Loss of CAK phosphorylation of RARα mediates transcriptional control of retinoid-induced cancer cell differentiation

FASEB Journal

Volumn 24, Issue 3, 2010, Pages 833-843

  Wang, Anxun ^a   Alimova, Irina N ^a   Luo, Peihua ^a   Jong, Ambrose ^a,b   Triche, Timothy J ^a,b   Wu, Lingtao ^a,b  

^a CHILDREN S HOSPITAL LOS ANGELES   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Cell cycle G1 exit; Decreased CAK activity by RA; Gene transcription; Transcriptional repression

Indexed keywords

CYCLIN DEPENDENT KINASE ACTIVATING KINASE; RETINOIC ACID RECEPTOR ALPHA; CYCLIN DEPENDENT KINASE; CYCLIN-DEPENDENT KINASE-ACTIVATING KINASE; RETINOIC ACID; RETINOIC ACID RECEPTOR;

AMINO ACID SUBSTITUTION; ARTICLE; CELL CYCLE G1 PHASE; CELL DIFFERENTIATION; CHROMATIN; CONTROLLED STUDY; DNA RESPONSIVE ELEMENT; EMBRYONAL CARCINOMA STEM CELL; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; MYELOID LEUKEMIA; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DNA INTERACTION; TRANSACTIVATION; TRANSCRIPTION REGULATION; ANIMAL; CELL CYCLE; CHROMATIN IMMUNOPRECIPITATION; DRUG EFFECT; GEL MOBILITY SHIFT ASSAY; GENETIC TRANSCRIPTION; GENETICS; METABOLISM; MOUSE; PHOSPHORYLATION; PHYSIOLOGY; PROTEIN BINDING; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR CELL LINE; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; CELL CYCLE; CELL DIFFERENTIATION; CELL LINE, TUMOR; CHROMATIN IMMUNOPRECIPITATION; CYCLIN-DEPENDENT KINASES; ELECTROPHORETIC MOBILITY SHIFT ASSAY; HUMANS; MICE; PHOSPHORYLATION; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; RECEPTORS, RETINOIC ACID; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRANSCRIPTION, GENETIC; TRETINOIN;

EID: 77952296807     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.09-142976     Document Type: Article

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