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Volumn 46, Issue 9, 2010, Pages 1735-1743

Severe hypocholesterolaemia is often neglected in haematological malignancies

Author keywords

Cancer; Hypocholesterolaemia; Leukaemia; Lymphoma; Mevastatin

Indexed keywords

CHOLESTEROL; COMPACTIN; HYPOCHOLESTEROLEMIC AGENT; MEVINOLIN;

EID: 77952582310     PISSN: 09598049     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejca.2010.03.041     Document Type: Article
Times cited : (21)

References (45)
  • 2
    • 0035922201 scopus 로고    scopus 로고
    • Cholesterol catabolism in patients with acute myelogenous leukemia and hypocholesterolemia: suppressed levels of a circulating marker for bile acid synthesis
    • Tatidis L., Vitols S., Gruber A., Paul C., and Axelson M. Cholesterol catabolism in patients with acute myelogenous leukemia and hypocholesterolemia: suppressed levels of a circulating marker for bile acid synthesis. Cancer Lett 170 (2001) 169-175
    • (2001) Cancer Lett , vol.170 , pp. 169-175
    • Tatidis, L.1    Vitols, S.2    Gruber, A.3    Paul, C.4    Axelson, M.5
  • 3
    • 0022384877 scopus 로고
    • Hypocholesterolaemia in malignancy due to elevated low-density-lipoprotein-receptor activity in tumour cells: evidence from studies in patients with leukaemia
    • Vitols S., Gahrton G., Björkholm M., and Peterson C. Hypocholesterolaemia in malignancy due to elevated low-density-lipoprotein-receptor activity in tumour cells: evidence from studies in patients with leukaemia. Lancet 2 (1985) 1150-1154
    • (1985) Lancet , vol.2 , pp. 1150-1154
    • Vitols, S.1    Gahrton, G.2    Björkholm, M.3    Peterson, C.4
  • 4
    • 33746851152 scopus 로고    scopus 로고
    • Low levels of serum cholesterol/phospholipids are associated with the antiphospholipid antibodies in monoclonal gammopathy
    • Pugliese L., Bernardini I., Viola-Magni M.P., and Albi E. Low levels of serum cholesterol/phospholipids are associated with the antiphospholipid antibodies in monoclonal gammopathy. Int J Immunopathol Pharmacol 19 (2006) 331-337
    • (2006) Int J Immunopathol Pharmacol , vol.19 , pp. 331-337
    • Pugliese, L.1    Bernardini, I.2    Viola-Magni, M.P.3    Albi, E.4
  • 6
    • 0021281136 scopus 로고
    • Relationship between mevalonate and mitogenesis in human fibroblasts stimulated with platelet-derived growth factor
    • Fairbanks K.P., Witte L.D., and Goodman D.S. Relationship between mevalonate and mitogenesis in human fibroblasts stimulated with platelet-derived growth factor. J Biol Chem 259 (1984) 1546-1551
    • (1984) J Biol Chem , vol.259 , pp. 1546-1551
    • Fairbanks, K.P.1    Witte, L.D.2    Goodman, D.S.3
  • 8
    • 0023105070 scopus 로고
    • HMP-shunt and cholesterol metabolism in experimental models involving normal and preneoplastic liver growth
    • Columbano A., Dessi S., Ledda-Columbano G.M., et al. HMP-shunt and cholesterol metabolism in experimental models involving normal and preneoplastic liver growth. Toxicol Pathol 15 (1987) 43-50
    • (1987) Toxicol Pathol , vol.15 , pp. 43-50
    • Columbano, A.1    Dessi, S.2    Ledda-Columbano, G.M.3
  • 9
    • 0034930259 scopus 로고    scopus 로고
    • HMG-CoA reductase inhibitor mevastatin enhances the growth inhibitory effect of butyrate in the colorectal carcinoma cell line Caco-2
    • Wachtershauser A., Akoglu B., and Stein J. HMG-CoA reductase inhibitor mevastatin enhances the growth inhibitory effect of butyrate in the colorectal carcinoma cell line Caco-2. Carcinogenesis 22 (2001) 1061-1067
    • (2001) Carcinogenesis , vol.22 , pp. 1061-1067
    • Wachtershauser, A.1    Akoglu, B.2    Stein, J.3
