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Volumn 35, Issue 3, 2010, Pages 294-303

Duloxetine: A review of its pharmacology and use in chronic pain management

Author keywords

[No Author keywords available]

Indexed keywords

AMFEBUTAMONE; AMITRIPTYLINE; ANTIARRHYTHMIC AGENT; ANTICONVULSIVE AGENT; ANTIDEPRESSANT AGENT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CIMETIDINE; CODEINE; DESIPRAMINE; DULOXETINE; FLUOXETINE; FLUVOXAMINE; GABAPENTIN; PAROXETINE; PHENOTHIAZINE DERIVATIVE; PLACEBO; PREGABALIN; QUINIDINE; QUINOLINE DERIVED ANTIINFECTIVE AGENT; SEROTONIN NORADRENALIN REUPTAKE INHIBITOR; SEROTONIN UPTAKE INHIBITOR; TRAMADOL; TRICYCLIC ANTIDEPRESSANT AGENT; VENLAFAXINE; WARFARIN;

EID: 77952328473     PISSN: 10987339     EISSN: None     Source Type: Journal    
DOI: 10.1097/AAP.0b013e3181df2645     Document Type: Review
Times cited : (60)

References (82)
  • 1
    • 35748943212 scopus 로고    scopus 로고
    • Pharmacologic management of neuropathic pain: Evidence-based recommendations
    • Iskedijan M, Einarson TR, Walker JH, et al. Pharmacologic management of neuropathic pain: evidence-based recommendations. Pain. 2007;132:237-251.
    • (2007) Pain , vol.132 , pp. 237-251
    • Iskedijan, M.1    Einarson, T.R.2    Walker, J.H.3
  • 2
    • 33645689140 scopus 로고    scopus 로고
    • Consensus guidelines: Treatment planning and options. Diabetic peripheral neuropathic pain
    • Argoff CE, Backonja MM, Belgrade MJ, et al. Consensus guidelines: treatment planning and options. Diabetic peripheral neuropathic pain. Mayo Clin Proc. 2006;81: S12-S25.
    • (2006) Mayo Clin. Proc. , vol.81
    • Argoff, C.E.1    Backonja, M.M.2    Belgrade, M.J.3
  • 3
    • 33750048137 scopus 로고    scopus 로고
    • EFNS guidelines on pharmacological treatment of neuropathic pain
    • Attal N, Cruccu G, Haanpaa M, et al. EFNS guidelines on pharmacological treatment of neuropathic pain. Eur J Neurol. 2006;13:1153-1169.
    • (2006) Eur. J. Neurol. , vol.13 , pp. 1153-1169
    • Attal, N.1    Cruccu, G.2    Haanpaa, M.3
  • 4
    • 34248591500 scopus 로고    scopus 로고
    • Pharmacological management of chronic neuropathic pain-consensus statement and guidelines from the canadian pain society
    • Moulin DE, Clark AJ, Gilron I, et al. Pharmacological management of chronic neuropathic pain-consensus statement and guidelines from the canadian pain society. Pain Res Manag. 2007;12:13-21.
    • (2007) Pain Res. Manag. , vol.12 , pp. 13-21
    • Moulin, D.E.1    Clark, A.J.2    Gilron, I.3
  • 5
    • 0036603005 scopus 로고    scopus 로고
    • Chronic pain and medullary descending facilitation
    • Porreca F, Ossipov MH, Gebhart GF. Chronic pain and medullary descending facilitation. Trends Neurosci. 2002;25:319-325.
    • (2002) Trends Neurosci. , vol.25 , pp. 319-325
    • Porreca, F.1    Ossipov, M.H.2    Gebhart, G.F.3
  • 6
    • 0036277865 scopus 로고    scopus 로고
    • Descending control of pain
    • Millan MJ. Descending control of pain. Prog Neurobiol. 2002;66:355-474.
    • (2002) Prog. Neurobiol. , vol.66 , pp. 355-474
    • Millan, M.J.1
  • 7
    • 33750630238 scopus 로고    scopus 로고
    • Noradrenergic pain modulation
    • Pertovaara A. Noradrenergic pain modulation. Prog Neurobiol. 2006;80:53-83.
    • (2006) Prog. Neurobiol. , vol.80 , pp. 53-83
    • Pertovaara, A.1
  • 8
    • 6244309292 scopus 로고    scopus 로고
    • Efficacy of duloxetine, a potent and balanced serotonin-norepinephrine reuptake inhibitor in persistent pain models in rats
    • Iyengar S, Webster AA, Hemrick-Luecke SK, Xu JY, Simmons RM. Efficacy of duloxetine, a potent and balanced serotonin-norepinephrine reuptake inhibitor in persistent pain models in rats. J Pharmacol Exp Ther. 2004;311:576-584.
