Functional characterisation of cell cycle-related kinase (CCRK) in colorectal cancer carcinogenesis

European Journal of Cancer

Volumn 46, Issue 9, 2010, Pages 1752-1761

  An, Xiaomeng ^a   Ng, Samuel S ^a   Xie, Dan ^b   Zeng, Yi Xin ^b   Sze, Johnny ^a   Wang, Jide ^a   Chen, Yang Chao ^c   Chow, Billy K C ^a   Lu, Gang ^c   Poon, Wai Sang ^c   Kung, Hsiang fu ^b,c   Wong, Benjamin C Y ^a   Lin, Marie Chia mi ^a,c  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

^b SUN YAT SEN UNIVERSITY CANCER CENTER   (China)

^c CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Carcinogenesis; CCRK; Cell cycle; Colorectal cancer

Indexed keywords

CELL CYCLE RELATED KINASE; CYCLIN DEPENDENT KINASE 2; CYCLIN E; PROTEIN KINASE; RETINOBLASTOMA PROTEIN; SERINE; SHORT HAIRPIN RNA; SMALL INTERFERING RNA; THREONINE; UNCLASSIFIED DRUG; CYCLIN DEPENDENT KINASE; CYCLIN-DEPENDENT KINASE-ACTIVATING KINASE; CYCLINE; TUMOR PROTEIN;

ADULT; AGED; ARTICLE; CANCER CELL; CANCER STAGING; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL GROWTH; CELL PROLIFERATION; COLON CARCINOGENESIS; COLORECTAL CANCER; CONTROLLED STUDY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; ENZYME REGULATION; FEMALE; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; CELL CYCLE; COLORECTAL NEOPLASMS; GENE SILENCING; IMMUNOHISTOCHEMISTRY; METABOLISM; MICROARRAY ANALYSIS; MIDDLE AGED; PHOSPHORYLATION; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR CELL LINE; VERY ELDERLY; WESTERN BLOTTING;

ADULT; AGED; AGED, 80 AND OVER; BLOTTING, WESTERN; CELL CYCLE; CELL LINE, TUMOR; COLORECTAL NEOPLASMS; CYCLIN-DEPENDENT KINASES; CYCLINS; FEMALE; GENE KNOCKDOWN TECHNIQUES; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MICROARRAY ANALYSIS; MIDDLE AGED; NEOPLASM PROTEINS; PHOSPHORYLATION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, SMALL INTERFERING; TRANSFECTION;

EID: 77952581052     PISSN: 09598049     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejca.2010.04.007     Document Type: Article

References (19)

1. Jemal A., Siegel R., Ward E., et al. Cancer statistics, 2009. CA Cancer J Clin 59 (2009) 225-249
2. Hong Kong Cancer Stat 2007. Hong Kong Cancer Registry: Hong Kong Hospital Authority; 2009.
3. Yuen S.T., Chung L.P., Leung S.Y., et al. Colorectal carcinoma in Hong Kong: epidemiology and genetic mutations. Br J Cancer 76 (1997) 1610-1616
4. Liu Y., Wu C., and Galaktionov K. p42, a novel cyclin-dependent kinase-activating kinase in mammalian cells. J Biol Chem 279 (2004) 4507-4514
5. Wohlbold L., Larochelle S., Liao J.C., et al. The cyclin-dependent kinase (CDK) family member PNQALRE/CCRK supports cell proliferation but has no intrinsic CDK-activating kinase (CAK) activity. Cell Cycle 5 (2006) 546-554
6. Fu Z., Larson K.A., Chitta R.K., et al. Identification of yin-yang regulators and a phosphorylation consensus for male germ cell-associated kinase (MAK)-related kinase. Mol Cell Biol 26 (2006) 8639-8654
7. Ng S.S., Cheung Y.T., An X.M., et al. Cell cycle-related kinase: a novel candidate oncogene in human glioblastoma. J Natl Cancer Inst 99 (2007) 936-948
8. Wu G.Q., Xie D., Yang G.F., et al. Cell cycle-related kinase supports ovarian carcinoma cell proliferation via regulation of cyclin D1 and is a predictor of outcome in patients with ovarian carcinoma. Int J Cancer 125 (2009) 2631-2642
9. Xie D., Sham J.S., Zeng W.F., et al. Heterogeneous expression and association of beta-catenin, p16 and c-myc in multistage colorectal tumorigenesis and progression detected by tissue microarray. Int J Cancer 107 (2003) 896-902
10. Xie D., Lau S.H., Sham J.S., et al. Up-regulated expression of cytoplasmic clusterin in human ovarian carcinoma. Cancer 103 (2005) 277-283
11. Roninson I.B., Broude E.V., and Chang B.D. If not apoptosis, then what? Treatment-induced senescence and mitotic catastrophe in tumor cells. Drug Resist Updat 4 (2001) 303-313
12. Bracey T.S., Williams A.C., and Paraskeva C. Inhibition of radiation-induced G2 delay potentiates cell death by apoptosis and/or the induction of giant cells in colorectal tumor cells with disrupted p53 function. Clin Cancer Res 3 (1997) 1371-1381
13. Pines J. Four-dimensional control of the cell cycle. Nat Cell Biol 1 (1999) E73-79
14. Furuno N., den Elzen N., and Pines J. Human cyclin A is required for mitosis until mid prophase. J Cell Biol 147 (1999) 295-306
15. Juan G., and Cordon-Cardo C. Intranuclear compartmentalization of cyclin E during the cell cycle: disruption of the nucleoplasm-nucleolar shuttling of cyclin E in bladder cancer. Cancer Res 61 (2001) 1220-1226
16. Ohi R., and Gould K.L. Regulating the onset of mitosis. Curr Opin Cell Biol 11 (1999) 267-273
17. Reed S.I. Control of the G1/S transition. Cancer Surv 29 (1997) 7-23
18. Cobrinik D. Pocket proteins and cell cycle control. Oncogene 24 (2005) 2796-2809
19. Meraldi P., Lukas J., Fry A.M., et al. Centrosome duplication in mammalian somatic cells requires E2F and Cdk2-cyclin A. Nat Cell Biol 1 (1999) 88-93