The role of organic anion transporting polypeptides (OATPs/SLCOs) in the toxicity of different microcystin congeners in vitro: A comparison of primary human hepatocytes and OATP-transfected HEK293 cells

Toxicology and Applied Pharmacology

Volumn 245, Issue 1, 2010, Pages 9-20

  Fischer, A ^a   Hoeger, S J ^a   Stemmer, K ^a   Feurstein, D J ^a   Knobeloch, D ^b   Nussler, A ^c   Dietrich, D R ^a  

^a UNIVERSITY OF KONSTANZ   (Germany)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^c TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

Cyanobacteria; Microcystin; OATP

Indexed keywords

BROMSULFOPHTHALEIN; MICROCYSTIN; ORGANIC ANION TRANSPORTER; ORGANIC ANION TRANSPORTER 1; ORGANIC ANION TRANSPORTER 3; PHOSPHOPROTEIN PHOSPHATASE; RECOMBINANT PROTEIN; TAUROCHOLIC ACID;

ARTICLE; CELL STRAIN HEK293; CONTROLLED STUDY; CYANOBACTERIUM; CYTOTOXICITY; EXPRESSION VECTOR; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IN VITRO STUDY; INTOXICATION; LIVER CELL; LIVER INJURY; PROTEIN EXPRESSION; RISK ASSESSMENT;

CARCINOGENS; CELL LINE; HARMFUL ALGAL BLOOM; HEPATOCYTES; HUMANS; KIDNEY; MICROCYSTINS; ORGANIC ANION TRANSPORTERS; PEPTIDES; TOXICITY TESTS; TRANSFECTION;

CYANOBACTERIA;

EID: 77952549883     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2010.02.006     Document Type: Article

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