    • (2004) J. Pharmacol. Exp. Ther. , vol.311 , pp. 576-584
    • Iyengar, S.1    Webster, A.A.2    Hemrick-Luecke, S.K.3    Xu, J.Y.4    Simmons, R.M.5
  • 9
    • 13244284671 scopus 로고    scopus 로고
    • Efficacy of duloxetine, a potent and balanced serotonergic and noradrenergic reuptake inhibitor, in inflammatory and acute pain models in rodents
    • Jones CK, Peters SC, Shannon HE. Efficacy of duloxetine, a potent and balanced serotonergic and noradrenergic reuptake inhibitor, in inflammatory and acute pain models in rodents. J Pharmacol Exp Ther. 2005;312:726-732.
    • (2005) J. Pharmacol. Exp. Ther. , vol.312 , pp. 726-732
    • Jones, C.K.1    Peters, S.C.2    Shannon, H.E.3
  • 10
    • 33751440393 scopus 로고    scopus 로고
    • Synergistic interactions between the dual serotonergic, noradrenergic reuptake inhibitor duloxetine and the non-steroidal anti-inflammatory drug ibuprofen in inflammatory pain in rodents
    • Jones CK, Peters SC, Shannon HE. Synergistic interactions between the dual serotonergic, noradrenergic reuptake inhibitor duloxetine and the non-steroidal anti-inflammatory drug ibuprofen in inflammatory pain in rodents. Eur J Pain. 2007;11:208-215.
    • (2007) Eur. J. Pain , vol.11 , pp. 208-215
    • Jones, C.K.1    Peters, S.C.2    Shannon, H.E.3
  • 11
    • 33750813848 scopus 로고    scopus 로고
    • Comparison of antinociceptive actions of standard analgesics in attenuating capsaicin and nerve-injury-induced mechanical hypersensitivity
    • Joshi SK, Hernandez G, Mikusa JP, et al. Comparison of antinociceptive actions of standard analgesics in attenuating capsaicin and nerve-injury-induced mechanical hypersensitivity. Neuroscience. 2006;143:587-596.
    • (2006) Neuroscience , vol.143 , pp. 587-596
    • Joshi, S.K.1    Hernandez, G.2    Mikusa, J.P.3
  • 12
    • 13444287930 scopus 로고    scopus 로고
    • Antinociceptive effects of the antidepressants amitriptyline, duloxetine, mirtazapine and citalopram in animal models of acute, persistent and neuropathic pain
    • Bomholt SF, Mikkelsen JD, Blackburn-Munro G. Antinociceptive effects of the antidepressants amitriptyline, duloxetine, mirtazapine and citalopram in animal models of acute, persistent and neuropathic pain. Neuropharmacology. 2005;48:252-263.
    • (2005) Neuropharmacology , vol.48 , pp. 252-263
    • Bomholt, S.F.1    Mikkelsen, J.D.2    Blackburn-Munro, G.3
  • 13
    • 20444464304 scopus 로고    scopus 로고
    • Duloxetine vs. placebo in patients with painful diabetic neuropathy
    • Goldstein DJ, Lu Y, Detke MJ, Lee TC, Iyengar S. Duloxetine vs. placebo in patients with painful diabetic neuropathy. Pain. 2005;116:109-118.
    • (2005) Pain , vol.116 , pp. 109-118
    • Goldstein, D.J.1    Lu, Y.2    Detke, M.J.3    Lee, T.C.4    Iyengar, S.5
  • 14
    • 28444459170 scopus 로고    scopus 로고
    • A double-blind, randomized multicenter trial comparing duloxetine with placebo in the management of diabetic peripheral neuropathic pain
    • Raskin J, Pritchett YL, Wang F, et al. A double-blind, randomized multicenter trial comparing duloxetine with placebo in the management of diabetic peripheral neuropathic pain. Pain Med. 2005;6:346-356.
    • (2005) Pain Med. , vol.6 , pp. 346-356
    • Raskin, J.1    Pritchett, Y.L.2    Wang, F.3
  • 15
    • 33750341692 scopus 로고    scopus 로고
    • A randomized controlled trial of duloxetine in diabetic peripheral neuropathic pain
    • Wernicke JF, Pritchett YL, D'Souza DN, et al. A randomized controlled trial of duloxetine in diabetic peripheral neuropathic pain. Neurology. 2006;67:1411-1420.
    • (2006) Neurology , vol.67 , pp. 1411-1420
    • Wernicke, J.F.1    Pritchett, Y.L.2    D'Souza, D.N.3
  • 16
    • 7044229576 scopus 로고    scopus 로고
    • Duloxetine 60 mg once-daily in the treatment of painful physical symptoms in patients with major depressive disorder
    • Brannan SK, Mallinckrodt CH, Brown EB, et al. Duloxetine 60 mg once-daily in the treatment of painful physical symptoms in patients with major depressive disorder. J Psychiatr Res. 2005;39:43-53.
