Antimicrobial peptide rCRAMP induced glial cell activation through P2Y receptor signalling pathways

Molecular Immunology

Volumn 47, Issue 10, 2010, Pages 1905-1913

  Brandenburg, Lars Ove ^a,b   Jansen, Sandra ^a   Wruck, Christoph J ^a   Lucius, Ralph ^b   Pufe, Thomas ^a  

^a UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

^b UNIVERSITY OF KIEL   (Germany)

Author keywords

Antimicrobial peptide; Cathelicidin; Glial cells; Inflammation; Neuroprotection; Purinergic receptor

Indexed keywords

CYCLIC AMP; CYTOKINE; FORMYLPEPTIDE RECEPTOR LIKE 1; GLYCYLLEUCYLLEUCYLARGINYLLYSYLGLYCYLGLYCYLGLUTAMYLLYSYLPHENYLALANYLGLYCYLGLUTAMYLLYSYLLEUCYLARGINYLLYSYLISOLEUCYLGLYCYLGLUTAMINYLLYSYLISOLEUCYLLYSYLASPARTYLPHENYLALANYLPHENYLALANYLGLUTAMINYLLYSYLLEUCYLALANYLPROLYLGLUTAMYLISOLEUCYLGLUTAMYLGLUTAMINE; INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NEUROTROPHIC FACTOR; PEPTIDE; PROTEIN INHIBITOR; PURINERGIC P2X RECEPTOR; PURINERGIC P2Y RECEPTOR; PURINERGIC P2Y11 RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; ASTROCYTE; BRAIN CELL; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME PHOSPHORYLATION; GLIA CELL; INNATE IMMUNITY; MICROGLIA; NERVE CELL STIMULATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; SIGNAL TRANSDUCTION;

ANIMALS; ANTIMICROBIAL CATIONIC PEPTIDES; BLOTTING, WESTERN; CYTOKINES; IMMUNOHISTOCHEMISTRY; NEUROGLIA; NF-KAPPA B; P38 MITOGEN-ACTIVATED PROTEIN KINASES; RATS; RATS, WISTAR; RECEPTORS, PURINERGIC P2; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

RATTUS;

EID: 77952541658     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2010.03.012     Document Type: Article

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