-
1
-
-
67650385302
-
-
Atlanta, GA: American Cancer Society, Inc; 2009
-
Cancer Facts and Figures 2009. Atlanta, GA: American Cancer Society, Inc; 2009.
-
(2009)
Cancer Facts and Figures
-
-
-
2
-
-
0027240519
-
Identification of the von Hippel-Lindau disease tumor suppressor gene
-
F Latif K Tory J Gnarra, et al. 1993 Identification of the von Hippel-Lindau disease tumor suppressor gene Science 260 1317 1320 10.1126/science.8493574 1:CAS:528:DyaK3sXks12htbc%3D 8493574 (Pubitemid 23231974)
-
(1993)
Science
, vol.260
, Issue.5112
, pp. 1317-1320
-
-
Latif, F.1
Tory, K.2
Gnarra, J.3
Yao, M.4
Duh, F.-M.5
Orcutt, M.L.6
Stackhouse, T.7
Kuzmin, I.8
Modi, W.9
Geil, L.10
Schmidt, L.11
Zhou, F.12
Li, H.13
Ming Hui Wei14
Chen, F.15
Glenn, G.16
Choyke, P.17
Walther, M.M.18
Weng, Y.19
-
3
-
-
0027954044
-
Mutations of the VHL tumour suppressor gene in renal carcinoma
-
DOI 10.1038/ng0594-85
-
JR Gnarra K Tory Y Weng, et al. 1994 Mutations of the VHL tumour suppressor gene in renal carcinoma Nat Genet 7 85 90 10.1038/ng0594-85 1:CAS:528:DyaK2cXktlaitbg%3D 7915601 (Pubitemid 24232386)
-
(1994)
Nature Genetics
, vol.7
, Issue.1
, pp. 85-90
-
-
Gnarra, J.R.1
Tory, K.2
Weng, Y.3
Schmidt, L.4
Wei, M.H.5
Li, H.6
Latif, F.7
Liu, S.8
Chen, F.9
Duh, F.-M.10
Lubensky, I.11
Duan, D.R.12
Florence, C.13
Pozzatti, R.14
Walther, M.M.15
Bander, N.H.16
Grossman, H.B.17
Brauch, H.18
Pomer, S.19
Brooks, J.D.20
Isaacs, W.B.21
Lerman, M.I.22
Zbar, B.23
Linehan, W.M.24
more..
-
4
-
-
0028235907
-
Frequent somatic mutations and loss of heterozygosity of the von Hippel-Lindau tumor suppressor gene in primary human renal cell carcinomas
-
1:CAS:528:DyaK2cXksl2rsLo%3D 8187067
-
T Shuin K Kondo S Torigoe, et al. 1994 Frequent somatic mutations and loss of heterozygosity of the von Hippel-Lindau tumor suppressor gene in primary human renal cell carcinomas Cancer Res 54 2852 2855 1:CAS:528: DyaK2cXksl2rsLo%3D 8187067
-
(1994)
Cancer Res
, vol.54
, pp. 2852-2855
-
-
Shuin, T.1
Kondo, K.2
Torigoe, S.3
-
5
-
-
0033587146
-
The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis
-
DOI 10.1038/20459
-
PH Maxwell MS Wiesener GW Chang, et al. 1999 The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis Nature 399 271 275 10.1038/20459 1:CAS:528:DyaK1MXjsFyqt74%3D 10353251 (Pubitemid 29246458)
-
(1999)
Nature
, vol.399
, Issue.6733
, pp. 271-275
-
-
Maxwell, P.H.1
Wlesener, M.S.2
Chang, G.-W.3
Clifford, S.C.4
Vaux, E.C.5
Cockman, M.E.6
Wykoff, C.C.7
Pugh, C.W.8
Maher, E.R.9
Ratcliffe, P.J.10
-
6
-
-
0037837724
-
Multiple splice variants of the human HIF-3α locus are targets of the von Hippel-Lindau E3 ubiquitin ligase complex
-
DOI 10.1074/jbc.M208681200
-
MA Maynard H Qi J Chung, et al. 2003 Multiple splice variants of the human HIF-3 alpha locus are targets of the von Hippel-Lindau E3 ubiquitin ligase complex J Biol Chem 278 11032 11040 10.1074/jbc.M208681200 1:CAS:528: DC%2BD3sXit1Kgsro%3D 12538644 (Pubitemid 36792653)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.13
, pp. 11032-11040
-
-
Maynard, M.A.1
Qi, H.2
Chung, J.3
Lee, E.H.L.4
Kondo, Y.5
Hara, S.6
Conaway, R.C.7
Conaway, J.W.8
Ohh, M.9
-
7
-
-
0036528246
-
Inhibition of HIF is necessary for tumor suppression by the von Hippel-Lindau protein
-
DOI 10.1016/S1535-6108(02)00043-0
-
K Kondo J Klco E Nakamura, et al. 2002 Inhibition of HIF is necessary for tumor suppression by the von Hippel-Lindau protein Cancer Cell 1 237 246 10.1016/S1535-6108(02)00043-0 1:CAS:528:DC%2BD38XjsFGltrY%3D 12086860 (Pubitemid 41039148)
-
(2002)
Cancer Cell
, vol.1
, Issue.3
, pp. 237-246
-
-
Kondo, K.1
Klco, J.2
Nakamura, E.3
Lechpammer, M.4
Kaelin Jr., W.G.5
-
8
-
-
0029090338
-
Tumour suppression by the human von Hippel-Lindau gene product
-
10.1038/nm0895-822 1:CAS:528:DyaK2MXnt1ynu7c%3D 7585187
-
O Iliopoulos A Kibel S Gray, et al. 1995 Tumour suppression by the human von Hippel-Lindau gene product Nat Med 1 822 826 10.1038/nm0895-822 1:CAS:528:DyaK2MXnt1ynu7c%3D 7585187
-
(1995)
Nat Med
, vol.1
, pp. 822-826
-
-
Iliopoulos, O.1
Kibel, A.2
Gray, S.3
-
9
-
-
60349101704
-
VHL gene mutations in renal cell carcinoma: Role as a biomarker of disease outcome and drug efficacy
