-
1
-
-
0000454838
-
Insulin resistance: the fundamental trigger of type 2 diabetes
-
Groop L.C. Insulin resistance: the fundamental trigger of type 2 diabetes. Diabetes Obes Metab 1 Suppl 1 (1999) S1-S7
-
(1999)
Diabetes Obes Metab
, vol.1
, Issue.SUPPL. 1
-
-
Groop, L.C.1
-
2
-
-
0027762766
-
Insulin resistance and insulin secretory dysfunction as precursors of non-insulin-dependent diabetes mellitus. Prospective studies of Pima Indians
-
Lillioja S., Mott D.M., Spraul M., et al. Insulin resistance and insulin secretory dysfunction as precursors of non-insulin-dependent diabetes mellitus. Prospective studies of Pima Indians. N Engl J Med 329 (1993) 1988-1992
-
(1993)
N Engl J Med
, vol.329
, pp. 1988-1992
-
-
Lillioja, S.1
Mott, D.M.2
Spraul, M.3
-
3
-
-
0026793446
-
Role of glucose and insulin resistance in development of type 2 diabetes mellitus: results of a 25-year follow-up study
-
Martin B.C., Warram J.H., Krolewski A.S., et al. Role of glucose and insulin resistance in development of type 2 diabetes mellitus: results of a 25-year follow-up study. Lancet 340 (1992) 925-929
-
(1992)
Lancet
, vol.340
, pp. 925-929
-
-
Martin, B.C.1
Warram, J.H.2
Krolewski, A.S.3
-
4
-
-
14644390267
-
Insulin sensitivity at diagnosis of type 2 diabetes is not associated with subsequent cardiovascular disease (UKPDS 67)
-
Adler A.I., Levy J.C., Matthews D.R., et al. Insulin sensitivity at diagnosis of type 2 diabetes is not associated with subsequent cardiovascular disease (UKPDS 67). Diabet Med 22 (2005) 306-311
-
(2005)
Diabet Med
, vol.22
, pp. 306-311
-
-
Adler, A.I.1
Levy, J.C.2
Matthews, D.R.3
-
5
-
-
0037882913
-
Strong Heart Study. Insulin resistance, the metabolic syndrome, and risk of incident cardiovascular disease in nondiabetic American Indians: the Strong Heart Study
-
Resnick H.E., Jones K., Ruotolo G., et al. Strong Heart Study. Insulin resistance, the metabolic syndrome, and risk of incident cardiovascular disease in nondiabetic American Indians: the Strong Heart Study. Diabetes Care 26 (2003) 861-867
-
(2003)
Diabetes Care
, vol.26
, pp. 861-867
-
-
Resnick, H.E.1
Jones, K.2
Ruotolo, G.3
-
6
-
-
0028139059
-
Hyperinsulinemia does not increase the risk of fatal cardiovascular disease in elderly men or women without diabetes: the Rancho Bernardo Study, 1984-1991
-
Ferrara A., Barrett-Connor E.L., and Edelstein S.L. Hyperinsulinemia does not increase the risk of fatal cardiovascular disease in elderly men or women without diabetes: the Rancho Bernardo Study, 1984-1991. Am J Epidemiol 140 (1994) 857-869
-
(1994)
Am J Epidemiol
, vol.140
, pp. 857-869
-
-
Ferrara, A.1
Barrett-Connor, E.L.2
Edelstein, S.L.3
-
7
-
-
0026728956
-
Hyperinsulinaemia is not a major coronary risk factor in elderly men. The study of men born in 1913
-
Welin L., Eriksson H., Larsson B., et al. Hyperinsulinaemia is not a major coronary risk factor in elderly men. The study of men born in 1913. Diabetologia 35 (1992) 766-770
-
(1992)
Diabetologia
, vol.35
, pp. 766-770
-
-
Welin, L.1
Eriksson, H.2
Larsson, B.3
-
8
-
-
0035660210
-
Lack of association of insulin resistance and carotid intimal medial thickness in nondiabetic Asian Indian subjects
-
Snehalatha C., Vijay V., Suresh Mohan R., et al. Lack of association of insulin resistance and carotid intimal medial thickness in nondiabetic Asian Indian subjects. Diabetes Metab Res Rev 17 (2001) 444-447
-
(2001)
Diabetes Metab Res Rev
, vol.17
, pp. 444-447
-
-
Snehalatha, C.1
Vijay, V.2
Suresh Mohan, R.3
-
9
-
-
20044368678
-
Insulin sensitivity, proinsulin and insulin as predictors of coronary heart disease. A population-based 10-year, follow-up study in 70-year old men using the euglycaemic insulin clamp
-