  • 10
    • 0037062481 scopus 로고    scopus 로고
    • 3-Hydroxy-3-methylglutaryl CoA reductase inhibitors prevent high glucose-induced proliferation of mesangial cells via modulation of Rho GTPase/ p21 signaling pathway: Implications for diabetic nephropathy
    • Danesh F.R., Sadeghi M.M., Amro N., et al. 3-Hydroxy-3-methylglutaryl CoA reductase inhibitors prevent high glucose-induced proliferation of mesangial cells via modulation of Rho GTPase/ p21 signaling pathway: Implications for diabetic nephropathy. Proc Natl Acad Sci USA 99 (2002) 8301-8305
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 8301-8305
    • Danesh, F.R.1    Sadeghi, M.M.2    Amro, N.3
  • 11
    • 33846348016 scopus 로고    scopus 로고
    • Pleiotropic effects of statins and related pharmacological experimental approaches
    • Alegret M., and Silvestre J.S. Pleiotropic effects of statins and related pharmacological experimental approaches. Meth Find Exp Clin Pharmacol 28 (2006) 627-656
    • (2006) Meth Find Exp Clin Pharmacol , vol.28 , pp. 627-656
    • Alegret, M.1    Silvestre, J.S.2
  • 12
    • 57249115882 scopus 로고    scopus 로고
    • Simvastatin suppresses the differentiation of C2C12 myoblast cells via a Rac pathway
    • Baba T.T., Nemoto T.K., Miyazaki T., and Oida S. Simvastatin suppresses the differentiation of C2C12 myoblast cells via a Rac pathway. J Muscle Res Cell Motil 29 (2008) 127-134
    • (2008) J Muscle Res Cell Motil , vol.29 , pp. 127-134
    • Baba, T.T.1    Nemoto, T.K.2    Miyazaki, T.3    Oida, S.4
  • 13
    • 0032562672 scopus 로고    scopus 로고
    • Analogs of farnesylcysteine induce apoptosis in HL-60 cells
    • Pérez-Sala D., Gilbert B.A., Rando R.R., and Cañada F.J. Analogs of farnesylcysteine induce apoptosis in HL-60 cells. FEBS Lett 426 (1998) 319-324
    • (1998) FEBS Lett , vol.426 , pp. 319-324
    • Pérez-Sala, D.1    Gilbert, B.A.2    Rando, R.R.3    Cañada, F.J.4
  • 14
    • 0035114219 scopus 로고    scopus 로고
    • Lovastatin induces apoptosis of spontaneously immortalized rat brain neuroblasts: involvement of nonsterol isoprenoid biosynthesis inhibition
    • García-Román N., Alvarez A.M., Toro M.J., Montes A., and Lorenzo M.J. Lovastatin induces apoptosis of spontaneously immortalized rat brain neuroblasts: involvement of nonsterol isoprenoid biosynthesis inhibition. Mol Cell Neurosci 17 (2001) 329-341
    • (2001) Mol Cell Neurosci , vol.17 , pp. 329-341
    • García-Román, N.1    Alvarez, A.M.2    Toro, M.J.3    Montes, A.4    Lorenzo, M.J.5
  • 16
    • 33748979745 scopus 로고    scopus 로고
    • Invadopodia: specialized cell structures for cancer invasion
    • Weaver A.M. Invadopodia: specialized cell structures for cancer invasion. Clin Exp Metastasis 23 (2006) 97-105
    • (2006) Clin Exp Metastasis , vol.23 , pp. 97-105
    • Weaver, A.M.1
  • 17
    • 66449128339 scopus 로고    scopus 로고
    • Invadopodia biogenesis is regulated by caveolin-mediated modulation of membrane cholesterol levels
    • Caldieri G., Giacchetti G., Beznoussenko G., et al. Invadopodia biogenesis is regulated by caveolin-mediated modulation of membrane cholesterol levels. J Cell Mol Med 13 (2009) 1728-1740
    • (2009) J Cell Mol Med , vol.13 , pp. 1728-1740
    • Caldieri, G.1    Giacchetti, G.2    Beznoussenko, G.3
  • 18
    • 47849097390 scopus 로고    scopus 로고
    • Cholesterol and cholesterol-rich membranes in prostate cancer: an update
    • Di Vizio D., Solomon K.R., and Freeman M.R. Cholesterol and cholesterol-rich membranes in prostate cancer: an update. Tumori 94 (2008) 633-639
    • (2008) Tumori , vol.94 , pp. 633-639
    • Di Vizio, D.1    Solomon, K.R.2    Freeman, M.R.3