-
10.1007/s11912-009-0015-5 1:CAS:528:DC%2BD1MXltVSluro%3D 19216840
-
CL Cowey WK Rathmell 2009 VHL gene mutations in renal cell carcinoma: role as a biomarker of disease outcome and drug efficacy Curr Oncol Rep 11 94 101 10.1007/s11912-009-0015-5 1:CAS:528:DC%2BD1MXltVSluro%3D 19216840
-
(2009)
Curr Oncol Rep
, vol.11
, pp. 94-101
-
-
Cowey, C.L.1
Rathmell, W.K.2
-
10
-
-
33846199233
-
Hypoxia-inducible factors: Central regulators of the tumor phenotype
-
DOI 10.1016/j.gde.2006.12.006, PII S0959437X06002401, Genetic and Cellular mechanisms of oncogenesis
-
JD Gordan MC Simon 2007 Hypoxia-inducible factors: central regulators of the tumor phenotype Curr Opin Genet Dev 17 71 77 10.1016/j.gde.2006.12.006 1:CAS:528:DC%2BD2sXnslOntw%3D%3D 17208433 (Pubitemid 46109295)
-
(2007)
Current Opinion in Genetics and Development
, vol.17
, Issue.1
, pp. 71-77
-
-
Gordan, J.D.1
Simon, M.C.2
-
11
-
-
0032949884
-
Serum concentrations of VEGF and b-FGF in renal cell, prostate and urinary bladder carcinomas
-
1:STN:280:DyaK1M3jt1Wmtg%3D%3D 10216508
-
M Edgren B Lennernas A Larsson, et al. 1999 Serum concentrations of VEGF and b-FGF in renal cell, prostate and urinary bladder carcinomas Anticancer Res 19 869 873 1:STN:280:DyaK1M3jt1Wmtg%3D%3D 10216508
-
(1999)
Anticancer Res
, vol.19
, pp. 869-873
-
-
Edgren, M.1
Lennernas, B.2
Larsson, A.3
-
12
-
-
0027104066
-
Vascular permeability factor (vascular endothelial growth factor) gene is expressed differentially in normal tissues, macrophages, and tumors
-
1:CAS:528:DyaK38XitFajsL4%3D 1550962
-
B Berse LF Brown L Van de Water, et al. 1992 Vascular permeability factor (vascular endothelial growth factor) gene is expressed differentially in normal tissues, macrophages, and tumors Mol Biol Cell 3 211 220 1:CAS:528: DyaK38XitFajsL4%3D 1550962
-
(1992)
Mol Biol Cell
, vol.3
, pp. 211-220
-
-
Berse, B.1
Brown, L.F.2
Van De Water, L.3
-
13
-
-
41149091197
-
Using molecular biology to develop drugs for renal cell carcinoma
-
DOI 10.1517/17460441.3.3.311
-
CL Cowey WK Rathmell 2008 Using molecular biology to develop drugs for renal cell carcinoma Expert Opin Drug Discov 3 311 327 10.1517/17460441.3.3.311 1:CAS:528:DC%2BD1cXks1Ciurs%3D (Pubitemid 351425375)
-
(2008)
Expert Opinion on Drug Discovery
, vol.3
, Issue.3
, pp. 311-327
-
-
Cowey, C.L.1
Rathmell, W.K.2
-
14
-
-
64949107042
-
VHL type 2B gene mutation moderates HIF dosage in vitro and in vivo
-
10.1038/onc.2009.12 1:CAS:528:DC%2BD1MXisVOrur4%3D 19252526
-
CM Lee MM Hickey CA Sanford, et al. 2009 VHL type 2B gene mutation moderates HIF dosage in vitro and in vivo Oncogene 28 1694 1705 10.1038/onc.2009.12 1:CAS:528:DC%2BD1MXisVOrur4%3D 19252526
-
(2009)
Oncogene
, vol.28
, pp. 1694-1705
-
-
Lee, C.M.1
Hickey, M.M.2
Sanford, C.A.3
-
15
-
-
9244228551
-
In vitro and in vivo models analyzing von Hippel-Lindau disease-specific mutations
-
DOI 10.1158/0008-5472.CAN-04-1430
-
WK Rathmell MM Hickey NA Bezman, et al. 2004 In vitro and in vivo models analyzing von Hippel-Lindau disease-specific mutations Cancer Res 64 8595 8603 10.1158/0008-5472.CAN-04-1430 1:CAS:528:DC%2BD2cXhtVCjs73O 15574766 (Pubitemid 39552072)
-
(2004)
Cancer Research
, vol.64
, Issue.23
, pp. 8595-8603
-
-
Rathmell, W.K.1
Hickey, M.M.2
Bezman, N.A.3
Chmielecki, C.A.4
Carraway, N.C.5
Simon, M.C.6
-
16
-
-
56849096837
-
HIF-alpha effects on c-Myc distinguish two subtypes of sporadic VHL-deficient clear cell renal carcinoma
-
•• In this article, 160 ccRCC tumors were analyzed for VHL genotype and HIF-α expression. Wild-type VHL tumors and HIF1/HIF2-overexpressing tumors have increased AKT/mTOR and ERK/MAPK signaling, while HIF2-only overexpressing tumors have increased c-Myc
-
•• Gordan JD, Lal P, Dondeti VR, et al.: HIF-alpha effects on c-Myc distinguish two subtypes of sporadic VHL-deficient clear cell renal carcinoma. Cancer Cell 2008,14:435-446. In this article, 160 ccRCC tumors were analyzed for VHL genotype and HIF-α expression. Wild-type VHL tumors and HIF1/HIF2-overexpressing tumors have increased AKT/mTOR and ERK/MAPK signaling, while HIF2-only overexpressing tumors have increased c-Myc.