Zethelius B., Lithell H., Hales C.N., et al. Insulin sensitivity, proinsulin and insulin as predictors of coronary heart disease. A population-based 10-year, follow-up study in 70-year old men using the euglycaemic insulin clamp. Diabetologia 48 (2005) 862-867
-
(2005)
Diabetologia
, vol.48
, pp. 862-867
-
-
Zethelius, B.1
Lithell, H.2
Hales, C.N.3
-
10
-
-
0345698971
-
Hyperinsulinemia predicts coronary heart disease risk in healthy middle-aged men: the 22-year follow-up results of the Helsinki Policemen Study
-
Pyorala M., Miettinen H., Laakso M., et al. Hyperinsulinemia predicts coronary heart disease risk in healthy middle-aged men: the 22-year follow-up results of the Helsinki Policemen Study. Circulation 98 (1998) 398-404
-
(1998)
Circulation
, vol.98
, pp. 398-404
-
-
Pyorala, M.1
Miettinen, H.2
Laakso, M.3
-
11
-
-
2542507751
-
Insulin resistance syndrome predicts coronary heart disease events in elderly nondiabetic men
-
Lempiainen P., Mykkanen L., Pyorala K., et al. Insulin resistance syndrome predicts coronary heart disease events in elderly nondiabetic men. Circulation 100 (1999) 123-128
-
(1999)
Circulation
, vol.100
, pp. 123-128
-
-
Lempiainen, P.1
Mykkanen, L.2
Pyorala, K.3
-
12
-
-
0029862973
-
Hyperinsulinemia as an independent risk factor for ischemic heart disease
-
Despres J.P., Lamarche B., Mauriege P., et al. Hyperinsulinemia as an independent risk factor for ischemic heart disease. N Engl J Med 334 (1996) 952-957
-
(1996)
N Engl J Med
, vol.334
, pp. 952-957
-
-
Despres, J.P.1
Lamarche, B.2
Mauriege, P.3
-
13
-
-
0037322198
-
Hyperinsulinaemia as long-term predictor of death and ischaemic heart disease in nondiabetic men: the Malmo Preventive Project
-
Nilsson P., Nilsson J.A., Hedblad B., et al. Hyperinsulinaemia as long-term predictor of death and ischaemic heart disease in nondiabetic men: the Malmo Preventive Project. J Intern Med 253 (2003) 136-145
-
(2003)
J Intern Med
, vol.253
, pp. 136-145
-
-
Nilsson, P.1
Nilsson, J.A.2
Hedblad, B.3
-
14
-
-
30744460648
-
Insulin resistance, the metabolic syndrome, and incident cardiovascular events in the Framingham Offspring Study
-
Rutter M.K., Meigs J.B., Sullivan L.M., et al. Insulin resistance, the metabolic syndrome, and incident cardiovascular events in the Framingham Offspring Study. Diabetes 54 (2005) 3252-3257
-
(2005)
Diabetes
, vol.54
, pp. 3252-3257
-
-
Rutter, M.K.1
Meigs, J.B.2
Sullivan, L.M.3
-
15
-
-
20244370323
-
Rationale and design of a secondary prevention trial of increasing serum high-density lipoprotein cholesterol and reducing triglycerides in patients with clinically manifest atherosclerotic heart disease (the Bezafibrate Infarction Prevention Trial)
-
Goldbourt U., Behar S., Reicher-Reiss H., et al. Rationale and design of a secondary prevention trial of increasing serum high-density lipoprotein cholesterol and reducing triglycerides in patients with clinically manifest atherosclerotic heart disease (the Bezafibrate Infarction Prevention Trial). Am J Cardiol 71 (1993) 909-915
-
(1993)
Am J Cardiol
, vol.71
, pp. 909-915
-
-
Goldbourt, U.1
Behar, S.2
Reicher-Reiss, H.3
-
16
-
-
0034604225
-
Secondary prevention by raising HDL cholesterol and reducing triglycerides in patients with coronary artery disease: the Bezafibrate Infarction Prevention (BIP) study
-
Secondary prevention by raising HDL cholesterol and reducing triglycerides in patients with coronary artery disease: the Bezafibrate Infarction Prevention (BIP) study. Circulation 102 (2000) 21-27
-
(2000)
Circulation
, vol.102
, pp. 21-27
-
-
-
17
-
-
26444604923
-
Effect of bezafibrate on incidence of type 2 diabetes mellitus in obese patients
-
Tenenbaum A., Motro M., Fisman E.Z., et al. Effect of bezafibrate on incidence of type 2 diabetes mellitus in obese patients. Eur Heart J 26 (2005) 2032-2038