    • (2005) J. Psychiatr. Res. , vol.39 , pp. 43-53
    • Brannan, S.K.1    Mallinckrodt, C.H.2    Brown, E.B.3
  • 17
    • 37049001394 scopus 로고    scopus 로고
    • Efficacy and safety of duloxetine 60 mg once daily in the treatment of pain in patients with major depressive disorder and at least moderate pain of unknown etiology: A randomized controlled trial
    • Brecht S, Courtecuisse C, Debieuvre C, et al. Efficacy and safety of duloxetine 60 mg once daily in the treatment of pain in patients with major depressive disorder and at least moderate pain of unknown etiology: a randomized controlled trial. J Clin Psychiatry. 2007;68:1707-1716.
    • (2007) J. Clin. Psychiatry , vol.68 , pp. 1707-1716
    • Brecht, S.1    Courtecuisse, C.2    Debieuvre, C.3
  • 18
    • 4444381930 scopus 로고    scopus 로고
    • A double-blind, multicenter trial comparing duloxetine with placebo in the treatment of fibromyalgia patients with or without major depressive disorder
    • Arnold LM, Lu Y, Crofford LJ, et al. A double-blind, multicenter trial comparing duloxetine with placebo in the treatment of fibromyalgia patients with or without major depressive disorder. Arthritis Rheum. 2004;50:2974-2984.
    • (2004) Arthritis Rheum. , vol.50 , pp. 2974-2984
    • Arnold, L.M.1    Lu, Y.2    Crofford, L.J.3
  • 19
    • 28644442626 scopus 로고    scopus 로고
    • A randomized, double-blind, placebo-controlled trial of duloxetine in the treatment of women with fibromyalgia with or without major depressive disorder
    • Arnold LM, Rosen A, Pritchett YL, et al. A randomized, double-blind, placebo-controlled trial of duloxetine in the treatment of women with fibromyalgia with or without major depressive disorder. Pain. 2005;119:5-15.
    • (2005) Pain , vol.119 , pp. 5-15
    • Arnold, L.M.1    Rosen, A.2    Pritchett, Y.L.3
  • 20
    • 43549091316 scopus 로고    scopus 로고
    • Efficacy and safety of duloxetine for treatment of fibromyalgia in patients with or without major depressive disorder: Results from a 6-month, randomized, double-blind, placebo-controlled, fixed-dose trial
    • Russell IJ, Mease PJ, Smith TR, et al. Efficacy and safety of duloxetine for treatment of fibromyalgia in patients with or without major depressive disorder: results from a 6-month, randomized, double-blind, placebo-controlled, fixed-dose trial. Pain. 2008;136:432-444.
    • (2008) Pain , vol.136 , pp. 432-444
    • Russell, I.J.1    Mease, P.J.2    Smith, T.R.3
  • 21
    • 16644401850 scopus 로고    scopus 로고
    • New drug for neuropathic pain
    • New drug for neuropathic pain. FDA Consumer. 2004;38:2.
    • (2004) FDA Consumer , vol.38 , pp. 2
  • 22
    • 77952346397 scopus 로고    scopus 로고
    • Available at:, Accessed March 1
    • Food and Drug Administration. NDA approval letter. Available at: http://www.fda.gov/cder/foi/appletter/2008/022148s000ltrpdf. Accessed March 1, 2009.
    • (2009) NDA Approval Letter
  • 23
    • 18844370877 scopus 로고    scopus 로고
    • The dual transporter inhibitor duloxetine: A review of its preclinical pharmacology, pharmacokinetic profile, and clinical results in depression
    • Bymaster FP, Lee TC, Knadler MP, Detke MJ, Iyengar S. The dual transporter inhibitor duloxetine: a review of its preclinical pharmacology, pharmacokinetic profile, and clinical results in depression. Curr Pharm Des. 2005;11:1475-1493.
    • (2005) Curr. Pharm. Des. , vol.11 , pp. 1475-1493
    • Bymaster, F.P.1    Lee, T.C.2    Knadler, M.P.3    Detke, M.J.4    Iyengar, S.5
  • 24
    • 0041856533 scopus 로고    scopus 로고
    • Metabolism, excretion, and pharmacokinetics of duloxetine in healthy human subjects
    • Lantz RJ, Gillespie TA, Rash TJ, et al. Metabolism, excretion, and pharmacokinetics of duloxetine in healthy human subjects. Drug Metab Dispos. 2003;31:1142-1150.
    • (2003) Drug Metab. Dispos , vol.31 , pp. 1142-1150
    • Lantz, R.J.1    Gillespie, T.A.2    Rash, T.J.3
  • 25
    • 0033674519 scopus 로고    scopus 로고
    • Pharmacokinetics and safety of duloxetine, a dual-serotonin and norepinephrine reuptake inhibitor
    • Sharma A, Goldberg MJ, Cerimele BJ. Pharmacokinetics and safety of duloxetine, a dual-serotonin and norepinephrine reuptake inhibitor. J Clin Pharmacol. 2000;40:161-167.