-
(2008)
Cancer Cell
, vol.14
, pp. 435-446
-
-
Gordan, J.D.1
Lal, P.2
Dondeti, V.R.3
-
17
-
-
75149188170
-
Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes
-
•• This article details resequencing of 3544 genes in 96 ccRCC tumors, with follow-up sequencing of 60 genes in 246 additional ccRCCs. Genes most mutated involved histone modification and DNA damage repair
-
•• Dalgliesh GL, Furge K, Greenman C, et al.: Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes. Nature 2010, 463:360-363. This article details resequencing of 3544 genes in 96 ccRCC tumors, with follow-up sequencing of 60 genes in 246 additional ccRCCs. Genes most mutated involved histone modification and DNA damage repair.
-
(2010)
Nature
, vol.463
, pp. 360-363
-
-
Dalgliesh, G.L.1
Furge, K.2
Greenman, C.3
-
18
-
-
3042667856
-
Robust classification of renal cell carcinoma based on gene expression data and predicted cytogenetic profiles
-
DOI 10.1158/0008-5472.CAN-04-0534
-
KA Furge KA Lucas M Takahashi, et al. 2004 Robust classification of renal cell carcinoma based on gene expression data and predicted cytogenetic profiles Cancer Res 64 4117 4121 10.1158/0008-5472.CAN-04-0534 1:CAS:528: DC%2BD2cXkvFWls78%3D 15205321 (Pubitemid 38802413)
-
(2004)
Cancer Research
, vol.64
, Issue.12
, pp. 4117-4121
-
-
Furge, K.A.1
Lucas, K.A.2
Takahashi, M.3
Sugimura, J.4
Kort, E.J.5
Kanayama, H.-O.6
Kagawa, S.7
Hoekstra, P.8
Curry, J.9
Yang, X.J.10
Teh, B.T.11
-
19
-
-
19944430072
-
Gene expression in kidney cancer is associated with cytogenetic abnormalities, metastasis formation, and patient survival
-
15701852
-
H Sultmann A von Heydebreck W Huber, et al. 2005 Gene expression in kidney cancer is associated with cytogenetic abnormalities, metastasis formation, and patient survival Clin Cancer Res 11 646 655 15701852
-
(2005)
Clin Cancer Res
, vol.11
, pp. 646-655
-
-
Sultmann, H.1
Von Heydebreck, A.2
Huber, W.3
-
21
-
-
66349100709
-
Patterns of gene expression and copy-number alterations in von-Hippel Lindau disease-associated and sporadic clear cell carcinoma of the kidney
-
• This is an SNP analysis and gene expression analysis of 54 sporadic and 36 VHL disease-associated ccRCC tumors. These two types of ccRCC are very similar, but sporadic tumors are more heterogeneous and contain more genotypic changes
-
• Beroukhim R, Brunet JP, Di Napoli A, et al.: Patterns of gene expression and copy-number alterations in von-Hippel Lindau disease-associated and sporadic clear cell carcinoma of the kidney. Cancer Res 2009, 69:4674-4681. This is an SNP analysis and gene expression analysis of 54 sporadic and 36 VHL disease-associated ccRCC tumors. These two types of ccRCC are very similar, but sporadic tumors are more heterogeneous and contain more genotypic changes.
