Proteases and sFlt-1 Release in the Human Placenta

Placenta

Volumn 31, Issue 6, 2010, Pages 512-518

  Zhao, S ^a   Gu, Y ^a   Fan, R ^a   Groome, L J ^a   Cooper, D ^a   Wang, Y ^a  

^a Louisiana State University School of Medicine Shreveport   (United States)

Author keywords

Placenta; Preeclampsia; Protease; sFlt 1

Indexed keywords

ADAM10 ENDOPEPTIDASE; BENZYLSULFONYL FLUORIDE; CHYMASE; CHYMOTRYPSIN; CYSTEINE PROTEINASE INHIBITOR; METALLOPROTEINASE; METALLOPROTEINASE INHIBITOR; N [N (3 CARBOXYOXIRANE 2 CARBONYL)LEUCYL]AGMATINE; PHENANTHROLINE; PROTEINASE; PROTEINASE INHIBITOR; SERINE PROTEINASE INHIBITOR; VASCULOTROPIN RECEPTOR 1;

ARTICLE; CONTROLLED STUDY; CULTURE MEDIUM; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; PLACENTA; PLACENTA VILLUS; PRIORITY JOURNAL; PROTEIN SECRETION; SYNCYTIOTROPHOBLAST;

ANALYSIS OF VARIANCE; BLOTTING, WESTERN; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; PEPTIDE HYDROLASES; PLACENTA; PRE-ECLAMPSIA; PREGNANCY; PROTEASE INHIBITORS; TISSUE CULTURE TECHNIQUES; TROPHOBLASTS; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-1;

EID: 77952546033     PISSN: 01434004     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.placenta.2010.03.014     Document Type: Article

References (40)