    • (2000) J. Clin. Pharmacol. , vol.40 , pp. 161-167
    • Sharma, A.1    Goldberg, M.J.2    Cerimele, B.J.3
  • 26
    • 77952365469 scopus 로고    scopus 로고
    • Eli Lilly Canada Inc, Toronto, Ontario, Canada: Eli Lilly Canada Inc
    • Eli Lilly Canada Inc. CYMBALTA: Product Monograph. Toronto, Ontario, Canada: Eli Lilly Canada Inc; 2007.
    • (2007) CYMBALTA: Product Monograph
  • 27
    • 68349112817 scopus 로고    scopus 로고
    • Review of duloxetine and venlafaxine in depression
    • Zerjav S, Tse G, Scott M J W. Review of duloxetine and venlafaxine in depression. CPJ. 2009;142:144-152.
    • (2009) CPJ , vol.142 , pp. 144-152
    • Zerjav, S.1    Tse, G.2    Scott, M.J.W.3
  • 28
    • 33645500817 scopus 로고    scopus 로고
    • Interaction of duloxetine and warfarin causing severe elevation of international normalized ratio
    • Glueck CJ, Khalil Q, Winiarska M, Wang P. Interaction of duloxetine and warfarin causing severe elevation of international normalized ratio. JAMA. 2006;295:1517-1518.
    • (2006) JAMA , vol.295 , pp. 1517-1518
    • Glueck, C.J.1    Khalil, Q.2    Winiarska, M.3    Wang, P.4
  • 29
    • 42949165178 scopus 로고    scopus 로고
    • In vitro and in vivo evaluations of cytochrome P450 1A2 interactions with duloxetine
    • Lobo ED, Bergstrom RF, Reddy S, et al. In vitro and in vivo evaluations of cytochrome P450 1A2 interactions with duloxetine. Clin Pharmacokinet. 2008;47:191-202.
    • (2008) Clin. Pharmacokinet. , vol.47 , pp. 191-202
    • Lobo, E.D.1    Bergstrom, R.F.2    Reddy, S.3
  • 30
    • 0037374043 scopus 로고    scopus 로고
    • Duloxetine is both an inhibitor and a substrate of cytochrome P450 2D6 in healthy volunteers
    • Skinner MH, Kuan HY, Pan A, et al. Duloxetine is both an inhibitor and a substrate of cytochrome P450 2D6 in healthy volunteers. Clin Pharmacol Ther. 2003;73:170-177.
    • (2003) Clin. Pharmacol. Ther. , vol.73 , pp. 170-177
    • Skinner, M.H.1    Kuan, H.Y.2    Pan, A.3
  • 31
    • 0027475388 scopus 로고
    • LY248686, a new inhibitor of serotonin and norepinephrine uptake
    • Wong DT, Bymaster FP, Mayle DA, et al. LY248686, a new inhibitor of serotonin and norepinephrine uptake. Neuropsychopharmacology. 1993;8:23-33.
    • (1993) Neuropsychopharmacology , vol.8 , pp. 23-33
    • Wong, D.T.1    Bymaster, F.P.2    Mayle, D.A.3
  • 32
    • 0035677108 scopus 로고    scopus 로고
    • Comparative affinity of duloxetine and venlafaxine for serotonin and norepinephrine transporters in vitro and in vivo, human serotonin receptor subtypes, and other neuronal receptors
    • Bymaster FP, Dreshfield-Ahmad LJ, Threlkeld PG, et al. Comparative affinity of duloxetine and venlafaxine for serotonin and norepinephrine transporters in vitro and in vivo, human serotonin receptor subtypes, and other neuronal receptors. Neuropsychopharmacology. 2001;25:871-880.
    • (2001) Neuropsychopharmacology , vol.25 , pp. 871-880
    • Bymaster, F.P.1    Dreshfield-Ahmad, L.J.2    Threlkeld, P.G.3
  • 33
    • 0030424363 scopus 로고    scopus 로고
    • Blockade of the serotonin and norepinephrine uptake processes by duloxetine: In vitro and in vivo studies in the rat brain
    • Kasamo K, Blier P, De Montigny C. Blockade of the serotonin and norepinephrine uptake processes by duloxetine: in vitro and in vivo studies in the rat brain. J Pharmacol Exp Ther. 1996;277:278-286.
    • (1996) J. Pharmacol. Exp. Ther. , vol.277 , pp. 278-286
    • Kasamo, K.1    Blier, P.2    De Montigny, C.3
  • 34
    • 0032524235 scopus 로고    scopus 로고
    • Affinities of venlafaxine and various reuptake inhibitors for the serotonin and norepinephrine transporters
    • Beique JC, Lavoie N, de Montigny C, Debonnel G. Affinities of venlafaxine and various reuptake inhibitors for the serotonin and norepinephrine transporters. Eur J Pharmacol. 1998;349:129-132.
