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Volumn 65, Issue 1, 2000, Pages 75-82

The paradox of 5-methoxy-N,N-dimethyltryptamine: An indoleamine hallucinogen that induces stimulus control via 5-HT(1A) receptors

Author keywords

5 HT(1A); 5 HT(2A); 5 Methoxy N,N dimethyltryptamine; Drug induced stimulus control; Rat

Indexed keywords

2 DIPROPYLAMINO 8 HYDROXYTETRALIN; 2,5 DIMETHOXY 4 METHYLAMPHETAMINE; 5 METHOXY N,N DIMETHYLTRYPTAMINE; N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; PINDOLOL; PIRENPERONE; PSYCHEDELIC AGENT; SEROTONIN 1A ANTAGONIST; SEROTONIN 1A RECEPTOR;

EID: 0033970783     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0091-3057(99)00178-1     Document Type: Article
Times cited : (62)

References (50)
  • 2
    • 0025309319 scopus 로고
    • Drug discrimination and drug stimulus generalization with anxiolytics
    • Ator N.A. Drug discrimination and drug stimulus generalization with anxiolytics. Drug Dev. Res. 20:1990;189-204.
    • (1990) Drug Dev. Res. , vol.20 , pp. 189-204
    • Ator, N.A.1
  • 3
    • 0024312012 scopus 로고
    • Asymmetrical cross-generalization in drug discrimination with lorazepam and pentobarbital training conditions
    • Ator N.A., Griffiths R.R. Asymmetrical cross-generalization in drug discrimination with lorazepam and pentobarbital training conditions. Drug Dev. Res. 16:1989;355-364.
    • (1989) Drug Dev. Res. , vol.16 , pp. 355-364
    • Ator, N.A.1    Griffiths, R.R.2
  • 4
    • 0030932023 scopus 로고    scopus 로고
    • Selectivity in the generalization profile in baboons trained to discriminate lorazepam: Benzodiazepines, barbiturates, and other sedative/anxiolytics
    • Ator N.A., Griffiths R.R. Selectivity in the generalization profile in baboons trained to discriminate lorazepam. Benzodiazepines, barbiturates, and other sedative/anxiolytics J. Pharmacol. Exp. Ther. 282:1997;1442-1457.
    • (1997) J. Pharmacol. Exp. Ther. , vol.282 , pp. 1442-1457
    • Ator, N.A.1    Griffiths, R.R.2
  • 6
    • 0016700091 scopus 로고
    • Role of serotonin in the discriminative stimulus properties of mescaline
    • Browne R.G., Ho B.T. Role of serotonin in the discriminative stimulus properties of mescaline. Pharmacol. Biochem. Behav. 3:1975;429-435.
    • (1975) Pharmacol. Biochem. Behav. , vol.3 , pp. 429-435
    • Browne, R.G.1    Ho, B.T.2
  • 7
    • 0020051801 scopus 로고
    • A drug discrimination analysis of LSD: In vivo agonist and antagonist effects of purported 5-HT antagonists and of pirenperone, a LSD-antagonist
    • Colpaert F.C., Niemegeers C.J.E., Janssen P.A.J. A drug discrimination analysis of LSD. In vivo agonist and antagonist effects of purported 5-HT antagonists and of pirenperone, a LSD-antagonist J. Pharmacol. Exp. Ther. 221:1982;206-214.
    • (1982) J. Pharmacol. Exp. Ther. , vol.221 , pp. 206-214
    • Colpaert, F.C.1    Niemegeers, C.J.E.2    Janssen, P.A.J.3
  • 8
    • 0029068288 scopus 로고
    • The time-dependent stimulus effects of 1-[2,5-dimethoxy-4-methylphenyl]-2-aminopropane [[-]-DOM]: Implications for drug-induced stimulus control as a method for the study of hallucinogenic agents
    • Fiorella D., Palumbo P.A., Rabin R.A., Winter J.C. The time-dependent stimulus effects of 1-[2,5-dimethoxy-4-methylphenyl]-2-aminopropane [[-]-DOM]. Implications for drug-induced stimulus control as a method for the study of hallucinogenic agents Psychopharmacology (Berlin). 119:1995;239-245.
