메뉴 건너뛰기




Volumn 1, Issue 1, 2009, Pages 87-95

Development of a LC-MS/MS method to analyze 5-methoxy-N,N- dimethyltryptamine and bufotenine: Application to pharmacokinetic study

Author keywords

[No Author keywords available]

Indexed keywords


EID: 77952291461     PISSN: 17576180     EISSN: 17576199     Source Type: Journal    
DOI: 10.4155/bio.09.7     Document Type: Article
Times cited : (21)

References (25)
  • 1
    • 53849113961 scopus 로고    scopus 로고
    • Indolealkylamines: Biotransformations and potential drug-drug interactions
    • Yu AM. Indolealkylamines: biotransformations and potential drug-drug interactions. AAPS J 10(2), 242-253 (2008).
    • (2008) AAPS J , vol.10 , Issue.2 , pp. 242-253
    • Yu, A.M.1
  • 2
    • 2942532123 scopus 로고    scopus 로고
    • Monoamine oxidase inhibitor poisoning resulting from Internet misinformation on illicit substances
    • Brush DE, Bird SB, Boyer EW. Monoamine oxidase inhibitor poisoning resulting from Internet misinformation on illicit substances. J. Toxicol. Clin. Toxicol. 42(2), 191-195 (2004).
    • (2004) J. Toxicol. Clin. Toxicol. , vol.42 , Issue.2 , pp. 191-195
    • Brush, D.E.1    Bird, S.B.2    Boyer, E.W.3
  • 3
    • 0037572153 scopus 로고    scopus 로고
    • A-methyltryptamine revisited via easy Internet access
    • Long H, Nelson LS, Hoffman RS. a-methyltryptamine revisited via easy Internet access. Vet. Hum. Toxicol. 45(3), 149 (2003).
    • (2003) Vet. Hum. Toxicol. , vol.45 , Issue.3 , pp. 149
    • Long, H.1    Nelson, L.S.2    Hoffman, R.S.3
  • 4
    • 9444228877 scopus 로고    scopus 로고
    • New drugs of abuse update: Foxy methoxy
    • Muller AA. New drugs of abuse update: foxy methoxy. J. Emerg. Nurs. 30(5), 507-508 (2004).
    • (2004) J. Emerg. Nurs. , vol.30 , Issue.5 , pp. 507-508
    • Muller, A.A.1
  • 5
    • 33645686880 scopus 로고    scopus 로고
    • Rhabdomyolysis after ingestion of "foxy, " a hallucinogenic tryptamine derivative
    • Alatrash G, Majhail NS, Pile JC. Rhabdomyolysis after ingestion of "foxy, " a hallucinogenic tryptamine derivative. Mayo Clin. Proc. 81(4), 550-551 (2006).
    • (2006) Mayo Clin. Proc. , vol.81 , Issue.4 , pp. 550-551
    • Alatrash, G.1    Majhail, N.S.2    Pile, J.C.3
  • 6
    • 29144529744 scopus 로고    scopus 로고
    • A fatal intoxication following the ingestion of 5-methoxy-N, N-dimethyltryptamine in an ayahuasca preparation
    • Sklerov J, Levine B, Moore KA, King T, Fowler D. A fatal intoxication following the ingestion of 5-methoxy-N, N-dimethyltryptamine in an ayahuasca preparation. J. Anal. Toxicol. 29(8), 838-841 (2005).
    • (2005) J. Anal. Toxicol. , vol.29 , Issue.8 , pp. 838-841
    • Sklerov, J.1    Levine, B.2    Moore, K.A.3    King, T.4    Fowler, D.5
  • 7
    • 0034769003 scopus 로고    scopus 로고
    • Pharmanopo-psychonautics: Human intranasal, sublingual, intrarectal, pulmonary and oral pharmacology of bufotenine
    • Ott J. Pharmanopo-psychonautics: human intranasal, sublingual, intrarectal, pulmonary and oral pharmacology of bufotenine. J. Psychoactive Drugs 33(3), 273-281 (2001).
    • (2001) J. Psychoactive Drugs , vol.33 , Issue.3 , pp. 273-281
    • Ott, J.1
  • 8
    • 0035686702 scopus 로고    scopus 로고
    • Pharmepena-psychonautics: Human intranasal, sublingual and oral pharmacology of 5-methoxy-N, N-dimethyl-tryptamine
    • Ott J. Pharmepena-psychonautics: human intranasal, sublingual and oral pharmacology of 5-methoxy-N, N-dimethyl-tryptamine. J. Psychoactive Drugs 33(4), 403-407 (2001).
    • (2001) J. Psychoactive Drugs , vol.33 , Issue.4 , pp. 403-407
    • Ott, J.1
  • 9
    • 2542476021 scopus 로고    scopus 로고
    • Clinical investigations of the therapeutic potential of ayahuasca: Rationale and regulatory challenges
    • McKenna DJ. Clinical investigations of the therapeutic potential of ayahuasca: rationale and regulatory challenges. Pharmacol. Ther. 102(2), 111-129 (2004).