    • (1998) Eur. J. Pharmacol. , vol.349 , pp. 129-132
    • Beique, J.C.1    Lavoie, N.2    De Montigny, C.3    Debonnel, G.4
  • 35
    • 0142059144 scopus 로고    scopus 로고
    • Comparison of effects of dual transporter inhibitors on monoamine transporters and extracellular levels in rats
    • Koch S, Hemrick-Luecke SK, Thompson LK, et al. Comparison of effects of dual transporter inhibitors on monoamine transporters and extracellular levels in rats. Neuropharmacology. 2003;45:935-944.
    • (2003) Neuropharmacology , vol.45 , pp. 935-944
    • Koch, S.1    Hemrick-Luecke, S.K.2    Thompson, L.K.3
  • 36
    • 0026522154 scopus 로고
    • Effects of desipramine, amitriptyline, and fluoxetine on pain in diabetic neuropathy
    • Max MB, Lynch SA, Muir J, et al. Effects of desipramine, amitriptyline, and fluoxetine on pain in diabetic neuropathy. N Engl J Med. 1992;326:1250-1256.
    • (1992) N. Engl. J. Med. , vol.326 , pp. 1250-1256
    • Max, M.B.1    Lynch, S.A.2    Muir, J.3
  • 37
    • 0032729936 scopus 로고    scopus 로고
    • Efficacy of pharmacological treatments of neuropathic pain: An update and effect related to mechanism of drug action
    • Sindrup SH, Jensen TS. Efficacy of pharmacological treatments of neuropathic pain: an update and effect related to mechanism of drug action. Pain. 1999;83:389-400.
    • (1999) Pain , vol.83 , pp. 389-400
    • Sindrup, S.H.1    Jensen, T.S.2
  • 38
    • 0033944573 scopus 로고    scopus 로고
    • Evidence-based data on pain relief with antidepressants
    • Fishbain D. Evidence-based data on pain relief with antidepressants. Ann Med. 2000;32:305-316.
    • (2000) Ann. Med. , vol.32 , pp. 305-316
    • Fishbain, D.1
  • 39
    • 6344285317 scopus 로고    scopus 로고
    • Serotonin and noradrenaline reuptake inhibitors in animal models of pain
    • Mochizucki D. Serotonin and noradrenaline reuptake inhibitors in animal models of pain. Hum Psychopharmacol. 2004;19(suppl 1): S15-S19.
    • (2004) Hum. Psychopharmacol. , vol.19 , Issue.1 SUPPL.
    • Mochizucki, D.1
  • 41
    • 38049032270 scopus 로고    scopus 로고
    • A comparison of initial duloxetine dosing strategies in patients with major depressive disorder
    • Whitmyer VG, Dunner DL, Kornstein SG, et al. A comparison of initial duloxetine dosing strategies in patients with major depressive disorder. J Clin Psychiatry. 2007;68:1921-1930.
    • (2007) J. Clin. Psychiatry , vol.68 , pp. 1921-1930
    • Whitmyer, V.G.1    Dunner, D.L.2    Kornstein, S.G.3
  • 42
    • 35348826316 scopus 로고    scopus 로고
    • A randomized, double-blind comparison of duloxetine and venlafaxine in the treatment of patients with major depressive disorder
    • Perahia DG, Pritchett YL, Kajdasz DK, et al. A randomized, double-blind comparison of duloxetine and venlafaxine in the treatment of patients with major depressive disorder. J Psychiatr Res. 2008;42:22-34.
    • (2008) J. Psychiatr. Res. , vol.42 , pp. 22-34
    • Perahia, D.G.1    Pritchett, Y.L.2    Kajdasz, D.K.3
  • 43
    • 37349086775 scopus 로고    scopus 로고
    • Duloxetine for the management of diabetic peripheral neuropathic pain: Evidence-based findings from post hoc analysis of three multicenter, randomized, double-blind, placebo-controlled, parallel-group studies
    • Kajdasz DK, Iyengar S, Desaiah D, et al. Duloxetine for the management of diabetic peripheral neuropathic pain: evidence-based findings from post hoc analysis of three multicenter, randomized, double-blind, placebo-controlled, parallel-group studies. Clin Ther. 2007;29(suppl): 2536-2546.
    • (2007) Clin. Ther. , vol.29 , Issue.SUPPL. , pp. 2536-2546
    • Kajdasz, D.K.1    Iyengar, S.2    Desaiah, D.3
  • 44
    • 66749155881 scopus 로고    scopus 로고
    • Hepatic effects of duloxetine-I: Non-clinical and clinical trial data
    • Wernicke J, Pangallo B, Wang F, et al. Hepatic effects of duloxetine-I: non-clinical and clinical trial data. Curr Drug Saf. 2008;3:132-142.
    • (2008) Curr. Drug Saf. , vol.3 , pp. 132-142
    • Wernicke, J.1    Pangallo, B.2    Wang, F.3
  • 45
    • 66749119940 scopus 로고    scopus 로고
    • Hepatic effects of duloxetine-II: Spontaneous reports and epidemiology of hepatic events
    • Wernicke J, Acharya N, Strombom I, et al. Hepatic effects of duloxetine-II: spontaneous reports and epidemiology of hepatic events. Curr Drug Saf. 2008;3:143-153.
