Role of glial cells in the functional expression of LL-37/rat cathelin-related antimicrobial peptide in meningitis

Journal of Neuropathology and Experimental Neurology

Volumn 67, Issue 11, 2008, Pages 1041-1054

  Brandenburg, Lars Ove ^a,b,g   Varoga, Deike ^c   Nicolaeva, Nicoletta ^b   Leib, Stephen L ^d   Wilms, Henrik ^e   Podschun, Rainer ^f   Wruck, Christoph J ^a,b   Schröder, Jens Michael ^c   Pufe, Thomas ^a,b   Lucius, Ralph ^b  

^a RWTH AACHEN UNIVERSITY   (Germany)

^b UNIVERSITY OF KIEL   (Germany)

^c UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

^d UNIVERSITY OF BERN   (Switzerland)

^e Department of Neurology ^*

^f Institute of Infection Medicine   (Germany)

^g UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

Author keywords

Antimicrobial peptides; Bacterial; Glial cells; Inflammation; Meningitis; Neuroimmunology

Indexed keywords

CATHELICIDIN ANTIMICROBIAL PEPTIDE LL 37; INTERLEUKIN 1BETA; TUMOR NECROSIS FACTOR; ANTIINFECTIVE AGENT; ANTIMICROBIAL CATIONIC PEPTIDE; CAP18 LIPOPOLYSACCHARIDE BINDING PROTEIN; CAP18 LIPOPOLYSACCHARIDE-BINDING PROTEIN; LYSOZYME; MESSENGER RNA; NITRITE; UNCLASSIFIED DRUG;

ADOLESCENT; ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIMICROBIAL ACTIVITY; ARTICLE; ASTROCYTE; BACTERIAL MENINGITIS; BACTERICIDAL ACTIVITY; CELL FUNCTION; CENTRAL NERVOUS SYSTEM INFECTION; CEREBROSPINAL FLUID; CHOROID PLEXUS; CLINICAL ARTICLE; CONTROLLED STUDY; EPENDYMA CELL; EXPERIMENTAL MODEL; FEMALE; GLIA CELL; HUMAN; IMMUNOHISTOCHEMISTRY; INCUBATION TIME; INNATE IMMUNITY; MALE; MICROGLIA; NONHUMAN; PATHOGENESIS; PNEUMOCOCCAL INFECTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; REAL TIME POLYMERASE CHAIN REACTION; SECRETION; SIGNAL TRANSDUCTION; STREPTOCOCCUS PNEUMONIAE; SUPERNATANT; WESTERN BLOTTING; AGED; ANIMAL; BLOOD; BRAIN; CELL CULTURE; CYTOLOGY; DISEASE MODEL; DRUG EFFECT; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; GENETICS; GLIA; METABOLISM; MICROBIOLOGY; MIDDLE AGED; NEWBORN; PHYSIOLOGY; TIME; WISTAR RAT;

ADOLESCENT; ADULT; AGED; ANIMALS; ANIMALS, NEWBORN; ANTI-BACTERIAL AGENTS; ANTIMICROBIAL CATIONIC PEPTIDES; BRAIN; CELLS, CULTURED; DISEASE MODELS, ANIMAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GENE EXPRESSION; HUMANS; MALE; MENINGITIS, PNEUMOCOCCAL; MIDDLE AGED; MURAMIDASE; NEUROGLIA; NITRITES; RATS; RATS, WISTAR; RNA, MESSENGER; TIME FACTORS; YOUNG ADULT;

EID: 58149218635     PISSN: 00223069     EISSN: None     Source Type: Journal    
DOI: 10.1097/NEN.0b013e31818b4801     Document Type: Article

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