  • 19
    • 77951665350 scopus 로고    scopus 로고
    • Cisplatin-induced apoptosis involves a Fas-ROCK-ezrin-dependent actin remodelling in human colon cancer cells
    • [Epub ahead of print]
    • Rebillard A., Jouan-Lanhouet S., Jouan E., et al. Cisplatin-induced apoptosis involves a Fas-ROCK-ezrin-dependent actin remodelling in human colon cancer cells. Eur J Cancer (2010) [Epub ahead of print]
    • (2010) Eur J Cancer
    • Rebillard, A.1    Jouan-Lanhouet, S.2    Jouan, E.3
  • 20
    • 34548843672 scopus 로고    scopus 로고
    • Localization of the human breast cancer resistance protein (BCRP/ABCG2) in lipid rafts/caveolae and modulation of its activity by cholesterol in vitro
    • Storch C.H., Ehehalt R., Haefeli W.E., and Weiss J. Localization of the human breast cancer resistance protein (BCRP/ABCG2) in lipid rafts/caveolae and modulation of its activity by cholesterol in vitro. J Pharmacol Exp Ther 323 (2007) 257-264
    • (2007) J Pharmacol Exp Ther , vol.323 , pp. 257-264
    • Storch, C.H.1    Ehehalt, R.2    Haefeli, W.E.3    Weiss, J.4
  • 21
    • 48549093785 scopus 로고    scopus 로고
    • Mitochondrial cholesterol contributes to chemotherapy resistance in hepatocellular carcinoma
    • Montero J., Morales A., Llacuna L., et al. Mitochondrial cholesterol contributes to chemotherapy resistance in hepatocellular carcinoma. Cancer Res 68 (2008) 5246-5256
    • (2008) Cancer Res , vol.68 , pp. 5246-5256
    • Montero, J.1    Morales, A.2    Llacuna, L.3
  • 22
    • 46149098344 scopus 로고    scopus 로고
    • LXR signaling couples sterol metabolism to proliferation in the acquired immune response
    • Bensinger S.J., Bradley M.N., Joseph S.B., et al. LXR signaling couples sterol metabolism to proliferation in the acquired immune response. Cell 134 (2008) 97-111
    • (2008) Cell , vol.134 , pp. 97-111
    • Bensinger, S.J.1    Bradley, M.N.2    Joseph, S.B.3
  • 23
    • 36148989553 scopus 로고    scopus 로고
    • Low serum LDL cholesterol levels and the risk of fever, sepsis, and malignancy
    • Shor R., Wainstein J., Oz D., et al. Low serum LDL cholesterol levels and the risk of fever, sepsis, and malignancy. Ann Clin Lab Sci 37 (2007) 343-348
    • (2007) Ann Clin Lab Sci , vol.37 , pp. 343-348
    • Shor, R.1    Wainstein, J.2    Oz, D.3
  • 25
    • 0017744278 scopus 로고
    • Separation of lymphocytes, lymphocyte subgroups and monocytes: a review
    • Boyum A. Separation of lymphocytes, lymphocyte subgroups and monocytes: a review. Lymphology 10 (1977) 71-76
    • (1977) Lymphology , vol.10 , pp. 71-76
    • Boyum, A.1
  • 26
    • 33847141895 scopus 로고    scopus 로고
    • Sphingomyelin-cholesterol and double stranded RNA relationship in the intranuclear complex
    • Rossi G., Magni M.V., and Albi E. Sphingomyelin-cholesterol and double stranded RNA relationship in the intranuclear complex. Arch Biochem Biophys 459 (2007) 27-32
    • (2007) Arch Biochem Biophys , vol.459 , pp. 27-32
    • Rossi, G.1    Magni, M.V.2    Albi, E.3
  • 27
    • 20444400263 scopus 로고    scopus 로고
    • Nuclear sphingomyelin-synthase and protein kinase C delta in melanoma cells
    • Albi E., La Porta C.A.M., Castaldi S., and Viola Magni M. Nuclear sphingomyelin-synthase and protein kinase C delta in melanoma cells. Arch Biochem Biophys 438 (2005) 156-161
    • (2005) Arch Biochem Biophys , vol.438 , pp. 156-161
    • Albi, E.1    La Porta, C.A.M.2    Castaldi, S.3    Viola Magni, M.4
  • 28
    • 28444483923 scopus 로고    scopus 로고
    • Nuclear sphingomyelin pathway in serum deprivation-induced apoptosis of embryonic hippocampal cells