    • (2008) Curr. Drug Saf. , vol.3 , pp. 143-153
    • Wernicke, J.1    Acharya, N.2    Strombom, I.3
  • 46
    • 66749083239 scopus 로고    scopus 로고
    • Hepatic effects of duloxetine-III: Analysis of hepatic events using external data sources
    • Strombom I, Wernicke JF, Seeger J, D'Souza DN, Acharya N. Hepatic effects of duloxetine-III: analysis of hepatic events using external data sources. Curr Drug Saf. 2008;3:154-162.
    • (2008) Curr. Drug Saf. , vol.3 , pp. 154-162
    • Strombom, I.1    Wernicke, J.F.2    Seeger, J.3    D'Souza, D.N.4    Acharya, N.5
  • 48
    • 54049140072 scopus 로고    scopus 로고
    • Answers to the most common questions about the hepatic safety profile of duloxetine
    • Wohlreich MM, Acharya N, Strombom I, et al. Answers to the most common questions about the hepatic safety profile of duloxetine. Postgrad Med. 2008;120:111-118.
    • (2008) Postgrad Med. , vol.120 , pp. 111-118
    • Wohlreich, M.M.1    Acharya, N.2    Strombom, I.3
  • 50
    • 15444376068 scopus 로고    scopus 로고
    • Cardiovascular profile of duloxetine, a dual reuptake inhibitor of serotonin and norepinephrine
    • Thase ME, Tran PV, Wiltse C, et al. Cardiovascular profile of duloxetine, a dual reuptake inhibitor of serotonin and norepinephrine. J Clin Psychopharmacol. 2005;25:132-140.
    • (2005) J. Clin. Psychopharmacol. , vol.25 , pp. 132-140
    • Thase, M.E.1    Tran, P.V.2    Wiltse, C.3
  • 51
    • 34248329070 scopus 로고    scopus 로고
    • An evaluation of the cardiovascular safety profile of duloxetine: Findings from 42 placebo-controlled studies
    • Wernicke J, Lledo A, Raskin J, Kajdasz DK, Wang F. An evaluation of the cardiovascular safety profile of duloxetine: findings from 42 placebo-controlled studies. Drug Saf. 2007;30:437-455.
    • (2007) Drug Saf. , vol.30 , pp. 437-455
    • Wernicke, J.1    Lledo, A.2    Raskin, J.3    Kajdasz, D.K.4    Wang, F.5
  • 53
    • 0344701672 scopus 로고    scopus 로고
    • Treatment with antidepressants
    • Mitchell CW, Kairis LR, Glazer A, et al, 4th ed. Philadelphia, PA: Lippincott Williams & Wilkins
    • Janicak PG, Davis JM, Preskorn SH, et al. Treatment with antidepressants. In: Mitchell CW, Kairis LR, Glazer A, et al. Principles and Practice of Psychopharmacotherapy. 4th ed. Philadelphia, PA: Lippincott Williams & Wilkins; 2006.
    • (2006) Principles and Practice of Psychopharmacotherapy
    • Janicak, P.G.1    Davis, J.M.2    Preskorn, S.H.3
  • 54
    • 33845616340 scopus 로고    scopus 로고
    • Serotonin syndrome from the interaction of cyclobenzaprine with other serotoninergic drugs
    • Keegan MT, Brown DR, Rabinstein AA. Serotonin syndrome from the interaction of cyclobenzaprine with other serotoninergic drugs. Anesth Analg. 2006;103:1466-1468.
    • (2006) Anesth. Analg. , vol.103 , pp. 1466-1468
    • Keegan, M.T.1    Brown, D.R.2    Rabinstein, A.A.3
  • 57
    • 44649136013 scopus 로고    scopus 로고
    • Heart failure worsening and exacerbation after venlafaxine and duloxetine therapy
    • Colucci VJ, Berry BD. Heart failure worsening and exacerbation after venlafaxine and duloxetine therapy. Ann Pharmacother. 2008;42:882-887.
    • (2008) Ann. Pharmacother. , vol.42 , pp. 882-887
    • Colucci, V.J.1    Berry, B.D.2
  • 59
    • 34248581090 scopus 로고    scopus 로고
    • Recurrent hyponatremia after substitution of citalopram with duloxetine
    • Dirks AC, van Hyfte DM. Recurrent hyponatremia after substitution of citalopram with duloxetine. J Clin Psychopharmacol. 2007;27:313.
    • (2007) J. Clin. Psychopharmacol. , vol.27 , pp. 313
    • Dirks, A.C.1    Van Hyfte, D.M.2
  • 60
    • 33846215883 scopus 로고    scopus 로고
    • Duloxetine and hyponatremia: A report of 5 cases
    • Kruger S, Lindstaedt M. Duloxetine and hyponatremia: a report of 5 cases. J Clin Psychopharmacol. 2007;27:101-104.
