Scalable total syntheses of N -linked tryptamine dimers by direct indole-aniline coupling: Psychotrimine and kapakahines B and F

Journal of the American Chemical Society

Volumn 132, Issue 20, 2010, Pages 7119-7137

  Newhouse, Timothy ^a   Lewis, Chad A ^a   Eastman, Kyle J ^a   Baran, Phil S ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DIASTEREOSELECTIVITIES; ELECTROPHILIC ATTACK; GRAM SCALE; N-LINKED; QUATERNIZATION; TOTAL SYNTHESIS; TRYPTAMINES;

OLIGOMERS;

ANILINE;

ANILINE; ANTINEOPLASTIC AGENT; ASPERAZINE; CATION; CHETOMIN; CHIMONANTHINE; COMMUNESIN F; DIMER; HIMASTATIN; INDOLE ALKALOID; KAPAKAHINE B; KAPAKAHINE F; PEROPHORAMIDINE; PHYTIC ACID CALCIUM MAGNESIUM SALT; PSYCHOTETRAMINE; PSYCHOTRIMINE; QUADRIGEMINE C; TRYPTAMINE; UNCLASSIFIED DRUG; VINBLASTINE;

AMINO ACID ANALYSIS; AMINO TERMINAL SEQUENCE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CHEMICAL MODIFICATION; CHEMICAL REACTION; DRUG STRUCTURE; DRUG SYNTHESIS; MOLECULAR MECHANICS; STEREOCHEMISTRY;

ANILINE COMPOUNDS; CELL LINE, TUMOR; DIMERIZATION; HUMANS; INDOLE ALKALOIDS; INDOLES; INHIBITORY CONCENTRATION 50; NITROGEN; OXIDATION-REDUCTION; PEPTIDES, CYCLIC; STEREOISOMERISM; SUBSTRATE SPECIFICITY; TRYPTAMINES;

EID: 77952559330     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja1009458     Document Type: Article

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