Insulin resistance is associated with C-reactive protein independent of abdominal obesity in nondiabetic Taiwanese

Metabolism: Clinical and Experimental

Volumn 59, Issue 6, 2010, Pages 824-830

  Chou, Hsin Hua ^a   Hsu, Lung An ^b   Liu, Chih Jen ^a   Teng, Ming Sheng ^a   Wu, Semon ^c   Ko, Yu Lin ^a,d  

^a BUDDHIST TZU CHI GENERAL HOSPITAL   (Taiwan)

^b CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

^c CHINESE CULTURE UNIVERSITY   (Taiwan)

^d TZU CHI UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

C REACTIVE PROTEIN; GLUCOSE; TRIACYLGLYCEROL;

ABDOMINAL OBESITY; ADULT; AGE; ARTICLE; BLOOD PRESSURE; CHINESE; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; FEMALE; GLUCOSE BLOOD LEVEL; HUMAN; INSULIN RESISTANCE; MAJOR CLINICAL STUDY; MALE; METABOLIC SYNDROME X; PRIORITY JOURNAL; SMOKING; TAIWAN; TRIACYLGLYCEROL BLOOD LEVEL; WAIST CIRCUMFERENCE;

ABDOMINAL FAT; ADULT; ANTHROPOMETRY; BIOLOGICAL MARKERS; C-REACTIVE PROTEIN; FEMALE; HUMANS; INSULIN RESISTANCE; LIFE STYLE; LINEAR MODELS; MALE; MIDDLE AGED; OBESITY; SEX FACTORS; TAIWAN;

EID: 77952277994     PISSN: 00260495     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.metabol.2009.09.030     Document Type: Article

References (34)