    • (2007) J. Clin. Psychopharmacol. , vol.27 , pp. 101-104
    • Kruger, S.1    Lindstaedt, M.2
  • 61
    • 33645878302 scopus 로고    scopus 로고
    • Duloxetine-induced syndrome of inappropriate antidiuretic hormone secretion and seizures
    • Maramattom BV. Duloxetine-induced syndrome of inappropriate antidiuretic hormone secretion and seizures. Neurology. 2006;66:773-774.
    • (2006) Neurology , vol.66 , pp. 773-774
    • Maramattom, B.V.1
  • 62
  • 64
    • 33847689424 scopus 로고    scopus 로고
    • An acute attack of porphyria in a patient taking duloxetine
    • Loper T, Touchet B. An acute attack of porphyria in a patient taking duloxetine. Psychosomatics. 2007;48:179-180.
    • (2007) Psychosomatics , vol.48 , pp. 179-180
    • Loper, T.1    Touchet, B.2
  • 65
    • 51349119038 scopus 로고    scopus 로고
    • Duloxetine for painful diabetic neuropathy and fibromyalgia pain: Systematic review of randomised trials
    • Sultan A, Gaskell H, Derry S, Moore RA. Duloxetine for painful diabetic neuropathy and fibromyalgia pain: systematic review of randomised trials. BMC Neurol. 2008;8:29.
    • (2008) BMC Neurol. , vol.8 , pp. 29
    • Sultan, A.1    Gaskell, H.2    Derry, S.3    Moore, R.A.4
  • 66
    • 38149071546 scopus 로고    scopus 로고
    • Review of duloxetine in the management of diabetic peripheral neuropathic pain
    • Smith T, Nicholson RA. Review of duloxetine in the management of diabetic peripheral neuropathic pain. Vasc Health Risk Manag. 2007;3:833-844.
    • (2007) Vasc. Health Risk Manag. , vol.3 , pp. 833-844
    • Smith, T.1    Nicholson, R.A.2
  • 68
    • 64049096010 scopus 로고    scopus 로고
    • Meta-analysis of duloxetine vs. pregabalin and gabapentin in the treatment of diabetic peripheral neuropathic pain
    • Quilici S, Chancellor J, Lothgren M, et al. Meta-analysis of duloxetine vs. pregabalin and gabapentin in the treatment of diabetic peripheral neuropathic pain. BMC Neurol. 2009;9:6.
    • (2009) BMC Neurol. , vol.9 , pp. 6
    • Quilici, S.1    Chancellor, J.2    Lothgren, M.3
  • 69
    • 34547448075 scopus 로고    scopus 로고
    • Duloxetine for the management of diabetic peripheral neuropathic pain: Response profile
    • Pritchett YL, McCarberg BH, Watkin JG, Robinson MJ. Duloxetine for the management of diabetic peripheral neuropathic pain: response profile. Pain Med. 2007;8:397-409.
    • (2007) Pain Med. , vol.8 , pp. 397-409
    • Pritchett, Y.L.1    McCarberg, B.H.2    Watkin, J.G.3    Robinson, M.J.4
  • 70
    • 0026612098 scopus 로고
    • Platelet 3 h-imipramine uptake receptor density and serum serotonin levels in patients with fibromyalgia/fibrositis syndrome
    • Russell IJ, Michalek JE, Vipraio GA, et al. Platelet 3 h-imipramine uptake receptor density and serum serotonin levels in patients with fibromyalgia/fibrositis syndrome. J Rheumatol. 1992;19:104-109.
    • (1992) J. Rheumatol. , vol.19 , pp. 104-109
    • Russell, I.J.1    Michalek, J.E.2    Vipraio, G.A.3
  • 71
    • 0026732553 scopus 로고
    • Cerebrospinal fluid biogenic amine metabolites in fibromyalgia/fibrositis syndrome and rheumatoid arthritis
    • Russell IJ, Vaeroy H, Javors M, Nyberg F. Cerebrospinal fluid biogenic amine metabolites in fibromyalgia/fibrositis syndrome and rheumatoid arthritis. Arthritis Rheum. 1992;35:550-556.
    • (1992) Arthritis Rheum. , vol.35 , pp. 550-556
    • Russell, I.J.1    Vaeroy, H.2    Javors, M.3    Nyberg, F.4
  • 72
    • 0026503839 scopus 로고
    • Plasma tryptophan and other amino acids in primary fibromyalgia: A controlled study
    • Yunus MB, Dailey JW, Aldag JC, Masi AT, Jobe PC. Plasma tryptophan and other amino acids in primary fibromyalgia: a controlled study. J Rheumatol. 1992;19:90-94.
