Understanding specificity in metabolic pathways-Structural biology of human nucleotide metabolism

Biochemical and Biophysical Research Communications

Volumn 396, Issue 1, 2010, Pages 157-163

  Welin, Martin ^a   Nordlund, Pär ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Metabolic pathway; Negative selectivity; Nucleotide metabolism; Specificity determinants; Structural biology; Substrate specificity

Indexed keywords

ADENOSINE KINASE; ADENYLOSUCCINATE LYASE; ADENYLOSUCCINATE SYNTHASE; ASPARTATE CARBAMOYLTRANSFERASE; CARBAMOYL PHOSPHATE SYNTHASE; DIHYDROOROTASE; GUANOSINE PHOSPHATE REDUCTASE; INOSINATE DEHYDROGENASE; NUCLEOTIDASE; NUCLEOTIDE; PURINE; PYRIMIDINE; RIBONUCLEOTIDE REDUCTASE; URIDINE KINASE;

ARTICLE; BINDING AFFINITY; BIOCHEMISTRY; CELL METABOLISM; DRUG TARGETING; ENZYME ACTIVITY; ENZYME SPECIFICITY; ENZYME STRUCTURE; ENZYME SUBSTRATE; HUMAN; MOLECULAR MECHANICS; NUCLEOTIDE METABOLISM; PRIORITY JOURNAL; PROTEIN DOMAIN; PURINE METABOLISM; PYRIMIDINE METABOLISM; STRUCTURAL GENOMICS;

ALLOSTERIC REGULATION; HUMANS; METABOLIC NETWORKS AND PATHWAYS; NUCLEOTIDES; PHOSPHOTRANSFERASES; PROTEIN CONFORMATION; PYROPHOSPHATASES; RIBONUCLEOTIDE REDUCTASES; SUBSTRATE SPECIFICITY;

EID: 77952303898     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2010.04.054     Document Type: Article

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