Effects of carboxylic acids on the uptake of non-transferrin-bound iron by astrocytes

Neurochemistry International

Volumn 56, Issue 6-7, 2010, Pages 843-849

  Keenan, Belinda M ^a   Robinson, Stephen R ^a   Bishop, Glenda M ^a  

^a MONASH UNIVERSITY   (Australia)

Author keywords

Citric acid; Malic acid; Neurodegeneration; NTBI; Tartaric acid

Indexed keywords

2 OXOGLUTARIC ACID; CARBOXYLIC ACID; CITRIC ACID; FUMARIC ACID; GLUTARIC ACID; IRON; MALIC ACID; NON TRANSFERRIN BOUND IRON; OXIDOREDUCTASE; PHOSPHATE; SUCCINIC ACID; TARTARIC ACID; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; ASTROCYTE; BINDING KINETICS; CELL TRANSPORT; CONTROLLED STUDY; ENZYME INHIBITION; IRON TRANSPORT; MOLECULAR MECHANICS; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; ANIMALS, NEWBORN; ASTROCYTES; BIOLOGICAL TRANSPORT; BRAIN; CARBOXYLIC ACIDS; CELLS, CULTURED; CHLORIDES; CITRIC ACID; FERRIC COMPOUNDS; IRON; MALATES; PHOSPHATES; RATS; RATS, WISTAR; TARTRATES;

RATTUS;

EID: 77952289663     PISSN: 01970186     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuint.2010.03.009     Document Type: Article

References (52)