-
(2005)
Eur Heart J
, vol.26
, pp. 2032-2038
-
-
Tenenbaum, A.1
Motro, M.2
Fisman, E.Z.3
-
18
-
-
1842334456
-
Report of the expert committees on the diagnosis and classification of diabetes mellitus
-
American Diabetes Association. Report of the expert committees on the diagnosis and classification of diabetes mellitus. Diabetes Care 20 (1997) 1183-1197
-
(1997)
Diabetes Care
, vol.20
, pp. 1183-1197
-
-
American Diabetes Association1
-
19
-
-
2442660528
-
Peroxisome proliferator-activated receptors ligand bezafibrate for prevention of type 2 diabetes mellitus in patients with coronary artery disease
-
Tenenbaum A., Motro M., Fisman E.Z., et al. Peroxisome proliferator-activated receptors ligand bezafibrate for prevention of type 2 diabetes mellitus in patients with coronary artery disease. Circulation 109 (2004) 2197-2202
-
(2004)
Circulation
, vol.109
, pp. 2197-2202
-
-
Tenenbaum, A.1
Motro, M.2
Fisman, E.Z.3
-
21
-
-
0942298680
-
Insulin resistance and fasting hyperinsulinemia are risk factors for new cardiovascular events in patients with prior coronary artery disease and normal glucose tolerance
-
Yanase M., Takatsu F., Tagawa T., et al. Insulin resistance and fasting hyperinsulinemia are risk factors for new cardiovascular events in patients with prior coronary artery disease and normal glucose tolerance. Circ J 68 (2004) 47-52
-
(2004)
Circ J
, vol.68
, pp. 47-52
-
-
Yanase, M.1
Takatsu, F.2
Tagawa, T.3
-
22
-
-
2542475544
-
Insulin resistance, impaired early insulin response, and insulin propeptides as predictors of the development of type 2 diabetes: a population-based, 7-year follow-up study in 70-year-old men
-
Zethelius B., Hales C.N., Lithell H.O., et al. Insulin resistance, impaired early insulin response, and insulin propeptides as predictors of the development of type 2 diabetes: a population-based, 7-year follow-up study in 70-year-old men. Diabetes Care 27 (2004) 1433-1438
-
(2004)
Diabetes Care
, vol.27
, pp. 1433-1438
-
-
Zethelius, B.1
Hales, C.N.2
Lithell, H.O.3
-
23
-
-
0033533596
-
Diabetes and cardiovascular disease. A statement for healthcare professionals from the American Heart Association
-
Grundy S.M., Benjamin I.J., Burke G.L., et al. Diabetes and cardiovascular disease. A statement for healthcare professionals from the American Heart Association. Circulation 100 (1999) 1134-1146
-
(1999)
Circulation
, vol.100
, pp. 1134-1146
-
-
Grundy, S.M.1
Benjamin, I.J.2
Burke, G.L.3
-
24
-
-
0036637538
-
Homeostasis model assessment of insulin resistance in relation to the incidence of cardiovascular disease: the San Antonio Heart study
-
Hanley A.J., Williams K., Stern M.P., et al. Homeostasis model assessment of insulin resistance in relation to the incidence of cardiovascular disease: the San Antonio Heart study. Diabetes Care 25 (2002) 1177-1184
-
(2002)
Diabetes Care
, vol.25
, pp. 1177-1184
-
-
Hanley, A.J.1
Williams, K.2
Stern, M.P.3
-
25
-
-
1542513468
-
Correlation between cardiovascular disease and diabetes mellitus: current concepts
-
Nesto R.W. Correlation between cardiovascular disease and diabetes mellitus: current concepts. Am J Med 116 Suppl 5A (2004) 11S-22S
-
(2004)
Am J Med
, vol.116
, Issue.SUPPL. 5A
-
-
Nesto, R.W.1
-
26
-
-
0027512732
-
Role of insulin resistance in human disease (syndrome X): an expanded definition
-
Reaven G.M. Role of insulin resistance in human disease (syndrome X): an expanded definition. Annu Rev Med 44 (1993) 121-131
-
(1993)
Annu Rev Med
, vol.44
, pp. 121-131
-
-
Reaven, G.M.1
-
27
-
-
10344259100
-
Insulin resistance as a contributor to myocardial ischaemia independent of obstructive coronary atheroma: a role for insulin sensitisation?