1. Liuzzo G., Biasucci L.M., Gallimore J.R., Grillo R.L., Rebuzzi A.G., Pepys M.B., et al. The prognostic value of C-reactive protein and serum amyloid a protein in severe unstable angina. N Engl J Med 331 (1994) 417-424
2. Ridker P.M., Buring J.E., Shih J., Matias M., and Hennekens C.H. Prospective study of C-reactive protein and the risk of future cardiovascular events among apparently healthy women. Circulation 98 (1998) 731-733
3. Mohamed-Ali V., Goodrick S., Rawesh A., Katz D.R., Miles J.M., Yudkin J.S., et al. Subcutaneous adipose tissue releases interleukin-6, but not tumor necrosis factor-alpha, in vivo. J Clin Endocrinol Metab 82 (1997) 4196-4200
4. Ford E.S. Body mass index, diabetes, and C-reactive protein among U.S. adults. Diabetes Care 22 (1999) 1971-1977
5. Visser M., Bouter L.M., McQuillan G.M., Wener M.H., and Harris T.B. Elevated C-reactive protein levels in overweight and obese adults. JAMA 282 (1999) 2131-2135
6. Reaven G.M. Banting lecture 1988. Role of insulin resistance in human disease. Diabetes 37 (1988) 1595-1607
7. Jeppesen J., Hansen T.W., Rasmussen S., Ibsen H., Torp-Pedersen C., and Madsbad S. Insulin resistance, the metabolic syndrome, and risk of incident cardiovascular disease: a population-based study. J Am Coll Cardiol 49 (2007) 2112-2119
8. Tenenbaum A., Adler Y., Boyko V., Tenenbaum H., Fisman E.Z., Tanne D., et al. Insulin resistance is associated with increased risk of major cardiovascular events in patients with preexisting coronary artery disease. Am Heart J 153 (2007) 559-565
9. Festa A., D'Agostino Jr. R., Howard G., Mykkanen L., Tracy R.P., and Haffner S.M. Chronic subclinical inflammation as part of the insulin resistance syndrome: the Insulin Resistance Atherosclerosis Study (IRAS). Circulation 102 (2000) 42-47
10. McLaughlin T., Abbasi F., Lamendola C., Liang L., Reaven G., Schaff P., et al. Differentiation between obesity and insulin resistance in the association with C-reactive protein. Circulation 106 (2002) 2908-2912
11. Nakanishi N., Shiraishi T., and Wada M. Association between C-reactive protein and insulin resistance in a Japanese population: the Minoh Study. Intern Med 44 (2005) 542-547
12. Pradhan A.D., Cook N.R., Buring J.E., Manson J.E., and Ridker P.M. C-reactive protein is independently associated with fasting insulin in nondiabetic women. Arterioscler Thromb Vasc Biol 23 (2003) 650-655
13. Niehoff A.G., van Haeften T.W., Onland-Moret N.C., Elbers C.C., Wijmenga C., and van der Schouw Y.T. C-reactive protein is independently associated with glucose but not with insulin resistance in healthy men. Diabetes Care 30 (2007) 1627-1629
14. Hak A.E., Stehouwer C.D., Bots M.L., Polderman K.H., Schalkwijk C.G., Westendorp I.C., et al. Associations of C-reactive protein with measures of obesity, insulin resistance, and subclinical atherosclerosis in healthy, middle-aged women. Arterioscler Thromb Vasc Biol 19 (1999) 1986-1991
15. Forouhi N.G., Sattar N., and McKeigue P.M. Relation of C-reactive protein to body fat distribution and features of the metabolic syndrome in Europeans and South Asians. Int J Obes Relat Metab Disord 25 (2001) 1327-1331
16. Temelkova-Kurktschiev T., Siegert G., Bergmann S., Henkel E., Koehler C., Jaross W., et al. Subclinical inflammation is strongly related to insulin resistance but not to impaired insulin secretion in a high risk population for diabetes. Metabolism 51 (2002) 743-749
17. Despres J.P. Abdominal obesity as important component of insulin-resistance syndrome. Nutrition 9 (1993) 452-459
18. Karter A.J., Mayer-Davis E.J., Selby J.V., D'Agostino Jr. R.B., Haffner S.M., Sholinsky P., et al. Insulin sensitivity and abdominal obesity in African-American, Hispanic, and non-Hispanic white men and women. The Insulin Resistance and Atherosclerosis Study. Diabetes 45 (1996) 1547-1555
19. Kohrt W.M., Kirwan J.P., Staten M.A., Bourey R.E., King D.S., and Holloszy J.O. Insulin resistance in aging is related to abdominal obesity. Diabetes 42 (1993) 273-281
20. Anand S.S., Razak F., Yi Q., Davis B., Jacobs R., Vuksan V., et al. C-reactive protein as a screening test for cardiovascular risk in a multiethnic population. Arterioscler Thromb Vasc Biol 24 (2004) 1509-1515
21. Kelley-Hedgepeth A., Lloyd-Jones D.M., Colvin A., Matthews K.A., Johnston J., Sowers M.R., et al. Ethnic differences in C-reactive protein concentrations. Clin Chem 54 (2008) 1027-1037
22. Lear S.A., Chen M.M., Birmingham C.L., and Frohlich J.J. The relationship between simple anthropometric indices and C-reactive protein: ethnic and gender differences. Metabolism 52 (2003) 1542-1546
23. Tan C.E., Ma S., Wai D., Chew S.K., and Tai E.S. Can we apply the National Cholesterol Education Program Adult Treatment Panel definition of the metabolic syndrome to Asians?. Diabetes Care 27 (2004) 1182-1186
24. Wu T.L., Tsao K.C., Chang C.P., Li C.N., Sun C.F., and Wu J.T. Development of ELISA on microplate for serum C-reactive protein and establishment of age-dependent normal reference range. Clin Chim Acta 322 (2002) 163-168
25. Hotamisligil G.S., Shargill N.S., and Spiegelman B.M. Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance. Science 259 (1993) 87-91
26. Kern P.A., Ranganathan S., Li C., Wood L., and Ranganathan G. Adipose tissue tumor necrosis factor and interleukin-6 expression in human obesity and insulin resistance. Am J Physiol Endocrinol Metab 280 (2001) E745-E751
27. Hotamisligil G.S., Budavari A., Murray D., and Spiegelman B.M. Reduced tyrosine kinase activity of the insulin receptor in obesity-diabetes. Central role of tumor necrosis factor-alpha. J Clin Invest 94 (1994) 1543-1549
28. Senn J.J., Klover P.J., Nowak I.A., and Mooney R.A. Interleukin-6 induces cellular insulin resistance in hepatocytes. Diabetes 51 (2002) 3391-3399
29. Heinrich P.C., Castell J.V., and Andus T. Interleukin-6 and the acute phase response. Biochem J 265 (1990) 621-636
30. Aljada A., Ghanim H., Mohanty P., Kapur N., and Dandona P. Insulin inhibits the pro-inflammatory transcription factor early growth response gene-1 (Egr-1) expression in mononuclear cells (MNC) and reduces plasma tissue factor (TF) and plasminogen activator inhibitor-1 (PAI-1) concentrations. J Clin Endocrinol Metab 87 (2002) 1419-1422
31. Dandona P., Aljada A., Mohanty P., Ghanim H., Hamouda W., Assian E., et al. Insulin inhibits intranuclear nuclear factor kappaB and stimulates IkappaB in mononuclear cells in obese subjects: evidence for an anti-inflammatory effect?. J Clin Endocrinol Metab 86 (2001) 3257-3265
32. Kathiresan S., Larson M.G., Vasan R.S., Gua C.Y., Gona P., Keaney J.F., et al. Contribution of clinical correlates and 13 C-reactive protein gene polymorphisms to interindividual variability in serum C-reactive protein level. Circulation 113 (2006) 1415-1423
33. Teng M.S., Hsu L.A., Wu S., Chang H.H., Chou H.H., and Ko Y.L. Association between C-reactive protein gene haplotypes and C-reactive protein levels in Taiwanese: interaction with obesity. Atherosclerosis 204 (2009) e64-69
34. Li L.M., Lei S.F., Chen X.D., Deng F.Y., Tan L.J., Zhu X.Z., et al. Anthropometric indices as the predictors of trunk obesity in Chinese young adults: receiver operating characteristic analyses. Ann Hum Biol 35 (2008) 342-348