Cisplatin-induced apoptosis involves a Fas-ROCK-ezrin-dependent actin remodelling in human colon cancer cells

European Journal of Cancer

Volumn 46, Issue 8, 2010, Pages 1445-1455

  Rebillard, Amélie ^a   Jouan Lanhouet, Sandrine ^a   Jouan, Elodie ^a   Legembre, Patrick ^a   Pizon, Mathieu ^b   Sergent, Odile ^a   Gilot, David ^a   Tekpli, Xavier ^a   Lagadic Gossmann, Dominique ^a   Dimanche Boitrel, Marie Thérèse ^a  

^a UNIVERSITÉ DE RENNES 1   (France)

^b CNRS Bordeaux Segalen University   (France)

Author keywords

Actin cytoskeleton; Cisplatin; Colon cancer; Ezrin; Fas; Lipid rafts; Membrane fluidity; RhoA GTP; RNA interference; ROCK

Indexed keywords

ACTIN; CASPASE 3; CELL PROTEIN; CISPLATIN; EZRIN; FAS ANTIGEN; FAS ASSOCIATED DEATH DOMAIN PROTEIN; FLUORESCEIN ISOTHIOCYANATE; LATRUNCULIN A; PHALLOIDIN; PROCASPASE 8; PROTEIN ROCK; RHO KINASE; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; ACTIN KINASE; ANTINEOPLASTIC AGENT; CYTOSKELETON PROTEIN; FAS LIGAND; PROTEIN SERINE THREONINE KINASE;

ACTIN POLYMERIZATION; APOPTOSIS; ARTICLE; CANCER CELL; CANCER CELL CULTURE; CELL MEMBRANE; CELLULAR DISTRIBUTION; COLON CANCER; CONTROLLED STUDY; CYTOSKELETON; DRUG EXPOSURE; DRUG MECHANISM; ELECTRON SPIN RESONANCE; ENZYME ACTIVITY; FLUORESCENCE MICROSCOPY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; LIPID RAFT; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; RNA INTERFERENCE; STAINING; WESTERN BLOTTING; COLONIC NEOPLASMS; DRUG EFFECTS; METABOLISM; PATHOLOGY; PHYSIOLOGY; SIGNAL TRANSDUCTION; TUMOR CELL CULTURE;

ANTIGENS, CD95; ANTINEOPLASTIC AGENTS; APOPTOSIS; CISPLATIN; COLONIC NEOPLASMS; CYTOSKELETAL PROTEINS; FAS LIGAND PROTEIN; HUMANS; PROTEIN-SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED;

EID: 77951665350     PISSN: 09598049     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejca.2010.01.034     Document Type: Article

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