Effects of chronic ethanol consumption on levels of adipokines in visceral adipose tissues and sera of rats

Acta Pharmacologica Sinica

Volumn 31, Issue 4, 2010, Pages 461-469

  Yu, Heng Cai ^a,b   Li, Si Ying ^a   Cao, Ming Feng ^a,c   Jiang, Xiu Yun ^a,c   Feng, Li ^a,c   Zhao, Jia Jun ^a,c   Gao, Ling ^a  

^a SHANDONG PROVINCIAL HOSPITAL AFFILIATED TO SHANDONG UNIVERSITY   (China)

^b SHANDONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^c Shandong Academy of Clinical Medicine   (China)

Author keywords

Adipokines; Ethanol; Serum; Visceral adipose tissue

Indexed keywords

ADIPOCYTOKINE; ADIPONECTIN; ALCOHOL; CARTONECTIN; GLUCOSE; INSULIN; LEPTIN; NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE; RESISTIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ALCOHOL CONSUMPTION; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; ENZYME LINKED IMMUNOSORBENT ASSAY; EPIDIDYMIS FAT; GLUCOSE BLOOD LEVEL; HOMEOSTASIS; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; INTRAABDOMINAL FAT; LONG TERM EXPOSURE; MALE; NONHUMAN; PROTEIN BLOOD LEVEL; RAT; STOMACH TUBE;

ADIPOKINES; ADIPONECTIN; ANIMALS; ETHANOL; INSULIN RESISTANCE; INTRA-ABDOMINAL FAT; LEPTIN; MALE; NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE; RATS; RATS, WISTAR; RESISTIN;

EID: 77952214753     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2010.12     Document Type: Article

References (34)