-
(2009)
Cancer Res
, vol.69
, pp. 4674-4681
-
-
Beroukhim, R.1
Brunet, J.P.2
Di Napoli, A.3
-
22
-
-
59949102663
-
Cytogenetic profile predicts prognosis of patients with clear cell renal cell carcinoma
-
•• This is a prospective study of cytogenetic abnormalities in 282 sporadic ccRCC patients, identifying the retention of 3p and loss of 4p, 9p, and 14q to be associated with poor survival. Loss of 9p was incorporated into a UISS-modified nomogram
-
•• Klatte T, Rao PN, de Martino M, et al.: Cytogenetic profile predicts prognosis of patients with clear cell renal cell carcinoma. J Clin Oncol 2009, 27:746-753. This is a prospective study of cytogenetic abnormalities in 282 sporadic ccRCC patients, identifying the retention of 3p and loss of 4p, 9p, and 14q to be associated with poor survival. Loss of 9p was incorporated into a UISS-modified nomogram.
-
(2009)
J Clin Oncol
, vol.27
, pp. 746-753
-
-
Klatte, T.1
Rao, P.N.2
De Martino, M.3
-
23
-
-
67650468207
-
Genomic predictors of outcome and treatment response in breast cancer
-
1:CAS:528:DC%2BD1MXpvFehtrs%3D 19537843
-
L Dunn A Demichele 2009 Genomic predictors of outcome and treatment response in breast cancer Mol Diagn Ther 13 73 90 1:CAS:528:DC%2BD1MXpvFehtrs%3D 19537843
-
(2009)
Mol Diagn Ther
, vol.13
, pp. 73-90
-
-
Dunn, L.1
Demichele, A.2
-
24
-
-
0035859883
-
Gene expression profiling of clear cell renal cell carcinoma: Gene identification and prognostic classification
-
DOI 10.1073/pnas.171209998
-
M Takahashi DR Rhodes KA Furge, et al. 2001 Gene expression profiling of clear cell renal cell carcinoma: gene identification and prognostic classification Proc Natl Acad Sci U S A 98 9754 9759 10.1073/pnas.171209998 1:CAS:528:DC%2BD3MXmtlCms74%3D 11493696 (Pubitemid 32769376)
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, Issue.17
, pp. 9754-9759
-
-
Takahashi, M.1
Rhodes, D.R.2
Furge, K.A.3
Kanayama, H.-O.4
Kagawa, S.5
Haab, B.B.6
Teh, B.T.7
-
25
-
-
0037795737
-
Predicting survival in patients with metastatic kidney cancer by gene-expression profiling in the primary tumor
-
DOI 10.1073/pnas.1131754100
-
JR Vasselli JH Shih SR Iyengar, et al. 2003 Predicting survival in patients with metastatic kidney cancer by gene-expression profiling in the primary tumor Proc Natl Acad Sci U S A 100 6958 6963 10.1073/pnas.1131754100 1:CAS:528:DC%2BD3sXkslOntL8%3D 12777628 (Pubitemid 36706375)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.12
, pp. 6958-6963
-
-
Vasselli, J.R.1
Shih, J.H.2
Iyengar, S.R.3
Maranchie, J.4
Riss, J.5
Worrell, R.6
Torres-Cabala, C.7
Tabios, R.8
Mariotti, A.9
Stearman, R.10
Merino, M.11
Walther, M.M.12
Simon, R.13
Klausner, R.D.14
Linehan, W.M.15
-
26
-
-
33846219941
-
Vascular cell adhesion molecule 1 predicts cancer-free survival in clear cell renal carcinoma patients
-
DOI 10.1158/1078-0432.CCR-06-1737
-
K Shioi A Komiya K Hattori, et al. 2006 Vascular cell adhesion molecule 1 predicts cancer-free survival in clear cell renal carcinoma patients Clin Cancer Res 12 7339 7346 10.1158/1078-0432.CCR-06-1737 1:CAS:528: DC%2BD28XhtlCrtr%2FN 17189405 (Pubitemid 46095406)
-
(2006)
Clinical Cancer Research
, vol.12
, Issue.24
, pp. 7339-7346
-
-
Shioi, K.-I.1
Komiya, A.2
Hattori, K.3
Huang, Y.4
Sano, F.5
Murakami, T.6
Nakaigawa, N.7
Kishida, T.8
Kubota, Y.9
Nagashima, Y.10
Yao, M.11
-
27
-
-
47249164780
-
A three-gene expression signature model to predict clinical outcome of clear cell renal carcinoma
-
10.1002/ijc.23641 1:CAS:528:DC%2BD1cXhtVSrsLjF 18546273
-
M Yao Y Huang K Shioi, et al. 2008 A three-gene expression signature model to predict clinical outcome of clear cell renal carcinoma Int J Cancer 123 1126 1132 10.1002/ijc.23641 1:CAS:528:DC%2BD1cXhtVSrsLjF 18546273
-
(2008)
Int J Cancer
, vol.123
, pp. 1126-1132
-
-
Yao, M.1
Huang, Y.2
Shioi, K.3
-
28
-
-
23844524767
-
Gene signatures of progression and metastasis in renal cell cancer
-
DOI 10.1158/1078-0432.CCR-04-2225
-
J Jones H Otu D Spentzos, et al. 2005 Gene signatures of progression and metastasis in renal cell cancer Clin Cancer Res 11 5730 5739 10.1158/1078-0432.CCR-04-2225 1:CAS:528:DC%2BD2MXos1Cjsbs%3D 16115910 (Pubitemid 41170297)
-
(2005)
Clinical Cancer Research
, vol.11
, Issue.16
, pp. 5730-5739
-
-
Jones, J.1
Otu, H.2
Spentzos, D.3
Kolia, S.4