    • (1995) Psychopharmacology (Berlin) , vol.119 , pp. 239-245
    • Fiorella, D.1    Palumbo, P.A.2    Rabin, R.A.3    Winter, J.C.4
  • 9
    • 0028972383 scopus 로고
    • 2C receptors in the stimulus effects of hallucinogenic drugs I: Antagonist correlation analysis
    • 2C receptors in the stimulus effects of hallucinogenic drugs I. Antagonist correlation analysis Psychopharmacology (Berlin). 121:1995;347-356.
    • (1995) Psychopharmacology (Berlin) , vol.121 , pp. 347-356
    • Fiorella, D.1    Rabin, R.A.2    Winter, J.C.3
  • 11
    • 0343751941 scopus 로고
    • Further characterization of the discriminative stimulus induced by 8-OH-DPAT in rats
    • Fozard J.R., Kidd E.J., Neill J., Tricklebank M. Further characterization of the discriminative stimulus induced by 8-OH-DPAT in rats. Br. J. Pharmacol. 88:1986;371P.
    • (1986) Br. J. Pharmacol. , vol.88
    • Fozard, J.R.1    Kidd, E.J.2    Neill, J.3    Tricklebank, M.4
  • 12
    • 0003345402 scopus 로고
    • Serotonin-LSD interaction
    • Gaddum J.H. Serotonin-LSD interaction. Ann. NY Acad. Sci. 66:1957;562-575.
    • (1957) Ann. NY Acad. Sci. , vol.66 , pp. 562-575
    • Gaddum, J.H.1
  • 15
    • 0018770993 scopus 로고
    • Hallucinogens as discriminative stimuli: Generalization of [-]-DOM to a 5-methoxy-N,N-dimethyltryptamine stimulus
    • Glennon R.A., Rosecrans J.A., Young R., Gaines J. Hallucinogens as discriminative stimuli. Generalization of [-]-DOM to a 5-methoxy-N,N-dimethyltryptamine stimulus Life Sci. 24:1979;993-998.
    • (1979) Life Sci. , vol.24 , pp. 993-998
    • Glennon, R.A.1    Rosecrans, J.A.2    Young, R.3    Gaines, J.4
  • 16
    • 0002584786 scopus 로고
    • The use of the drug discrimination paradigm for studying hallucinogenic agents
    • F.C. Colpaert, & J.L. Slangen. Amsterdam: Elsevier
    • Glennon R.A., Rosecrans J.A., Young R. The use of the drug discrimination paradigm for studying hallucinogenic agents. Colpaert F.C., Slangen J.L. Drug discrimination. Applications in CNS pharmacology:1982;69-96 Elsevier, Amsterdam.
    • (1982) Drug Discrimination: Applications in CNS Pharmacology , pp. 69-96
    • Glennon, R.A.1    Rosecrans, J.A.2    Young, R.3
  • 17
  • 19
    • 0025763213 scopus 로고
    • Multiple populations of serotonin receptors may modulate the behavioral effects of serotonergic agents
    • Glennon R.A., Darmani N.A., Martin B.R. Multiple populations of serotonin receptors may modulate the behavioral effects of serotonergic agents. Life Sci. 48:1991;2493-2498.
    • (1991) Life Sci. , vol.48 , pp. 2493-2498
    • Glennon, R.A.1    Darmani, N.A.2    Martin, B.R.3
  • 22
    • 0015184720 scopus 로고
    • Mescaline and lysergic acid diethylamide [LSD] as discriminative stimuli
    • Hirschhorn I.D., Winter J.C. Mescaline and lysergic acid diethylamide [LSD] as discriminative stimuli. Psychopharmacologia. 22:1971;64-71.
    • (1971) Psychopharmacologia , vol.22 , pp. 64-71
    • Hirschhorn, I.D.1    Winter, J.C.2
  • 23
    • 0030961840 scopus 로고    scopus 로고
    • 5-HT receptor classification and nomenclature: Towards a harmonization with the human genome
    • Hoyer D., Martin G. 5-HT receptor classification and nomenclature. Towards a harmonization with the human genome Neuropharmacology. 36:1997;419-428.
