Preeclampsia: Increased expression of soluble ADAM 12

Journal of Molecular Medicine

Volumn 83, Issue 11, 2005, Pages 887-896

  Gack, Sabine ^a   Marmé, Alexander ^b   Marmé, Frederik ^b   Wrobel, Gunnar ^a   Vonderstraß, Birgitta ^a   Bastert, Gunther ^b   Lichter, Peter ^a   Angel, Peter ^a   Schorpp Kistner, Marina ^a  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^b UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

Author keywords

ADAM 12 S; Meltrin ; Microarray; Placenta; Preeclampsia

Indexed keywords

A DISINTEGRIN AND METALLOPROTEINASE 2; BIOLOGICAL MARKER; COMPLEMENTARY DNA; METALLOPROTEINASE; PLASMA PROTEIN; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CLINICAL ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; DNA MICROARRAY; FEMALE; GENE EXPRESSION PROFILING; GESTATION PERIOD; HUMAN; HUMAN TISSUE; IN SITU HYBRIDIZATION; NUCLEOTIDE SEQUENCE; PLACENTA; PREECLAMPSIA; PREGNANT WOMAN; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; TISSUE SECTION; UNINDEXED SEQUENCE; UPREGULATION;

EID: 27744496570     PISSN: 09462716     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00109-005-0714-9     Document Type: Article

References (41)