1. Maynard S.E., Min J.Y., Merchan J., Lim K.H., Li J., Mondal S., et al. Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia. J Clin Invest 111 5 (2003) 649-658
2. Gu Y., Lewis D.F., and Wang Y. Placental productions and expressions of soluble endoglin, soluble fms-like tyrosine kinase receptor-1, and placental growth factor in normal and preeclamptic pregnancies. J Clin Endocrinol Metab 93 1 (2008) 260-266
3. Mutter W.P., and Karumanchi S.A. Molecular mechanisms of preeclampsia. Microvasc Res 75 1 (2008) 1-8
4. He Y., Smith S.K., Day K.A., Clark D.E., Licence D.R., and Charnock-Jones D.S. Alternative splicing of vascular endothelial growth factor (VEGF)-R1 (FLT-1) pre-mRNA is important for the regulation of VEGF activity. Mol Endocrinol 13 4 (1999) 537-545
5. Thomas C.P., Andrews J.I., and Liu K.Z. Intronic polyadenylation signal sequences and alternate splicing generate human soluble Flt1 variants and regulate the abundance of soluble Flt1 in the placenta. FASEB J 21 14 (2007) 3885-3895
6. Rose-John S., and Heinrich P.C. Soluble receptors for cytokines and growth factors: generation and biological function. Biochem J 200 Pt 2 (1994) 281-290
7. Tedder T.F. Cell-surface receptor shedding: a means of regulating function. Am J Respir Cell Mol Biol 5 4 (1991) 305-306
8. Hooper N.M., Karran E.H., and Turner A.J. Membrane protein secretases. Biochem J 321 Pt 2 (1997) 265-279
9. Oppong S.Y., and Hooper N.M. Characterization of a secretase activity which releases angiotensin-converting enzyme from the membrane. Biochem J 292 Pt 2 (1993) 597-603
10. Cohen M., Meisser A., and Bischof P. Metalloproteinases and human placental invasiveness. Placenta 27 8 (2006) 783-793
11. Huppertz B., Bartz C., and Kokozidou M. Trophoblast fusion: fusogenic proteins, syncytins and ADAMs, and other prerequisites for syncytial fusion. Micron 37 6 (2006) 509-517
12. Mason R.W. Emerging functions of placental cathepsins. Placenta 29 5 (2008) 385-390
13. Levy R., and Nelson D.M. To be, or not to be, that is the question. Apoptosis in human trophoblast. Placenta 21 1 (2000) 1-13
14. Wang Y., Gu Y., Zhang Y., Lewis D.F., Alexander J.S., and Granger D.N. Increased chymotrypsin-like protease (chymase) expression and activity in placentas from women with preeclampsia. Placenta 28 (2007) 263-269
15. Wang Y, Gu Y, Lewis DF, Alexander JS, Granger DN. Elevated plasma chymotrypsin-like protease (chymase) activity in women with preeclampsia. Hypertens Pregn, in press.
16. Wang Y., Zhang Y., Lewis D.F., Gu Y., Li H., Granger D.N., et al. Protease chymotrypsin mediates the endothelial expression of P- and E-selectin, but not ICAM and VCAM, induced by placental trophoblasts from preeclamptic pregnancies. Placenta 24 (2003) 851-861
17. Achmad T.H., Winterscheidt A., Lindemann C., and Rao G.S. Oxidized low density lipoprotein acts on endothelial cells in culture to enhance endothelin secretion and monocyte migration. Methods Find Exp Clin Pharmacol 19 3 (1997) 153-159
18. Rofstad E.K., Mathiesen B., Kindem K., and Galappathi K. Acidic extracellular pH promotes experimental metastasis of human melanoma cells in athymic nude mice. Cancer Res 66 13 (2006) 6699-6707
19. Vlata Z., Porichis F., Tzanakakis G., Tsatsakis A., and Krambovitis E. A study of zearalenone cytotoxicity on human peripheral blood mononuclear cells. Toxicol Lett 165 3 (2006) 274-281
20. Zhao S., Gu Y., Lewis D.F., and Wang Y. Predominant basal directional release of thromboxane, but not prostacyclin, by placental trophoblasts from normal and preeclamptic pregnancies. Placenta 29 1 (2008) 81-88
21. Guzeloglu-Kayisli O., Kayisli U.A., Al-Rejjal R., Zheng W., Luleci G., and Arici A. Regulation of PTEN (phosphatase and tensin homolog deleted on chromosome 10) expression by estradiol and progesterone in human endometrium. J Clin Endocrinol Metab 88 10 (2003) 5017-5026
22. Lockwood C.J., Yen C.F., Basar M., Kayisli U.A., Martel M., Buhimschi I., et al. Preeclampsia-related inflammatory cytokines regulate interleukin-6 expression in human decidual cells. Am J Pathol 172 6 (2008) 1571-1579
23. McCulloch D.R., Akl P., Samaratunga H., Herington A.C., and Odorico D.M. Expression of the disintegrin metalloprotease, ADAM-10, in prostate cancer and its regulation by dihydrotestosterone, insulin-like growth factor I, and epidermal growth factor in the prostate cancer cell model LNCaP. Clin Cancer Res 10 1 (2004) 314-323
24. Levine R.J., Maynard S.E., Qian C., Lim K.H., England L.J., Yu K.F., et al. Circulating angiogenic factors and the risk of preeclampsia. N Engl J Med 350 7 (2004) 672-683
25. Stonelake P.S., Jones C.E., Neoptolemos J.P., and Baker P.R. Proteinase inhibitors reduce basement membrane degradation by human breast cancer cell lines. Br J Cancer 75 7 (1997) 951-957
26. Ebihara N., Funaki T., Murakami A., Takai S., and Miyazaki M. Mast cell chymase decreases the barrier function and inhibits the migration of corneal epithelial cells. Curr Eye Res 30 12 (2005) 1061-1069
27. Smalley D.M., and Ley K. l-selectin: mechanisms and physiological significance of ectodomain cleavage. J Cell Mol Med 9 2 (2005) 255-266
28. Lee M.C., Alpaugh M.L., Nguyen M., Deato M., Dishakjian L., and Barsky S.H. Myoepithelial-specific CD44 shedding is mediated by a putative chymotrypsin-like sheddase. Biochem Biophys Res Commun 279 1 (2000) 116-123
29. Alpaugh M.L., Lee M.C., Nguyen M., Deato M., Dishakjian L., and Barsky S.H. Myoepithelial-specific CD44 shedding contributes to the anti-invasive and antiangiogenic phenotype of myoepithelial cells. Exp Cell Res 261 1 (2000) 150-158
30. Wang H.X., Zhao Y.G., Wang H.M., Yang Q., Lin H.Y., Sang Q.X., et al. Expression of adamalysin 19/ADAM19 in the endometrium and placenta of rhesus monkey (Macaca mulatta) during early pregnancy. Mol Hum Reprod 11 6 (2005) 429-535
31. Zhao M., Qiu W., Li Y., Sang Q.A., and Wang Y. Dynamic change of Adamalysin 19 (ADAM19) in human placentas and its effects on cell invasion and adhesion in human trophoblastic cells. Sci China, C, Life Sci 52 8 (2009) 710-718
32. Gack S., Marmé A., Marmé F., Wrobel G., Vonderstrass B., Bastert G., et al. Preeclampsia: increased expression of soluble ADAM 12. J Mol Med 83 11 (2005) 887-896
33. Leach R.E., Romero R., Kim Y.M., Chaiworapongsa T., Kilburn B., Das S.K., et al. Pre-eclampsia and expression of heparin-binding EGF-like growth factor. Lancet 360 9341 (2002) 1215-1219
34. Asakura M., Kitakaze M., Takashima S., Liao Y., Ishikura F., Yoshinaka T., et al. Cardiac hypertrophy is inhibited by antagonism of ADAM12 processing of HB-EGF: metalloproteinase inhibitors as a new therapy. Nat Med 8 1 (2002) 35-40
35. Anderegg U., Eichenberg T., Parthaune T., Haiduk C., Saalbach A., Milkova L., et al. ADAM10 is the constitutive functional sheddase of CD44 in human melanoma cells. J Invest Dermatol 129 6 (2009) 1471-1482
36. Scholz F., Schulte A., Adamski F., Hundhausen C., Mittag J., Schwarz A., et al. Constitutive expression and regulated release of the transmembrane chemokine CXCL16 in human and murine skin. J Invest Dermatol 127 6 (2007) 1444-1455
37. Hakulinen J., and Keski-Oja J. ADAM10-mediated release of complement membrane cofactor protein during apoptosis of epithelial cells. J Biol Chem 281 30 (2006) 21369-21376
38. Reiss K., Maretzky T., Ludwig A., Tousseyn T., de Strooper B., Hartmann D., et al. ADAM10 cleavage of N-cadherin and regulation of cell-cell adhesion and beta-catenin nuclear signalling. EMBO J 24 4 (2005) 742-752
39. Maretzky T., Reiss K., Ludwig A., Buchholz J., Scholz F., Proksch E., et al. ADAM10 mediates E-cadherin shedding and regulates epithelial cell-cell adhesion, migration, and beta-catenin translocation. Proc Natl Acad Sci U S A 102 26 (2005) 9182-9187
40. Sung S.Y., Kubo H., Shigemura K., Arnold R.S., Logani S., Wang R., et al. Oxidative stress induces ADAM9 protein expression in human prostate cancer cells. Cancer Res 66 19 (2006) 9519-9526