    • (1997) Neuropharmacology , vol.36 , pp. 419-428
    • Hoyer, D.1    Martin, G.2
  • 25
    • 0031594813 scopus 로고    scopus 로고
    • 2A receptors in the primate cerebral cortex: Possible site of action of hallucinogenic and antipsychotic drugs in pyramidal cell apical dendrites
    • 2A receptors in the primate cerebral cortex. Possible site of action of hallucinogenic and antipsychotic drugs in pyramidal cell apical dendrites Proc. Natl. Acad. Sci. USA. 95:1998;735-740.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 735-740
    • Jakab, R.L.1    Goldman-Rakic, P.S.2
  • 27
    • 0010479435 scopus 로고
    • Discriminative stimulus properties of hallucinogens: Behavioral assay of drug action
    • H. Lal. New York: Plenum
    • Kuhn D.M., White F.J., Appel J.B. Discriminative stimulus properties of hallucinogens. Behavioral assay of drug action Lal H. Discriminative stimulus properties of drugs. 1977;137-155 Plenum, New York.
    • (1977) Discriminative Stimulus Properties of Drugs , pp. 137-155
    • Kuhn, D.M.1    White, F.J.2    Appel, J.B.3
  • 31
    • 0026476103 scopus 로고
    • The stimulus properties of ibogaine in rats trained with yohimbine, DOM, and LSD
    • Palumbo P.A., Winter J.C. The stimulus properties of ibogaine in rats trained with yohimbine, DOM, and LSD. Pharmacol. Biochem. Behav. 43:1992;1221-1226.
    • (1992) Pharmacol. Biochem. Behav. , vol.43 , pp. 1221-1226
    • Palumbo, P.A.1    Winter, J.C.2
  • 35
    • 0028076884 scopus 로고
    • Blockade of the discriminative stimulus effects of DOI by MDL 100,907 and the atypical antipsychotics, clozapine and risperidone
    • Schreiber R., Brocco M., Millan M.J. Blockade of the discriminative stimulus effects of DOI by MDL 100,907 and the atypical antipsychotics, clozapine and risperidone. Eur. J. Pharmacol. 264:1994;99-102.
    • (1994) Eur. J. Pharmacol. , vol.264 , pp. 99-102
    • Schreiber, R.1    Brocco, M.2    Millan, M.J.3
  • 38
    • 0023601703 scopus 로고
    • Serotonin receptor subtypes mediation of the interoceptive discriminative stimuli induced by 5-methoxy-N,N-dimethyltryptamine
    • Spencer D.G., Glaser T., Traber J. Serotonin receptor subtypes mediation of the interoceptive discriminative stimuli induced by 5-methoxy-N,N-dimethyltryptamine. Psychopharmacology (Berlin). 93:1987;158-166.
    • (1987) Psychopharmacology (Berlin) , vol.93 , pp. 158-166
    • Spencer, D.G.1    Glaser, T.2    Traber, J.3
  • 39
    • 0029970119 scopus 로고    scopus 로고
    • Differential tolerance to biological and subjective effects of four closely spaced doses of N,N-dimethyltryptamine in humans
    • Strassman R.J., Qualls C.R., Berg L.M. Differential tolerance to biological and subjective effects of four closely spaced doses of N,N-dimethyltryptamine in humans. Biol. Psychiatry. 39:1996;784-795.
    • (1996) Biol. Psychiatry , vol.39 , pp. 784-795
    • Strassman, R.J.1    Qualls, C.R.2    Berg, L.M.3
  • 41
  • 42
    • 0022341312 scopus 로고
    • Subtypes of the 5-HT receptor mediating the behavioral responses to 5-methoxy-N,N-dimethyltryptamine in the rat
    • Tricklebank M.D., Forler C., Middlemiss D.N., Fozard J.R. Subtypes of the 5-HT receptor mediating the behavioral responses to 5-methoxy-N,N-dimethyltryptamine in the rat. Eur. J. Pharmacol. 117:1985;15-24.
