OX40 induces CCL20 expression in the context of antigen stimulation: An expanding role of co-stimulatory molecules in chemotaxis

Cytokine

Volumn 50, Issue 3, 2010, Pages 253-259

  Zhong, Wenwei ^a,b   Zhang, Zili ^b   Hinrichs, David ^c   Wu, Xiumei ^b   Hall, Mark ^b   Xia, Zhenwei ^a   Rosenbaum, James T ^d  

^a SHANGHAI SECOND MEDICAL UNIVERSITY   (China)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^c PORTLAND VA MEDICAL CENTER   (United States)

^d OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

CCL20; CD4+ T cells; Co stimulatory molecule; OX40; T cell co stimulation

Indexed keywords

CD134 ANTIGEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MACROPHAGE INFLAMMATORY PROTEIN 3ALPHA; OVALBUMIN; PHOSPHATIDYLINOSITOL 3 KINASE; STRESS ACTIVATED PROTEIN KINASE INHIBITOR; T LYMPHOCYTE RECEPTOR;

ADAPTIVE IMMUNITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIGEN EXPRESSION; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL INFILTRATION; CELL MIGRATION; CHEMOTAXIS; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOSE RESPONSE; FEMALE; HISTOPATHOLOGY; IMMUNOSTIMULATION; LYMPHOCYTE ACTIVATION; MOUSE; NONHUMAN; PNEUMONIA; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SPLEEN; SPLEEN CELL; UPREGULATION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ADMINISTRATION, INTRANASAL; ANIMALS; ANTIBODIES; ANTIGENS; CD4-POSITIVE T-LYMPHOCYTES; CELL EXTRACTS; CHEMOKINE CCL20; CHEMOTAXIS; FEMALE; INFLAMMATION; INHALATION EXPOSURE; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LUNG; MICE; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; NEUTRALIZATION TESTS; NF-KAPPA B; OVALBUMIN; PROTEIN KINASE INHIBITORS; RECEPTORS, OX40; UP-REGULATION;

MUS;

EID: 77952553943     PISSN: 10434666     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cyto.2010.03.021     Document Type: Article

References (47)