Inan, M.5
Beecken, W.D.6
Fellbaum, C.7
Gu, X.8
Joseph, M.9
Pantuck, A.J.10
Jonas, D.11
Libermann, T.A.12
-
29
-
-
22344432541
-
Clear cell renal cell carcinoma: Gene expression analyses identify a potential signature for tumor aggressiveness
-
DOI 10.1158/1078-0432.CCR-05-0073
-
F Kosari AS Parker DM Kube, et al. 2005 Clear cell renal cell carcinoma: gene expression analyses identify a potential signature for tumor aggressiveness Clin Cancer Res 11 5128 5139 10.1158/1078-0432.CCR-05-0073 1:CAS:528: DC%2BD2MXmt12qtb8%3D 16033827 (Pubitemid 41003697)
-
(2005)
Clinical Cancer Research
, vol.11
, Issue.14
, pp. 5128-5139
-
-
Kosari, F.1
Parker, A.S.2
Kube, D.M.3
Lohse, C.M.4
Leibovich, B.C.5
Blute, M.L.6
Cheville, J.C.7
Vasmatzis, G.8
-
30
-
-
33745316516
-
High expression levels of survivin protein independently predict a poor outcome for patients who undergo surgery for clear cell renal cell carcinoma
-
DOI 10.1002/cncr.21952
-
AS Parker F Kosari CM Lohse, et al. 2006 High expression levels of survivin protein independently predict a poor outcome for patients who undergo surgery for clear cell renal cell carcinoma Cancer 107 37 45 10.1002/cncr.21952 1:CAS:528:DC%2BD28XntVymtbk%3D 16736510 (Pubitemid 43939028)
-
(2006)
Cancer
, vol.107
, Issue.1
, pp. 37-45
-
-
Parker, A.S.1
Kosari, F.2
Lohse, C.M.3
Thompson, R.H.4
Kwon, E.D.5
Murphy, L.6
Riehle, D.L.7
Blute, M.L.8
Leibovich, B.C.9
Vasmatzis, G.10
Cheville, J.C.11
-
31
-
-
65649097342
-
Development and evaluation of BioScore: A biomarker panel to enhance prognostic algorithms for clear cell renal cell carcinoma
-
10.1002/cncr.24263 19296514
-
AS Parker BC Leibovich CM Lohse, et al. 2009 Development and evaluation of BioScore: a biomarker panel to enhance prognostic algorithms for clear cell renal cell carcinoma Cancer 115 2092 2103 10.1002/cncr.24263 19296514
-
(2009)
Cancer
, vol.115
, pp. 2092-2103
-
-
Parker, A.S.1
Leibovich, B.C.2
Lohse, C.M.3
-
32
-
-
32144434202
-
Gene expression profiling predicts survival in conventional renal cell carcinoma
-
• This is a gene expression microarray analysis of 177 tumors, delineating two primary and five subclusters of ccRCC
-
• Zhao H, Ljungberg B, Grankvist K, et al.: Gene expression profiling predicts survival in conventional renal cell carcinoma. PLoS Med 2006, 3:e13. This is a gene expression microarray analysis of 177 tumors, delineating two primary and five subclusters of ccRCC.
-
(2006)
PLoS Med
, vol.3
-
-
Zhao, H.1
Ljungberg, B.2
Grankvist, K.3
-
33
-
-
67649506345
-
Alteration of gene expression signatures of cortical differentiation and wound response in lethal clear cell renal cell carcinomas
-
10.1371/journal.pone.0006039 19557179
-
H Zhao M Zongming R Tibshirani, et al. 2009 Alteration of gene expression signatures of cortical differentiation and wound response in lethal clear cell renal cell carcinomas PLoS One 4 e6039 10.1371/journal.pone.0006039 19557179
-
(2009)
PLoS One
, vol.4
, pp. 6039
-
-
Zhao, H.1
Zongming, M.2
Tibshirani, R.3
-
34
-
-
39649084890
-
Molecular markers for predicting prognosis of renal cell carcinoma
-
1:CAS:528:DC%2BD1cXivVygsbw%3D 18312928
-
M Nogueira HL Kim 2008 Molecular markers for predicting prognosis of renal cell carcinoma Urol Oncol 26 113 124 1:CAS:528:DC%2BD1cXivVygsbw%3D 18312928
-
(2008)
Urol Oncol
, vol.26
, pp. 113-124
-
-
Nogueira, M.1
Kim, H.L.2
-
35
-
-
33646344690
-
Differential gene expression identifies subgroups of renal cell carcinoma
-
DOI 10.1016/j.lab.2006.04.001, PII S0022214306001387
-
KM Skubitz W Zimmermann R Kammerer, et al. 2006 Differential gene expression identifies subgroups of renal cell carcinoma J Lab Clin Med 147 250 267 10.1016/j.lab.2006.04.001 1:CAS:528:DC%2BD28Xks1Wrurc%3D 16697773 (Pubitemid 43668482)
-
(2006)
Journal of Laboratory and Clinical Medicine
, vol.147
, Issue.5
, pp. 250-267
-
-
Skubitz, K.M.1
Zimmerman, W.2
Kammerer, R.3
Pambuccian, S.4
Skubitz, A.P.N.5
-
36
-
-
77952238828
-
Molecular stratification of clear cell renal cell carcinoma by consensus clustering reveals distinct subtypes and survival patterns
-
Brannon AR, Reddy A, Seiler M, et al.: Molecular stratification of clear cell renal cell carcinoma by consensus clustering reveals distinct subtypes and survival patterns. Genes and Cancer 2010, 1:152-163.