    • (2004) Pharmacol. Ther. , vol.102 , Issue.2 , pp. 111-129
    • McKenna, D.J.1
  • 10
    • 33747684131 scopus 로고    scopus 로고
    • A demand for clarity regarding a case report on the ingestion of 5-methoxy-N, N-dimethyltryptamine (5-MeO-DMT) in an ayahuasca preparation
    • author reply 407
    • Callaway JC, Grob CS, McKenna DJ et al. A demand for clarity regarding a case report on the ingestion of 5-methoxy-N, N-dimethyltryptamine (5-MeO-DMT) in an ayahuasca preparation. J. Anal. Toxicol. 30(6), 406-407; author reply 407 (2006).
    • (2006) J. Anal. Toxicol. , vol.30 , Issue.6 , pp. 406-407
    • Callaway, J.C.1    Grob, C.S.2    McKenna, D.J.3
  • 12
    • 0038240578 scopus 로고    scopus 로고
    • Screening for endogenous substrates reveals that CYP2D6 is a 5-methoxyindolethylamine O-demethylase
    • Yu AM, Idle JR, Herraiz T, Kupfer A, Gonzalez FJ. Screening for endogenous substrates reveals that CYP2D6 is a 5-methoxyindolethylamine O-demethylase. Pharmacogenetics 13(6), 307-319 (2003).
    • (2003) Pharmacogenetics , vol.13 , Issue.6 , pp. 307-319
    • Yu, A.M.1    Idle, J.R.2    Herraiz, T.3    Kupfer, A.4    Gonzalez, F.J.5
  • 13
    • 3042515935 scopus 로고    scopus 로고
    • Polymorphic cytochrome P450 2D6: Humanized mouse model and endogenous substrates
    • Yu AM, Idle JR, Gonzalez FJ. Polymorphic cytochrome P450 2D6: humanized mouse model and endogenous substrates. Drug Metab. Rev. 36(2), 243-277 (2004).
    • (2004) Drug Metab. Rev. , vol.36 , Issue.2 , pp. 243-277
    • Yu, A.M.1    Idle, J.R.2    Gonzalez, F.J.3
  • 14
    • 0030899598 scopus 로고    scopus 로고
    • High-affnity agonist binding is not suffcient for agonist effcacy at 5-hydroxytryptamine2A receptors: Evidence in favor of a modifed ternary complex model
    • Roth BL, Choudhary MS, Khan N, Uluer AZ. High-affnity agonist binding is not suffcient for agonist effcacy at 5-hydroxytryptamine2A receptors: evidence in favor of a modifed ternary complex model. J. Pharmacol. Exp. Ther. 280(2), 576-583 (1997).
    • (1997) J. Pharmacol. Exp. Ther. , vol.280 , Issue.2 , pp. 576-583
    • Roth, B.L.1    Choudhary, M.S.2    Khan, N.3    Uluer, A.Z.4
  • 15
    • 0034232469 scopus 로고    scopus 로고
    • Bufotenine: Toward an understanding of possible psychoactive mechanisms
    • McBride MC. Bufotenine: toward an understanding of possible psychoactive mechanisms. J. Psychoactive Drugs 32(3), 321-331 (2000).
    • (2000) J. Psychoactive Drugs , vol.32 , Issue.3 , pp. 321-331
    • McBride, M.C.1
  • 16
    • 0029145545 scopus 로고
    • Tissue distribution, metabolism and effects of bufotenine administered to rats
    • Fuller RW, Snoddy HD, Perry KW. Tissue distribution, metabolism and effects of bufotenine administered to rats. Neuropharmacology 34(7), 799-804 (1995).
    • (1995) Neuropharmacology , vol.34 , Issue.7 , pp. 799-804
    • Fuller, R.W.1    Snoddy, H.D.2    Perry, K.W.3
  • 17
    • 18844458025 scopus 로고    scopus 로고
    • Potentially hallucinogenic 5-hydroxytryptamine receptor ligands bufotenine and dimethyltryptamine in blood and tissues
    • Karkkainen J, Forsstrom T, Tornaeus J et al. Potentially hallucinogenic 5-hydroxytryptamine receptor ligands bufotenine and dimethyltryptamine in blood and tissues. Scand. J. Clin. Lab. Invest. 65(3), 189-199 (2005).
    • (2005) Scand. J. Clin. Lab. Invest. , vol.65 , Issue.3 , pp. 189-199
    • Karkkainen, J.1    Forsstrom, T.2    Tornaeus, J.3
  • 18
    • 0035232091 scopus 로고    scopus 로고
    • Determination of potentially hallucinogenic N-di methylated indoleamines in human urine by HPLC/ESI-MS-MS
    • Forsstrom T, Tuominen J, Karkkainen J. Determination of potentially hallucinogenic N-di methylated indoleamines in human urine by HPLC/ESI-MS-MS. Scand. J. Clin. Lab. Invest. 61(7), 547-556 (2001).
    • (2001) Scand. J. Clin. Lab. Invest. , vol.61 , Issue.7 , pp. 547-556