1. Ballot D., Baynes R.D., Bothwell T.H., Gillooly M., MacFarlane B.J., MacPhail A.P., Lyons G., Derman D.P., Bezwoda W.R., Torrance J.D., et al. The effects of fruit juices and fruits on the absorption of iron from a rice meal. Br. J. Nutr. 1987, 57:331-343.
2. Bates G.W., Billups C., Saltman P. The kinetics and mechanism of iron (III) exchange between chelates and transferrin. I. The complexes of citrate and nitrilotriacetic acid. J. Biol. Chem. 1967, 242:2810-2815.
3. Benjamini Y., Hochberg Y. Controlling the false discovery rate: a powerful approach to multiple testing. J. R. Stat. Soc. B 1995, 57:289-300.
4. Bishop G.M., Robinson S.R. Quantitative analysis of cell death and ferritin expression in response to cortical iron: implications for hypoxia-ischemia and stroke. Brain Res. 2001, 907:175-187.
5. Bradbury M.W. Transport of iron in the blood-brain-cerebrospinal fluid system. J. Neurochem. 1997, 69:443-454.
6. Connor J.R., Snyder B.S., Beard J.L., Fine R.E., Mufson E.J. Regional distribution of iron and iron-regulatory proteins in the brain in aging and Alzheimer's disease. J. Neurosci. Res. 1992, 31:327-335.
7. Dexter D.T., Carayon A., Javoy-Agid F., Agid Y., Wells F.R., Daniel S.E., Lees A.J., Jenner P., Marsden C.D. Alterations in the levels of iron, ferritin and other trace metals in Parkinson's disease and other neurodegenerative diseases affecting the basal ganglia. Brain 1991, 114(Pt 4):1953-1975.
8. Dringen R., Bishop G.M., Koeppe M., Dang T.N., Robinson S.R. The pivotal role of astrocytes in the metabolism of iron in the brain. Neurochem. Res. 2007, 32:1884-1890.
9. Dringen R., Kussmaul L., Hamprecht B. Detoxification of exogenous hydrogen peroxide and organic hydroperoxides by cultured astroglial cells assessed by microtiter plate assay. Brain Res. Brain Res. Protoc. 1998, 2:223-228.
10. Garrick M.D., Kuo H.C., Vargas F., Singleton S., Zhao L., Smith J.J., Paradkar P., Roth J.A., Garrick L.M. Comparison of mammalian cell lines expressing distinct isoforms of divalent metal transporter 1 in a tetracycline-regulated fashion. Biochem. J. 2006, 398:539-546.
11. Gillooly M., Bothwell T.H., Torrance J.D., MacPhail A.P., Derman D.P., Bezwoda W.R., Mills W., Charlton R.W., Mayet F. The effects of organic acids, phytates and polyphenols on the absorption of iron from vegetables. Br. J. Nutr. 1983, 49:331-342.
12. Glahn R.P., Lai C., Hsu J., Thompson J.F., Guo M., Van Campen D.R. Decreased citrate improves iron availability from infant formula: application of an in vitro digestion/Caco-2 cell culture model. J. Nutr. 1998, 128:257-264.
13. Guerinot M.L., Meidl E.J., Plessner O. Citrate as a siderophore in Bradyrhizobium japonicum. J. Bacteriol. 1990, 172:3298-3303.
14. Gunshin H., Mackenzie B., Berger U.V., Gunshin Y., Romero M.F., Boron W.F., Nussberger S., Gollan J.L., Hediger M.A. Cloning and characterization of a mammalian proton-coupled metal-ion transporter. Nature 1997, 388:482-488.
15. Hallgren B., Sourander P. The effect of age on the non-haemin iron in the human brain. J. Neurochem. 1958, 3:41-51.
16. Halliwell B., Gutteridge J.M.C. Free Radicals in Biology and Medicine 2007, Oxford University Press, New York. 4th ed.
17. Hamprecht B., Loffler F. Primary glial cultures as a model for studying hormone action. Methods Enzymol. 1985, 109:341-345.
18. Harle C., Kim I., Angerer A., Braun V. Signal transfer through three compartments: transcription initiation of the Escherichia coli ferric citrate transport system from the cell surface. EMBO J. 1995, 14:1430-1438.
19. Heap L., Ward R.J., Abiaka C., Dexter D., Lawlor M., Pratt O., Thomson A., Shaw K., Peters T.J. The influence of brain acetaldehyde on oxidative status, dopamine metabolism and visual discrimination task. Biochem. Pharmacol. 1995, 50:263-270.
20. Hoepken H.H., Korten T., Robinson S.R., Dringen R. Iron accumulation, iron-mediated toxicity and altered levels of ferritin and transferrin receptor in cultured astrocytes during incubation with ferric ammonium citrate. J. Neurochem. 2004, 88:1194-1202.
21. Hoffmann G.F., Meier-Augenstein W., Stockler S., Surtees R., Rating D., Nyhan W.L. Physiology and pathophysiology of organic acids in cerebrospinal fluid. J. Inherit. Metab. Dis. 1993, 16:648-669.
22. Jeong S.Y., David S. Glycosylphosphatidylinositol-anchored ceruloplasmin is required for iron efflux from cells in the central nervous system. J. Biol. Chem. 2003, 278:27144-27148.
23. Ke Y., Qian Z.M. Brain iron metabolism: neurobiology and neurochemistry. Prog. Neurobiol. 2007, 83:149-173.
24. 1H NMR spectroscopy. J. Anal. Chem. 2008, 63:104-120.
25. Konigsberger L.C., Konigsberger E., May P.M., Hefter G.T. Complexation of iron(III) and iron(II) by citrate. Implications for iron speciation in blood plasma. J. Inorg. Biochem. 2000, 78:175-184.
26. Lane D.J., Lawen A. A highly sensitive colorimetric microplate ferrocyanide assay applied to ascorbate-stimulated transplasma membrane ferricyanide reduction and mitochondrial succinate oxidation. Anal. Biochem. 2008, 373:287-295.