1. Mosmann T.R., Li L., Hengartner H., Kagi D., Fu W., Sad S. Differentiation and functions of T cell subsets. Ciba Found Sym 1997, 204:148-154.
2. Lanzavecchia A., Sallusto F. Antigen decoding by T lymphocytes: from synapses to fate determination. Nat Immunol 2001, 2(6):487-492.
3. Louten J., Boniface K., de Waal Malefyt R. Development and function of TH17 cells in health and disease. J Allergy Clin Immunol 2009, 123(5):1004-1011.
4. Ahern P.P., Izcue A., Maloy K.J., Powrie F. The interleukin-23 axis in intestinal inflammation. Immunol Rev 2008, 226:147-159.
5. Tesmer L.A., Lundy S.K., Sarkar S., Fox D.A. Th17 cells in human disease. Immunol Rev 2008, 223:87-113.
6. Caspi R. Autoimmunity in the immune privileged eye: pathogenic and regulatory T cells. Immunol Res 2008, 42(1-3):41-50.
7. Podojil J.R., Miller S.D. Molecular mechanisms of T-cell receptor and costimulatory molecule ligation/blockade in autoimmune disease therapy. Immunol Rev 2009, 229:337-355.
8. Goronzy J.J., Weyand C.M. T-cell co-stimulatory pathways in autoimmunity. Arthritis Res Ther 2008, 10(Suppl. 1):S3.
9. Alegre M.L., Frauwirth K.A., Thompson C.B. T-cell regulation by CD28 and CTLA-4. Nat Rev Immunol 2001, 1:220-228.
10. Coyle A.J., Gutierrez-Ramos J.C. The expanding B7 superfamily: increasing complexity in costimulatory signals regulating T cell function. Nat Immunol 2001, 2:203-209.
11. Mueller D.L. T cells: a proliferation of costimulatory molecules. Curr Biol 2000, 10:R227-R230.
12. Marelli-Berg F.M., Cannella L., Dazzi F., Mirenda V. The highway code of T cell trafficking. J Pathol 2008, 214(2):179-189.
13. David R., Marelli-Berg F.M. Regulation of T-cell migration by co-stimulatory molecules. Biochem Soc Trans 2007, 5(Pt 5):1114-1118.
14. Marelli-Berg F.M., Okkenhaug K., Mirenda V. A two-signal model for T cell trafficking. Trends Immunol 2007, 28(6):267-273.
15. Mirenda V., Jarmin S.J., David R., Dyson J., Scott D., Gu Y., et al. Physiologic and aberrant regulation of memory T-cell trafficking by the costimulatory molecule CD28. Blood 2007, 109(7):2968-2977.
16. Ward S.G., Marelli-Berg F.M. Mechanisms of chemokine and antigen-dependent T-lymphocyte navigation. Biochem J 2009, 418(1):13-27.
17. Croft M. The role of TNF superfamily members in T-cell function and diseases. Nat Rev Immunol 2009, 9:271-285.
18. Croft M., So T., Duan W., Soroosh P. The significance of OX40 and OX40L to T-cell biology and immune disease. Immunol Rev 2009, 229:173-191.
19. Weinberg A.D., Wegmann K.W., Funatake C., Whitham R.H. Blocking OX-40/OX-40 ligand interaction in vitro and in vivo leads to decreased T cell function and amelioration of experimental allergic encephalomyelitis. J Immunol 1999, 162:1818-1826.
20. Flynn S., Toellner K.M., Raykundalia C., Goodall M., Lane P. CD4 T cell cytokine differentiation: the B cell activation molecule, OX40 ligand, instructs CD4 T cells to express IL-4 and upregulates expression of the chemokine receptor blr-1. J Exp Med 1998, 188:297-304.
21. Lane P. Role of OX40 signals in coordinating CD4 T cell selection, migration, and cytokine differentiation in T helper (Th)1 and Th2 cells. J Exp Med 2000, 191(2):201-206.
22. Varona R., Zaballos A., Gutiérrez J., Martín P., Roncal F., Albar J.P., et al. Molecular cloning, functional characterization and mRNA expression analysis of the murine chemokine receptor CCR6 and its specific ligand MIP-3 α. FEBS Lett 1998, 440:188-194.
23. Tanaka Y., Imai T., Baba M., Ishikawa I., Uehira M., Nomiyama H., et al. Selective expression of liver and activation-regulated chemokine (LARC) in intestinal epithelium in mice and humans. Eur J Immunol 1999, 29:633-642.
24. Schutyser E., Struyf S., Menten P., Lenaerts J.P., Conings R., Put W., et al. Regulated production and molecular diversity of human liver and activation-regulated chemokine/macrophage inflammatory protein-3α from normal and transformed cells. J Immunol 2000, 165:4470-4477.
25. Hirota K., Yoshitomi H., Hashimoto M., Maeda S., Teradaira S., Sugimoto N., et al. Preferential recruitment of CCR6-expressing Th17 cells to inflamed joints via CCL20 in rheumatoid arthritis and its animal model. J Exp Med 2007, 204(12):2803-2812.
26. Wilson N.J., Boniface K., Chan J.R., McKenzie B.S., Blumenschein W.M., Mattson J.D., et al. Development, cytokine profile and function of human interleukin 17-producing helper T cells. Nat Immunol 2007, 8(9):950-957.