    • Albi E., Cataldi S., Bartoccini E., et al. Nuclear sphingomyelin pathway in serum deprivation-induced apoptosis of embryonic hippocampal cells. J Cell Physiol 206 (2006) 189-195
    • (2006) J Cell Physiol , vol.206 , pp. 189-195
    • Albi, E.1    Cataldi, S.2    Bartoccini, E.3
  • 30
    • 73549085851 scopus 로고    scopus 로고
    • In vivo evidence of duality effects for lovastatin in a nude mouse cancer model
    • Wang C.Y., Shui H.A., and Chang T.C. In vivo evidence of duality effects for lovastatin in a nude mouse cancer model. Int J Cancer 126 (2010) 578-582
    • (2010) Int J Cancer , vol.126 , pp. 578-582
    • Wang, C.Y.1    Shui, H.A.2    Chang, T.C.3
  • 31
    • 38949101159 scopus 로고    scopus 로고
    • Tumor-infiltrated immune response correlates with alterations in the apoptotic and cell cycle pathways in Hodgkin and Reed-Sternberg cells
    • Alvaro T., Lejeune M., García J.F., et al. Tumor-infiltrated immune response correlates with alterations in the apoptotic and cell cycle pathways in Hodgkin and Reed-Sternberg cells. Clin Cancer Res 14 (2008) 6856-6891
    • (2008) Clin Cancer Res , vol.14 , pp. 6856-6891
    • Alvaro, T.1    Lejeune, M.2    García, J.F.3
  • 32
    • 27144434812 scopus 로고    scopus 로고
    • Transcription inhibition by flavopiridol: mechanism of chronic lymphocytic leukemia cell death
    • Chen R., Keating M.J., Gandhi V., and Plunkett W. Transcription inhibition by flavopiridol: mechanism of chronic lymphocytic leukemia cell death. Blood 106 (2005) 2513-2519
    • (2005) Blood , vol.106 , pp. 2513-2519
    • Chen, R.1    Keating, M.J.2    Gandhi, V.3    Plunkett, W.4
  • 33
    • 55849121546 scopus 로고    scopus 로고
    • Signal transduction pathways of mantle cell lymphoma: a phosphoproteome-based study
    • Cecconi D., Zamò A., Bianchi E., et al. Signal transduction pathways of mantle cell lymphoma: a phosphoproteome-based study. Proteomic 8 (2008) 4495-4506
    • (2008) Proteomic , vol.8 , pp. 4495-4506
    • Cecconi, D.1    Zamò, A.2    Bianchi, E.3
  • 34
    • 33748477701 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma promotes lymphocyte survival through its actions on cellular metabolic activities
    • Jo S.H., Yang C., Miao Q., et al. Peroxisome proliferator-activated receptor gamma promotes lymphocyte survival through its actions on cellular metabolic activities. J Immunol 177 (2006) 3737-3745
    • (2006) J Immunol , vol.177 , pp. 3737-3745
    • Jo, S.H.1    Yang, C.2    Miao, Q.3
  • 35
    • 67349168710 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma overexpression and knockdown: impact on human B cell lymphoma proliferation and serviva
    • Garcia-Bates T.M., Peslak S.A., Baglole C.J., et al. Peroxisome proliferator-activated receptor gamma overexpression and knockdown: impact on human B cell lymphoma proliferation and serviva. Cancer Immunol Immunother 58 (2009) 1071-1083
    • (2009) Cancer Immunol Immunother , vol.58 , pp. 1071-1083
    • Garcia-Bates, T.M.1    Peslak, S.A.2    Baglole, C.J.3
  • 36
    • 42549139335 scopus 로고    scopus 로고
    • Apoptosis induced by an alkylated purine, 6-dimethylaminopurine, and changes in gene expression in human lymphoma U937 cells
    • Nakashima M., Cui Z.G., Tabuchi Y., et al. Apoptosis induced by an alkylated purine, 6-dimethylaminopurine, and changes in gene expression in human lymphoma U937 cells. Anticancer Res 28 (2008) 609-620
    • (2008) Anticancer Res , vol.28 , pp. 609-620
    • Nakashima, M.1    Cui, Z.G.2    Tabuchi, Y.3
  • 37
    • 33845270588 scopus 로고    scopus 로고
    • Characterization of an HMG-CoA reductase from Listeria monocytogenes that exhibits dual coenzyme specificità