-
(2010)
Genes and Cancer
, vol.1
, pp. 152-163
-
-
Brannon, A.R.1
Reddy, A.2
Seiler, M.3
-
37
-
-
74949115627
-
Mining tissue microarray data to uncover combinations of biomarker expression patterns that improve intermediate staging and grading of clear cell renal cell cancer
-
10.1158/1078-0432.CCR-09-0260 1:CAS:528:DC%2BC3cXot1Wl 20028743
-
C Dahinden B Ingold P Wild, et al. 2010 Mining tissue microarray data to uncover combinations of biomarker expression patterns that improve intermediate staging and grading of clear cell renal cell cancer Clin Cancer Res 16 88 98 10.1158/1078-0432.CCR-09-0260 1:CAS:528:DC%2BC3cXot1Wl 20028743
-
(2010)
Clin Cancer Res
, vol.16
, pp. 88-98
-
-
Dahinden, C.1
Ingold, B.2
Wild, P.3
-
38
-
-
70649112122
-
Identification of TNF-alpha and MMP-9 as potential baseline predictive serum markers of sunitinib activity in patients with renal cell carcinoma using a human cytokine array
-
10.1038/sj.bjc.6605409 1:CAS:528:DC%2BD1MXhsVOhtLjK 19904265
-
JL Perez-Gracia C Prior F Guillen-Grima, et al. 2009 Identification of TNF-alpha and MMP-9 as potential baseline predictive serum markers of sunitinib activity in patients with renal cell carcinoma using a human cytokine array Br J Cancer 101 1876 1883 10.1038/sj.bjc.6605409 1:CAS:528:DC%2BD1MXhsVOhtLjK 19904265
-
(2009)
Br J Cancer
, vol.101
, pp. 1876-1883
-
-
Perez-Gracia, J.L.1
Prior, C.2
Guillen-Grima, F.3
-
39
-
-
49249087039
-
Antitumor activity and biomarker analysis of sunitinib in patients with bevacizumab-refractory metastatic renal cell carcinoma
-
10.1200/JCO.2007.15.5416 1:CAS:528:DC%2BD1cXhtVGjs73L 18669461
-
BI Rini MD Michaelson JE Rosenberg, et al. 2008 Antitumor activity and biomarker analysis of sunitinib in patients with bevacizumab-refractory metastatic renal cell carcinoma J Clin Oncol 26 3743 3748 10.1200/JCO.2007.15. 5416 1:CAS:528:DC%2BD1cXhtVGjs73L 18669461
-
(2008)
J Clin Oncol
, vol.26
, pp. 3743-3748
-
-
Rini, B.I.1
Michaelson, M.D.2
Rosenberg, J.E.3
-
40
-
-
34547779489
-
Circulating protein biomarkers of pharmacodynamic activity of sunitinib in patients with metastatic renal cell carcinoma: Modulation of VEGF and VEGF-related proteins
-
DOI 10.1186/1479-5876-5-32
-
SE Deprimo CL Bello J Smeraglia, et al. 2007 Circulating protein biomarkers of pharmacodynamic activity of sunitinib in patients with metastatic renal cell carcinoma: modulation of VEGF and VEGF-related proteins J Transl Med 5 32 10.1186/1479-5876-5-32 17605814 (Pubitemid 47226331)
-
(2007)
Journal of Translational Medicine
, vol.5
, pp. 32
-
-
DePrimo, S.E.1
Bello, C.L.2
Smeraglia, J.3
Baum, C.M.4
Spinella, D.5
Rini, B.I.6
Dror, M.D.7
Motzer, R.J.8
-
41
-
-
57149115765
-
Genome-wide microRNA expression profiling in renal cell carcinoma: Significant down-regulation of miR-141 and miR-200c
-
10.1002/path.2437 1:CAS:528:DC%2BD1MXlvVWrtw%3D%3D 18925646
-
C Nakada K Matsuura Y Tsukamoto, et al. 2008 Genome-wide microRNA expression profiling in renal cell carcinoma: significant down-regulation of miR-141 and miR-200c J Pathol 216 418 427 10.1002/path.2437 1:CAS:528: DC%2BD1MXlvVWrtw%3D%3D 18925646
-
(2008)
J Pathol
, vol.216
, pp. 418-427
-
-
Nakada, C.1
Matsuura, K.2
Tsukamoto, Y.3
-
42
-
-
72649084669
-
Differential expression profiling of microRNAs and their potential involvement in renal cell carcinoma pathogenesis
-
10.1016/j.clinbiochem.2009.07.020 19646430
-
TF Chow YM Youssef E Lianidou, et al. 2009 Differential expression profiling of microRNAs and their potential involvement in renal cell carcinoma pathogenesis Clin Biochem 43 150 158 10.1016/j.clinbiochem.2009.07.020 19646430
-
(2009)
Clin Biochem
, vol.43
, pp. 150-158
-
-
Chow, T.F.1
Youssef, Y.M.2
Lianidou, E.3
-
43
-
-
77952241237
-
Identification of a microRNA panel for clear-cell kidney cancer
-
Dec 24 (Epub ahead of print)
-
Juan D, Alexe G, Antes T, et al.: Identification of a microRNA panel for clear-cell kidney cancer. Urology 2009 Dec 24 (Epub ahead of print).