    • Forsstrom, T.1    Tuominen, J.2    Karkkainen, J.3
  • 19
    • 0035835412 scopus 로고    scopus 로고
    • Distribution of the hallucinogens N, N-dimethyltryptamine and 5-methoxy-N, N-dimethyltryptamine in rat brain following intraperitoneal injection: Application of a new solid-phase extraction LC-APcI-MS-MS-isotope dilution method
    • Barker SA, Littlefeld-Chabaud MA, David C. Distribution of the hallucinogens N, N-dimethyltryptamine and 5-methoxy-N, N-dimethyltryptamine in rat brain following intraperitoneal injection: application of a new solid-phase extraction LC-APcI-MS-MS-isotope dilution method. J. Chromatogr. B Biomed. Sci. Appl. 751(1), 37-47 (2001).
    • (2001) J. Chromatogr. B Biomed. Sci. Appl. , vol.751 , Issue.1 , pp. 37-47
    • Barker, S.A.1    Littlefeld-Chabaud, M.A.2    David, C.3
  • 20
    • 37449031036 scopus 로고    scopus 로고
    • A general approach to the screening and confrmation of tryptamines and phenethylamines by mass spectral fragmentation
    • Chen BH, Liu JT, Chen WX, Chen HM, Lin CH. A general approach to the screening and confrmation of tryptamines and phenethylamines by mass spectral fragmentation. Talanta 74(4), 512-517 (2008).
    • (2008) Talanta , vol.74 , Issue.4 , pp. 512-517
    • Chen, B.H.1    Liu, J.T.2    Chen, W.X.3    Chen, H.M.4    Lin, C.H.5
  • 21
    • 0028856510 scopus 로고
    • Urinary excretion of bufotenin (N, N-dimethyl-5-hydroxytryptamine) is increased in suspicious violent offenders: A confrmatory study
    • Karkkainen J, Raisanen M, Huttunen MO et al. Urinary excretion of bufotenin (N, N-dimethyl-5-hydroxytryptamine) is increased in suspicious violent offenders: a confrmatory study. Psychiatry Res. 58 (2), 145-152 (1995).
    • (1995) Psychiatry Res. , vol.58 , Issue.2 , pp. 145-152
    • Karkkainen, J.1    Raisanen, M.2    Huttunen, M.O.3
  • 22
    • 0033970783 scopus 로고    scopus 로고
    • The paradox of 5-methoxy-N, N-dimethyltryptamine: An indoleamine hallucinogen that induces stimulus control via 5-HT1A receptors
    • Winter JC, Filipink RA, Timineri D, Helsley SE, Rabin RA. The paradox of 5-methoxy-N, N-dimethyltryptamine: an indoleamine hallucinogen that induces stimulus control via 5-HT1A receptors. Pharmacol. Biochem. Behav. 65(1), 75-82 (2000).
    • (2000) Pharmacol. Biochem. Behav. , vol.65 , Issue.1 , pp. 75-82
    • Winter, J.C.1    Filipink, R.A.2    Timineri, D.3    Helsley, S.E.4    Rabin, R.A.5
  • 23
    • 33751103938 scopus 로고    scopus 로고
    • The roles of 5-HT1A and 5-HT2 receptors in the effects of 5-MeO-DMT on locomotor activity and prepulse inhibition in rats
    • Krebs-Thomson K, Ruiz EM, Masten V, Buell M, Geyer MA. The roles of 5-HT1A and 5-HT2 receptors in the effects of 5-MeO-DMT on locomotor activity and prepulse inhibition in rats. Psychopharmacology (Berl.) 189(3), 319-329 (2006).
    • (2006) Psychopharmacology (Berl.) , vol.189 , Issue.3 , pp. 319-329
    • Krebs-Thomson, K.1    Ruiz, E.M.2    Masten, V.3    Buell, M.4    Geyer, M.A.5
  • 24
    • 33745245269 scopus 로고    scopus 로고
    • Expression, purifcation, and characterization of mouse CYP2d22
    • Yu AM, Haining RL. Expression, purifcation, and characterization of mouse CYP2d22. Drug Metab. Dispos. 34(7), 1167-1174 (2006).
    • (2006) Drug Metab. Dispos. , vol.34 , Issue.7 , pp. 1167-1174
    • Yu, A.M.1    Haining, R.L.2
  • 25
    • 0035213861 scopus 로고    scopus 로고
    • The CYP2D6 humanized mouse: Effect of the human CYP2D6 transgene and HNF4a on the disposition of debrisoquine in the mouse
    • Corchero J, Granvil CP, Akiyama TE et al. The CYP2D6 humanized mouse: effect of the human CYP2D6 transgene and HNF4a on the disposition of debrisoquine in the mouse. Mol. Pharmacol. 60(6), 1260-1267 (2001).
    • (2001) Mol. Pharmacol. , vol.60 , Issue.6 , pp. 1260-1267
    • Corchero, J.1    Granvil, C.P.2    Akiyama, T.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.