1. Lala PK, Chakraborty C (2003) Factors regulating trophoblast migration and invasiveness: possible derangements contributing to pre-eclampsia and fetal injury. Placenta 24:575-587
2. Lachmeijer AM, Dekker GA, Pals G, Aarnoudse JG, ten Kate LP, Arngrimsson R (2002) Searching for preeclampsia genes: the current position. Eur J Obstet Gynecol Reprod Biol 105:94-113
3. Luft FC (2000) The preeclampsia enigma and the renin-angiotensin system. J Mol Med 78:63-65
4. Luft FC (2003) Pieces of the preeclampsia puzzle. Nephrol Dial Transplant 18:2209-2210
5. Lipstein H, Lee CC, Crupi RS (2003) A current concept of eclampsia. Am J Emerg Med 21:223-226
6. Bilban M, Head S, Desoye G, Quaranta V (2000) DNA microarrays: a novel approach to investigate genomics in trophoblast invasion - a review. Placenta 21(Suppl A):S99-S105
7. Cross JC (2003) The genetics of pre-eclampsia: a feto-placental or maternal problem? Clin Genet 64:96-103
8. Dekker GA, Robillard PY (2005) Preeclampsia: a couple's disease with maternal and fetal manifestations. Curr Pharm Des 11:699-710
9. Le Bouteiller P, Solier C, Proll J, Aguerre-Girr M, Fournel S, Lenfant F (1999) Placental HLA-G protein expression in vivo: where and what for? Hum Reprod Update 5:223-233
10. Pearson H (2002) Reproductive immunology: immunity's pregnant pause. Nature 420:265-266
11. Page NM, Woods RJ, Gardiner SM, Lomthaisong K, Gladwell RT, Butlin DJ, Manyonda IT, Lowry PJ (2000) Excessive placental secretion of neurokinin B during the third trimester causes pre-eclampsia. Nature 405:797-800
12. Krauss T, Emons G, Kuhn W, Augustin HG (2002) Predictive value of routine circulating soluble endothelial cell adhesion molecule measurements during pregnancy. Clin Chem 48:1418-1425
13. Krauss T, Pauer HU, Augustin HG (2004) Prospective analysis of placenta growth factor (PlGF) concentrations in the plasma of women with normal pregnancy and pregnancies complicated by preeclampsia. Hypertens Pregnancy 23:101-111
14. Maynard SE, Venkatesha S, Thadhani R, Karumanchi SA (2005) Soluble Fms-like tyrosine kinase 1 and endothelial dysfunction in the pathogenesis of preeclampsia. Pediatr Res 57:1R-7R
15. Dechend R, Muller DN, Wallukat G, Homuth V, Krause M, Dudenhausen J, Luft FC (2005) Activating auto-antibodies against the AT1 receptor in preeclampsia. Autoimmun Rev 4:61-65
16. Dechend R, Gratze P, Wallukat G, Shagdarsuren E, Plehm R, Brasen JH, Fiebeler A, Schneider W, Caluwaerts S, Vercruysse L, Pijnenborg R, Luft FC, Muller DN (2005) Agonistic autoantibodies to the AT1 receptor in a transgenic rat model of preeclampsia. Hypertension 45:742-746
17. Goldman-Wohl D, Yagel S (2002) Regulation of trophoblast invasion: from normal implantation to pre-eclampsia. Mol Cell Endocrinol 187:233-238
18. Fritz B, Schubert F, Wrobel G, Schwaenen C, Wessendorf S, Nessling M, Korz C, Rieker RJ, Montgomery K, Kucherlapati R, Mechtersheimer G, Eils R, Joos S, Lichter P (2002) Microarray-based copy number and expression profiling in dedifferentiated and pleomorphic liposarcoma. Cancer Res 62:2993-2998
19. Wrobel G, Schlingemann J, Hummerich L, Kramer H, Lichter P, Hahn M (2003) Optimization of high-density cDNA-microarray protocols by 'design of experiments'. Nucleic Acids Res 31:e67
20. Huber W, von Heydebreck A, Sultmann H, Poustka A, Vingron M (2002) Variance stabilization applied to microarray data calibration and to the quantification of differential expression. Bioinformatics 18(Suppl 1):S96-S104
21. Schorpp-Kistner M, Wang ZQ, Angel P, Wagner EF (1999) JunB is essential for mammalian placentation. EMBO J 18:934-948
22. Loechel F, Fox JW, Murphy G, Albrechtsen R, Wewer UM (2000) ADAM 12-S cleaves IGFBP-3 and IGFBP-5 and is inhibited by TIMP-3. Biochem Biophys Res Commun 278:511-515
23. Shi Z, Xu W, Loechel F, Wewer UM, Murphy LJ (2000) ADAM 12, a disintegrin metalloprotease, interacts with insulin-like growth factor-binding protein-3. J Biol Chem 275:18574-18580
24. Laigaard J, Sorensen T, Frohlich C, Pedersen BN, Christiansen M, Schiott K, Uldbjerg N, Albrechtsen R, Clausen HV, Ottesen B, Wewer UM (2003) ADAM12: a novel first-trimester maternal serum marker for Down syndrome. Prenat Diagn 23:1086-1091
25. Laigaard J, Christiansen M, Frohlich C, Pedersen BN, Ottesen B, Wewer UM (2005) The level of ADAM12-S in maternal serum is an early first-trimester marker of fetal trisomy 18. Prenat Diagn 25:45-46
26. Gilpin BJ, Loechel F, Mattei MG, Engvall E, Albrechtsen R, Wewer UM (1998) A novel, secreted form of human ADAM 12 (meltrin alpha) provokes myogenesis in vivo. J Biol Chem 273:157-166
27. Aronow BJ, Richardson BD, Handwerger S (2001) Microarray analysis of trophoblast differentiation: gene expression reprogramming in key gene function categories. Physiol Genomics 6:105-116
28. Tsoi SC, Cale JM, Bird IM, Kay HH (2003) cDNA microarray analysis of gene expression profiles in human placenta: up-regulation of the transcript encoding muscle subunit of glycogen phosphorylase in preeclampsia. J Soc Gynecol Investig 10:496-502
29. Pang ZJ, Xing FQ (2003) Comparative study on the expression of cytokine-receptor genes in normal and preeclamptic human placentas using DNA microarrays. J Perinat Med 31:153-162
30. Reimer T, Koczan D, Gerber B, Richter D, Thiesen HJ, Friese K (2002) Microarray analysis of differentially expressed genes in placental tissue of pre-eclampsia: up-regulation of obesity-related genes. Mol Hum Reprod 8:674-680
31. Pugh CW, Ratcliffe PJ (2003) Regulation of angiogenesis by hypoxia: role of the HIF system. Nat Med 9:677-684
32. Rajakumar A, Brandon HM, Daftary A, Ness R, Conrad KP (2004) Evidence for the functional activity of hypoxia-inducible transcription factors overexpressed in preeclamptic placentae. Placenta 25:763-769
33. Teramo KA, Hiilesmaa VK, Schwartz R, Clemons GK, Widness JA (2004) Amniotic fluid and cord plasma erythropoietin levels in pregnancies complicated by preeclampsia, pregnancy-induced hypertension and chronic hypertension. J Perinat Med 32:240-247
34. Devergne O, Coulomb-L'Hermine A, Capel F, Moussa M, Capron F (2001) Expression of Epstein-Barr virus-induced gene 3, an interleukin-12 p40-related molecule, throughout human pregnancy: involvement of syncytiotrophoblasts and extravillous trophoblasts. Am J Pathol 159:1763-1776
35. Blobel CP (2005) ADAMs: key components in EGFR signalling and development. Nat Rev Mol Cell Biol 6:32-43
36. Evans JP (2001) Fertilin beta and other ADAMs as integrin ligands: insights into cell adhesion and fertilization. BioEssays 23:628-639
37. Ito N, Nomura S, Iwase A, Ito T, Kikkawa F, Tsujimoto M, Ishiura S, Mizutani S (2004) ADAMs, a disintegrin and metalloproteinases, mediate shedding of oxytocinase. Biochem Biophys Res Commun 314:1008-1013
38. Leach RE, Romero R, Kim YM, Chaiworapongsa T, Kilburn B, Das SK, Dey SK, Johnson A, Qureshi F, Jacques S, Armant DR (2002) Pre-eclampsia and expression of heparin-binding EGF-like growth factor. Lancet 360:1215-1219
39. Asakura M, Kitakaze M, Takashima S, Liao Y, Ishikura F, Yoshinaka T, Ohmoto H, Node K, Yoshino K, Ishiguro H, Asanuma H, Sanada S, Matsumura Y, Takeda H, Beppu S, Tada M, Hori M, Higashiyama S (2002) Cardiac hypertrophy is inhibited by antagonism of ADAM12 processing of HB-EGF: metalloproteinase inhibitors as a new therapy. Nat Med 8:35-40
40. Kodama T, Ikeda E, Okada A, Ohtsuka T, Shimoda M, Shiomi T, Yoshida K, Nakada M, Ohuchi E, Okada Y (2004) ADAM12 is selectively overexpressed in human glioblastomas and is associated with glioblastoma cell proliferation and shedding of heparin-binding epidermal growth factor. Am J Pathol 165:1743-1753
41. Korff T, Krauss T, Augustin HG (2004) Three-dimensional spheroidal culture of cytotrophoblast cells mimics the phenotype and differentiation of cytotrophoblasts from normal and preeclamptic pregnancies. Exp Cell Res 297:415-423