnig, H.1    Rodan, G.A.2    Reszka, A.A.3
  • 12
    • 0035805593 scopus 로고    scopus 로고
    • Both phosphorylation and caspase-mediated cleavage contribute to regulation of the Ste20-like protein kinase Mst1 during CD95/ Fas-induced apoptosis
    • Graves JD, Draves KE, Gotoh Y, Krebs EG, Clark EA. (2001). Both phosphorylation and caspase-mediated cleavage contribute to regulation of the Ste20-like protein kinase Mst1 during CD95/ Fas-induced apoptosis. J Biol Chem 276: 14909-14915.
    • (2001) J Biol Chem , vol.276 , pp. 14909-14915
    • Graves, J.D.1    Draves, K.E.2    Gotoh, Y.3    Krebs, E.G.4    Clark, E.A.5
  • 13
    • 0032522704 scopus 로고    scopus 로고
    • Caspase-mediated activation and induction of apoptosis by the mammalian Ste20-like kinase Mst1
    • Graves JD, Gotoh Y, Draves KE, Ambrose D, Han DKM, Wright M et al. (1998). Caspase-mediated activation and induction of apoptosis by the mammalian Ste20-like kinase Mst1. EMBO J 17: 2224-2234.
    • (1998) EMBO J , vol.17 , pp. 2224-2234
    • Graves, J.D.1    Gotoh, Y.2    Draves, K.E.3    Ambrose, D.4    Han, D.K.M.5    Wright, M.6
  • 14
    • 34047250808 scopus 로고    scopus 로고
    • RASSF1A is part of a complex similar to the Drosophila Hippo/ Salvador/Lats tumor-suppressor network
    • Guo C, Tommasi S, Liu L, Yee JK, Dammann R, Pfeifer GP. (2007). RASSF1A is part of a complex similar to the Drosophila Hippo/ Salvador/Lats tumor-suppressor network. Curr Biol 17: 700-705.
    • (2007) Curr Biol , vol.17 , pp. 700-705
    • Guo, C.1    Tommasi, S.2    Liu, L.3    Yee, J.K.4    Dammann, R.5    Pfeifer, G.P.6
  • 15
    • 20544445183 scopus 로고    scopus 로고
    • CpG island promoter hypermethylation of a novel Ras-effector gene RASSF2A is an early event in colon carcinogenesis and correlates inversely with K-ras mutations
    • Hesson LB, Wilson R, Morton D, Adams C, Walker M, Maher ER et al. (2005). CpG island promoter hypermethylation of a novel Ras-effector gene RASSF2A is an early event in colon carcinogenesis and correlates inversely with K-ras mutations. Oncogene 24: 3987-3994.
    • (2005) Oncogene , vol.24 , pp. 3987-3994
    • Hesson, L.B.1    Wilson, R.2    Morton, D.3    Adams, C.4    Walker, M.5    Maher, E.R.6
  • 16
    • 36249025726 scopus 로고    scopus 로고
    • Acinus-provoked protein kinase C delta isoform activation is essential for apoptotic chromatin condensation
    • Hu Y, Liu Z, Yang SJ, Ye K. (2007). Acinus-provoked protein kinase C delta isoform activation is essential for apoptotic chromatin condensation. Cell Death Differ 14: 2035-2046.
    • (2007) Cell Death Differ , vol.14 , pp. 2035-2046
    • Hu, Y.1    Liu, Z.2    Yang, S.J.3    Ye, K.4
  • 17
    • 34547162995 scopus 로고    scopus 로고
    • Structural insight into dimeric interaction of the SARAH domains from Mst1 and RASSF family proteins in the apoptosis pathway
    • Hwang E, Ryu KS, Paakkonen K, Guntert P, Cheong HK, Lim DS et al. (2007). Structural insight into dimeric interaction of the SARAH domains from Mst1 and RASSF family proteins in the apoptosis pathway. Proc Natl Acad Sci USA 104: 9236-9241.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 9236-9241
    • Hwang, E.1    Ryu, K.S.2    Paakkonen, K.3    Guntert, P.4    Cheong, H.K.5    Lim, D.S.6
  • 18
    • 43649098854 scopus 로고    scopus 로고
    • Epigenetic inactivation of RASSF2 in oral squamous cell carcinoma
    • Imai T, Toyota M, Suzuki H, Akino K, Ogi K, Sogabe Y et al. (2008). Epigenetic inactivation of RASSF2 in oral squamous cell carcinoma. Cancer Sci 99: 958-966.
    • (2008) Cancer Sci , vol.99 , pp. 958-966
    • Imai, T.1    Toyota, M.2    Suzuki, H.3    Akino, K.4    Ogi, K.5    Sogabe, Y.6
  • 20
    • 0032212459 scopus 로고    scopus 로고
    • Caspase-mediated activation of a 36-kDa myelin basic protein kinase during anticancer drug-induced apoptosis
    • Kakeya H, Onose R, Osada H. (1998). Caspase-mediated activation of a 36-kDa myelin basic protein kinase during anticancer drug-induced apoptosis. Cancer Res 58: 4888-4894.