-
Jadhav S., Petrie J., Ferrell W., et al. Insulin resistance as a contributor to myocardial ischaemia independent of obstructive coronary atheroma: a role for insulin sensitisation?. Heart 90 (2004) 1379-1383
-
(2004)
Heart
, vol.90
, pp. 1379-1383
-
-
Jadhav, S.1
Petrie, J.2
Ferrell, W.3
-
28
-
-
0033983242
-
Insulin action is associated with endothelial function in hypertension and type 2 diabetes
-
Cleland S.J., Petrie J.R., Small M., et al. Insulin action is associated with endothelial function in hypertension and type 2 diabetes. Hypertension 35 (2000) 507-511
-
(2000)
Hypertension
, vol.35
, pp. 507-511
-
-
Cleland, S.J.1
Petrie, J.R.2
Small, M.3
-
29
-
-
4644318535
-
Macrovascular complications of metabolic syndrome: an early intervention is imperative
-
Tenenbaum A., Motro M., Schwammenthal E., et al. Macrovascular complications of metabolic syndrome: an early intervention is imperative. Int J Cardiol 97 (2004) 167-172
-
(2004)
Int J Cardiol
, vol.97
, pp. 167-172
-
-
Tenenbaum, A.1
Motro, M.2
Schwammenthal, E.3
-
30
-
-
0023232216
-
Helsinki Heart Study: primary-prevention trial with gemfibrozil in middle-aged men with dyslipidemia. Safety of treatment, changes in risk factors, and incidence of coronary heart disease
-
Frick M.H., Elo O., Haapa K., et al. Helsinki Heart Study: primary-prevention trial with gemfibrozil in middle-aged men with dyslipidemia. Safety of treatment, changes in risk factors, and incidence of coronary heart disease. N Engl J Med 317 (1987) 1237-1245
-
(1987)
N Engl J Med
, vol.317
, pp. 1237-1245
-
-
Frick, M.H.1
Elo, O.2
Haapa, K.3
-
31
-
-
0033527030
-
Gemfibrozil for the secondary prevention of coronary heart disease in men with low levels of high-density lipoprotein cholesterol. Veterans Affairs High-Density Lipoprotein Cholesterol Intervention Trial Study Group
-
Rubins H.B., Robins S.J., Collins D., et al. Gemfibrozil for the secondary prevention of coronary heart disease in men with low levels of high-density lipoprotein cholesterol. Veterans Affairs High-Density Lipoprotein Cholesterol Intervention Trial Study Group. N Engl J Med 341 (1999) 410-418
-
(1999)
N Engl J Med
, vol.341
, pp. 410-418
-
-
Rubins, H.B.1
Robins, S.J.2
Collins, D.3
-
32
-
-
19344375593
-
Bezafibrate for the secondary prevention of myocardial infarction in patients with metabolic syndrome
-
Tenenbaum A., Motro M., Fisman E.Z., et al. Bezafibrate for the secondary prevention of myocardial infarction in patients with metabolic syndrome. Arch Intern Med 165 (2005) 1154-1160
-
(2005)
Arch Intern Med
, vol.165
, pp. 1154-1160
-
-
Tenenbaum, A.1
Motro, M.2
Fisman, E.Z.3
-
33
-
-
26244453309
-
PROactive investigators. Secondary prevention of macrovascular events in patients with type 2 diabetes in the PROactive Study (PROspective pioglitAzone Clinical Trial In macroVascular Events): a randomised controlled trial
-
Dormandy J.A., Charbonnel B., Eckland D.J., et al. PROactive investigators. Secondary prevention of macrovascular events in patients with type 2 diabetes in the PROactive Study (PROspective pioglitAzone Clinical Trial In macroVascular Events): a randomised controlled trial. Lancet 366 (2005) 1279-1289
-
(2005)
Lancet
, vol.366
, pp. 1279-1289
-
-
Dormandy, J.A.1
Charbonnel, B.2
Eckland, D.J.3
-
34
-
-
28044452217
-