    • (1992) J. Rheumatol. , vol.19 , pp. 90-94
    • Yunus, M.B.1    Dailey, J.W.2    Aldag, J.C.3    Masi, A.T.4    Jobe, P.C.5
  • 73
    • 0344938405 scopus 로고    scopus 로고
    • Relationship of substance P, 5-hydroxyindole acetic acid and tryptophan in serum of fibromyalgia patients
    • Schwarz MJ, Spath M, Muller-Bardorff H, et al. Relationship of substance P, 5-hydroxyindole acetic acid and tryptophan in serum of fibromyalgia patients. Neurosci Lett. 1999;259:196-198.
    • (1999) Neurosci. Lett. , vol.259 , pp. 196-198
    • Schwarz, M.J.1    Spath, M.2    Muller-Bardorff, H.3
  • 74
    • 0029981949 scopus 로고    scopus 로고
    • The relationship between fibromyalgia and major depressive disorder
    • Hudson JI, Pope HG Jr. The relationship between fibromyalgia and major depressive disorder. Rheum Dis Clin North Am. 1996;22:285-303.
    • (1996) Rheum. Dis. Clin. North Am. , vol.22 , pp. 285-303
    • Hudson, J.I.1    Pope Jr., H.G.2
  • 75
    • 58849121772 scopus 로고    scopus 로고
    • A single-blind, placebo run-in study of duloxetine for activity-limiting osteoarthritis pain
    • Sullivan MD, Bentley S, Fan MY, Gardner G. A single-blind, placebo run-in study of duloxetine for activity-limiting osteoarthritis pain. J Pain. 2009;10:208-213.
    • (2009) J. Pain , vol.10 , pp. 208-213
    • Sullivan, M.D.1    Bentley, S.2    Fan, M.Y.3    Gardner, G.4
  • 77
    • 34648812736 scopus 로고    scopus 로고
    • Efficacy of duloxetine as a migraine preventive medication: Possible predictors of response in a retrospective chart review
    • Taylor AP, Adelman JU, Freeman MC. Efficacy of duloxetine as a migraine preventive medication: possible predictors of response in a retrospective chart review. Headache. 2007;47:1200-1203.
    • (2007) Headache , vol.47 , pp. 1200-1203
    • Taylor, A.P.1    Adelman, J.U.2    Freeman, M.C.3
  • 78
    • 52649086326 scopus 로고    scopus 로고
    • An 8-week, open-label trial of duloxetine for comorbid major depressive disorder and chronic headache
    • Volpe FM. An 8-week, open-label trial of duloxetine for comorbid major depressive disorder and chronic headache. J Clin Psychiatry. 2008;69:1449-1454.
    • (2008) J. Clin. Psychiatry , vol.69 , pp. 1449-1454
    • Volpe, F.M.1
  • 79
    • 33646901548 scopus 로고    scopus 로고
    • Cost-effectiveness of duloxetine versus routine treatment for U. S. patients with diabetic peripheral neuropathic pain
    • Wu EQ, Birnbaum HG, Mareva MN, et al. Cost-effectiveness of duloxetine versus routine treatment for U. S. patients with diabetic peripheral neuropathic pain. J Pain. 2006;7:399-407.
    • (2006) J. Pain , vol.7 , pp. 399-407
    • Wu, E.Q.1    Birnbaum, H.G.2    Mareva, M.N.3
  • 80
    • 77952342947 scopus 로고    scopus 로고
    • Overview of anticonvulsants, serotonin-norepinephrine reuptake inhibitors, and tricyclic antidepressants in management of neuropathic pain: A meta-analysis and economic evaluation
    • Ottawa, Ontario: Canadian Agency for Drugs and Technologies in Health. Available at:, Accessed September 27
    • Overview of anticonvulsants, serotonin-norepinephrine reuptake inhibitors, and tricyclic antidepressants in management of neuropathic pain: a meta-analysis and economic evaluation. Technology Overview Number 49. Ottawa, Ontario: Canadian Agency for Drugs and Technologies in Health. Available at: www.cadth.ca/media/pdf/O0458-Management-of-Neuropathic-Pain-to-epdf. Accessed September 27, 2009.
    • (2009) Technology Overview Number , pp. 49
  • 81
    • 56549117146 scopus 로고    scopus 로고
    • A cost-utility comparison of four first-line medications in painful diabetic neuropathy
    • O'Connor AB, Noyes K, Holloway RG. A cost-utility comparison of four first-line medications in painful diabetic neuropathy. Pharmacoeconomics. 2008;26:1045-1064.
    • (2008) Pharmacoeconomics , vol.26 , pp. 1045-1064
    • O'Connor, A.B.1    Noyes, K.2    Holloway, R.G.3
  • 82
    • 60849086169 scopus 로고    scopus 로고
    • Comparative efficacy and acceptability of 12 new-generation antidepressants: A multiple-treatments meta-analysis
    • Cipriani A, Furukawa TA, Salanti G, et al. Comparative efficacy and acceptability of 12 new-generation antidepressants: a multiple-treatments meta-analysis. Lancet. 2009;373:746-758.
    • (2009) Lancet , vol.373 , pp. 746-758
    • Cipriani, A.1    Furukawa, T.A.2    Salanti, G.3


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