    • (1998) Cancer Res , vol.58 , pp. 4888-4894
    • Kakeya, H.1    Onose, R.2    Osada, H.3
  • 22
    • 60349101656 scopus 로고    scopus 로고
    • Mapping of signaling pathways by functional interaction proteomics
    • Kriegsheim A, Preisinger C, Kolch W. (2008). Mapping of signaling pathways by functional interaction proteomics. Methods Mol Biol 484: 177-192.
    • (2008) Methods Mol Biol , vol.484 , pp. 177-192
    • Kriegsheim, A.1    Preisinger, C.2    Kolch, W.3
  • 23
    • 33947099350 scopus 로고    scopus 로고
    • Nuclear transport of Ras-associated tumor suppressor proteins: Different transport receptor binding specificities for arginine-rich nuclear targeting signals
    • Kumari G, Singhal PK, Rao MR, Mahalingam S. (2007). Nuclear transport of Ras-associated tumor suppressor proteins: different transport receptor binding specificities for arginine-rich nuclear targeting signals. J Mol Biol 367: 1294-1311.
    • (2007) J Mol Biol , vol.367 , pp. 1294-1311
    • Kumari, G.1    Singhal, P.K.2    Rao, M.R.3    Mahalingam, S.4
  • 24
    • 58049194223 scopus 로고    scopus 로고
    • The growth and tumor suppressors NORE1A and RASSF1A are targets for calpainmediated proteolysis
    • Kuznetsov S, Khokhlatchev AV. (2008). The growth and tumor suppressors NORE1A and RASSF1A are targets for calpainmediated proteolysis. PLoS ONE 3: e3997.
    • (2008) PLoS ONE , vol.3
    • Kuznetsov, S.1    Khokhlatchev, A.V.2
  • 25
    • 0035379556 scopus 로고    scopus 로고
    • MST, a physiological caspase substrate, highly sensitizes apoptosis both upstream and downstream of caspase activation
    • Lee KK, Ohyama T, Yajima N, Tsubuki S, Yonehara S. (2001). MST, a physiological caspase substrate, highly sensitizes apoptosis both upstream and downstream of caspase activation. J Biol Chem 276: 19276-19285.
    • (2001) J Biol Chem , vol.276 , pp. 19276-19285
    • Lee, K.K.1    Ohyama, T.2    Yajima, N.3    Tsubuki, S.4    Yonehara, S.5
  • 26
    • 0037023722 scopus 로고    scopus 로고
    • Phosphorylation and dimerization regulate nucleocytoplasmic shuttling of mammalian STE20-like kinase (MST)
    • Lee KK, Yonehara S. (2002). Phosphorylation and dimerization regulate nucleocytoplasmic shuttling of mammalian STE20-like kinase (MST). J Biol Chem 277: 12351-12358.
    • (2002) J Biol Chem , vol.277 , pp. 12351-12358
    • Lee, K.K.1    Yonehara, S.2
  • 27
    • 44949106316 scopus 로고    scopus 로고
    • Hypermethylation of RAS effector related genes and DNA methyltransferase 1 expression in endometrial carcinogenesis
    • Liao X, Siu MK, Chan KY, Wong ES, Ngan HY, Chan QK et al. (2008). Hypermethylation of RAS effector related genes and DNA methyltransferase 1 expression in endometrial carcinogenesis. Int J Cancer 123: 296-302.
    • (2008) Int J Cancer , vol.123 , pp. 296-302
    • Liao, X.1    Siu, M.K.2    Chan, K.Y.3    Wong, E.S.4    Ngan, H.Y.5    Chan, Q.K.6
  • 28
    • 0037073794 scopus 로고    scopus 로고
    • Death-associated protein 4 binds MST1 and augments MST1-induced apoptosis
    • Lin Y, Khokhlatchev A, Figeys D, Avruch J. (2002). Death-associated protein 4 binds MST1 and augments MST1-induced apoptosis. J Biol Chem 277: 47991-48001.
    • (2002) J Biol Chem , vol.277 , pp. 47991-48001
    • Lin, Y.1    Khokhlatchev, A.2    Figeys, D.3    Avruch, J.4
  • 29
    • 49349109183 scopus 로고    scopus 로고
    • Cytoplasmic RASSF2A is a pro-apoptotic mediator whose expression is epigenetically silenced in gastric cancer
    • Maruyama R, Akino K, Toyota M, Suzuki H, Imai T, Ohe-Toyota M et al. (2008). Cytoplasmic RASSF2A is a pro-apoptotic mediator whose expression is epigenetically silenced in gastric cancer. Carcinogenesis.
    • (2008) Carcinogenesis
    • Maruyama, R.1    Akino, K.2    Toyota, M.3    Suzuki, H.4    Imai, T.5    Ohe-Toyota, M.6
  • 30
    • 11144267126 scopus 로고    scopus 로고
    • Role of the kinase MST2 in suppression of apoptosis by the proto-oncogene product Raf-1
    • O'Neill E, Rushworth L, Baccarini M, Kolch W. (2004). Role of the kinase MST2 in suppression of apoptosis by the proto-oncogene product Raf-1. Science 306: 2267-2270.