    • (1985) Eur. J. Pharmacol. , vol.117 , pp. 15-24
    • Tricklebank, M.D.1    Forler, C.2    Middlemiss, D.N.3    Fozard, J.R.4
  • 43
    • 0016681343 scopus 로고
    • Blockade of the stimulus properties of mescaline by a serotonergic antagonist
    • Winter J.C. Blockade of the stimulus properties of mescaline by a serotonergic antagonist. Arch. Int. Pharmacodyn. 214:1975;250-253.
    • (1975) Arch. Int. Pharmacodyn. , vol.214 , pp. 250-253
    • Winter, J.C.1
  • 44
    • 0017837182 scopus 로고
    • Stimulus properties of phenethylamine hallucinogens and lysergic acid diethylamide: The role of 5-hydroxytryptamine
    • Winter J.C. Stimulus properties of phenethylamine hallucinogens and lysergic acid diethylamide. The role of 5-hydroxytryptamine J. Pharmacol. Exp. Ther. 204:1978;416-423.
    • (1978) J. Pharmacol. Exp. Ther. , vol.204 , pp. 416-423
    • Winter, J.C.1
  • 45
    • 0002305692 scopus 로고
    • Drug-induced stimulus control
    • D.E. Blackman, & D.J. Sanger. New York: Plenum
    • Winter J.C. Drug-induced stimulus control. Blackman D.E., Sanger D.J. Contemporary research in behavioral pharmacology. 1978;209-237 Plenum, New York.
    • (1978) Contemporary Research in Behavioral Pharmacology , pp. 209-237
    • Winter, J.C.1
  • 46
    • 0021337577 scopus 로고
    • The stimulus properties of p-methoxyamphetamine: A nonessential serotonergic component
    • Winter J.C. The stimulus properties of p-methoxyamphetamine. A nonessential serotonergic component Pharmacol. Biochem. Behav. 20:1984;201-203.
    • (1984) Pharmacol. Biochem. Behav. , vol.20 , pp. 201-203
    • Winter, J.C.1
  • 47
    • 0024161618 scopus 로고
    • Interactions between serotonergic agonists and antagonists in rats trained with LSD as a discriminative stimulus
    • Winter J.C., Rabin R.A. Interactions between serotonergic agonists and antagonists in rats trained with LSD as a discriminative stimulus. Pharmacol. Biochem. Behav. 30:1988;617-624.
    • (1988) Pharmacol. Biochem. Behav. , vol.30 , pp. 617-624
    • Winter, J.C.1    Rabin, R.A.2
  • 48
    • 0019192169 scopus 로고
    • Discriminative stimulus properties of the hallucinogenic agent DOM
    • Young R., Glennon R.A., Rosecrans J.A. Discriminative stimulus properties of the hallucinogenic agent DOM. Commun. Psychopharmacol. 4:1980;501-506.
    • (1980) Commun. Psychopharmacol. , vol.4 , pp. 501-506
    • Young, R.1    Glennon, R.A.2    Rosecrans, J.A.3
  • 49
    • 0019973857 scopus 로고
    • Comparative discriminative stimulus effects of 5-Methoxy-N,N-dimethyltryptamine and LSD
    • Young R., Rosecrans J.A., Glennon R.A. Comparative discriminative stimulus effects of 5-Methoxy-N,N-dimethyltryptamine and LSD. Life Sci. 30:1982;2057-2062.
    • (1982) Life Sci. , vol.30 , pp. 2057-2062
    • Young, R.1    Rosecrans, J.A.2    Glennon, R.A.3
  • 50
    • 0020646478 scopus 로고
    • Behavioral effects of 5-Methoxy-N,N-dimethyltryptamine and dose-dependent antagonism by BC-105
    • Young R., Rosecrans J.A., Glennon R.A. Behavioral effects of 5-Methoxy-N,N-dimethyltryptamine and dose-dependent antagonism by BC-105. Psychopharmacology (Berlin). 80:1983;156-160.
    • (1983) Psychopharmacology (Berlin) , vol.80 , pp. 156-160
    • Young, R.1    Rosecrans, J.A.2    Glennon, R.A.3


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