1. Krug AW, Ehrhart-Bornstein M. Newly discovered endocrine functions of white adipose tissue: possible relevance in obesity-related diseases. Cell Mol Life Sci 2005; 62: 1359-1362
2. Rabe K, Lehrke M, Parhofer KG, Broedl UC. Adipokines and insulin resistance. Mol Med 2008; 14: 741-751
3. Campfield LA, Smith FJ, Guisez Y, Devos R, Burn P. Recombinant mouse ob protein: evidence for a peripheral signal linking adiposity and central neural networks. Science 1995; 269: 546-549
4. Maeda T, Abe M, Kurisu K, Jikko A, Furukawa S. Molecular cloning and characterization of a novel gene, CORS26, encoding putative secretory protein and its possible involvement in skeletal development. J Biol Chem 2001; 276: 3628-3634
5. Weigert J, Neumeier M, Schäffler A, Fleck M, Schölmerich J, Schütz C, et al. The adiponectin paralog CORS-26 has anti-inflammatory properties and is produced by human monocytic cells. FEBS Lett 2005; 579: 5565-5570
6. Wolfing B, Buechler C, Weigert J, Neumeier M, Aslanidis C, Schoelmerich J, et al. Effects of the new C1q/TNF-related protein (CTRP-3) "Cartonectin" on the adipocytic secretion adipokines. Obesity 2008; 16: 1481-1486
7. Basat O, Ucak S, Ozkurt H, Basak M, Seber S, Altuntas Y. Visceral adipose tissue as an indicator of insulin resistance in nonobese patients with new onset type 2 diabetes mellitus. Exp Clin Endocr Diab 2006; 114: 58-62.
8. Freedland ES. Role of a critical visceral adipose tissue threshold (CVATT) in metabolic syndrome: implications for controlling dietary carbohydrates: a review. Nutr Metab (Lond) 2004; 1: 12.
9. Fox CS, Massaro JM, Hoffmann U, Pou KM, Maurovich-Horvat P, Liu CY, et al. Abdominal visceral and subcutaneous adipose tissue compartments: association with metabolic risk factors in the Framingham Heart Study. Circulation 2007; 116: 39-48. (Pubitemid 47016245)
10. Rachdaoui N, Sebastian BM, Nagy LE. Chronic ethanol feeding impairs endothelin-1-stimulated glucose uptake via decreased G alpha 11 expression in rat adipocytes. Am J Physiol-Endocr M. 2003; 285: E303-10.
11. Kang L, Chen X, Sebastian BM, Pratt BT, Bederman IR, Alexander JC, et al. Chronic ethanol and triglyceride turnover in white adipose tissue in rats: inhibition of the anti-lipolytic action of insulin after chronic ethanol contributes to increased triglyceride degradation. J Biol Chem 2007; 282: 28465-28473
12. Wan Q, Liu Y, Guan Q, Gao L, Lee KO, Zhao J. Ethanol feeding impairs insulin-stimulated glucose uptake in isolated rat skeletal muscle: role of Gs alpha and cAMP. Alcohol Clin Exp Res 2005; 29: 1450-1456
13. Tian L, Hou X, Liu J, Zhang X, Sun N, Gao L, et al. Chronic ethanol consumption resulting in the downregulation of insulin receptor-b subunit, insulin receptor substrate-1, and glucose transporter 4 expression in rat cardiac muscles. Alcohol 2009; 43: 51-58
14. Pravdova E, Fickova M. Alcohol intake modulates hormonal activity of adipose tissue. Endocr Regul 2006; 40: 91-104.
15. Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985; 28: 412-419
16. Yoon YS, Oh SW, Baik HW, Park HS, Kim WY. Alcohol consumption and the metabolic syndrome in Korean adults: the 1998 Korean National Health and Nutrition Examination Survey. Am J Clin Nutr 2004; 80: 217-224
17. Wajchenberg BL, Giannella-Neto D, da Silva ME, Santos RF. Depotspecific hormonal characteristics of subcutaneous and visceral adipose tissue and their relation to the metabolic syndrome. Horm Metab Res 2002; 34: 616-621
18. Obradovic T, Meadows GG. Chronic alcohol consumption increases plasma leptin levels and alters leptin receptors in the hypothalamus and the perigonadal fat of C57BL/6 mice. Alcohol Clin Exp Res 2002; 26: 255-262
19. Maddalozzo GF, Turner RT, Edwards CH, Howe KS, Widrick JJ, Rosen CJ. Alcohol alters whole body composition, inhibits bone formation, and increases bone marrow adiposity in rats. Osteoporos Int 2009; 20: 1529-1538
20. Kalra SP. Appetite and body weight regulation: is it all in the brain? Neuron 1997; 19: 227-230
21. Fujioka S, Matsuzawa Y, Tokunaga K, Tarui S. Contribution of intraabdominal fat accumulation to the impairment of glucose and lipid metabolism in human obesity. Metabolism 1987; 36: 54-59
22. Goodpaster BH, Kelley DE, Wing RR, Meier A, Thaete FL. Effects of weight loss on regional fat distribution and insulin sensitivity in obesity. Diabetes 1999; 48: 839-847
23. Nakamura Y, Sekikawa A, Kadowaki T, Kadota A, Kadowaki S, Maegawa H, et al. Visceral and subcutaneous adiposity and adiponectin in middle-aged Japanese men: the ERA JUMP study. Obesity 2009; 17: 1269-1273
24. Wiest R, Moleda L, Farkas S, Scherer M, Kopp A, Wönckhaus U. Splanchnic concentrations and postprandial release of visceral adipokines. Metabolism 2009. doi: 10.1016/j.metabol.2009.09.011.
25. Marra F, Bertolani C. Adipokines in liver diseases. Hepatology 2009; 50: 957-969
26. Chen X, Sebastian BM, Nagy LE. Chronic ethanol feeding to rats decreases adiponectin secretion by subcutaneous adipocytes. Am J Physiol Endocrinol Metab 2007; 292: E621-8.
27. Xu A, Wang Y, Keshaw H, Xu LY, Lam KS, Cooper GJ. The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice. J Clin Invest 2003; 112: 91-100.
28. Pravdová E, Macho L, Hlavčova N, Ficková M. Long-time alcohol intake modifies resistin secretion and expression of resistin gene in adipose tissue. Gen Physiol Biophys 2007; 26: 221-229
29. Gu N, Han S, Fei L, Pan X, Guo M, Chen RH, et al. Resistin-binding peptide antagonizes role of resistin on white adipose tissue. Acta Pharmacol Sin 2007; 28: 221-226
30. Sierksma A, Patel H, Ouchi N, Kihara S, Funahashi T, Heine RJ, et al. Effect of moderate alcohol consumption on adiponectin, tumor necrosis factor-α, and insulin sensitivity. Diabetes Care 2004; 27: 184-189
31. Way JM, Görgün CZ, Tong Q, Uysal KT, Brown KK, Harrington WW, et al. Adipose tissue resistin expression is severely suppressed in obesity and stimulated by peroxisome proliferator-activated receptor gamma agonists. J Biol Chem 2001; 276: 25651-25653
32. Li M, Fisette A, Zhao XY, Deng JY, Mi J, Cianflone K. Serum resistin correlates with central obesity but weakly with insulin rsistance in Chinese children and adolescents. Int J Obesity 2009; 33: 424-439
33. Fukuhara A, Matsuda M, Nishizawa M, Segawa K, Tanaka M, Kishimoto K, et al. Visfatin: a protein secreted by visceral fat that mimics the effects of insulin. Science 2005; 307: 426-430 (Pubitemid 40139988)
34. Araki S, Dobashi K, Kubo K, Kawagoe R, Yamamoto Y, Kawada Y, et al. Plasma visfatin concentration as a surrogate marker for visceral fat accumulation in obese children. Obesity 2008; 16: 384-388