-
(2009)
Urology
-
-
Juan, D.1
Alexe, G.2
Antes, T.3
-
44
-
-
67649417863
-
MicroRNA profiling of human kidney cancer subtypes
-
10.3892/ijo-00000318 1:CAS:528:DC%2BD1MXosFSlsr8%3D 19513557
-
D Petillo EJ Kort J Anema, et al. 2009 MicroRNA profiling of human kidney cancer subtypes Int J Oncol 35 109 114 10.3892/ijo-00000318 1:CAS:528:DC%2BD1MXosFSlsr8%3D 19513557
-
(2009)
Int J Oncol
, vol.35
, pp. 109-114
-
-
Petillo, D.1
Kort, E.J.2
Anema, J.3
-
45
-
-
70450247016
-
Von Hippel-Lindau gene product modulates TIS11B expression in renal cell carcinoma: Impact on vascular endothelial growth factor expression in hypoxia
-
10.1074/jbc.M109.058065 1:CAS:528:DC%2BD1MXhsVSmur3M 19801654
-
S Sinha S Dutta K Datta, et al. 2009 Von Hippel-Lindau gene product modulates TIS11B expression in renal cell carcinoma: impact on vascular endothelial growth factor expression in hypoxia J Biol Chem 284 32610 32618 10.1074/jbc.M109.058065 1:CAS:528:DC%2BD1MXhsVSmur3M 19801654
-
(2009)
J Biol Chem
, vol.284
, pp. 32610-32618
-
-
Sinha, S.1
Dutta, S.2
Datta, K.3
-
46
-
-
34249303745
-
TNM staging system for renal-cell carcinoma: Current status and future perspectives
-
DOI 10.1016/S1470-2045(07)70173-0, PII S1470204507701730
-
V Ficarra A Galfano M Mancini, et al. 2007 TNM staging system for renal-cell carcinoma: current status and future perspectives Lancet Oncol 8 554 558 10.1016/S1470-2045(07)70173-0 17540307 (Pubitemid 46805912)
-
(2007)
Lancet Oncology
, vol.8
, Issue.6
, pp. 554-558
-
-
Ficarra, V.1
Galfano, A.2
Mancini, M.3
Martignoni, G.4
Artibani, W.5
-
47
-
-
0035868654
-
Improved prognostication of renal cell carcinoma using an integrated staging system
-
A Zisman AJ Pantuck F Dorey, et al. 2001 Improved prognostication of renal cell carcinoma using an integrated staging system J Clin Oncol 19 1649 1657 1:STN:280:DC%2BD3M3gsl2gtA%3D%3D 11250993 (Pubitemid 32230864)
-
(2001)
Journal of Clinical Oncology
, vol.19
, Issue.6
, pp. 1649-1657
-
-
Zisman, A.1
Pantuck, A.J.2
Dorey, F.3
Said, J.W.4
Shvarts, O.5
Quintana, D.6
Gitlitz, B.J.7
DeKernion, J.B.8
Figlin, R.A.9
Belldegrun, A.S.10
-
48
-
-
0034966994
-
A postoperative prognostic nomogram for renal cell carcinoma
-
10.1016/S0022-5347(05)66077-6 1:STN:280:DC%2BD3MznslGitg%3D%3D 11435824
-
MW Kattan V Reuter RJ Motzer, et al. 2001 A postoperative prognostic nomogram for renal cell carcinoma J Urol 166 63 67 10.1016/S0022-5347(05)66077-6 1:STN:280:DC%2BD3MznslGitg%3D%3D 11435824
-
(2001)
J Urol
, vol.166
, pp. 63-67
-
-
Kattan, M.W.1
Reuter, V.2
Motzer, R.J.3
-
49
-
-
0036893892
-
An outcome prediction model for patients with clear cell renal cell carcinoma treated with radical nephrectomy based on tumor stage, size, grade and necrosis: The SSIGN score
-
10.1016/S0022-5347(05)64153-5 12441925
-
I Frank ML Blute JC Cheville, et al. 2002 An outcome prediction model for patients with clear cell renal cell carcinoma treated with radical nephrectomy based on tumor stage, size, grade and necrosis: the SSIGN score J Urol 168 2395 2400 10.1016/S0022-5347(05)64153-5 12441925
-
(2002)
J Urol
, vol.168
, pp. 2395-2400
-
-
Frank, I.1
Blute, M.L.2
Cheville, J.C.3
-
50
-
-
10344224583
-
A postoperative prognostic nomogram predicting recurrence for patients with conventional clear cell renal cell carcinoma
-
15592023
-
M Sorbellini MW Kattan ME Snyder, et al. 2005 A postoperative prognostic nomogram predicting recurrence for patients with conventional clear cell renal cell carcinoma J Urol 173 48 51 15592023
-
(2005)
J Urol
, vol.173
, pp. 48-51
-
-
Sorbellini, M.1
Kattan, M.W.2
Snyder, M.E.3
-
51
-
-
0032772880
-
Survival and prognostic stratification of 670 patients with advanced renal cell carcinoma
-