27. Yamazaki T., Yang X.O., Chung Y., Fukunaga A., Nurieva R., Pappu B., et al. CCR6 regulates the migration of inflammatory and regulatory T cells. J Immunol 2008, 181(12):8391-8401.
28. Schutyser E., Struyf S., Van Damme J. The CC chemokine CCL20 and its receptor CCR6. Cytokine Growth Factor Rev 2003, 14(5):409-426.
29. Zhang Z., Zhong W., Spencer D., Chen H., Lu H., Kawaguchi T., et al. Interleukin-17 causes neutrophil mediated inflammation in ovalbumin-induced uveitis in DO11.10 mice. Cytokine 2009, 46(1):79-91.
30. Marks B.R., Nowyhed H.N., Choi J.Y., Poholek A.C., Odegard J.M., Flavell R.A., et al. Thymic self-reactivity selects natural interleukin 17-producing T cells that can regulate peripheral inflammation. Nat Immunol 2009, 10(10):1125-1132.
31. Kao C.Y., Huang F., Chen Y., Thai P., Wachi S., Kim C., et al. Up-regulation of CC chemokine ligand 20 expression in human airway epithelium by IL-17 through a JAK-independent but MEK/NF-kappaB-dependent signaling pathway. J Immunol 2005, 175(10):6676-6685.
32. Kanda N., Shibata S., Tada Y., Nashiro K., Tamaki K., Watanabe S. Prolactin enhances basal and IL-17-induced CCL20 production by human keratinocytes. Eur J Immunol 2009, 39(4):996-1006.
33. Zhang Z., Zhong W., Hall M.J., Kurre P., Spencer D., Skinner A., et al. CXCR4 but not CXCR7 is mainly implicated in ocular leukocyte trafficking during ovalbumin-induced acute uveitis. Exp Eye Res 2009, 89(4):522-531.
34. Olszyna D.P., De Jonge E., Dekkers P.E., van Deventer S.J., van der Poll T. Induction of cell-associated chemokines after endotoxin administration to healthy humans. Infect Immun 2001, 69(4):2736-2738.
35. Marie C., Fitting C., Cheval C., Losser M.R., Carlet J., Payen D., et al. Presence of high levels of leukocyte-associated interleukin-8 upon cell activation and in patients with sepsis syndrome. Infect Immun 1997, 65(3):865-881.
36. Dembinski J., Behrendt D., Heep A., Dorn C., Reinsberg J., Bartmann P. Cell-associated interleukin-8 in cord blood of term and preterm infants. Clin Diagn Lab Immunol 2002, 9(2):320-323.
37. Hieshima K., Nagira M., Imai T., Kusuda J., Ridanpää M., Takagi S., et al. Molecular cloning of a novel human CC chemokine secondary lymphoid-tissue chemokine that is a potent chemoattractant for lymphocytes and mapped to chromosome 9p13. J Biol Chem 1997, 272(31):19518-19524.
38. Rossi D.L., Vicari A.P., Franz-Bacon K., McClanahan T.K., Zlotnik A. Identification through bioinformatics of two new macrophage proinflammatory human chemokines: MIP-3alpha and MIP-3beta. J Immunol 1997, 158(3):1033-1036.
39. Siddiqui R.A., Akard L.P., Garcia J.G., Cui Y., English D. Chemotactic migration triggers IL-8 generation in neutrophilic leukocytes. J Immunol 1999, 162(2):1077-1083.
40. Ethuin F., Delarche C., Benslama S., Gougerot-Pocidalo M.A., Jacob L., Chollet-Martin S. Interleukin-12 increases interleukin 8 production and release by human polymorphonuclear neutrophils. J Leukoc Biol 2001, 70(3):439-446.
41. Salek-Ardakani S., Croft M. Regulation of CD4 T cell memory by OX40 (CD134). Vaccine 2006, 24:872-883.
42. Salek-Ardakani S., Song J., Halteman B.S., Jember A.G., Akiba H., Yagita H., et al. OX40 (CD134) controls memory T helper 2 cells that drive lung inflammation. J Exp Med 2003, 198(2):315-324.
43. Sugita S., Kohno T., Yamamoto K., Imaizumi Y., Nakajima H., Ishimaru T., et al. Induction of macrophage-inflammatory protein-3alpha gene expression by TNF-dependent NF-kappaB activation. J Immunol 2002, 168(11):5621-5628.
44. Battaglia F., Delfino S., Merello E., Puppo M., Piva R., Varesio L., et al. Hypoxia transcriptionally induces macrophage-inflammatory protein-3alpha/CCL-20 in primary human mononuclear phagocytes through nuclear factor (NF)-kappaB. J Leukoc Biol 2008, 83(3):648-662.
45. Sirard J.C., Didierlaurent A., Cayet D., Sierro F., Rumbo M. Toll-like receptor 5- and lymphotoxin beta receptor-dependent epithelial Ccl20 expression involves the same NF-kappaB binding site but distinct NF-kappaB pathways and dynamics. Biochim Biophys Acta 2009, 1789(5):386-394.
46. Okkenhaug K., Vanhaesebroeck B. PI3K in lymphocyte development, differentiation and activation. Nat Rev Immunol 2003, 3(4):317-330.
47. Fruman D.A., Bismuth G. Fine tuning the immune response with PI3K. Immunol Rev 2009, 228(1):253-272.