    • (2004) Science , vol.306 , pp. 2267-2270
    • O'Neill, E.1    Rushworth, L.2    Baccarini, M.3    Kolch, W.4
  • 31
    • 33645050117 scopus 로고    scopus 로고
    • Role of the tumor suppressor RASSF1A in Mst1-mediated apoptosis
    • Oh HJ, Lee KK, Song SJ, Jin MS, Song MS, Lee JH et al. (2006). Role of the tumor suppressor RASSF1A in Mst1-mediated apoptosis. Cancer Res 66: 2562-2569.
    • (2006) Cancer Res , vol.66 , pp. 2562-2569
    • Oh, H.J.1    Lee, K.K.2    Song, S.J.3    Jin, M.S.4    Song, M.S.5    Lee, J.H.6
  • 32
    • 3242794878 scopus 로고    scopus 로고
    • Regulation of the MST1 kinase by autophosphorylation, by the growth inhibitory proteins, RASSF1 and NORE1, and by Ras
    • Praskova M, Khoklatchev A, Ortiz-Vega S, Avruch J. (2004). Regulation of the MST1 kinase by autophosphorylation, by the growth inhibitory proteins, RASSF1 and NORE1, and by Ras. Biochem J 381: 453-462.
    • (2004) Biochem J , vol.381 , pp. 453-462
    • Praskova, M.1    Khoklatchev, A.2    Ortiz-Vega, S.3    Avruch, J.4
  • 33
    • 3142710380 scopus 로고    scopus 로고
    • The scaffold protein CNK1 interacts with the tumor suppressor RASSF1A and augments RASSF1Ainduced cell death
    • Rabizadeh S, Xavier RJ, Ishiguro K, Bernabeortiz J, Lopez-IlasacaM, Khokhlatchev A et al. (2004). The scaffold protein CNK1 interacts with the tumor suppressor RASSF1A and augments RASSF1Ainduced cell death. J Biol Chem 279: 29247-29254.
    • (2004) J Biol Chem , vol.279 , pp. 29247-29254
    • Rabizadeh, S.1    Xavier, R.J.2    Ishiguro, K.3    Bernabeortiz, J.4    IlasacaM, L.5    Khokhlatchev, A.6
  • 34
    • 0033520927 scopus 로고    scopus 로고
    • Bisphosphonates act directly on the osteoclast to induce caspase cleavage of mst1 kinase during apoptosis. A link between inhibition of the mevalonate pathway and regulation of an apoptosispromoting kinase
    • Reszka AA, Halasy-Nagy JM, Masarachia PJ, Rodan GA. (1999). Bisphosphonates act directly on the osteoclast to induce caspase cleavage of mst1 kinase during apoptosis. A link between inhibition of the mevalonate pathway and regulation of an apoptosispromoting kinase. J Biol Chem 274: 34967-34973.
    • (1999) J Biol Chem , vol.274 , pp. 34967-34973
    • Reszka, A.A.1    Halasy-Nagy, J.M.2    Masarachia, P.J.3    Rodan, G.A.4
  • 35
    • 0345526420 scopus 로고    scopus 로고
    • A novel interaction motif, SARAH, connects three classes of tumor suppressor
    • Scheel H, Hofmann K. (2003). A novel interaction motif, SARAH, connects three classes of tumor suppressor. Curr Biol 13: R899-900.
    • (2003) Curr Biol , vol.13
    • Scheel, H.1    Hofmann, K.2
  • 36
    • 0035964190 scopus 로고    scopus 로고
    • Caspase cleavage of MST1 promotes nuclear translocation and chromatin condensation
    • Ura S, Masuyama N, Graves JD, Gotoh Y. (2001). Caspase cleavage of MST1 promotes nuclear translocation and chromatin condensation. Proc Natl Acad Sci USA 98: 10148-10153.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 10148-10153
    • Ura, S.1    Masuyama, N.2    Graves, J.D.3    Gotoh, Y.4
  • 37
    • 34547161916 scopus 로고    scopus 로고
    • Activation of the c-Jun N-terminal kinase pathway by MST1 is essential and sufficient for the induction of chromatin condensation during apoptosis
    • Ura S, Nishina H, Gotoh Y, Katada T. (2007). Activation of the c-Jun N-terminal kinase pathway by MST1 is essential and sufficient for the induction of chromatin condensation during apoptosis. Mol Cell Biol 27: 5514-5522.
    • (2007) Mol Cell Biol , vol.27 , pp. 5514-5522
    • Ura, S.1    Nishina, H.2    Gotoh, Y.3    Katada, T.4
  • 39
    • 0041845273 scopus 로고    scopus 로고
    • RASSF2 is a novel K-Ras-specific effector and potential tumor suppressor
    • Vos MD, Ellis CA, Elam C, Ulku AS, Taylor BJ, Clark GJ. (2003). RASSF2 is a novel K-Ras-specific effector and potential tumor suppressor. J Biol Chem 278: 28045-28051.
    • (2003) J Biol Chem , vol.278 , pp. 28045-28051
    • Vos, M.D.1    Ellis, C.A.2    Elam, C.3    Ulku, A.S.4    Taylor, B.J.5    Clark, G.J.6


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