RJ Motzer M Mazumdar J Bacik, et al. 1999 Survival and prognostic stratification of 670 patients with advanced renal cell carcinoma J Clin Oncol 17 2530 2540 1:STN:280:DC%2BD3c%2FjtVSnug%3D%3D 10561319 (Pubitemid 29368255)
-
(1999)
Journal of Clinical Oncology
, vol.17
, Issue.8
, pp. 2530-2540
-
-
Motzer, R.J.1
Mazumdar, M.2
Bacik, J.3
Berg, W.4
Amsterdam, A.5
Ferrara, J.6
-
52
-
-
14144252047
-
Validation and extension of the Memorial Sloan-Kettering prognostic factors model for survival in patients with previously untreated metastatic renal cell carcinoma
-
DOI 10.1200/JCO.2005.05.179
-
TM Mekhail RM Abou-Jawde G Boumerhi, et al. 2005 Validation and extension of the Memorial Sloan-Kettering prognostic factors model for survival in patients with previously untreated metastatic renal cell carcinoma J Clin Oncol 23 832 841 10.1200/JCO.2005.05.179 15681528 (Pubitemid 46224183)
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.4
, pp. 832-841
-
-
Mekhail, T.M.1
Abou-Jawde, R.M.2
BouMerhi, G.3
Malhi, S.4
Wood, L.5
Elson, P.6
Bukowski, R.7
-
53
-
-
27544461925
-
A scoring algorithm to predict survival for patients with metastatic clear cell renal cell carcinoma: A stratification tool for prospective clinical trials
-
DOI 10.1097/01.ju.0000177487.64651.3a
-
BC Leibovich JC Cheville CM Lohse, et al. 2005 A scoring algorithm to predict survival for patients with metastatic clear cell renal cell carcinoma: a stratification tool for prospective clinical trials J Urol 174 1759 1763 10.1097/01.ju.0000177487.64651.3a 16217278 discussion 1763 (Pubitemid 41546928)
-
(2005)
Journal of Urology
, vol.174
, Issue.5
, pp. 1759-1763
-
-
Leibovich, B.C.1
Cheville, J.C.2
Lohse, C.M.3
Zincke, H.4
Frank, I.5
Kwon, E.D.6
Merchan, J.R.7
Blute, M.L.8
-
54
-
-
67649742301
-
Predicting cancer-control outcomes in patients with renal cell carcinoma
-
• This review clearly summarizes pre-nephrectomy and post-nephrectomy nomograms for recurrence, as well as survival prediction algorithms for nonmetastatic and metastatic disease
-
• Isbarn H, Karakiewicz PI: Predicting cancer-control outcomes in patients with renal cell carcinoma. Curr Opin Urol 2009, 19:247-257. This review clearly summarizes pre-nephrectomy and post-nephrectomy nomograms for recurrence, as well as survival prediction algorithms for nonmetastatic and metastatic disease.
-
(2009)
Curr Opin Urol
, vol.19
, pp. 247-257
-
-
Isbarn, H.1
Karakiewicz, P.I.2
-
55
-
-
20244386849
-
Using tumor markers to predict the survival of patients with metastatic renal cell carcinoma
-
DOI 10.1097/01.ju.0000154351.37249.f0
-
HL Kim D Seligson X Liu, et al. 2005 Using tumor markers to predict the survival of patients with metastatic renal cell carcinoma J Urol 173 1496 1501 10.1097/01.ju.0000154351.37249.f0 1:CAS:528:DC%2BD2MXjtFalsrk%3D 15821467 (Pubitemid 40524757)
-
(2005)
Journal of Urology
, vol.173
, Issue.5
, pp. 1496-1501
-
-
Kim, H.L.1
Seligson, D.2
Liu, X.3
Janzen, N.4
Bui, M.H.T.5
Yu, H.6
Shi, T.7
Belldegrun, A.S.8
Horvath, S.9
Figlin, R.A.10
-
56
-
-
23844480769
-
Multiinstitutional European validation of the 2002 TNM staging system in conventional and papillary localized renal cell carcinoma
-
DOI 10.1002/cncr.21254
-
V Ficarra L Schips F Guille, et al. 2005 Multi-institutional European validation of the 2002 TNM staging system in conventional and papillary localized renal cell carcinoma Cancer 104 968 974 10.1002/cncr.21254 16007683 (Pubitemid 41170224)
-
(2005)
Cancer
, vol.104
, Issue.5
, pp. 968-974
-
-
Ficarra, V.1
Schips, L.2
Guille, F.3
Li, G.4
De La Taille, A.5
Galetti, T.P.6
Cindolo, L.7
Novara, G.8
Zigeuner, R.E.9
Bratti, E.10
Tostain, J.11
Altieri, V.12
Abbou, C.C.13
Artibani, W.14
Patard, J.-J.15
|