Effects of long-term fenofibrate therapy on cardiovascular events in 9795 people with type 2 diabetes mellitus (the FIELD study): randomised controlled trial
-
Keech A., Simes R.J., Barter P., et al. Effects of long-term fenofibrate therapy on cardiovascular events in 9795 people with type 2 diabetes mellitus (the FIELD study): randomised controlled trial. Lancet 366 (2005) 1849-1861
-
(2005)
Lancet
, vol.366
, pp. 1849-1861
-
-
Keech, A.1
Simes, R.J.2
Barter, P.3
-
35
-
-
0018520840
-
Glucose clamp technique: a method for quantifying insulin secretion and resistance
-
DeFronzo R.A., Tobin J.D., and Andres R. Glucose clamp technique: a method for quantifying insulin secretion and resistance. Am J Physiol 237 (1979) E214-E223
-
(1979)
Am J Physiol
, vol.237
-
-
DeFronzo, R.A.1
Tobin, J.D.2
Andres, R.3
-
36
-
-
0030994947
-
The homeostasis model in the San Antonio Heart Study
-
Haffner S.M., Miettinen H., and Stern M.P. The homeostasis model in the San Antonio Heart Study. Diabetes Care 20 (1997) 1087-1092
-
(1997)
Diabetes Care
, vol.20
, pp. 1087-1092
-
-
Haffner, S.M.1
Miettinen, H.2
Stern, M.P.3
-
37
-
-
0035095052
-
Diagnosing insulin resistance in the general population
-
McAuley K.A., Williams S.M., Mann J.I., et al. Diagnosing insulin resistance in the general population. Diabetes Care 24 (2001) 460-464
-
(2001)
Diabetes Care
, vol.24
, pp. 460-464
-
-
McAuley, K.A.1
Williams, S.M.2
Mann, J.I.3
-
38
-
-
0035081231
-
Clinical significance of the insulin resistance index as assessed by homeostasis model assessment
-
Ikeda Y., Suehiro T., Nakamura T., et al. Clinical significance of the insulin resistance index as assessed by homeostasis model assessment. Endocr J 48 (2001) 81-86
-
(2001)
Endocr J
, vol.48
, pp. 81-86
-
-
Ikeda, Y.1
Suehiro, T.2
Nakamura, T.3
-
39
-
-
0032511566
-
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34)
-
UK Prospective Diabetes Study (UKPDS) Group
-
UK Prospective Diabetes Study (UKPDS) Group. Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). Lancet 352 (1998) 854-865
-
(1998)
Lancet
, vol.352
, pp. 854-865
-
-
-
40
-
-
33645738300
-
Attenuation of progression of insulin resistance in patients with coronary artery disease by bezafibrate
-
Tenenbaum A., Fisman E.Z., Boyko V., et al. Attenuation of progression of insulin resistance in patients with coronary artery disease by bezafibrate. Arch Intern Med 166 (2006) 737-741
-
(2006)
Arch Intern Med
, vol.166
, pp. 737-741
-
-
Tenenbaum, A.1
Fisman, E.Z.2
Boyko, V.3
-
41
-
-
19944433634
-
Rosiglitazone improves insulin sensitivity and glucose tolerance in subjects with impaired glucose tolerance
-
Hung Y.J., Hsieh C.H., Pei D., et al. Rosiglitazone improves insulin sensitivity and glucose tolerance in subjects with impaired glucose tolerance. Clin Endocrinol (Oxf) 62 (2005) 85-91
-
(2005)
Clin Endocrinol (Oxf)
, vol.62
, pp. 85-91
-
-
Hung, Y.J.1
Hsieh, C.H.2
Pei, D.3
-
42
-
-
17444420663
-
Pioglitazone improves insulin sensitivity through reduction in muscle lipid and redistribution of lipid into adipose tissue
-
Rasouli N., Raue U., Miles L.M., et al. Pioglitazone improves insulin sensitivity through reduction in muscle lipid and redistribution of lipid into adipose tissue. Am J Physiol Endocrinol Metab 288 (2005) E930-E934
-
(2005)
Am J Physiol Endocrinol Metab
, vol.288
-
-
Rasouli, N.1
Raue, U.2
Miles, L.M.3
|