    • Theivagt A.E., Amanti E.N., Beresford N.J., Tabernero L., and Friesen J.A. Characterization of an HMG-CoA reductase from Listeria monocytogenes that exhibits dual coenzyme specificità. Biochemistry 45 (2006) 14397-14406
    • (2006) Biochemistry , vol.45 , pp. 14397-14406
    • Theivagt, A.E.1    Amanti, E.N.2    Beresford, N.J.3    Tabernero, L.4    Friesen, J.A.5
  • 38
    • 4444257328 scopus 로고    scopus 로고
    • Cholesterol synthesis and import contribute to protective cholesterol increments in acute myeloid leukemia cells
    • Banker D.E., Mayer S.J., Li H.Y., et al. Cholesterol synthesis and import contribute to protective cholesterol increments in acute myeloid leukemia cells. Blood 104 (2004) 1816-1824
    • (2004) Blood , vol.104 , pp. 1816-1824
    • Banker, D.E.1    Mayer, S.J.2    Li, H.Y.3
  • 39
    • 0028784203 scopus 로고
    • Regulation of cholesterol synthesis in four colonic adenocarcinoma cell lines
    • Cerda S.R., Wilkinson IV J., and Broitman S.A. Regulation of cholesterol synthesis in four colonic adenocarcinoma cell lines. Lipid 30 (1995) 1083-1092
    • (1995) Lipid , vol.30 , pp. 1083-1092
    • Cerda, S.R.1    Wilkinson IV, J.2    Broitman, S.A.3
  • 40
    • 0026646896 scopus 로고
    • The effect of 25-hydroxycholesterol on the regulation of apolipoprotein E mRNA levels and secretion in the human hepatoma HepG2
    • Tam S.P., and Ramharack R. The effect of 25-hydroxycholesterol on the regulation of apolipoprotein E mRNA levels and secretion in the human hepatoma HepG2. Atherosclerosis 95 (1992) 137-146
    • (1992) Atherosclerosis , vol.95 , pp. 137-146
    • Tam, S.P.1    Ramharack, R.2
  • 42
    • 18144384743 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor delta and gamma agonists differentially alter tumor differentiation and progression during mammary carcinogenesis
    • Yin Y., Russell R.G., Dettin L.E., et al. Peroxisome proliferator-activated receptor delta and gamma agonists differentially alter tumor differentiation and progression during mammary carcinogenesis. Cancer Res 65 (2005) 3950-3957
    • (2005) Cancer Res , vol.65 , pp. 3950-3957
    • Yin, Y.1    Russell, R.G.2    Dettin, L.E.3
  • 43
    • 67349168710 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma overexpression and knockdown: impact on human B cell lymphoma proliferation and serviva
    • Garcia-Bates T.M., Peslak S.A., Baglole C.J., et al. Peroxisome proliferator-activated receptor gamma overexpression and knockdown: impact on human B cell lymphoma proliferation and serviva. Cancer Immunol Immunother 58 (2009) 1071-1083
    • (2009) Cancer Immunol Immunother , vol.58 , pp. 1071-1083
    • Garcia-Bates, T.M.1    Peslak, S.A.2    Baglole, C.J.3
  • 44
    • 0037959071 scopus 로고    scopus 로고
    • The state of lipid rafts: from model membrane to cells
    • Edidin M. The state of lipid rafts: from model membrane to cells. Ann Rev Biophys Biomol Struct 32 (2003) 257-283
    • (2003) Ann Rev Biophys Biomol Struct , vol.32 , pp. 257-283
    • Edidin, M.1
  • 45
    • 64549139703 scopus 로고    scopus 로고
    • Involvement of raft aggregates enriched in Fas/CD95 death-inducing signaling complex in the antileukemic action of edelfosine in Jurkat cells
    • Gajate C., Gonzalez-Camacho F., and Mollinedo F. Involvement of raft aggregates enriched in Fas/CD95 death-inducing signaling complex in the antileukemic action of edelfosine in Jurkat cells. PLoS One 4 (2009) e5044
    • (2009) PLoS One , vol.4
    • Gajate, C.1    Gonzalez-Camacho, F.2    Mollinedo, F.3


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