27. Levenson C.W., Tassabehji N.M. Iron and ageing: an introduction to iron regulatory mechanisms. Ageing Res. Rev. 2004, 3:251-263.
28. Lowry O.H., Rosebrough N.J., Farr A.L., Randall R.J. Protein measurement with the Folin phenol reagent. J. Biol. Chem. 1951, 193:265-275.
29. +-coupled metal-ion transporters NRAMP1 and DMT1. Pflugers Arch. 2004, 447:571-579.
30. Martell A.E., Smith R.M. Critical Stability Constants, Vol.3, Other Organic Ligands 1977, Plenum Press, New York.
31. Michalke B., Halbach S., Berthele A., Mistriotis P., Ochsenkuhn-Petropoulou M. Size characterization of manganese species from human serum and cerebrospinal fluid using size exclusion chromatography coupled to inductively coupled mass spectrometry. J. Anal. At. Spectrom. 2007, 22:267-272.
32. Millerot-Serrurot E., Bertrand N., Mossiat C., Faure P., Prigent-Tessier A., Garnier P., Bejot Y., Giroud M., Beley A., Marie C. Temporal changes in free iron levels after brain ischemia. Relevance to the timing of iron chelation therapy in stroke. Neurochem. Int. 2008, 52:1442-1448.
33. Moos T., Morgan E.H. Evidence for low molecular weight, non-transferrin-bound iron in rat brain and cerebrospinal fluid. J. Neurosci. Res. 1998, 54:486-494.
34. Moos T., Oates P.S., Morgan E.H. Iron-independent neuronal expression of transferrin receptor mRNA in the rat. Brain Res. Mol. Brain Res. 1999, 72:231-234.
35. Peters T., Apt L., Ross J.F. Effect of phosphates upon iron absorption studied in normal human subjects and in an experimental model using dialysis. Gastroenterology 1971, 61:315-322.
36. Puntel R.L., Nogueira C.W., Rocha J.B. Krebs cycle intermediates modulate thiobarbituric acid reactive species (TBARS) production in rat brain in vitro. Neurochem. Res. 2005, 30:225-235.
37. Puntel R.L., Roos D.H., Grotto D., Garcia S.C., Nogueira C.W., Rocha J.B. Antioxidant properties of Krebs cycle intermediates against malonate pro-oxidant activity in vitro: a comparative study using the colorimetric method and HPLC analysis to determine malondialdehyde in rat brain homogenates. Life Sci. 2007, 81:51-62.
38. 3+ in solutions of phosphate, fulvate and simple carboxylate ligands. Inorg. Nucl. Chem. Lett. 1974, 10:109-114.
39. Riemer J., Hoepken H.H., Czerwinska H., Robinson S.R., Dringen R. Colorimetric ferrozine-based assay for the quantitation of iron in cultured cells. Anal. Biochem. 2004, 331:370-375.
40. Robinson S.R., Dang T.N., Dringen R., Bishop G.M. Hemin toxicity: a preventable source of brain damage following hemorrhagic stroke. Redox Rep. 2009, 14:228-235.
41. Salovaara S., Sandberg A.S., Andlid T. Organic acids influence iron uptake in the human epithelial cell line Caco-2. J. Agric. Food Chem. 2002, 50:6233-6238.
42. Salovaara S., Sandberg A.S., Andlid T. Combined impact of pH and organic acids on iron uptake by Caco-2 cells. J. Agric. Food Chem. 2003, 51:7820-7824.
43. Scheller D., Kolb J., Tegtmeier F., Lehmenkuhler A. Extracellular changes of inorganic phosphate are different during spreading depression and global cerebral ischemia of rats. Neurosci. Lett. 1992, 141:269-272.
44. 13C NMR: implications for metal coordination in biological systems. Biometals 2009, 22:771-778.
45. Smythe C.V., Schmidt C.L.A. Studies on the mode of combination of iron with certain proteins, amino acids, and related compounds. J. Biol. Chem. 1930, 88:241-269.
46. Sonnewald U., Risan A.G., Hole H.B., Westergaard N., Qu H. Citrate, beneficial or deleterious in the CNS?. Neurochem. Res. 2002, 27:155-159.
47. Takeda A., Devenyi A., Connor J.R. Evidence for non-transferrin-mediated uptake and release of iron and manganese in glial cell cultures from hypotransferrinemic mice. J. Neurosci. Res. 1998, 51:454-462.
48. Tandy S., Williams M., Leggett A., Lopez-Jimenez M., Dedes M., Ramesh B., Srai S.K., Sharp P. Nramp2 expression is associated with pH-dependent iron uptake across the apical membrane of human intestinal Caco-2 cells. J. Biol. Chem. 2000, 275:1023-1029.
49. Tulpule K., Robinson S.R., Bishop G.M., Dringen R. Uptake of ferrous iron by cultured rat astrocytes. J. Neurosci. Res. 2010, 88:563-571.
50. Wang X.S., Ong W.Y., Connor J.R. A light and electron microscopic study of the iron transporter protein DMT-1 in the monkey cerebral neocortex and hippocampus. J. Neurocytol. 2001, 30:353-360.
51. Wishart D.S., Lewis M.J., Morrissey J.A., Flegel M.D., Jeroncic K., Xiong Y., Cheng D., Eisner R., Gautam B., Tzur D., Sawhney S., Bamforth F., Greiner R., Li L. The human cerebrospinal fluid metabolome. J. Chromatogr. B: Anal. Technol. Biomed. Life Sci. 2008, 871:164-173.
52. Zhang H., Onning G., Oste R., Gramatkovski E., Hulthen L. Improved iron bioavailability in an oat-based beverage: the combined effect of citric acid addition, dephytinization and iron supplementation. Eur. J. Nutr. 2007, 46:95-102.